MY101940A - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
MY101940A
MY101940A MYPI87002761A MYPI19872761A MY101940A MY 101940 A MY101940 A MY 101940A MY PI87002761 A MYPI87002761 A MY PI87002761A MY PI19872761 A MYPI19872761 A MY PI19872761A MY 101940 A MY101940 A MY 101940A
Authority
MY
Malaysia
Prior art keywords
formula
chemical compounds
relates
compounds
quaternaryammonio
Prior art date
Application number
MYPI87002761A
Inventor
Naito Takayuki
Okumura Jun
Oka Masahisa
Uamashita Haruhiro
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MY101940A publication Critical patent/MY101940A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

THIS APPLICATION RELATES TO 7-<2-(5-AMINO-1,2,4-THIADIAZOL-3-Y1)-2 SUBSTITUTED)IMINOACETAMIDO]-3-[3-(QUATERNARYAMMONIO)-1-PROPEN-1-Y1]-3- CEPHEM--4-CARBOXYLATES OF THE FORMULA(FORMULA 1)IN WHICH R1 AND R2 ARE AS DEFINED HEREIN AND -ON = Q IS QUATERNARY AMMONIO GROUP AS DEFINED HEREIN, AND TO SALTS AND ESTERS THEREOF.THIS INVENTION ALSO RELATES TO PROCESSES FOR THE PREPARATION OF THE COMPOUNDS OF FORMULA 1 AND PHARMACEUTICAL COMPOSITIONS CONTAINING AT LEAST ONE COMPOUND OF FORMULA 1.
MYPI87002761A 1984-04-09 1987-10-01 Chemical compounds MY101940A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59794184A 1984-04-09 1984-04-09

Publications (1)

Publication Number Publication Date
MY101940A true MY101940A (en) 1992-02-15

Family

ID=24393575

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI87002761A MY101940A (en) 1984-04-09 1987-10-01 Chemical compounds

Country Status (31)

Country Link
JP (4) JPS615084A (en)
KR (1) KR870002166B1 (en)
AR (1) AR244694A1 (en)
AT (1) AT388735B (en)
AU (2) AU580990B2 (en)
BE (1) BE902148A (en)
CA (3) CA1276929C (en)
CH (1) CH669197A5 (en)
DD (3) DD249024A5 (en)
DE (1) DE3512225A1 (en)
DK (1) DK155985A (en)
ES (4) ES8607318A1 (en)
FI (1) FI84830C (en)
FR (1) FR2563832B1 (en)
GB (3) GB2157293B (en)
GR (1) GR850883B (en)
HU (2) HU193750B (en)
IE (2) IE58408B1 (en)
IL (1) IL74826A (en)
IT (1) IT1190353B (en)
LU (1) LU85840A1 (en)
MY (1) MY101940A (en)
NL (1) NL192925C (en)
NZ (1) NZ211659A (en)
OA (1) OA07985A (en)
PT (1) PT80246B (en)
RU (1) RU2056425C1 (en)
SE (4) SE466205B (en)
SU (4) SU1436882A3 (en)
YU (2) YU46151B (en)
ZA (1) ZA852236B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61145186A (en) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd Novel cephem compound and preparation thereof
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
WO1987003875A1 (en) * 1985-12-26 1987-07-02 Eisai Co., Ltd. Cephalosporin derivatives
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
AU614723B2 (en) * 1986-10-13 1991-09-12 Eisai Co. Ltd. 3-propenylcephem derivative
JPH085897B2 (en) * 1986-11-06 1996-01-24 エーザイ株式会社 3-propenyl cephem derivative
FR2622585B1 (en) * 1987-11-03 1991-04-19 Roussel Uclaf NOVEL CEPHALOSPORINS COMPRISING IN POSITION 3 A SUBSTITUTED VINYL RADICAL, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS, THE COMPOSITIONS CONTAINING THEM AND THE NEW INTERMEDIATES OBTAINED
JPH0699449B2 (en) * 1988-03-16 1994-12-07 エーザイ株式会社 Synthetic intermediate of cephem derivative
EP0612751A3 (en) * 1988-03-16 1994-09-21 Eisai Co Ltd Compounds for the preparation of cephem derivatives.
FR2655042B1 (en) * 1989-11-29 1994-01-21 Adir Cie NOVEL SUBSTITUTED BENZOTHIAZOLINONES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2663332B1 (en) * 1990-06-15 1997-11-07 Roussel Uclaf NOVEL CEPHALOSPORINS COMPRISING IN POSITION 3 A RADICAL PROPENYL SUBSTITUTED BY A QUATERNARY AMMONIUM, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS, THE COMPOSITIONS CONTAINING THEM AND THE NEW INTERMEDIATES OBTAINED.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (en) * 1991-08-21 1993-06-25 Biochemie Gmbh NEW PROCESS AND NEW INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVES
JPH0741484A (en) * 1993-07-29 1995-02-10 Katayama Seiyakushiyo:Kk Cephem compound and antibacterial agent
EP0723966A4 (en) * 1994-08-16 1997-01-29 Meiji Seika Co Novel cephem derivative
CA2335288A1 (en) 1998-06-22 1999-12-29 F. Hoffmann-La Roche Ag Propenyl cephalosporin derivatives
WO2005026176A1 (en) 2003-09-09 2005-03-24 Nippon Chemical Industrial Co.,Ltd. Process for producing 3-chloromethyl-3-cephem derivative

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
EP0025017A1 (en) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (en) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
GR78245B (en) * 1980-09-12 1984-09-26 Ciba Geigy Ag
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives

Also Published As

Publication number Publication date
GB2194789B (en) 1988-10-12
YU46151B (en) 1993-05-28
KR850007424A (en) 1985-12-04
JPH0351716B2 (en) 1991-08-07
SU1436882A3 (en) 1988-11-07
DK155985D0 (en) 1985-04-03
ES542013A0 (en) 1986-06-16
DD236735A5 (en) 1986-06-18
HUT37622A (en) 1986-01-23
OA07985A (en) 1987-01-31
ATA103985A (en) 1989-01-15
IE850866L (en) 1985-10-09
JPS61143390A (en) 1986-07-01
JPH0350754B2 (en) 1991-08-02
HU204277B (en) 1991-12-30
AU580990B2 (en) 1989-02-09
PT80246B (en) 1987-10-20
GB2157293B (en) 1988-10-05
JPS615084A (en) 1986-01-10
RU2056425C1 (en) 1996-03-20
ES551550A0 (en) 1987-06-01
GB2194789A (en) 1988-03-16
IL74826A (en) 1990-01-18
PT80246A (en) 1985-05-01
LU85840A1 (en) 1985-12-16
SE8901225L (en) 1989-04-06
DK155985A (en) 1985-10-10
DD249024A5 (en) 1987-08-26
GB2194790B (en) 1988-10-05
ZA852236B (en) 1985-11-27
CH669197A5 (en) 1989-02-28
FI84830B (en) 1991-10-15
ES8706694A1 (en) 1987-07-01
SE8901224L (en) 1989-04-06
AT388735B (en) 1989-08-25
YU46213B (en) 1993-05-28
ES557060A0 (en) 1987-12-01
SU1487814A3 (en) 1989-06-15
ES8607318A1 (en) 1986-06-16
DD251752A5 (en) 1987-11-25
JPH0357106B2 (en) 1991-08-30
JPS61143387A (en) 1986-07-01
AU2504188A (en) 1989-03-02
NL192925C (en) 1998-05-07
ES8706155A1 (en) 1987-06-01
NZ211659A (en) 1988-11-29
YU118987A (en) 1988-10-31
SE505256C2 (en) 1997-07-21
JPS61143391A (en) 1986-07-01
SU1375140A3 (en) 1988-02-15
KR870002166B1 (en) 1987-12-14
CA1340672C (en) 1999-07-20
GB8508846D0 (en) 1985-05-09
GB2194790A (en) 1988-03-16
GR850883B (en) 1985-11-25
SE8901226D0 (en) 1989-04-06
IT8520267A0 (en) 1985-04-05
JPH0262557B2 (en) 1990-12-26
CA1276929C (en) 1990-11-27
SE8501680D0 (en) 1985-04-03
IL74826A0 (en) 1985-07-31
SE8901225D0 (en) 1989-04-06
NL8501002A (en) 1985-11-01
AU4086285A (en) 1985-10-17
FR2563832A1 (en) 1985-11-08
SE8501680L (en) 1985-10-10
SE8901226L (en) 1989-04-06
SE466205B (en) 1992-01-13
FI851379L (en) 1985-10-10
SE8901224D0 (en) 1989-04-06
AR244694A1 (en) 1993-11-30
ES551551A0 (en) 1987-07-01
SU1367858A3 (en) 1988-01-15
FI851379A0 (en) 1985-04-04
GB8721346D0 (en) 1987-10-14
ES8800949A1 (en) 1987-12-01
CA1340638C (en) 1999-07-06
NL192925B (en) 1998-01-05
IE58403B1 (en) 1993-09-22
DE3512225A1 (en) 1985-10-17
GB2157293A (en) 1985-10-23
SE470259B (en) 1993-12-20
FI84830C (en) 1992-01-27
YU60085A (en) 1987-12-31
HU193750B (en) 1987-11-30
IT1190353B (en) 1988-02-16
AU610278B2 (en) 1991-05-16
BE902148A (en) 1985-10-09
IE58408B1 (en) 1993-09-22
FR2563832B1 (en) 1989-08-18
GB8721347D0 (en) 1987-10-14
SE470260B (en) 1993-12-20
DE3512225C2 (en) 1990-02-22

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