MY133531A - Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds - Google Patents

Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds

Info

Publication number
MY133531A
MY133531A MYPI98002633A MYPI9802633A MY133531A MY 133531 A MY133531 A MY 133531A MY PI98002633 A MYPI98002633 A MY PI98002633A MY PI9802633 A MYPI9802633 A MY PI9802633A MY 133531 A MY133531 A MY 133531A
Authority
MY
Malaysia
Prior art keywords
formula
compound
synthesis
intermediates useful
tricyclic compounds
Prior art date
Application number
MYPI98002633A
Other languages
English (en)
Inventor
Xing Chen
Marc Poirier
Yee-Shing Wong
Guang-Zhong Wu
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MY133531A publication Critical patent/MY133531A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
MYPI98002633A 1997-06-16 1998-06-12 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds MY133531A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/882,753 US5760232A (en) 1997-06-16 1997-06-16 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds

Publications (1)

Publication Number Publication Date
MY133531A true MY133531A (en) 2007-11-30

Family

ID=25381267

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI98002633A MY133531A (en) 1997-06-16 1998-06-12 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds

Country Status (15)

Country Link
US (1) US5760232A (2)
EP (1) EP0991640B1 (2)
JP (1) JP3210023B2 (2)
AR (1) AR015886A1 (2)
AT (1) ATE214062T1 (2)
AU (1) AU8056898A (2)
CA (1) CA2293709C (2)
DE (1) DE69804100T2 (2)
DK (1) DK0991640T3 (2)
ES (1) ES2169917T3 (2)
IN (1) IN187755B (2)
MY (1) MY133531A (2)
PT (1) PT991640E (2)
WO (1) WO1998057958A1 (2)
ZA (1) ZA985207B (2)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998620A (en) * 1997-03-25 1999-12-07 Schering Corporation Synthesis of intermediates useful in preparing tricyclic compounds
WO2004031153A2 (en) * 2002-10-03 2004-04-15 Schering Corporation Enantioselective alkylation of tricyclic compounds
HK1203412A1 (en) 2011-12-28 2015-10-30 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
ES2643403T3 (es) 2011-12-28 2017-11-22 Global Blood Therapeutics, Inc. Compuestos de benzaldehído sustituidos y métodos para su uso en el aumento de la oxigenación tisular
CN105073728A (zh) 2013-03-15 2015-11-18 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
MX379235B (es) 2013-03-15 2025-03-11 Global Blood Therapeutics Inc Compuestos y sus usos para modular la hemoglobina.
WO2014150258A1 (en) 2013-03-15 2014-09-25 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
CN114181195A (zh) 2014-02-07 2022-03-15 全球血液疗法股份有限公司 一种化合物的结晶多晶型物
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
SG11201804647TA (en) 2015-12-04 2018-06-28 Global Blood Therapeutics Inc Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
TWI663160B (zh) 2016-05-12 2019-06-21 全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
US11014884B2 (en) 2018-10-01 2021-05-25 Global Blood Therapeutics, Inc. Modulators of hemoglobin
US12479816B2 (en) 2019-02-08 2025-11-25 University of Pittsburgh—of the Commonwealth System of Higher Education 20-HETE formation inhibitors
CN112341433A (zh) * 2020-11-16 2021-02-09 成都大学 一种氯雷他定的制备方法
AU2024286996A1 (en) * 2023-06-08 2026-01-08 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Preparation method for formamide compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
SG48750A1 (en) * 1993-10-15 1998-05-18 Schering Corp Tricyclic carbonate compounds useful for inhabition of g-protein function for treatment of proliferative diseases
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
SK86198A3 (en) * 1995-12-22 1999-02-11 Schering Corp Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases

Also Published As

Publication number Publication date
AR015886A1 (es) 2001-05-30
IN187755B (2) 2002-06-15
JP2000513032A (ja) 2000-10-03
ES2169917T3 (es) 2002-07-16
AU8056898A (en) 1999-01-04
CA2293709A1 (en) 1998-12-23
PT991640E (pt) 2002-07-31
DK0991640T3 (da) 2002-05-27
EP0991640B1 (en) 2002-03-06
ZA985207B (en) 1999-04-07
DE69804100T2 (de) 2002-10-31
JP3210023B2 (ja) 2001-09-17
WO1998057958A1 (en) 1998-12-23
ATE214062T1 (de) 2002-03-15
CA2293709C (en) 2004-02-10
US5760232A (en) 1998-06-02
EP0991640A1 (en) 2000-04-12
DE69804100D1 (de) 2002-04-11

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