MX366639B - Derivado de bifenilo novedoso y metodo para preparar el mismo. - Google Patents

Derivado de bifenilo novedoso y metodo para preparar el mismo.

Info

Publication number
MX366639B
MX366639B MX2016001200A MX2016001200A MX366639B MX 366639 B MX366639 B MX 366639B MX 2016001200 A MX2016001200 A MX 2016001200A MX 2016001200 A MX2016001200 A MX 2016001200A MX 366639 B MX366639 B MX 366639B
Authority
MX
Mexico
Prior art keywords
biphenyl derivative
disease
novel biphenyl
isomer
pharmaceutically acceptable
Prior art date
Application number
MX2016001200A
Other languages
English (en)
Spanish (es)
Other versions
MX2016001200A (es
Inventor
Kim Soon-Hoe
Yeon Kim Mi-
Hak Choi Sung-
Bin Im Weon-
Hwan Cho Chong-
Ho CHOI Sun-
Sang Park Jung-
Jung Lee Min-
Hun Cho Kang-
Original Assignee
Dong A St Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong A St Co Ltd filed Critical Dong A St Co Ltd
Publication of MX2016001200A publication Critical patent/MX2016001200A/es
Publication of MX366639B publication Critical patent/MX366639B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
MX2016001200A 2013-07-30 2014-07-17 Derivado de bifenilo novedoso y metodo para preparar el mismo. MX366639B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020130090175A KR101538846B1 (ko) 2013-07-30 2013-07-30 신규한 바이페닐 유도체 및 그의 제조방법
PCT/KR2014/006483 WO2015016511A1 (fr) 2013-07-30 2014-07-17 Nouveau dérivé de biphényle, et son procédé de préparation

Publications (2)

Publication Number Publication Date
MX2016001200A MX2016001200A (es) 2016-08-17
MX366639B true MX366639B (es) 2019-07-17

Family

ID=52431993

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016001200A MX366639B (es) 2013-07-30 2014-07-17 Derivado de bifenilo novedoso y metodo para preparar el mismo.

Country Status (19)

Country Link
US (1) US9828339B2 (fr)
EP (1) EP3029026B1 (fr)
JP (1) JP6109425B2 (fr)
KR (1) KR101538846B1 (fr)
CN (1) CN105555761B (fr)
AU (1) AU2014297144B2 (fr)
CA (1) CA2919624C (fr)
ES (1) ES2710389T3 (fr)
IL (1) IL243830B (fr)
MX (1) MX366639B (fr)
MY (1) MY175411A (fr)
PH (1) PH12016500197B1 (fr)
PT (1) PT3029026T (fr)
RU (1) RU2644234C2 (fr)
SG (1) SG11201600624RA (fr)
TR (1) TR201901449T4 (fr)
UA (1) UA116480C2 (fr)
WO (1) WO2015016511A1 (fr)
ZA (1) ZA201601227B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102239776B1 (ko) 2016-08-26 2021-04-13 동아에스티 주식회사 (r)-(1-메틸피롤리딘-3-일)메틸(3'-클로로-4'-플루오로-[1,1'-비페닐]-2-일)카바메이트의 신규염 및 이의 결정형
MY200068A (en) * 2016-08-26 2023-12-06 Dong A St Co Ltd Novel salt of (r)-(1-methylpyrrolidine-3-yl)methyl(3'-chloro-4'-fluoro-[1,1'-biphenyl]-2-yl)carbamate and a crystal form thereof
KR102611847B1 (ko) * 2023-03-27 2023-12-12 주식회사 이플라스크 무스카린 수용체 길항 활성을 갖는 신규한 피롤리디늄 화합물 및 이의 용도

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1140447A (zh) * 1994-02-10 1997-01-15 山之内制药株式会社 新的氨基甲酸酯衍生物及其药物组合物
WO1995021820A1 (fr) * 1994-02-10 1995-08-17 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive du carbamate et composition correspondante
US5613402A (en) * 1995-06-06 1997-03-25 Itt Automotive, Inc. Adjustable set bearing
AU783095B2 (en) 1999-12-07 2005-09-22 Theravance Biopharma R&D Ip, Llc Carbamate derivatives having muscarinic receptor antagonist activity
TW200534855A (en) 2004-01-13 2005-11-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
EP1781607A2 (fr) 2004-08-19 2007-05-09 Ranbaxy Laboratories Limited Derives de pyrrolidine utilises en tant qu'antagonistes des recepteurs muscariniques
WO2007007282A2 (fr) * 2005-07-11 2007-01-18 Ranbaxy Laboratories Limited Antagonistes des recepteurs muscariniques
WO2007034325A1 (fr) * 2005-09-21 2007-03-29 Pfizer Limited Derives de carboxamide en tant qu'antagonistes de recepteur muscarinique
KR20090107567A (ko) * 2007-02-09 2009-10-13 아스텔라스세이야쿠 가부시키가이샤 아자 가교환 화합물
UA100983C2 (ru) 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
KR101341693B1 (ko) 2011-03-16 2013-12-16 동아에스티 주식회사 생약추출물을 함유하는 퇴행성 신경질환의 치료 및 예방을 위한 조성물
KR101341692B1 (ko) 2011-03-16 2013-12-20 동아에스티 주식회사 복합생약추출물을 함유하는 당뇨병성 말초 신경병증의 치료 및 예방을 위한 조성물
KR101457789B1 (ko) 2013-02-13 2014-11-03 동아제약 주식회사 상처 치료용 필름형성 약제학적 조성물 및 그의 제조방법

Also Published As

Publication number Publication date
HK1218755A1 (zh) 2017-03-10
JP6109425B2 (ja) 2017-04-05
PT3029026T (pt) 2019-02-06
PH12016500197A1 (en) 2016-05-02
CN105555761A (zh) 2016-05-04
ZA201601227B (en) 2017-11-29
PH12016500197B1 (en) 2016-05-02
TR201901449T4 (tr) 2019-02-21
CN105555761B (zh) 2018-12-11
CA2919624C (fr) 2018-07-24
KR20150014673A (ko) 2015-02-09
MY175411A (en) 2020-06-24
KR101538846B1 (ko) 2015-07-22
IL243830A0 (en) 2016-04-21
JP2016525571A (ja) 2016-08-25
RU2016106977A (ru) 2017-09-01
AU2014297144B2 (en) 2017-06-08
CA2919624A1 (fr) 2015-02-05
IL243830B (en) 2019-07-31
SG11201600624RA (en) 2016-03-30
ES2710389T3 (es) 2019-04-24
AU2014297144A1 (en) 2016-03-03
WO2015016511A1 (fr) 2015-02-05
EP3029026A4 (fr) 2017-01-11
MX2016001200A (es) 2016-08-17
BR112016001746A8 (pt) 2020-01-21
UA116480C2 (uk) 2018-03-26
US9828339B2 (en) 2017-11-28
US20160176816A1 (en) 2016-06-23
RU2644234C2 (ru) 2018-02-09
EP3029026A1 (fr) 2016-06-08
EP3029026B1 (fr) 2018-12-05
BR112016001746A2 (pt) 2017-08-01

Similar Documents

Publication Publication Date Title
IN2012DN02968A (fr)
NZ595307A (en) Atropisomers of 2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
MX2017011951A (es) Derivados sustituidos de indol 3 novedosos, composiciones farmaceuticas y metodos para uso.
PH12018500533A1 (en) Pyrazolyl-substituted heteroaryls and their use as medicaments
HRP20241145T1 (hr) Biciklički aza spojevi kao agonisti muskarinskih receptora
WO2011051490A3 (fr) Dérivés hétérocycliques
TW201144302A (en) 2,5,6,7-tetrahydro-[1,4]oxazepin-3-ylamine or 2,3,6,7-tetrahydro-[1,4]oxazepin-5-ylamine compounds
WO2011110876A8 (fr) Nouveaux sels pour fabrication de compositions pharmaceutiques
MY143483A (en) Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders
PE20141167A1 (es) Piridopirazinas sustituidas como inhibidores novedosos de ptk
MX351305B (es) Antagonistas del receptor de mineralocorticoides.
HK1207860A1 (en) 2-phenyl-5-heterocyclyl-tetrahydro-2h-pyran-3-amine compounds for use in the treatment of diabetes and its associated disorders
CL2008000119A1 (es) Compuestos derivados de pirazol, antagonistas del receptor nicotinico de acetilcolina; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como demencia senil, alzheimer y esquizofrenia.
MX2013008056A (es) 1,4-oxazepinas como inhibidores de beta-secretasa 1 (bace1) y/o beta-secretasa 2 (bace2).
JOP20130213B1 (ar) معارضات لمستقبلht3-5
MX353209B (es) Antagonistas d2, metodos de sintesis y metodos de uso.
IN2014MN01756A (fr)
TW201613890A (en) Pyridine derivatives as muscarinic M1 receptor positive allosteric modulators
MX350862B (es) Acidos de piperidinil naftilacetico.
WO2010084402A3 (fr) Composés hétérocycliques en tant qu'inhibiteurs de phosphodiestérase
MX2016008536A (es) Derivados de fluoro-naftilo.
ATE531692T1 (de) Als antagonisten am muskarinrezeptor geeignete guanidinhaltige verbindungen
PH12016500197A1 (en) Novel biphenyl derivative and method for preparing same
WO2014014794A3 (fr) Antagonistes des récepteurs aux minéralocorticoïdes
SI2532651T1 (sl) Postopek sinteze in kristalinična oblika 4-(3-(cis-heksahidrociklopenta(c)pirol-2(1H)-il)propoksi) benzamid hidroklorida ter njegova prosta baza, pa tudi farmacevtski sestavki, ki ju vsebujejo

Legal Events

Date Code Title Description
FG Grant or registration