MX344355B - Uso de inhibidores de erbb3 en el tratamiento de canceres de mama triple negativos y de tipo basal. - Google Patents

Uso de inhibidores de erbb3 en el tratamiento de canceres de mama triple negativos y de tipo basal.

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Publication number
MX344355B
MX344355B MX2012010226A MX2012010226A MX344355B MX 344355 B MX344355 B MX 344355B MX 2012010226 A MX2012010226 A MX 2012010226A MX 2012010226 A MX2012010226 A MX 2012010226A MX 344355 B MX344355 B MX 344355B
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MX
Mexico
Prior art keywords
basal
triple negative
erbb3
patient
treatment
Prior art date
Application number
MX2012010226A
Other languages
English (en)
Other versions
MX2012010226A (es
Inventor
Moyo Victor
Garcia Gabriela
Original Assignee
Merrimack Pharmaceuticals Inc *
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44513103&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX344355(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merrimack Pharmaceuticals Inc * filed Critical Merrimack Pharmaceuticals Inc *
Publication of MX2012010226A publication Critical patent/MX2012010226A/es
Publication of MX344355B publication Critical patent/MX344355B/es

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    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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Abstract

La presente invención se refiere a métodos para suprimir el crecimiento de tumores de mama triple negativos y tumores de mama de tipo basal al poner en contacto las células tumorales con un inhibidor de ErbB3, por ej., un anticuerpo anti-ErbB3. También se proporcionan métodos para tratar el cáncer de mama triple negativo o cáncer de mama de tipo basal en un paciente mediante la administración al paciente de un inhibidor de ErbB3, por ej., un anticuerpo antiErbB3. Los métodos de tratamiento pueden comprender además seleccionar un paciente que tiene un cáncer de mama triple negativo o un cáncer de mama de tipo basal y luego administrar un inhibidor de ErbB3 al paciente. Los métodos de tratamiento también pueden comprender administrar al menos un agente anticanceroso adicional al paciente en combinación con el inhibidor de ErbB3.
MX2012010226A 2010-03-11 2011-03-11 Uso de inhibidores de erbb3 en el tratamiento de canceres de mama triple negativos y de tipo basal. MX344355B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31289510P 2010-03-11 2010-03-11
PCT/US2011/028129 WO2011112953A2 (en) 2010-03-11 2011-03-11 Use of erbb3 inhibitors in the treatment of triple negative and basal-like breast cancers

Publications (2)

Publication Number Publication Date
MX2012010226A MX2012010226A (es) 2013-01-29
MX344355B true MX344355B (es) 2016-12-14

Family

ID=44513103

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012010226A MX344355B (es) 2010-03-11 2011-03-11 Uso de inhibidores de erbb3 en el tratamiento de canceres de mama triple negativos y de tipo basal.

Country Status (20)

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US (4) US8895001B2 (es)
EP (2) EP2544680B1 (es)
JP (2) JP2013522237A (es)
KR (1) KR101798679B1 (es)
CN (1) CN102858335B (es)
AU (1) AU2011224186C1 (es)
BR (1) BR112012022802A2 (es)
CA (1) CA2792327C (es)
DK (1) DK2544680T3 (es)
EA (1) EA201201186A1 (es)
ES (1) ES2535503T3 (es)
IL (1) IL221693A (es)
MX (1) MX344355B (es)
NZ (1) NZ602084A (es)
PL (1) PL2544680T3 (es)
PT (1) PT2544680E (es)
SG (1) SG183532A1 (es)
UA (1) UA111149C2 (es)
WO (1) WO2011112953A2 (es)
ZA (1) ZA201206425B (es)

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