MX9600765A - Proteina y metodos para producir la proteina. - Google Patents
Proteina y metodos para producir la proteina.Info
- Publication number
- MX9600765A MX9600765A MX9600765A MX9600765A MX9600765A MX 9600765 A MX9600765 A MX 9600765A MX 9600765 A MX9600765 A MX 9600765A MX 9600765 A MX9600765 A MX 9600765A MX 9600765 A MX9600765 A MX 9600765A
- Authority
- MX
- Mexico
- Prior art keywords
- protein
- amino acid
- reduction
- acid sequence
- sequence represented
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Una proteína derivada de fibroblasto humano, con secuencia de aminoácidos N-terminal representada en las Secuencias Numero 1 y 2, con un peso molecular de ca. 15 kD bajo condiciones de reduccion y no reduccion mediante (electroforesis de gel poliacrilamida - sulfato dodecil de sodio), y con una actividad para estimular el crecimiento de osteoblastos. La proteína que contiene la secuencia de aminoácidos representada en la Secuencia Numero 9 y que tiene actividad de crecimiento de osteoblastos. Un método para preparar la proteína mediante el cultivo de fibroblasto humano y tratar el medio condicionado para purificacion. La proteína se produce mediante procedimiento de ingeniería genética. La proteína se utiliza para el tratamiento de padecimientos con reduccion de masa osea tales como la osteoporosis, o se utiliza como antígeno para diagnostico inmunologico de las enfermedades.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6-168984 | 1994-06-27 | ||
| JP16898494 | 1994-06-27 | ||
| JP168984/1994 | 1994-06-27 | ||
| PCT/JP1995/001270 WO1996000240A1 (en) | 1994-06-27 | 1995-06-26 | Novel protein and process for producing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9600765A true MX9600765A (es) | 1997-07-31 |
| MXPA96000765A MXPA96000765A (es) | 1997-12-01 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| HUT76748A (en) | 1997-11-28 |
| AU2753595A (en) | 1996-01-19 |
| WO1996000240A1 (en) | 1996-01-04 |
| NO960766L (no) | 1996-04-24 |
| FI960706L (fi) | 1996-04-12 |
| US6046033A (en) | 2000-04-04 |
| FI960706A7 (fi) | 1996-04-12 |
| IL114356A0 (en) | 1995-10-31 |
| KR960703943A (ko) | 1996-08-31 |
| HU220130B (hu) | 2001-11-28 |
| CN1129944A (zh) | 1996-08-28 |
| CA2169953A1 (en) | 1996-01-04 |
| ZA955319B (en) | 1996-12-27 |
| EP0725080A1 (en) | 1996-08-07 |
| NZ288352A (en) | 1997-12-19 |
| NO960766D0 (no) | 1996-02-26 |
| HU9600395D0 (en) | 1996-04-29 |
| FI960706A0 (fi) | 1996-02-16 |
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