MY186959A - New effective aminoglycoside antibiotic for multidrug-resistant bacteria - Google Patents

New effective aminoglycoside antibiotic for multidrug-resistant bacteria

Info

Publication number
MY186959A
MY186959A MYPI2018700342A MYPI2018700342A MY186959A MY 186959 A MY186959 A MY 186959A MY PI2018700342 A MYPI2018700342 A MY PI2018700342A MY PI2018700342 A MYPI2018700342 A MY PI2018700342A MY 186959 A MY186959 A MY 186959A
Authority
MY
Malaysia
Prior art keywords
multidrug
resistant bacteria
new effective
aminoglycoside antibiotic
infectious diseases
Prior art date
Application number
MYPI2018700342A
Other languages
English (en)
Inventor
Takahashi Yoshiaki
Umemura Eijiro
Ida Takashi
Igarashi Masayuki
Original Assignee
Microbial Chem Res Found
Meiji Seika Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found, Meiji Seika Pharma Co Ltd filed Critical Microbial Chem Res Found
Publication of MY186959A publication Critical patent/MY186959A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MYPI2018700342A 2015-07-30 2016-07-29 New effective aminoglycoside antibiotic for multidrug-resistant bacteria MY186959A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015151250 2015-07-30
PCT/JP2016/072400 WO2017018528A1 (fr) 2015-07-30 2016-07-29 Nouvel antibiotique aminoglycosidique efficace contre les bactéries résistantes à plusieurs médicaments

Publications (1)

Publication Number Publication Date
MY186959A true MY186959A (en) 2021-08-26

Family

ID=57884581

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2018700342A MY186959A (en) 2015-07-30 2016-07-29 New effective aminoglycoside antibiotic for multidrug-resistant bacteria

Country Status (20)

Country Link
US (2) US10617704B2 (fr)
EP (2) EP3330275A4 (fr)
JP (1) JP6938376B2 (fr)
KR (1) KR102590696B1 (fr)
CN (1) CN108026133B (fr)
AR (1) AR105547A1 (fr)
AU (1) AU2016300993B2 (fr)
CL (1) CL2018000228A1 (fr)
CO (1) CO2018001237A2 (fr)
IL (1) IL257151B (fr)
MX (1) MX383996B (fr)
MY (1) MY186959A (fr)
PH (1) PH12018500202B1 (fr)
RU (1) RU2751634C2 (fr)
SA (1) SA518390825B1 (fr)
SG (2) SG10201913231RA (fr)
TW (1) TWI699372B (fr)
UA (1) UA123629C2 (fr)
WO (1) WO2017018528A1 (fr)
ZA (1) ZA201801312B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY186959A (en) * 2015-07-30 2021-08-26 Microbial Chem Res Found New effective aminoglycoside antibiotic for multidrug-resistant bacteria
JP2020055749A (ja) * 2017-01-27 2020-04-09 公益財団法人微生物化学研究会 多剤耐性菌に有効な新規アミノグリコシド抗生物質
US11485751B2 (en) 2017-05-01 2022-11-01 Wayne State University Apramycin derivatives
JP2021138615A (ja) * 2018-05-31 2021-09-16 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 多剤耐性菌に有効なアミノグリコシド抗生物質の製造方法
KR102811984B1 (ko) * 2021-08-04 2025-05-26 서울대학교산학협력단 신규 아미카신 유도체, 이의 제조방법, 및 이의 항균 용도
CN116462721B (zh) * 2023-04-18 2024-02-02 江南大学 抗菌性氨基糖苷衍生物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5782399A (en) * 1980-09-22 1982-05-22 Lilly Co Eli 2-deoxystreptamine aminoglycoside derivative and manufacture
US4468513A (en) 1980-09-22 1984-08-28 Eli Lilly And Company 2'-N-Acylated and 2'-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides
US4424345A (en) 1980-09-22 1984-01-03 Eli Lilly And Company 1-N-Acylated and 1-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process
JPS5782398A (en) * 1980-09-22 1982-05-22 Lilly Co Eli 2-deoxystreptamine aminoglycoside derivative
US4424344A (en) 1980-09-22 1984-01-03 Eli Lilly And Company 2-N-Acylated and 2-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process
JPS5772998A (en) * 1980-10-24 1982-05-07 Shionogi & Co Ltd Novel appamycin derivative
JPS5772999A (en) * 1980-10-24 1982-05-07 Shionogi & Co Ltd Novel 5-deoxyapramycin
US4385585A (en) * 1981-10-27 1983-05-31 Copco, Inc. Teakettle having whistle cap
US4379917A (en) * 1981-12-24 1983-04-12 Eli Lilly And Company 6"-(Substituted)-apramycin antibiotic derivatives and intermediates and starting materials therefor
US4360665A (en) * 1981-12-24 1982-11-23 Eli Lilly And Company 4"-N-(Substituted)-apramycin antibiotic derivatives and intermediates therefor
US4458065A (en) * 1983-02-17 1984-07-03 Eli Lilly And Company 7-N-(Substituted-apramycin antibiotic derivatives and intermediates therefor
EP2348027B1 (fr) 2006-04-07 2013-10-23 E. I. du Pont de Nemours and Company Lipochitooligosaccharides
UA97245C2 (en) * 2006-06-02 2012-01-25 Меиджи Сеика Фарма Ко., Лтд. Aminoglycoside antibiotics
EA017824B1 (ru) 2007-11-21 2013-03-29 Эйкеоджен, Инк. Антибактериальные аналоги аминогликозида
TWI472521B (zh) 2008-07-17 2015-02-11 Lexicon Pharmaceuticals Inc （２ｓ，３ｒ，４ｒ，５ｓ，６ｒ）－２－（４－氯－３－（４－乙氧苄基）苯基）－６－（甲硫）四氫－２ｈ－哌喃－３，４，５－三醇的固體形態與其使用方法
JP5922660B2 (ja) * 2010-09-13 2016-05-24 ユニバーシティ・オブ・チューリッヒＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｚｕｒｉｃｈ 細菌感染性疾患の処置
WO2013191550A1 (fr) * 2012-06-20 2013-12-27 Rijksuniversiteit Groningen Diazotation régiosélective des aminoglycosides
RU2491921C1 (ru) 2012-07-11 2013-09-10 Общество с ограниченной ответственностью "Опытно-технологическая фирма "Этрис" Способ лечения мастита у коров в сухостойный период
MY186959A (en) * 2015-07-30 2021-08-26 Microbial Chem Res Found New effective aminoglycoside antibiotic for multidrug-resistant bacteria

Also Published As

Publication number Publication date
UA123629C2 (uk) 2021-05-05
US11135234B2 (en) 2021-10-05
SG10201913231RA (en) 2020-03-30
WO2017018528A1 (fr) 2017-02-02
IL257151B (en) 2021-01-31
BR112018001849A2 (pt) 2018-09-18
AR105547A1 (es) 2017-10-11
ZA201801312B (en) 2019-07-31
RU2018107150A3 (fr) 2019-12-27
RU2751634C2 (ru) 2021-07-15
US20200155582A1 (en) 2020-05-21
KR20180043791A (ko) 2018-04-30
SA518390825B1 (ar) 2021-06-01
CN108026133A (zh) 2018-05-11
EP3330275A4 (fr) 2018-12-05
AU2016300993A1 (en) 2018-02-15
US10617704B2 (en) 2020-04-14
CL2018000228A1 (es) 2018-08-24
US20180214470A1 (en) 2018-08-02
NZ740037A (en) 2024-08-30
MX383996B (es) 2025-03-14
CN108026133B (zh) 2021-05-07
PH12018500202B1 (en) 2022-02-18
CA2993425A1 (fr) 2017-02-02
HK1254239A1 (zh) 2019-07-12
MX2018001022A (es) 2018-05-17
JPWO2017018528A1 (ja) 2018-05-17
SG11201800510WA (en) 2018-02-27
EP3330275A1 (fr) 2018-06-06
EP3498723A1 (fr) 2019-06-19
JP6938376B2 (ja) 2021-09-22
RU2018107150A (ru) 2019-08-29
IL257151A (en) 2018-03-29
TWI699372B (zh) 2020-07-21
KR102590696B1 (ko) 2023-10-18
PH12018500202A1 (en) 2018-07-30
CO2018001237A2 (es) 2018-05-10
AU2016300993B2 (en) 2020-07-02
TW201718616A (zh) 2017-06-01

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