MY122105A - Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids. - Google Patents
Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids.Info
- Publication number
- MY122105A MY122105A MYPI98004606A MYPI9804606A MY122105A MY 122105 A MY122105 A MY 122105A MY PI98004606 A MYPI98004606 A MY PI98004606A MY PI9804606 A MYPI9804606 A MY PI9804606A MY 122105 A MY122105 A MY 122105A
- Authority
- MY
- Malaysia
- Prior art keywords
- phenyl
- preparing substituted
- group
- cyanocyclohexanoic
- acids
- Prior art date
Links
- XWFKZQVEYDVFTA-UHFFFAOYSA-N 4-cyano-4-phenylcyclohexane-1-carboxylic acid Chemical class C1CC(C(=O)O)CCC1(C#N)C1=CC=CC=C1 XWFKZQVEYDVFTA-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 CARBOXYL GROUP Chemical group 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6161397P | 1997-10-10 | 1997-10-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY122105A true MY122105A (en) | 2006-03-31 |
Family
ID=22036929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI98004606A MY122105A (en) | 1997-10-10 | 1998-10-08 | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids. |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1043930A4 (id) |
| JP (1) | JP2001519363A (id) |
| KR (1) | KR100560038B1 (id) |
| CN (1) | CN1192025C (id) |
| AP (1) | AP1335A (id) |
| AR (1) | AR015952A1 (id) |
| AU (1) | AU741832B2 (id) |
| BG (1) | BG104302A (id) |
| BR (1) | BR9814064A (id) |
| CA (1) | CA2305614A1 (id) |
| DZ (1) | DZ2619A1 (id) |
| EA (1) | EA003609B1 (id) |
| HU (1) | HUP0003905A3 (id) |
| ID (1) | ID25536A (id) |
| IL (1) | IL135434A (id) |
| MA (1) | MA24670A1 (id) |
| MY (1) | MY122105A (id) |
| NO (1) | NO20001777L (id) |
| NZ (1) | NZ503759A (id) |
| OA (1) | OA11347A (id) |
| PE (1) | PE121599A1 (id) |
| PL (1) | PL191974B1 (id) |
| SA (1) | SA99191000A (id) |
| SK (1) | SK4902000A3 (id) |
| TR (1) | TR200000945T2 (id) |
| TW (1) | TW440557B (id) |
| UA (1) | UA67753C2 (id) |
| UY (2) | UY25201A1 (id) |
| WO (1) | WO1999018793A1 (id) |
| ZA (1) | ZA989228B (id) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9920152D0 (en) * | 1999-08-25 | 1999-10-27 | Smithkline Beecham Plc | Novel process |
| EP1237851A4 (en) * | 1999-12-15 | 2004-06-23 | Smithkline Beecham | SALES OF I CIS / I-4-CYANO-4-3- (CYCLOPENTYLOXY) -4-METHOXYPHENYL] CYCLHEXAN-1-CARBONIC ACID |
| AP1432A (en) * | 2000-01-26 | 2005-06-20 | Smithkline Beecham Corp | Monohydrate of Cis-Lithium-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylate. |
| CA2402384A1 (en) | 2000-03-16 | 2001-09-20 | Inflazyme Pharmaceuticals Ltd. | Benzylated pde4 inhibitors |
| ES2248231T3 (es) | 2001-01-31 | 2006-03-16 | Pfizer Products Inc. | Derivados de eteres utiles como inhibidores de las isozimas pde4. |
| US7250518B2 (en) | 2001-01-31 | 2007-07-31 | Pfizer Inc. | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes |
| EE200300360A (et) | 2001-01-31 | 2003-12-15 | Pfizer Products Inc. | PDE4 isosüümide inhibiitoritena kasutatavad nikotiinamiidi biarüülderivaadid |
| CN1489588A (zh) | 2001-01-31 | 2004-04-14 | �Ʒ� | 用作pde4同功酶抑制剂的噻唑基,噁唑基,吡咯基,和咪唑基羧酸酰胺衍生物 |
| CN102491959B (zh) * | 2011-12-19 | 2015-03-25 | 江苏澄扬作物科技有限公司 | 一种环氧乙烷衍生物的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4021478A (en) * | 1972-07-13 | 1977-05-03 | The Upjohn Company | Preparation of carboxylic acids from glycidonitriles with ionic lewis acids |
| US5552438A (en) * | 1992-04-02 | 1996-09-03 | Smithkline Beecham Corporation | Compounds useful for treating allergic and inflammatory diseases |
| US5524438A (en) * | 1994-12-15 | 1996-06-11 | United Technologies Corporation | Segmented bulkhead liner for a gas turbine combustor |
| MY118813A (en) * | 1997-02-12 | 2005-01-31 | Smithkline Beecham Corp | Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids |
| US6452022B1 (en) * | 1997-10-10 | 2002-09-17 | Smithkline Beecham Corporation | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids |
-
1998
- 1998-07-10 UA UA2000041944A patent/UA67753C2/uk unknown
- 1998-10-02 MA MA25278A patent/MA24670A1/fr unknown
- 1998-10-07 WO PCT/US1998/021061 patent/WO1999018793A1/en not_active Ceased
- 1998-10-07 CN CNB988100304A patent/CN1192025C/zh not_active Expired - Fee Related
- 1998-10-07 NZ NZ503759A patent/NZ503759A/en unknown
- 1998-10-07 EP EP98950965A patent/EP1043930A4/en not_active Withdrawn
- 1998-10-07 EA EA200000406A patent/EA003609B1/ru not_active IP Right Cessation
- 1998-10-07 ID IDW20000614A patent/ID25536A/id unknown
- 1998-10-07 HU HU0003905A patent/HUP0003905A3/hu not_active Application Discontinuation
- 1998-10-07 TR TR2000/00945T patent/TR200000945T2/xx unknown
- 1998-10-07 KR KR1020007003742A patent/KR100560038B1/ko not_active Expired - Fee Related
- 1998-10-07 CA CA002305614A patent/CA2305614A1/en not_active Abandoned
- 1998-10-07 UY UY25201A patent/UY25201A1/es not_active IP Right Cessation
- 1998-10-07 SK SK490-2000A patent/SK4902000A3/sk unknown
- 1998-10-07 AU AU96874/98A patent/AU741832B2/en not_active Ceased
- 1998-10-07 DZ DZ980229A patent/DZ2619A1/xx active
- 1998-10-07 AP APAP/P/2000/001782A patent/AP1335A/en active
- 1998-10-07 JP JP2000515437A patent/JP2001519363A/ja active Pending
- 1998-10-07 BR BR9814064-7A patent/BR9814064A/pt not_active IP Right Cessation
- 1998-10-07 PL PL339759A patent/PL191974B1/pl not_active IP Right Cessation
- 1998-10-07 AR ARP980105002A patent/AR015952A1/es unknown
- 1998-10-07 IL IL13543498A patent/IL135434A/en not_active IP Right Cessation
- 1998-10-08 MY MYPI98004606A patent/MY122105A/en unknown
- 1998-10-09 ZA ZA989228A patent/ZA989228B/xx unknown
- 1998-10-09 PE PE1998000955A patent/PE121599A1/es not_active Application Discontinuation
- 1998-12-01 TW TW087116680A patent/TW440557B/zh not_active IP Right Cessation
-
1999
- 1999-01-26 SA SA99191000A patent/SA99191000A/ar unknown
- 1999-05-25 UY UY25524A patent/UY25524A1/es not_active Application Discontinuation
-
2000
- 2000-04-05 BG BG104302A patent/BG104302A/xx unknown
- 2000-04-06 NO NO20001777A patent/NO20001777L/no not_active Application Discontinuation
- 2000-04-07 OA OA1200000100A patent/OA11347A/en unknown
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