MY132777A - Inhalable formulation of a solution containing a tiotropium salt - Google Patents

Inhalable formulation of a solution containing a tiotropium salt

Info

Publication number: MY132777A
Authority: MY; Malaysia
Prior art keywords: solution containing; inhalable formulation; tiotropium salt; propellant; water
Prior art date: 2000-10-31

Application number

MYPI20014987A

Other languages

English (en)

Inventor

Karin Drechsel Dr

Barbara Niklaus-Humke Dr

Christel Schmelzer Dr

Barth Petra

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-31

Filing date

2001-10-29

Publication date

2007-10-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7661727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY132777(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-10-29 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2007-10-31 Publication of MY132777A publication Critical patent/MY132777A/en

Links

239000000203 mixture Substances 0.000 title abstract 3
238000009472 formulation Methods 0.000 title abstract 2
LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical class O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 title 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
239000003380 propellant Substances 0.000 abstract 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
LERNTVKEWCAPOY-VOGVJGKGSA-N C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 Chemical compound C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 LERNTVKEWCAPOY-VOGVJGKGSA-N 0.000 abstract 1
239000000443 aerosol Substances 0.000 abstract 1
229960000257 tiotropium bromide Drugs 0.000 abstract 1
MQLXPRBEAHBZTK-SEINRUQRSA-M tiotropium bromide hydrate Chemical compound O.[Br-].C[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 MQLXPRBEAHBZTK-SEINRUQRSA-M 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Emergency Medicine (AREA)
Dispersion Chemistry (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

MYPI20014987A 2000-10-31 2001-10-29 Inhalable formulation of a solution containing a tiotropium salt MY132777A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10054042		2000-10-31

Publications (1)

Publication Number	Publication Date
MY132777A true MY132777A (en)	2007-10-31

Family

ID=7661727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MYPI20014987A MY132777A (en)	2000-10-31	2001-10-29	Inhalable formulation of a solution containing a tiotropium salt

Country Status (32)

Country	Link
EP (1)	EP1335729A2 (de)
JP (1)	JP4559703B2 (de)
KR (1)	KR100983208B1 (de)
CN (1)	CN1237970C (de)
AR (1)	AR038765A1 (de)
AU (2)	AU2002221741B2 (de)
BG (1)	BG66425B1 (de)
BR (1)	BR0115016A (de)
CA (1)	CA2427583C (de)
CZ (1)	CZ305033B6 (de)
DE (1)	DE10152369A1 (de)
EA (1)	EA009068B1 (de)
EC (1)	ECSP034570A (de)
EE (1)	EE05343B1 (de)
HR (1)	HRP20030337A2 (de)
HU (1)	HUP0301377A3 (de)
IL (2)	IL155676A0 (de)
ME (1)	ME00242B (de)
MX (1)	MXPA03003750A (de)
MY (1)	MY132777A (de)
NO (1)	NO332524B1 (de)
NZ (1)	NZ526024A (de)
PE (1)	PE20020518A1 (de)
PL (1)	PL361001A1 (de)
SA (1)	SA01220503B1 (de)
SK (1)	SK288031B6 (de)
TW (1)	TWI296934B (de)
UA (1)	UA76435C2 (de)
UY (1)	UY26991A1 (de)
WO (1)	WO2002036591A2 (de)
YU (1)	YU33103A (de)
ZA (1)	ZA200303045B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001083800A2 (en)	2000-04-28	2001-11-08	Kosan Biosciences, Inc.	Heterologous production of polyketides
US20030235538A1 (en)	2002-04-09	2003-12-25	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Method for the administration of an anticholinergic by inhalation
GB2389530B (en)	2002-06-14	2007-01-10	Cipla Ltd	Pharmaceutical compositions
CA2544611A1 (en) *	2003-10-09	2005-04-21	Inverseon, Inc.	Method of treating airway diseases with beta-adrenergic inverse agonists
SE0303269L (sv) *	2003-12-03	2005-06-04	Microdrug Ag	Medicinsk produkt
SI1863476T1 (sl) *	2005-03-16	2016-05-31	Meda Pharma Gmbh & Co. Kg	Kombinacija antiholinergikov in antagonistov receptorja levkotriena za zdravljenje respiratornih bolezni
AU2007267523B2 (en) *	2006-05-26	2012-02-09	Dey, L.P.	Nebulizable compositions of quaternary ammonium muscarinic receptor antagonists
CN100446770C (zh) *	2007-01-10	2008-12-31	上海现代药物制剂工程研究中心有限公司	丙酸培氯米松水雾剂
TR200907237A2 (tr) *	2009-09-23	2011-04-21	B�Lg�� Mahmut	Tiotropyum kuru toz kombinasyonu
CN111936124A (zh) *	2018-07-26	2020-11-13	四川海思科制药有限公司	一种含格隆铵盐及茚达特罗盐的气雾剂药物组合物及其制备方法与应用
CN116196298A (zh) *	2018-07-26	2023-06-02	四川海思科制药有限公司	一种含格隆铵盐的气雾剂药物组合物及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0504112A3 (en) *	1991-03-14	1993-04-21	Ciba-Geigy Ag	Pharmaceutical aerosol formulations
DE4203306A1 (de) *	1992-02-06	1993-08-12	Ig Spruehtechnik Gmbh	Asthma oder pulmonal-aerosolzubereitungen mit lecithin
BR9609307B1 (pt) *	1995-06-27	2010-03-09		preparação farmacêutica para produção de aerossóis inaláveis isentos de propelentes para administração nos pulmões, bem como aerossol compreendendo a mesma.
US5824669A (en) *	1996-03-22	1998-10-20	Nitromed, Inc.	Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
CA2256721A1 (en) *	1996-06-04	1997-12-11	The Procter & Gamble Company	A nasal spray containing an intranasal steroid and an antihistamine
DE19653969A1 (de) *	1996-12-20	1998-06-25	Boehringer Ingelheim Kg	Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
JPH10298107A (ja) *	1997-04-25	1998-11-10	Taisho Pharmaceut Co Ltd	医薬組成物
ATE234604T1 (de) *	1998-08-04	2003-04-15	Jago Res Ag	Medizinische aerosolformulierungen
DE19847968A1 (de) *	1998-10-17	2000-04-20	Boehringer Ingelheim Pharma	Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen

2001
- 2001-10-24 YU YU33103A patent/YU33103A/sh unknown
- 2001-10-24 HU HU0301377A patent/HUP0301377A3/hu unknown
- 2001-10-24 AU AU2002221741A patent/AU2002221741B2/en not_active Expired
- 2001-10-24 EP EP01992710A patent/EP1335729A2/de not_active Ceased
- 2001-10-24 CN CNB018183271A patent/CN1237970C/zh not_active Expired - Lifetime
- 2001-10-24 IL IL15567601A patent/IL155676A0/xx unknown
- 2001-10-24 ME MEP-2008-407A patent/ME00242B/de unknown
- 2001-10-24 HR HR20030337A patent/HRP20030337A2/hr not_active Application Discontinuation
- 2001-10-24 DE DE10152369A patent/DE10152369A1/de not_active Withdrawn
- 2001-10-24 CZ CZ2003-1487A patent/CZ305033B6/cs not_active IP Right Cessation
- 2001-10-24 SK SK526-2003A patent/SK288031B6/sk not_active IP Right Cessation
- 2001-10-24 JP JP2002539350A patent/JP4559703B2/ja not_active Expired - Lifetime
- 2001-10-24 EE EEP200300202A patent/EE05343B1/xx unknown
- 2001-10-24 BR BR0115016-2A patent/BR0115016A/pt active Search and Examination
- 2001-10-24 EA EA200300483A patent/EA009068B1/ru not_active IP Right Cessation
- 2001-10-24 AU AU2174102A patent/AU2174102A/xx active Pending
- 2001-10-24 PL PL01361001A patent/PL361001A1/xx not_active Application Discontinuation
- 2001-10-24 WO PCT/EP2001/012296 patent/WO2002036591A2/de not_active Ceased
- 2001-10-24 KR KR1020037006001A patent/KR100983208B1/ko not_active Expired - Lifetime
- 2001-10-24 NZ NZ526024A patent/NZ526024A/en not_active IP Right Cessation
- 2001-10-24 CA CA002427583A patent/CA2427583C/en not_active Expired - Fee Related
- 2001-10-24 UA UA2003054960A patent/UA76435C2/uk unknown
- 2001-10-24 MX MXPA03003750A patent/MXPA03003750A/es active IP Right Grant
- 2001-10-29 UY UY26991A patent/UY26991A1/es not_active Application Discontinuation
- 2001-10-29 TW TW090126752A patent/TWI296934B/zh not_active IP Right Cessation
- 2001-10-29 MY MYPI20014987A patent/MY132777A/en unknown
- 2001-10-29 PE PE2001001072A patent/PE20020518A1/es active IP Right Grant
- 2001-10-31 AR ARP010105088A patent/AR038765A1/es not_active Application Discontinuation
- 2001-11-03 SA SA01220503A patent/SA01220503B1/ar unknown
2003
- 2003-04-16 BG BG107726A patent/BG66425B1/bg unknown
- 2003-04-17 ZA ZA200303045A patent/ZA200303045B/xx unknown
- 2003-04-28 EC EC2003004570A patent/ECSP034570A/es unknown
- 2003-04-29 NO NO20031914A patent/NO332524B1/no not_active IP Right Cessation
- 2003-04-30 IL IL155676A patent/IL155676A/en active IP Right Grant

Also Published As

Publication number	Publication date
AU2174102A (en)	2002-05-15
CN1237970C (zh)	2006-01-25
NO20031914D0 (no)	2003-04-29
UY26991A1 (es)	2002-06-20
EA009068B1 (ru)	2007-10-26
SK288031B6 (sk)	2012-12-03
YU33103A (sh)	2006-05-25
JP4559703B2 (ja)	2010-10-13
EE200300202A (et)	2003-10-15
CA2427583A1 (en)	2002-05-10
IL155676A0 (en)	2003-11-23
EA200300483A1 (ru)	2003-12-25
AR038765A1 (es)	2005-01-26
JP2004523482A (ja)	2004-08-05
WO2002036591A2 (de)	2002-05-10
CZ20031487A3 (cs)	2003-09-17
HRP20030337A2 (en)	2005-04-30
SK5262003A3 (en)	2003-10-07
ZA200303045B (en)	2004-04-22
PE20020518A1 (es)	2002-07-12
HUP0301377A2 (hu)	2003-10-28
MEP40708A (en)	2011-02-10
BR0115016A (pt)	2005-05-03
AU2002221741B2 (en)	2007-04-05
NO20031914L (no)	2003-06-23
ME00242B (de)	2011-05-10
TWI296934B (en)	2008-05-21
BG66425B1 (bg)	2014-04-30
KR20040010552A (ko)	2004-01-31
IL155676A (en)	2012-05-31
EP1335729A2 (de)	2003-08-20
ECSP034570A (es)	2003-06-25
DE10152369A1 (de)	2002-05-08
MXPA03003750A (es)	2004-10-15
WO2002036591A3 (de)	2002-07-25
NO332524B1 (no)	2012-10-08
NZ526024A (en)	2005-10-28
CZ305033B6 (cs)	2015-04-08
SA01220503B1 (ar)	2007-03-10
BG107726A (bg)	2004-11-30
CA2427583C (en)	2008-02-12
KR100983208B1 (ko)	2010-09-20
CN1473044A (zh)	2004-02-04
PL361001A1 (en)	2004-09-20
EE05343B1 (et)	2010-10-15
HK1060569A1 (en)	2004-08-13
UA76435C2 (en)	2006-08-15
HUP0301377A3 (en)	2005-12-28

Publication	Publication Date	Title
AP1572A (en)	2006-02-13	Crystalline monohydrate, method for producing the same and use thereof in the production of a medicament.
HUP0400333A2 (hu)	2004-12-28	Kristályos antikolinergikum, eljárás előállítására és alkalmazása gyógyszerkészítmény előállítására
LT2001119A (en)	2002-07-25	Pharmaceutical formulations comprising intranasal morphine and use thereof
YU33103A (sh)	2006-05-25	Formulacija rastvora za inhalaciju sa soli tiotropijuma
SI2040703T1 (sl)	2010-02-26	Derivati 2-benzoil-imidazopiridinov, njihova priprava in njihova uporaba v terapevtiki
MY138940A (en)	2009-08-28	Inhalable formulation of a solution containing a tiotropium salt.
SE0102440D0 (sv)	2001-07-05	New compound
EA200501081A1 (ru)	2006-06-30	Производные тропенола - исходный материал для получения терапевтически эффективных соединений
MY137249A (en)	2009-01-30	Aerosol formulation for inhalation containing a tiotropium salt
ATE258046T1 (de)	2004-02-15	Pharmazeutische, metamizol enthaltende brauseformulierung
RU2003103757A (ru)	2004-08-20	Жидкая лекарственная форма налтрексона
DE68901852D1 (de)	1992-07-23	Primycin-loesungen.