NL1007088C2 - Samenstelling voor het bestrijden van parasieten. - Google Patents

Samenstelling voor het bestrijden van parasieten. Download PDF

Info

Publication number: NL1007088C2
Authority: NL; Netherlands
Prior art keywords: alkyl; group; haloalkyl; compound; composition according
Prior art date: 1996-09-19

Application number

NL1007088A

Other languages

English (en)

Dutch (nl)

Inventor

Philippe Jeannin

Jean-Pierre Etchegaray

Bruno Julia

Anne-Marie Huet

Andre Weil

Original Assignee

Merial Sas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-19

Filing date

1997-09-19

Publication date

1998-03-20

1997-09-19 Application filed by Merial Sas filed Critical Merial Sas

1998-03-20 Application granted granted Critical

1998-03-20 Publication of NL1007088C2 publication Critical patent/NL1007088C2/nl

Links

239000000203 mixture Substances 0.000 title claims description 77
244000045947 parasite Species 0.000 title claims description 21
150000001875 compounds Chemical class 0.000 claims description 67
241001465754 Metazoa Species 0.000 claims description 38
125000001188 haloalkyl group Chemical group 0.000 claims description 35
125000000217 alkyl group Chemical group 0.000 claims description 30
125000005843 halogen group Chemical group 0.000 claims description 24
AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 claims description 20
229960002418 ivermectin Drugs 0.000 claims description 20
SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 claims description 17
238000009472 formulation Methods 0.000 claims description 17
238000000034 method Methods 0.000 claims description 17
239000005660 Abamectin Substances 0.000 claims description 15
239000003112 inhibitor Substances 0.000 claims description 15
239000004530 micro-emulsion Substances 0.000 claims description 15
125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 14
-1 moxydectine Natural products 0.000 claims description 14
238000002425 crystallisation Methods 0.000 claims description 13
230000008025 crystallization Effects 0.000 claims description 13
244000079386 endoparasite Species 0.000 claims description 10
FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 claims description 9
244000078703 ectoparasite Species 0.000 claims description 8
229910052739 hydrogen Inorganic materials 0.000 claims description 8
239000001257 hydrogen Substances 0.000 claims description 8
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 8
241000282326 Felis catus Species 0.000 claims description 7
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IBSREHMXUMOFBB-JFUDTMANSA-N 5u8924t11h Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C(C)C)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 IBSREHMXUMOFBB-JFUDTMANSA-N 0.000 claims description 5
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125000004093 cyano group Chemical group *C#N 0.000 claims description 4
QLFZZSKTJWDQOS-YDBLARSUSA-N doramectin Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C3CCCCC3)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C QLFZZSKTJWDQOS-YDBLARSUSA-N 0.000 claims description 4
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125000001072 heteroaryl group Chemical group 0.000 claims description 4
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229910052760 oxygen Inorganic materials 0.000 claims description 4
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239000011593 sulfur Chemical group 0.000 claims description 4
230000009885 systemic effect Effects 0.000 claims description 4
239000003096 antiparasitic agent Substances 0.000 claims description 3
238000002156 mixing Methods 0.000 claims description 3
230000000590 parasiticidal effect Effects 0.000 claims description 3
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XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 description 7
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125000004429 atom Chemical group 0.000 description 1
JPNZKPRONVOMLL-UHFFFAOYSA-N azane;octadecanoic acid Chemical compound [NH4+].CCCCCCCCCCCCCCCCCC([O-])=O JPNZKPRONVOMLL-UHFFFAOYSA-N 0.000 description 1
239000011805 ball Substances 0.000 description 1
235000019445 benzyl alcohol Nutrition 0.000 description 1
229960003237 betaine Drugs 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
230000036765 blood level Effects 0.000 description 1
238000009835 boiling Methods 0.000 description 1
CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 description 1
235000013539 calcium stearate Nutrition 0.000 description 1
239000008116 calcium stearate Substances 0.000 description 1
239000000969 carrier Substances 0.000 description 1
239000004359 castor oil Substances 0.000 description 1
235000019438 castor oil Nutrition 0.000 description 1
238000004140 cleaning Methods 0.000 description 1
239000000470 constituent Substances 0.000 description 1
239000002537 cosmetic Substances 0.000 description 1
239000006071 cream Substances 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
239000006185 dispersion Substances 0.000 description 1
125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
239000003814 drug Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
230000001793 endectocide Effects 0.000 description 1
230000008029 eradication Effects 0.000 description 1
LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
150000002191 fatty alcohols Chemical class 0.000 description 1
210000003608 fece Anatomy 0.000 description 1
210000001035 gastrointestinal tract Anatomy 0.000 description 1
125000005456 glyceride group Chemical group 0.000 description 1
ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
229940100242 glycol stearate Drugs 0.000 description 1
150000002334 glycols Chemical class 0.000 description 1
229930182470 glycoside Natural products 0.000 description 1
150000002338 glycosides Chemical class 0.000 description 1
230000035876 healing Effects 0.000 description 1
WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
VQLXKLZFUXSBOJ-UHFFFAOYSA-N hypochlorous acid;octadecan-1-amine Chemical class ClO.CCCCCCCCCCCCCCCCCCN VQLXKLZFUXSBOJ-UHFFFAOYSA-N 0.000 description 1
239000007943 implant Substances 0.000 description 1
239000007972 injectable composition Substances 0.000 description 1
229910052500 inorganic mineral Inorganic materials 0.000 description 1
230000003993 interaction Effects 0.000 description 1
SYJRVVFAAIUVDH-UHFFFAOYSA-N ipa isopropanol Chemical compound CC(C)O.CC(C)O SYJRVVFAAIUVDH-UHFFFAOYSA-N 0.000 description 1
QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
230000002147 killing effect Effects 0.000 description 1
239000000787 lecithin Substances 0.000 description 1
235000010445 lecithin Nutrition 0.000 description 1
229940067606 lecithin Drugs 0.000 description 1
239000012669 liquid formulation Substances 0.000 description 1
230000005923 long-lasting effect Effects 0.000 description 1
238000011866 long-term treatment Methods 0.000 description 1
230000007774 longterm Effects 0.000 description 1
239000000594 mannitol Substances 0.000 description 1
235000010355 mannitol Nutrition 0.000 description 1
239000000463 material Substances 0.000 description 1
229940057917 medium chain triglycerides Drugs 0.000 description 1
150000002734 metacrylic acid derivatives Chemical class 0.000 description 1
239000002480 mineral oil Substances 0.000 description 1
201000002266 mite infestation Diseases 0.000 description 1
ZHALDANPYXAMJF-UHFFFAOYSA-N octadecanoate;tris(2-hydroxyethyl)azanium Chemical compound OCC[NH+](CCO)CCO.CCCCCCCCCCCCCCCCCC([O-])=O ZHALDANPYXAMJF-UHFFFAOYSA-N 0.000 description 1
239000002674 ointment Substances 0.000 description 1
ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
230000003071 parasitic effect Effects 0.000 description 1
230000001717 pathogenic effect Effects 0.000 description 1
231100000255 pathogenic effect Toxicity 0.000 description 1
229920000223 polyglycerol Polymers 0.000 description 1
239000011591 potassium Substances 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
229940114930 potassium stearate Drugs 0.000 description 1
239000004540 pour-on Substances 0.000 description 1
230000002035 prolonged effect Effects 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
229910002059 quaternary alloy Inorganic materials 0.000 description 1
150000003242 quaternary ammonium salts Chemical class 0.000 description 1
230000033764 rhythmic process Effects 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
229940083542 sodium Drugs 0.000 description 1
239000001632 sodium acetate Substances 0.000 description 1
235000017281 sodium acetate Nutrition 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
229940001584 sodium metabisulfite Drugs 0.000 description 1
235000010262 sodium metabisulphite Nutrition 0.000 description 1
AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
235000019345 sodium thiosulphate Nutrition 0.000 description 1
VCLVUNFJTOOMIR-UHFFFAOYSA-M sodium;acetyl sulfate Chemical compound [Na+].CC(=O)OS([O-])(=O)=O VCLVUNFJTOOMIR-UHFFFAOYSA-M 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
241000894007 species Species 0.000 description 1
238000001228 spectrum Methods 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
230000002459 sustained effect Effects 0.000 description 1
239000011885 synergistic combination Substances 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
229940029614 triethanolamine stearate Drugs 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Pest Control & Pesticides (AREA)
Agronomy & Crop Science (AREA)
Wood Science & Technology (AREA)
Plant Pathology (AREA)
Dentistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)

NL1007088A 1996-09-19 1997-09-19 Samenstelling voor het bestrijden van parasieten. NL1007088C2 (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9611446		1996-09-19
FR9611446A FR2753377B1 (fr)	1996-09-19	1996-09-19	Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides

Publications (1)

Publication Number	Publication Date
NL1007088C2 true NL1007088C2 (nl)	1998-03-20

Family

ID=9495897

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL1007088A NL1007088C2 (nl)	1996-09-19	1997-09-19	Samenstelling voor het bestrijden van parasieten.

Country Status (18)

Country	Link
US (1)	US6482425B1 (de)
JP (2)	JP3756194B2 (de)
AU (1)	AU733408B2 (de)
BE (1)	BE1011370A5 (de)
BR (1)	BR9713469B1 (de)
CH (1)	CH693732A8 (de)
DE (2)	DE19781981T1 (de)
ES (1)	ES2166300B1 (de)
FR (1)	FR2753377B1 (de)
GB (1)	GB2334888B (de)
HR (1)	HRP970510A2 (de)
IE (1)	IE970675A1 (de)
IT (1)	IT1297193B1 (de)
MA (1)	MA24360A1 (de)
NL (1)	NL1007088C2 (de)
SE (1)	SE9900893L (de)
WO (1)	WO1998011780A1 (de)
ZA (1)	ZA978355B (de)

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1996
- 1996-09-19 FR FR9611446A patent/FR2753377B1/fr not_active Expired - Lifetime
1997
- 1997-09-11 IE IE970675A patent/IE970675A1/en not_active IP Right Cessation
- 1997-09-15 JP JP51433498A patent/JP3756194B2/ja not_active Expired - Lifetime
- 1997-09-15 DE DE19781981T patent/DE19781981T1/de active Pending
- 1997-09-15 ES ES009950013A patent/ES2166300B1/es not_active Expired - Fee Related
- 1997-09-15 DE DE19781981A patent/DE19781981B3/de not_active Expired - Lifetime
- 1997-09-15 BR BRPI9713469-4B1A patent/BR9713469B1/pt not_active IP Right Cessation
- 1997-09-15 GB GB9906314A patent/GB2334888B/en not_active Expired - Lifetime
- 1997-09-15 WO PCT/FR1997/001548 patent/WO1998011780A1/fr not_active Ceased
- 1997-09-15 CH CH00501/99A patent/CH693732A8/fr not_active IP Right Cessation
- 1997-09-15 AU AU42110/97A patent/AU733408B2/en not_active Expired
- 1997-09-17 ZA ZA978355A patent/ZA978355B/xx unknown
- 1997-09-17 MA MA24800A patent/MA24360A1/fr unknown
- 1997-09-18 BE BE9700759A patent/BE1011370A5/fr not_active IP Right Cessation
- 1997-09-18 IT IT97TO000823A patent/IT1297193B1/it active IP Right Grant
- 1997-09-19 NL NL1007088A patent/NL1007088C2/nl not_active IP Right Cessation
- 1997-09-19 HR HR9611446A patent/HRP970510A2/hr not_active Application Discontinuation
1999
- 1999-03-12 SE SE9900893A patent/SE9900893L/xx not_active Application Discontinuation
- 1999-03-17 US US09/271,470 patent/US6482425B1/en not_active Expired - Lifetime
2005
- 2005-09-21 JP JP2005273962A patent/JP2006056897A/ja active Pending

Also Published As

Publication number	Publication date
HRP970510A2 (en)	1998-08-31
ES2166300A1 (es)	2002-04-01
CH693732A8 (fr)	2004-02-27
ZA978355B (en)	1999-03-17
ITTO970823A1 (it)	1999-03-18
GB9906314D0 (en)	1999-05-12
SE9900893D0 (sv)	1999-03-12
BR9713469A (pt)	2000-04-11
DE19781981T1 (de)	1999-09-23
AU733408C (en)	1998-04-14
FR2753377A1 (fr)	1998-03-20
FR2753377B1 (fr)	1999-09-24
BR9713469B1 (pt)	2013-10-29
GB2334888B (en)	2001-02-28
AU733408B2 (en)	2001-05-10
JP2006056897A (ja)	2006-03-02
BE1011370A5 (fr)	1999-08-03
CH693732A5 (fr)	2004-01-15
IE970675A1 (en)	1999-01-13
JP2001503390A (ja)	2001-03-13
IT1297193B1 (it)	1999-08-03
GB2334888A (en)	1999-09-08
JP3756194B2 (ja)	2006-03-15
AU4211097A (en)	1998-04-14
DE19781981B3 (de)	2013-05-29
US6482425B1 (en)	2002-11-19
MA24360A1 (fr)	1998-07-01
WO1998011780A1 (fr)	1998-03-26
SE9900893L (sv)	1999-04-16
ES2166300B1 (es)	2003-09-16

Legal Events

Date	Code	Title	Description
1998-05-06	PD2A	A request for search or an international type search has been filed
2017-09-20	MK	Patent expired because of reaching the maximum lifetime of a patent	Effective date: 20170918

Publication	Publication Date	Title
AU733408B2 (en)	2001-05-10	New parasiticide combination
US6426333B1 (en)	2002-07-30	Spot-on formulations for combating parasites
US20030166688A1 (en)	2003-09-04	Spot-on formulations for combating parasites
EP1887866B1 (de)	2017-12-06	Spot-on formulierungen zur parasitenbekämpfung
JP3702965B2 (ja)	2005-10-05	哺乳動物、特に犬猫のノミを防除するための殺虫剤の組合せ
NL1004155C2 (nl)	1997-06-17	Antiparasitaire samenstelling voor de behandeling en de bescherming van gezelschapsdieren.
ES2823760T3 (es)	2021-05-10	Formulaciones para administración tópica local que contienen indoxacarb
NL1006532C2 (nl)	1998-03-27	Werkwijze voor het bestrijden van parasieten en vooral van ectoparasieten van gewervelde dieren, vooral van zoogdieren en samenstellingen voor de toepassing van de werkwijze.
JP5425109B2 (ja)	2014-02-26	局所用外部寄生虫駆除剤組成物
NL1005673C2 (nl)	1997-11-18	Oplossing voor directe aanbrenging op de huid voor gebruik als anti-parasitair middel bij runderen en schapen.
AU2005223991B2 (en)	2011-02-10	Parasiticidal agents
AU773119B2 (en)	2004-05-20	Methods for eliminating parasites and in particular ectoparasites of vertebrates, particularly of mammals and compositions for implementing these methods
HK1116007B (en)	2018-07-13	Spot-on formulations for combating parasites
HK1116007A (en)	2008-12-19	Spot-on formulations for combating parasites
IE83881B1 (en)	2005-04-20	Methods for removing parasites and in particular ectoparasites of vertebrates, in particular of mammals, and compositions for the implementation of this method.