MX342625B - Combinaciones antitumorales que contienen anticuerpos que reconocen específicamente cd38 y melfalan. - Google Patents

Combinaciones antitumorales que contienen anticuerpos que reconocen específicamente cd38 y melfalan.

Info

Publication number
MX342625B
MX342625B MX2011005670A MX2011005670A MX342625B MX 342625 B MX342625 B MX 342625B MX 2011005670 A MX2011005670 A MX 2011005670A MX 2011005670 A MX2011005670 A MX 2011005670A MX 342625 B MX342625 B MX 342625B
Authority
MX
Mexico
Prior art keywords
melfalan
antitumoral
specifically recognize
antibody
containing antibodies
Prior art date
Application number
MX2011005670A
Other languages
English (en)
Spanish (es)
Other versions
MX2011005670A (es
Inventor
Vrignaud Patricia
Lejeune Pascale
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40578382&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX342625(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2011005670A publication Critical patent/MX2011005670A/es
Publication of MX342625B publication Critical patent/MX342625B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2011005670A 2008-11-28 2009-11-27 Combinaciones antitumorales que contienen anticuerpos que reconocen específicamente cd38 y melfalan. MX342625B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08291116A EP2191840A1 (fr) 2008-11-28 2008-11-28 Combinaisons antitumorales contenant des anticorps reconnaissant spécifiquement les CD38 et melphalan
PCT/IB2009/055389 WO2010061357A1 (fr) 2008-11-28 2009-11-27 Associations antitumorales contenant des anticorps reconnaissant spécifiquement cd38 et du melphalan

Publications (2)

Publication Number Publication Date
MX2011005670A MX2011005670A (es) 2011-09-30
MX342625B true MX342625B (es) 2016-10-06

Family

ID=40578382

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011005670A MX342625B (es) 2008-11-28 2009-11-27 Combinaciones antitumorales que contienen anticuerpos que reconocen específicamente cd38 y melfalan.

Country Status (33)

Country Link
US (1) US9259406B2 (fr)
EP (2) EP2191840A1 (fr)
JP (3) JP2012510461A (fr)
KR (1) KR101733252B1 (fr)
CN (1) CN102264385B (fr)
AR (1) AR074219A1 (fr)
AU (1) AU2009321249B2 (fr)
BR (1) BRPI0921864B1 (fr)
CA (1) CA2744990C (fr)
CL (1) CL2011001254A1 (fr)
CO (1) CO6440557A2 (fr)
CR (1) CR20110280A (fr)
EA (1) EA026867B1 (fr)
EC (1) ECSP11011062A (fr)
HN (1) HN2011001417A (fr)
IL (1) IL213116B (fr)
MA (1) MA32896B1 (fr)
ME (1) ME01136B (fr)
MX (1) MX342625B (fr)
MY (1) MY164577A (fr)
NI (1) NI201100105A (fr)
NZ (1) NZ593027A (fr)
PA (1) PA8850101A1 (fr)
PE (1) PE20120340A1 (fr)
PY (1) PY09043215A (fr)
SG (1) SG171820A1 (fr)
SV (1) SV2011003924A (fr)
TN (1) TN2011000232A1 (fr)
TW (1) TWI454260B (fr)
UA (1) UA107069C2 (fr)
UY (1) UY32263A (fr)
WO (1) WO2010061357A1 (fr)
ZA (1) ZA201103925B (fr)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0816777B2 (ja) 1988-10-13 1996-02-21 富士写真フイルム株式会社 画像形成方法
EP2191840A1 (fr) 2008-11-28 2010-06-02 Sanofi-Aventis Combinaisons antitumorales contenant des anticorps reconnaissant spécifiquement les CD38 et melphalan
EP3072961A1 (fr) 2010-04-16 2016-09-28 Children's Medical Center Corporation Expression de polypeptides prolongée à partir d'arn modifiés, synthétiques et leurs utilisations
CA2807552A1 (fr) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Acides nucleiques modifies et leurs procedes d'utilisation
NZ607473A (en) 2010-09-27 2014-11-28 Morphosys Ag Anti-cd38 antibody and lenalidomide or bortezomib for the treatment of multiple myeloma and nhl
ES3005233T3 (en) 2010-10-01 2025-03-14 Modernatx Inc Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
UA112170C2 (uk) * 2010-12-10 2016-08-10 Санофі Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб
JOP20210044A1 (ar) 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP2763701B1 (fr) 2011-10-03 2018-12-19 Moderna Therapeutics, Inc. Nucléosides, nucléotides et acides nucléiques modifiés, et leurs utilisations
JP2015501844A (ja) 2011-12-16 2015-01-19 モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. 修飾ヌクレオシド、ヌクレオチドおよび核酸組成物
US9254311B2 (en) 2012-04-02 2016-02-09 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
WO2013151663A1 (fr) 2012-04-02 2013-10-10 modeRNA Therapeutics Polynucléotides modifiés pour la production de protéines membranaires
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
ES2658953T3 (es) * 2012-09-25 2018-03-13 Morphosys Ag Combinaciones y usos de los mismos
ES2921623T3 (es) 2012-11-26 2022-08-30 Modernatx Inc ARN modificado terminalmente
US10342869B2 (en) 2012-12-07 2019-07-09 The Regents Of The University Of California Compositions comprising anti-CD38 antibodies and lenalidomide
UA118255C2 (uk) * 2012-12-07 2018-12-26 Санофі Композиція, яка містить антитіло до cd38 і леналідомід
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
WO2015048744A2 (fr) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucléotides codant des polypeptides de modulation immunitaire
KR20160067219A (ko) 2013-10-03 2016-06-13 모더나 세라퓨틱스, 인코포레이티드 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
EP3063173B1 (fr) * 2013-10-31 2020-07-29 Sanofi Anticorps anti-cd38 spécifiques pour le traitement de cancers humains
US9603927B2 (en) 2014-02-28 2017-03-28 Janssen Biotech, Inc. Combination therapies with anti-CD38 antibodies
US9732154B2 (en) 2014-02-28 2017-08-15 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
US10617757B2 (en) 2014-08-08 2020-04-14 The Regents Of The University Of California Methods for treating multiple myeloma
PE20170676A1 (es) 2014-09-09 2017-05-22 Janssen Biotech Inc Terapias de combinacion con anticuerpos anti-cd38
EA202092609A1 (ru) 2014-12-04 2021-10-29 Янссен Байотек, Инк. Антитела к cd38 для лечения острого миелолейкоза
CA2986594C (fr) 2015-05-20 2025-06-10 Tufts Medical Center, Inc. Anticorps anti-cd38 pour le traitement de l’amyloïdose à chaînes légères et d’autres tumeurs malignes hématologiques positives à cd38
CN107708734B (zh) 2015-06-22 2022-01-11 詹森生物科技公司 用抗cd38抗体和生存素抑制剂联合治疗血红素恶性肿瘤
US20170044265A1 (en) 2015-06-24 2017-02-16 Janssen Biotech, Inc. Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38
US10781261B2 (en) 2015-11-03 2020-09-22 Janssen Biotech, Inc. Subcutaneous formulations of anti-CD38 antibodies and their uses
HUE053366T2 (hu) 2015-11-03 2021-06-28 Janssen Biotech Inc Szubkután anti-CD38-ellenanyag-készítmények és alkalmazásuk
US20190233533A1 (en) 2016-06-28 2019-08-01 Umc Utrecht Holding B.V. Treatment Of IgE-Mediated Diseases With Antibodies That Specifically Bind CD38
EP3484923A1 (fr) 2016-07-15 2019-05-22 Takeda Pharmaceutical Company Limited Méthodes et matériaux permettant d'évaluer une réponse à des traitements de déplétion de plasmoblastes et de plasmocytes
WO2019035938A1 (fr) 2017-08-16 2019-02-21 Elstar Therapeutics, Inc. Molécules multispécifiques se liant à bcma et leurs utilisations
CN111565751A (zh) 2017-10-31 2020-08-21 詹森生物科技公司 治疗高危多发性骨髓瘤的方法
US20210145778A1 (en) * 2018-01-01 2021-05-20 Orbicular Pharmaceutical Technologies Pvt. Ltd. Stable Liquid Compositions of Melphalan
US12371506B2 (en) 2018-01-12 2025-07-29 Takeda Pharmaceutical Company Limited Subcutaneous administration of anti-CD38 antibodies
EP3856226B1 (fr) 2018-09-28 2026-02-18 President and Fellows of Harvard College Reprogrammation cellulaire pour inverser le vieillissement et favoriser la régénération des organes et tissus
US12274733B2 (en) 2018-09-28 2025-04-15 President And Fellows Of Harvard College Cellular reprogramming to reverse aging and promote organ and tissue regeneration
EP3856260A1 (fr) 2018-09-28 2021-08-04 President and Fellows of Harvard College Transactivateurs de tétracycline inverses mutants pour l'expression de gènes
JP7687956B2 (ja) 2019-03-15 2025-06-03 モルフォシス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 自己抗体介在性自己免疫疾患の処置のための、抗cd38抗体及びその医薬組成物
US11655302B2 (en) 2019-06-10 2023-05-23 Sanofi Anti-CD38 antibodies and formulations
TW202606756A (zh) 2019-12-05 2026-02-16 美商賽諾菲阿凡提斯美國有限責任公司 用於皮下投予之抗cd38抗體的調配物
CA3204187A1 (fr) 2021-01-14 2022-07-21 Stefan Steidl Anticorps anti-cd38 et leurs utilisations
TW202302642A (zh) 2021-03-01 2023-01-16 德商莫菲西斯公司 用於治療抗體介導移植物排斥用途之抗cd38抗體
TW202321303A (zh) 2021-07-19 2023-06-01 德商莫菲西斯公司 抗pla2r自體抗體媒介膜性腎病變之治療
US12252518B2 (en) 2023-01-06 2025-03-18 Life Biosciences, Inc. Methods of treating non-arteritic anterior ischemic optic neuropathy

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB750155A (en) 1953-03-17 1956-06-13 Nat Res Dev Substituted alanines
US3032585A (en) 1954-12-03 1962-05-01 Nat Res Dev Process for the production of p-bis-(2-chloroethyl)-aminophenylalanine
US4444887A (en) 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4716111A (en) 1982-08-11 1987-12-29 Trustees Of Boston University Process for producing human antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
ES2284161T3 (es) 1990-01-12 2007-11-01 Amgen Fremont Inc. Generacion de anticuerpos xenogenicos.
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
ATE255131T1 (de) 1991-06-14 2003-12-15 Genentech Inc Humanisierter heregulin antikörper
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
EP0822830B1 (fr) 1995-04-27 2008-04-02 Amgen Fremont Inc. Anticorps anti-IL-8 dérivés de xenosouris immunisées
WO1996034096A1 (fr) 1995-04-28 1996-10-31 Abgenix, Inc. Anticorps humains derives de xeno-souris immunisees
US5916771A (en) 1996-10-11 1999-06-29 Abgenix, Inc. Production of a multimeric protein by cell fusion method
ATE549918T1 (de) 1996-12-03 2012-04-15 Amgen Fremont Inc Menschliche antikörper, die ausdrücklich menschliches tnf alpha binden
TR199902553T2 (xx) 1997-04-14 2000-03-21 Micromet Gesellschaft F�R Biomedizinische Forschung Mbh �nsan v�cuduna kar�� antijen resept�rlerinin �retimi i�in yeni metod ve kullan�mlar�.
US6235883B1 (en) 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
JP2003524587A (ja) * 1998-06-05 2003-08-19 マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ 多発性骨髄腫を処置するための、cd38に対する、遺伝子操作した抗体の使用
US7223397B1 (en) 1999-01-07 2007-05-29 Research Development Foundation Potentiation of anti-CD38-Immunotoxin cytotoxicity
GB0221574D0 (en) 2002-09-17 2002-10-23 Isis Innovation Treatments
ES2541436T3 (es) 2004-02-06 2015-07-20 Morphosys Ag Anticuerpos humanos anti-CD38 y usos para ellos
EP3312196B1 (fr) * 2005-03-23 2019-07-17 Genmab A/S Anticorps dirigés contre cd38 pour le traitement du myélome multiple
AU2007302448C1 (en) 2006-09-26 2019-02-14 Genmab A/S Combination treatment of CD38-expressing tumors
US20080092384A1 (en) * 2006-10-16 2008-04-24 Schaake Mark D Installation of Middle Bearing for a Crankshaft
EP1914242A1 (fr) 2006-10-19 2008-04-23 Sanofi-Aventis Nouveau anticorps Anti-CD38 pour le traitement du cancer
EP2191841A1 (fr) 2008-11-28 2010-06-02 Sanofi-Aventis Combinaisons antitumorales contenant des anticorps reconnaissant spécifiquement les CD38 et vincristine
EP2191840A1 (fr) 2008-11-28 2010-06-02 Sanofi-Aventis Combinaisons antitumorales contenant des anticorps reconnaissant spécifiquement les CD38 et melphalan
EP2191843A1 (fr) 2008-11-28 2010-06-02 Sanofi-Aventis Combinaisons antitumorales contenant des anticorps reconnaissant spécifiquement les CD38 et cyclophosphamide

Also Published As

Publication number Publication date
MX2011005670A (es) 2011-09-30
PA8850101A1 (es) 2010-07-27
KR101733252B1 (ko) 2017-05-08
AU2009321249B2 (en) 2016-06-09
WO2010061357A1 (fr) 2010-06-03
US20110274686A1 (en) 2011-11-10
JP2012510461A (ja) 2012-05-10
EP2191840A1 (fr) 2010-06-02
NZ593027A (en) 2012-12-21
CA2744990C (fr) 2019-05-07
HN2011001417A (es) 2014-01-13
NI201100105A (es) 2011-12-13
JP2015205890A (ja) 2015-11-19
US9259406B2 (en) 2016-02-16
JP6148696B2 (ja) 2017-06-14
BRPI0921864A2 (en) 2018-10-09
CN102264385A (zh) 2011-11-30
ECSP11011062A (es) 2011-07-29
PY09043215A (es) 2013-11-01
CN102264385B (zh) 2015-05-20
IL213116A0 (en) 2011-07-31
IL213116B (en) 2018-11-29
SG171820A1 (en) 2011-07-28
TN2011000232A1 (en) 2012-12-17
BRPI0921864B1 (pt) 2022-11-16
CO6440557A2 (es) 2012-05-15
AU2009321249A1 (en) 2010-06-03
UY32263A (es) 2010-06-30
EA201100864A1 (ru) 2011-12-30
PE20120340A1 (es) 2012-04-17
MY164577A (en) 2018-01-15
AR074219A1 (es) 2010-12-29
CL2011001254A1 (es) 2012-01-27
EA026867B1 (ru) 2017-05-31
EP2370094A1 (fr) 2011-10-05
TW201023855A (en) 2010-07-01
HK1164165A1 (en) 2012-09-21
SV2011003924A (es) 2011-10-07
JP2017141233A (ja) 2017-08-17
CR20110280A (es) 2011-09-20
ZA201103925B (en) 2012-09-26
UA107069C2 (uk) 2014-11-25
KR20110096550A (ko) 2011-08-30
ME01136B (me) 2013-03-20
TWI454260B (zh) 2014-10-01
MA32896B1 (fr) 2011-12-01
CA2744990A1 (fr) 2010-06-03

Similar Documents

Publication Publication Date Title
CO6440557A2 (es) Combinaciones ntitumorales que contienen anticuerpos que reconocen especificamente cd38 y melfalan
MX344973B (es) Combinaciones antitumorales que contienen anticuerpos que reconocen especificamente la cd38 y la citarabina.
ES2675847T3 (es) Nuevo anticuerpo anti-DR5
MX337873B (es) Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12.
AR122771A2 (es) Anticuerpos para el tratamiento del cáncer, conjugado, composición farmacéutica, ácido nucleico y célula huésped
CO6331346A2 (es) Anticuerpos anti-factor d humanizados, secuencias, composiciones, kit y articulo de fabricacion del mismo
AR083747A1 (es) Anticuerpos anti-il-23
AR117911A2 (es) Anticuerpo anti-158p1d7 o fragmento de unión a antígeno del mismo, conjugado fármaco-anticuerpo, composición farmacéutica y sus usos
UY30776A1 (es) Anticuerpos cd44
MX2009012343A (es) Regiones fc (sc fc) de cadena sencilla, polipeptidos de enlace que comprenden las mismas, y metodos relacionados con ello.
CO6361946A2 (es) Combuinaciones antitumorales que contienen anticuperos que reconocen especificamente cd38 y vincristina
CY1119647T1 (el) Αντισωματα προσδεσης αλβουμινης και τμηματα προσδεσης αυτων
ES2685823T3 (es) Anticuerpos antagonistas anti-CD40
EA201491569A1 (ru) МОДИФИЦИРОВАННЫЕ БИСПЕЦИФИЧЕСКИЕ АНТИТЕЛА IgG4 С СИММЕТРИЧНОЙ ПОСЛЕДОВАТЕЛЬНОСТЬЮ
AR109355A2 (es) Moléculas de unión al receptor ox40 humano
ES2670621T3 (es) Anticuerpos que se unen a OX40 y sus usos
PE20140004A1 (es) Combinaciones antitumorales que contienen anticuerpos que reconocen especificamente cd38 y bortezomib
CO6700829A2 (es) Moduladores novedosos y métodos de uso
EA201101593A1 (ru) КОМПОЗИЦИИ И СПОСОБЫ, ПРЕДНАЗНАЧЕННЫЕ ДЛЯ НАПРАВЛЕННОГО ВОЗДЕЙСТВИЯ АНТИТЕЛ НА БЕЛОК С3b СИСТЕМЫ КОМПЛЕМЕНТА
UA113728C2 (xx) Фармацевтична композиція, яка містить антитіло до pcsk9 людини
EA201490677A1 (ru) Связывающие антиген cd27l белки
CO6251325A2 (es) Un anticuerpo humano o humanizado, o un fragmento del mismo con una region de enlace de antigeno que es especifica para dirigir la proteina al receptor de limfoproteina estromal timica humana (htslpr)
CO6430469A2 (es) Anticuerpos humanizados que se unen a cd19 y sus usos
AR065312A1 (es) Nuevos anticuerpos
DK2352763T4 (da) Bispecifikke enkeltkædede antistoffer med specificitet for højmolekylære målantigener

Legal Events

Date Code Title Description
FG Grant or registration