MX3276E - Procedimiento para la preparacion de 21- ester en cortico esteroides del acido [(1- bencil -1h- indazol -3- il ) oxi ] acetico - Google Patents
Procedimiento para la preparacion de 21- ester en cortico esteroides del acido [(1- bencil -1h- indazol -3- il ) oxi ] aceticoInfo
- Publication number
- MX3276E MX3276E MX002081U MX208176U MX3276E MX 3276 E MX3276 E MX 3276E MX 002081 U MX002081 U MX 002081U MX 208176 U MX208176 U MX 208176U MX 3276 E MX3276 E MX 3276E
- Authority
- MX
- Mexico
- Prior art keywords
- indazol
- oxy
- ester
- preparation
- acetic
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- ALEXXDVDDISNDU-JZYPGELDSA-N cortisol 21-acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O ALEXXDVDDISNDU-JZYPGELDSA-N 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 2
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 abstract 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 abstract 1
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 abstract 1
- 239000012346 acetyl chloride Substances 0.000 abstract 1
- BYFMCKSPFYVMOU-UHFFFAOYSA-N bendazac Chemical compound C12=CC=CC=C2C(OCC(=O)O)=NN1CC1=CC=CC=C1 BYFMCKSPFYVMOU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 229960001334 corticosteroids Drugs 0.000 abstract 1
- 229960004544 cortisone Drugs 0.000 abstract 1
- 229960000890 hydrocortisone Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a procedimeinto para la preparación de 21-éster en corticoesteroides del ácido [(1-bencil-1H-indazol-3-il) oxi] acético, caracterizado por el hecho de que cortisona, hidrocortisona predmisona y predmisolona se hacen reaccionar a la temperatura ambiente con cloruro de [(1-bencil-1H-indazol-3-il-oxi]-acetilo en presencia de un receptor de HCl.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48150/75A IT1036870B (it) | 1975-02-13 | 1975-02-13 | Derivati steroidei dell acido bendazolico |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX3276E true MX3276E (es) | 1980-08-14 |
Family
ID=11264844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX002081U MX3276E (es) | 1975-02-13 | 1976-01-14 | Procedimiento para la preparacion de 21- ester en cortico esteroides del acido [(1- bencil -1h- indazol -3- il ) oxi ] acetico |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4001219A (es) |
| JP (1) | JPS5339436B2 (es) |
| AR (1) | AR212329A1 (es) |
| CA (1) | CA1037466A (es) |
| CH (1) | CH606110A5 (es) |
| DE (1) | DE2601367C3 (es) |
| ES (1) | ES444231A1 (es) |
| FR (1) | FR2300570A1 (es) |
| GB (1) | GB1505461A (es) |
| IT (1) | IT1036870B (es) |
| MX (1) | MX3276E (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376767A (en) * | 1981-01-02 | 1983-03-15 | Merck & Co., Inc. | Pyridylmethyl esters of selected bio-affecting carboxylic acids |
| CA2136803A1 (en) * | 1993-12-22 | 1995-06-23 | Kazumi Ogata | Steroid derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH83A (fr) * | 1888-11-17 | 1889-01-10 | Fontainemelon Horlogerie | Perfectionnements apportés à la construction des montres de tous calibres |
| GB919830A (en) * | 1959-07-16 | 1963-02-27 | Leo Ab | Esters of cortical steroid hormones |
| GB1272841A (en) * | 1969-01-23 | 1972-05-03 | Leo Ab | New corticoid steroid compounds of cytostatic interest |
| DE2064859C3 (de) * | 1970-12-30 | 1980-05-22 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue 6 a -Fluor-16 a , 18dimethyl-l,4-pregnadien-3,20-dion Derivate, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
-
1975
- 1975-02-13 IT IT48150/75A patent/IT1036870B/it active
- 1975-12-18 CH CH1644775A patent/CH606110A5/xx not_active IP Right Cessation
-
1976
- 1976-01-06 JP JP108576A patent/JPS5339436B2/ja not_active Expired
- 1976-01-09 GB GB873/76A patent/GB1505461A/en not_active Expired
- 1976-01-09 US US05/647,749 patent/US4001219A/en not_active Expired - Lifetime
- 1976-01-12 ES ES444231A patent/ES444231A1/es not_active Expired
- 1976-01-14 MX MX002081U patent/MX3276E/es unknown
- 1976-01-15 DE DE2601367A patent/DE2601367C3/de not_active Expired
- 1976-02-10 AR AR262196A patent/AR212329A1/es active
- 1976-02-12 CA CA245,872A patent/CA1037466A/en not_active Expired
- 1976-02-13 FR FR7604068A patent/FR2300570A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE2601367B2 (de) | 1981-04-09 |
| ES444231A1 (es) | 1977-05-01 |
| FR2300570B1 (es) | 1979-09-21 |
| CH606110A5 (es) | 1978-10-13 |
| JPS5195071A (es) | 1976-08-20 |
| DE2601367A1 (de) | 1976-08-26 |
| US4001219A (en) | 1977-01-04 |
| IT1036870B (it) | 1979-10-30 |
| JPS5339436B2 (es) | 1978-10-21 |
| AR212329A1 (es) | 1978-06-30 |
| GB1505461A (en) | 1978-03-30 |
| FR2300570A1 (fr) | 1976-09-10 |
| CA1037466A (en) | 1978-08-29 |
| DE2601367C3 (de) | 1982-04-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES298429A1 (es) | Un metodo de producir mono y poliesteres de hormonas esteroides estrëgenas, andrëgenas y corticoides | |
| US2838534A (en) | 7-lower alkyl steroids and process | |
| GB1089945A (en) | Steroidal-6-spirocyclopropyl-4-en-3-ones | |
| ES444231A1 (es) | Procedimiento para la preparacion de esteres del acido (1- bencil-1h-indazoil-3-il)-oxi)-acetico. | |
| IE36592B1 (en) | Process for the manufacture of pregnane derivatives | |
| GB854343A (en) | Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids | |
| GB2018257A (en) | 11 beta -Silylation in corticoid synthesis | |
| GB1037891A (en) | Process for the manufacture of 19-nor-steroids | |
| US3087939A (en) | Method for the production of 3-keto steroids from the corresponding 3-formates | |
| GB817175A (en) | Improvements in or relating to cyclopentanopolyhydrophenanthrene compounds | |
| GB916951A (en) | New process for the preparation of 6ª--fluoro-steroids | |
| GB944643A (en) | New steroid compounds of the pregnane series and a process for their manufacture | |
| GB904994A (en) | Cyclopentanopolyhydrophenanthrene derivatives and method for producing same | |
| GB918408A (en) | Esters of 21-hydroxy steroids and process for preparation | |
| GB877227A (en) | Improvements in or relating to the production of steroid compounds, and the compounds thus produced | |
| GB1240698A (en) | Methylenation process and reagent | |
| GB811867A (en) | Dehydro-compounds of the steroid series and process of making same | |
| GB899375A (en) | Improvements in or relating to the manufacture of steroids | |
| FR2036997A1 (en) | Thermpentic steroidal sulphonate esters | |
| GB1037772A (en) | Improvements in or relating to í¸-steroid compounds | |
| GB1117406A (en) | Process for dehydrohalogenating organic compounds | |
| GB792727A (en) | Improvements in or relating to cyclopentanophenanthrene compounds and the preparation thereof | |
| GB799494A (en) | Dehydrocortical hormones | |
| ES455933A1 (es) | Procedimiento para la preparacion de nuevos esteroides. | |
| GB924253A (en) | í¸-allopregnene and process for its manufacture |