MX337048B - Vacuna marcadora para la fiebre porcina clasica. - Google Patents

Vacuna marcadora para la fiebre porcina clasica.

Info

Publication number
MX337048B
MX337048B MX2012013419A MX2012013419A MX337048B MX 337048 B MX337048 B MX 337048B MX 2012013419 A MX2012013419 A MX 2012013419A MX 2012013419 A MX2012013419 A MX 2012013419A MX 337048 B MX337048 B MX 337048B
Authority
MX
Mexico
Prior art keywords
swine fever
classical swine
marker vaccine
relates
marker
Prior art date
Application number
MX2012013419A
Other languages
English (en)
Other versions
MX2012013419A (es
Inventor
Martin Beer
Sandra Blome
Immanuel Leifer
Original Assignee
Riemser Arzneimittel Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riemser Arzneimittel Ag filed Critical Riemser Arzneimittel Ag
Publication of MX2012013419A publication Critical patent/MX2012013419A/es
Publication of MX337048B publication Critical patent/MX337048B/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/18—Togaviridae; Flaviviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención se refiere a una vacuna marcadora para el tratamiento profiláctico de la fiebre porcina clásica que comprende el virus vivo modificado atenuado de la fiebre porcina clásica. La secuencia viral de aminoácidos del epítope TAV de la proteína E2 comprende una secuencia diferente de la de un virus de tipo silvestre de la fiebre porcina clásica. La invención se refiere a composiciones farmacéuticas de la vacuna marcadora. La invención también se refiere a un procedimiento para fabricar las vacunas marcadoras para la prevención de la fiebre porcina clásica usando presión selectiva de anticuerpos.
MX2012013419A 2010-05-18 2011-05-18 Vacuna marcadora para la fiebre porcina clasica. MX337048B (es)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
EP10075206 2010-05-18
EP10075205 2010-05-18
EP10075207 2010-05-18
DE102010017006 2010-05-18
EP10075759 2010-12-17
EP10075760 2010-12-17
EP11159207 2011-03-22
PCT/EP2011/002624 WO2011144360A1 (en) 2010-05-18 2011-05-18 Marker vaccine for classical swine fever

Publications (2)

Publication Number Publication Date
MX2012013419A MX2012013419A (es) 2013-01-28
MX337048B true MX337048B (es) 2016-02-11

Family

ID=44461927

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012013419A MX337048B (es) 2010-05-18 2011-05-18 Vacuna marcadora para la fiebre porcina clasica.

Country Status (20)

Country Link
US (1) US9315873B2 (es)
EP (1) EP2571519B1 (es)
KR (1) KR101845571B1 (es)
CN (1) CN102905725B (es)
BR (1) BR112012029145B8 (es)
CA (1) CA2801897C (es)
CY (1) CY1118060T1 (es)
DK (1) DK2571519T3 (es)
EA (1) EA031518B1 (es)
ES (1) ES2593965T3 (es)
HR (1) HRP20161225T1 (es)
HU (1) HUE029385T2 (es)
MX (1) MX337048B (es)
PH (1) PH12012502273A1 (es)
PL (1) PL2571519T3 (es)
PT (1) PT2571519T (es)
RS (1) RS55214B1 (es)
SI (1) SI2571519T1 (es)
WO (1) WO2011144360A1 (es)
ZA (1) ZA201208194B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103159858B (zh) * 2013-02-26 2014-06-04 中国农业科学院上海兽医研究所 猪瘟分支肽及其应用
WO2015177369A1 (en) * 2014-05-23 2015-11-26 Boehringer Ingelheim Vetmedica Gmbh Recombinant classical swine fever virus (csfv) comprising substitution in the tav epitope of the e2 protein
CN118620043B (zh) * 2024-06-11 2024-11-15 宁夏农林科学院动物科学研究所(宁夏草畜工程技术研究中心) 双价牛病毒性腹泻病毒e2亚单位疫苗、制备方法及应用
CN121021653B (zh) * 2025-10-30 2026-04-03 吉林大学 猪瘟病毒e2蛋白标记亚单位疫苗及其配套的血清学鉴别诊断试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU220746B1 (hu) * 1994-06-17 2002-05-28 Instituut Voor Veehouderij En Diergezondheid Pestivírustörzsekből izolált nukleotidszekvenciák, az általuk kódolt polipeptidek és ezek alkalmazása pestivírus-fertőzések diagnosztizálására és megelőzésére
US8846055B2 (en) * 2006-05-30 2014-09-30 The United States Of America, As Represented By The Secretary Of Agriculture Virulence determinant within the E2 structural glycoprotein of classical swine fever virus
US8133495B2 (en) * 2007-05-22 2012-03-13 The United States Of America As Represented By The Secretary Of Agriculture Live attenuated antigenically marked classical swine fever virus
EP2202298A1 (en) * 2008-12-23 2010-06-30 Stichting Dienst Landbouwkundig Onderzoek Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV

Also Published As

Publication number Publication date
PL2571519T3 (pl) 2017-07-31
EA031518B1 (ru) 2019-01-31
HRP20161225T1 (hr) 2016-12-02
US9315873B2 (en) 2016-04-19
BR112012029145A2 (pt) 2020-07-07
RS55214B1 (sr) 2017-02-28
KR101845571B1 (ko) 2018-04-04
CA2801897C (en) 2019-01-15
BR112012029145B1 (pt) 2021-09-14
CY1118060T1 (el) 2017-06-28
CN102905725A (zh) 2013-01-30
KR20130109008A (ko) 2013-10-07
EA201270794A1 (ru) 2013-04-30
BR112012029145B8 (pt) 2022-03-08
PT2571519T (pt) 2016-10-03
ES2593965T3 (es) 2016-12-14
SI2571519T1 (sl) 2017-01-31
CN102905725B (zh) 2016-01-20
PH12012502273A1 (en) 2013-02-04
EP2571519B1 (en) 2016-06-29
EP2571519A1 (en) 2013-03-27
HUE029385T2 (en) 2017-02-28
US20130129762A1 (en) 2013-05-23
DK2571519T3 (en) 2016-10-17
ZA201208194B (en) 2014-01-29
WO2011144360A1 (en) 2011-11-24
MX2012013419A (es) 2013-01-28
EA201270794A8 (ru) 2017-10-31
CA2801897A1 (en) 2011-11-24

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