MY8500351A - Pyridine derivatives as anti-inflammatory and immuno-regulatory agents - Google Patents

Pyridine derivatives as anti-inflammatory and immuno-regulatory agents

Info

Publication number: MY8500351A
Authority: MY; Malaysia
Prior art keywords: immuno; inflammatory; pyridine derivatives; regulatory agents; regulatory
Prior art date: 1981-06-26

Application number

MY351/85A

Other languages

English (en)

Inventor

Joseph George Lombardino

Charles Armon Harbert

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-06-26

Filing date

1985-12-30

Publication date

1985-12-31

1985-12-30 Application filed by Pfizer filed Critical Pfizer

1985-12-31 Publication of MY8500351A publication Critical patent/MY8500351A/xx

Links

230000003110 anti-inflammatory effect Effects 0.000 title 1
239000003795 chemical substances by application Substances 0.000 title 1
230000004957 immunoregulator effect Effects 0.000 title 1
150000003222 pyridines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

MY351/85A 1981-06-26 1985-12-30 Pyridine derivatives as anti-inflammatory and immuno-regulatory agents MY8500351A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/276,242 US4371696A (en)	1980-07-14	1981-06-26	Certain pyridine methylthio acetaldehyde derivatives and non-cyclic and cyclic acetals thereof

Publications (1)

Publication Number	Publication Date
MY8500351A true MY8500351A (en)	1985-12-31

Family

ID=23055809

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MY351/85A MY8500351A (en)	1981-06-26	1985-12-30	Pyridine derivatives as anti-inflammatory and immuno-regulatory agents

Country Status (22)

Country	Link
US (1)	US4371696A (fr)
JP (1)	JPS58916A (fr)
AU (1)	AU528433B2 (fr)
BE (1)	BE890374R (fr)
CH (1)	CH648483A5 (fr)
DE (1)	DE3215648A1 (fr)
FR (1)	FR2508904B2 (fr)
GB (1)	GB2100600B (fr)
GR (1)	GR75753B (fr)
HK (1)	HK67087A (fr)
IE (1)	IE51727B1 (fr)
IL (1)	IL63699A0 (fr)
IT (1)	IT1200569B (fr)
KE (1)	KE3458A (fr)
LU (1)	LU83827A1 (fr)
MY (1)	MY8500351A (fr)
NL (1)	NL8105744A (fr)
NZ (1)	NZ198215A (fr)
PH (1)	PH17742A (fr)
SE (1)	SE442110B (fr)
SG (1)	SG56084G (fr)
ZA (1)	ZA821139B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6179685U (fr) *	1984-10-26	1986-05-27
JPS61207304A (ja) *	1985-03-11	1986-09-13	Toyo Soda Mfg Co Ltd	農園芸用殺菌剤
JPH0445817Y2 (fr) *	1988-09-09	1992-10-28
US5610198A (en) *	1994-03-18	1997-03-11	The United States Of America As Represented By The Department Of Health And Human Services	Anti-mycobacterial compositions and their use for the treatment of tuberculosis and related diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3558640A (en) *	1967-12-20	1971-01-26	Merck & Co Inc	Certain pyridyl and thiazolyl methylthiopropionic acids and derivatives
GB1434271A (en) *	1972-09-28	1976-05-05	Squibb & Sons Inc	Cephalosporins
US4246263A (en) *	1979-10-15	1981-01-20	Pfizer Inc.	Antiinflammatory and immunoregulatory pyrimidines, their method of use and pharmaceutical compositions

1981
- 1981-06-26 US US06/276,242 patent/US4371696A/en not_active Expired - Fee Related
- 1981-08-31 NZ NZ198215A patent/NZ198215A/en unknown
- 1981-08-31 GR GR65912A patent/GR75753B/el unknown
- 1981-08-31 IL IL63699A patent/IL63699A0/xx not_active IP Right Cessation
- 1981-09-16 BE BE0/205976A patent/BE890374R/fr not_active IP Right Cessation
- 1981-11-06 GB GB08133616A patent/GB2100600B/en not_active Expired
- 1981-11-17 AU AU77553/81A patent/AU528433B2/en not_active Ceased
- 1981-11-24 IE IE2748/81A patent/IE51727B1/en unknown
- 1981-11-26 FR FR8122143A patent/FR2508904B2/fr not_active Expired
- 1981-11-27 SE SE8107101A patent/SE442110B/sv not_active IP Right Cessation
- 1981-12-01 CH CH7697/81A patent/CH648483A5/fr not_active IP Right Cessation
- 1981-12-10 LU LU83827A patent/LU83827A1/fr unknown
- 1981-12-21 NL NL8105744A patent/NL8105744A/nl not_active Application Discontinuation
1982
- 1982-01-11 PH PH26722A patent/PH17742A/en unknown
- 1982-01-18 IT IT19162/82A patent/IT1200569B/it active
- 1982-02-05 JP JP57017374A patent/JPS58916A/ja active Pending
- 1982-02-22 ZA ZA821139A patent/ZA821139B/xx unknown
- 1982-04-27 DE DE19823215648 patent/DE3215648A1/de not_active Ceased
1984
- 1984-08-13 SG SG560/84A patent/SG56084G/en unknown
- 1984-09-24 KE KE3458A patent/KE3458A/xx unknown
1985
- 1985-12-30 MY MY351/85A patent/MY8500351A/xx unknown
1987
- 1987-09-17 HK HK670/87A patent/HK67087A/xx unknown

Also Published As

Publication number	Publication date
LU83827A1 (fr)	1982-05-07
PH17742A (en)	1984-11-27
IE812748L (en)	1982-12-26
IT8219162A0 (it)	1982-01-18
US4371696A (en)	1983-02-01
HK67087A (en)	1987-09-25
FR2508904B2 (fr)	1985-11-29
IT1200569B (it)	1989-01-27
IL63699A0 (en)	1981-11-30
SE442110B (sv)	1985-12-02
GR75753B (fr)	1984-08-02
AU528433B2 (en)	1983-04-28
ZA821139B (en)	1983-01-26
KE3458A (en)	1984-10-12
JPS58916A (ja)	1983-01-06
GB2100600B (en)	1983-09-14
NL8105744A (nl)	1983-01-17
DE3215648A1 (de)	1983-01-13
NZ198215A (en)	1984-07-06
IE51727B1 (en)	1987-03-04
GB2100600A (en)	1983-01-06
FR2508904A2 (fr)	1983-01-07
CH648483A5 (fr)	1985-03-29
BE890374R (fr)	1982-03-16
SG56084G (en)	1985-03-08
SE8107101L (sv)	1982-12-27

Publication	Publication Date	Title
DE3377574D1 (en)	1988-09-08	Hydroxybenzylamino derivatives as anti-inflammatory agents
NZ212956A (en)	1988-09-29	Pyridine derivatives and pharmaceutical compositions
EP0080442A3 (en)	1983-09-07	Di-galactose derivatives and their preparation
DE3467894D1 (en)	1988-01-14	Dihydroxybenzamide derivatives having anti-inflammatory activity
ZA853379B (en)	1985-12-24	Substituted 1-oxa-dethiachphalosporins as anti-inflammatory and antidegenerative agents
IL64774A (en)	1985-06-30	Hexahydro-trans and tetrahydropyridoindole derivatives
ZA854947B (en)	1986-02-26	Beta-lactam derivatives as anti-inflammatory and anti-degenerative agents
GB2100600B (en)	1983-09-14	Pyridine derivatives as anti-inflammatory and immunoregulatory agents
AR242212A1 (es)	1993-03-31	Un proceso para la preparacion de nuevos derivados de 1,3-dihidro-6-¡1- ciano-1-isopropil-n-fenetil-n-metil-omega-aminoalquil-7-hidro xi-furo-(3,4c)-piridina
JPS57169450A (en)	1982-10-19	Fluorophenacyl-amine derivative and application to remedy
GB8422461D0 (en)	1984-10-10	Pyridine derivatives
GB8426738D0 (en)	1984-11-28	Pyridine derivatives
GB8501158D0 (en)	1985-02-20	Pregnene derivatives
DE3266355D1 (en)	1985-10-24	Octahydrotetracyanoquinodimethane and derivatives thereof
AU7755381A (en)	1982-12-30	Anti-inflammatory immunoregulatory pyridine derivatives
DE3572976D1 (en)	1989-10-19	Acrylamidobenzoic acid derivatives and their use
DE3261765D1 (en)	1985-02-14	Aminonaphthacene derivatives and their production
ZA822008B (en)	1983-02-23	New pyridine derivatives
GB8520007D0 (en)	1985-09-18	Pyridine derivatives
GB8520169D0 (en)	1985-09-18	Pyridine derivatives
GB8521304D0 (en)	1985-10-02	Pyridine derivatives
GB8507008D0 (en)	1985-04-24	Pyridine derivatives
JPS57179198A (en)	1982-11-04	3-oxo-17 alpha-ethynyl-17 beta-trifluoroacetoxy- gonane derivatives and manufacture
GB2167064B (en)	1988-01-06	Pyridine derivatives
ZA821968B (en)	1983-01-26	Pyridine derivatives