MY185672A - Mono-or di-substituted indole derivatives as dengue viral replication inhibitors - Google Patents

Mono-or di-substituted indole derivatives as dengue viral replication inhibitors

Info

Publication number
MY185672A
MY185672A MYPI2017001601A MYPI2017001601A MY185672A MY 185672 A MY185672 A MY 185672A MY PI2017001601 A MYPI2017001601 A MY PI2017001601A MY PI2017001601 A MYPI2017001601 A MY PI2017001601A MY 185672 A MY185672 A MY 185672A
Authority
MY
Malaysia
Prior art keywords
dengue viral
mono
compounds
substituted indole
viral replication
Prior art date
Application number
MYPI2017001601A
Inventor
Dorothee Alice Marie-Eve Bardiot
Arnaud Didier M Marchand
Bart Rudolf Romanie Kesteleyn
Jean-Francois Bonfanti
Tim Hugo Maria Jonckers
Pierre Jean-Marie Bernard Raboisson
Original Assignee
Univ Leuven Kath
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leuven Kath, Janssen Pharmaceuticals Inc filed Critical Univ Leuven Kath
Priority claimed from PCT/EP2016/059975 external-priority patent/WO2016180696A1/en
Publication of MY185672A publication Critical patent/MY185672A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to mono- or di-substituted indole compounds, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.
MYPI2017001601A 2015-05-08 2016-05-04 Mono-or di-substituted indole derivatives as dengue viral replication inhibitors MY185672A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15166900 2015-05-08
PCT/EP2016/059975 WO2016180696A1 (en) 2015-05-08 2016-05-04 Mono- or di-substituted indole derivatives as dengue viral replication inhibitors

Publications (1)

Publication Number Publication Date
MY185672A true MY185672A (en) 2021-05-29

Family

ID=53059008

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2017001601A MY185672A (en) 2015-05-08 2016-05-04 Mono-or di-substituted indole derivatives as dengue viral replication inhibitors

Country Status (3)

Country Link
AR (2) AR104504A1 (en)
MA (1) MA43507B1 (en)
MY (1) MY185672A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114989131B (en) * 2022-05-30 2023-10-24 云南大学 N’-(2-(benzo[1,3]dioxolan-5-yl)acyl)aromatic hydrazide compounds and their synthesis and uses

Also Published As

Publication number Publication date
AR104504A1 (en) 2017-07-26
AR120158A2 (en) 2022-02-02
MA43507B1 (en) 2021-08-31

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