NL300388I2 - Een werkwijze voor het maken van opthalmische suspensies die brinozolamide bevatten - Google Patents

Een werkwijze voor het maken van opthalmische suspensies die brinozolamide bevatten

Info

Publication number: NL300388I2
Authority: NL; Netherlands
Prior art keywords: brinozolamide; suspensions containing; ophthalmic suspensions; making ophthalmic; making
Prior art date: 1996-12-11

Application number

NL300388C

Other languages

English (en)

Dutch (nl)

Other versions

NL300388I1 (nl

Original Assignee

Alcon Lab Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-11

Filing date

2009-05-11

Publication date

2010-02-01

2009-05-11 Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc

2009-07-01 Publication of NL300388I1 publication Critical patent/NL300388I1/nl

2010-02-01 Publication of NL300388I2 publication Critical patent/NL300388I2/nl

Links

239000000725 suspension Substances 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
HCRKCZRJWPKOAR-JTQLQIEISA-N brinzolamide Chemical compound CCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S(N)(=O)=O)S2 HCRKCZRJWPKOAR-JTQLQIEISA-N 0.000 abstract 2
229960000722 brinzolamide Drugs 0.000 abstract 2
239000002876 beta blocker Substances 0.000 abstract 1
229940097320 beta blocking agent Drugs 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NL300388C 1996-12-11 2009-05-11 Een werkwijze voor het maken van opthalmische suspensies die brinozolamide bevatten NL300388I2 (nl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US3282096P	1996-12-11	1996-12-11
US08/886,933 US6071904A (en)	1996-12-11	1997-07-02	Process for manufacturing ophthalmic suspensions
PCT/US1997/015727 WO1998025620A1 (en)	1996-12-11	1997-09-05	Process for manufacturing ophthalmic suspensions

Publications (2)

Publication Number	Publication Date
NL300388I1 NL300388I1 (nl)	2009-07-01
NL300388I2 true NL300388I2 (nl)	2010-02-01

Family

ID=26708929

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL300388C NL300388I2 (nl)	1996-12-11	2009-05-11	Een werkwijze voor het maken van opthalmische suspensies die brinozolamide bevatten

Country Status (13)

Country	Link
US (1)	US6071904A (2)
EP (1)	EP0941094B1 (2)
JP (1)	JP3611863B2 (2)
AT (1)	ATE209917T1 (2)
CA (1)	CA2274680C (2)
DE (2)	DE69708912T2 (2)
DK (1)	DK0941094T3 (2)
ES (1)	ES2169416T3 (2)
FR (1)	FR09C0022I2 (2)
LU (1)	LU91554I2 (2)
NL (1)	NL300388I2 (2)
PT (1)	PT941094E (2)
WO (1)	WO1998025620A1 (2)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000001365A1 (en) *	1998-06-30	2000-01-13	Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab)	Prolonged release ophthalmic compositions containing a fluoroquinolone
EP1392322A1 (en) *	2001-05-21	2004-03-03	Alcon, Inc.	Method of treating dry eye disorders
US6872382B1 (en)	2001-05-21	2005-03-29	Alcon, Inc.	Use of selective PDE IV inhibitors to treat dry eye disorders
US7112588B2 (en) *	2001-05-21	2006-09-26	Alcon, Inc.	Use of proteasome inhibitors to treat dry eye disorders
BR0209883A (pt)	2001-05-21	2004-06-08	Alcon Inc	Uso de inibidores da proteasoma para o tratamento de distúrbios do olho seco
JP2004527578A (ja)	2001-05-21	2004-09-09	アルコン，インコーポレイテッド	ドライアイ障害を処置するためのＮＦ−κＢインヒビターの使用
TWI298257B (en)	2001-05-31	2008-07-01	Allergan Inc	Hypotensive lipid and timolol compositions and methods of using same
US6645994B1 (en)	2001-06-01	2003-11-11	Alcon, Inc.	Method of treating dry eye disorders
EP1480636B1 (en) *	2002-03-01	2007-04-18	Novagali Pharma SA	Self emulsifying drug delivery systems for taxoids
PT1586316E (pt)	2003-01-21	2008-05-28	Senju Pharma Co	Preparação líquida aquosa contendo ácido 2-amino-3-(4- bromobenzoil)fenilacético
DE602005026225D1 (de) *	2004-03-12	2011-03-24	Cipla Ltd	Sterilisationsprozess für Steroide
ES2428868T3 (es) *	2006-07-28	2013-11-12	Novagali Pharma S.A.	Composiciones que contienen compuestos de amonio cuaternario
WO2008035246A2 (en)	2006-07-28	2008-03-27	Novagali Pharma Sa	Compositions containing quaternary ammonium compounds
TWI544927B (zh)	2008-03-17	2016-08-11	愛爾康研究有限公司	具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
TWI489997B (zh)	2009-06-19	2015-07-01	Alcon Res Ltd	含有硼酸－多元醇錯合物之水性藥學組成物
EP2506878A2 (en) *	2009-12-03	2012-10-10	Lupin Limited	Process for preparing pharmaceutical ophthalmic compositions
EP2394637A1 (en) *	2010-05-21	2011-12-14	Zaklady Farmaceutyczne Polpharma SA	Process for obtaining sterile brinzolamide suspensions
US9061034B2 (en)	2010-07-29	2015-06-23	Allergan, Inc.	Preservative free bimatoprost and timolol solutions
KR101820184B1 (ko)	2010-07-29	2018-01-18	알러간, 인코포레이티드	방부제가 없는 비마토프로스트 및 티몰롤 용액
WO2012053011A2 (en)	2010-10-18	2012-04-26	Usv Limited	Ophthalmic compositions comprising brinzolamide
WO2013025696A1 (en)	2011-08-15	2013-02-21	Teva Pharmaceutical Industries Ltd.	Ophthalmic formulations and processes for their preparation
EP2638909A1 (en)	2012-03-15	2013-09-18	Azad Pharmaceutical Ingredients AG	Process for preparing sterile Brinzolamide
GR1007906B (el) *	2012-03-22	2013-05-30	Φαρματεν Αβεε,	Οφθαλμικο φαρμακευτικο σκευασμα περιεχον ενα αναστολεα καρβονικης ανυδρασης και μεθοδος για την παρασκευη αυτου
US10953115B2 (en)	2012-05-09	2021-03-23	Icrom S.R.L.	Production of sterile active pharmaceutical ingredients
WO2013175285A1 (en)	2012-05-21	2013-11-28	Aurobindo Pharma Limited	Process for preparing ophthalmic suspension of brinzolamde
US9649319B2 (en)	2012-10-11	2017-05-16	Indoco Remedies Limited	Process for manufacturing sterile brinzolamide ophthalmic suspension
CN104721136A (zh) *	2013-02-21	2015-06-24	四川大学	一种布佐林胺眼用纳米混悬剂及其制备方法
CA2924562A1 (en) *	2013-10-17	2015-04-23	Sentiss Pharma Private Limited	Preservative-free ophthalmic pharmaceutical formulation
US9820991B2 (en) *	2013-11-08	2017-11-21	Sentiss Pharma Private Limited	Pharmaceutical composition comprising brinzolamide
US10463674B2 (en)	2013-11-08	2019-11-05	Sentiss Pharma Private Limited	Process for manufacturing sterile ophthalmic pharmaceutical suspensions
ES2838756T3 (es)	2014-01-24	2021-07-02	Sentiss Pharma Private Ltd	Composición farmacéutica que comprende brinzolamida
PL407710A1 (pl)	2014-03-28	2015-10-12	Instytut Farmaceutyczny	Sposób wytwarzania preparatu kropli do oczu w postaci zawiesiny zawierającej brynzolamid i preparat wytworzony tym sposobem
JP6279395B2 (ja) *	2014-05-01	2018-02-14	東亜薬品株式会社	ブリンゾラミド懸濁性点眼液組成物の製造方法
EP3209331B1 (en)	2014-10-20	2023-07-12	Sentiss Pharma Private Limited	Ophthalmic solution
TWI700085B (zh) *	2015-06-22	2020-08-01	新源生物科技股份有限公司	酪胺酸激酶抑制劑之眼用調配物的用途
CN107582519A (zh) *	2017-06-01	2018-01-16	合肥远志医药科技开发有限公司	一种布林佐胺滴眼液制剂及其制备方法
GR1009419B (el)	2017-11-07	2018-12-14	Φαρματεν Αβεε	Οφθαλμικο φαρμακευτικο σκευασμα που περιεχει εναν συνδυασμο βρινζολαμιδης και βριμονιδινης και μεθοδος για την παρασκευη αυτου
WO2019207380A1 (en)	2018-04-25	2019-10-31	Shilpa Medicare Limited	Ophthalmic compositions of brinzolamide
GR1009616B (el) *	2018-07-20	2019-10-11	Φαρματεν Α.Β.Ε.Ε.	Οφθαλμικο φαρμακευτικο σκευασμα που περιεχει βρινζολαμιδη και τιμολολη και μεθοδος παρασκευης αυτου
WO2020240451A1 (en)	2019-05-29	2020-12-03	Lupin Limited	In-situ gelling nanoemulsion of brinzolamide
US11850249B2 (en)	2020-10-05	2023-12-26	Somerset Therapeutics, Llc	Methods of efficiently reducing intraocular pressure
WO2024236599A1 (en)	2023-05-16	2024-11-21	Micro Labs Limited	Ophthalmic solution of brinzolamide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5378703A (en) *	1990-04-09	1995-01-03	Alcon Laboratories, Inc.	Sulfonamides useful as carbonic anhydrase inhibitors
RO113612B1 (ro) *	1991-04-17	1998-09-30	Merck & Co Inc	Compozitie oftalmica
WO1993016701A2 (en) *	1992-02-21	1993-09-02	Alcon Laboratories, Inc.	Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers
US5362758A (en) *	1992-09-18	1994-11-08	Pfizer Inc.	Ophthalmic piroxicam solution
US5346702A (en) *	1992-12-04	1994-09-13	Sterling Winthrop Inc.	Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization
US5429824A (en) *	1992-12-15	1995-07-04	Eastman Kodak Company	Use of tyloxapole as a nanoparticle stabilizer and dispersant
US5576016A (en) *	1993-05-18	1996-11-19	Pharmos Corporation	Solid fat nanoemulsions as drug delivery vehicles
US5422116A (en) *	1994-02-18	1995-06-06	Ciba-Geigy Corporation	Liquid ophthalmic sustained release delivery system

1997
- 1997-07-02 US US08/886,933 patent/US6071904A/en not_active Expired - Lifetime
- 1997-09-05 CA CA002274680A patent/CA2274680C/en not_active Expired - Lifetime
- 1997-09-05 WO PCT/US1997/015727 patent/WO1998025620A1/en not_active Ceased
- 1997-09-05 DE DE69708912T patent/DE69708912T2/de not_active Expired - Lifetime
- 1997-09-05 DK DK97939835T patent/DK0941094T3/da active
- 1997-09-05 AT AT97939835T patent/ATE209917T1/de active
- 1997-09-05 JP JP52598698A patent/JP3611863B2/ja not_active Expired - Lifetime
- 1997-09-05 ES ES97939835T patent/ES2169416T3/es not_active Expired - Lifetime
- 1997-09-05 DE DE122009000016C patent/DE122009000016I1/de active Pending
- 1997-09-05 PT PT97939835T patent/PT941094E/pt unknown
- 1997-09-05 EP EP97939835A patent/EP0941094B1/en not_active Expired - Lifetime
2009
- 2009-04-22 LU LU91554C patent/LU91554I2/fr unknown
- 2009-05-11 NL NL300388C patent/NL300388I2/nl unknown
- 2009-05-25 FR FR09C0022C patent/FR09C0022I2/fr active Active

Also Published As

Publication number	Publication date
JP2000501749A (ja)	2000-02-15
JP3611863B2 (ja)	2005-01-19
AU4183897A (en)	1998-07-03
FR09C0022I2 (2)	2010-06-11
EP0941094A1 (en)	1999-09-15
HK1019704A1 (en)	2000-02-25
DE122009000016I1 (de)	2009-06-25
WO1998025620A1 (en)	1998-06-18
CA2274680A1 (en)	1998-06-18
ES2169416T3 (es)	2002-07-01
ATE209917T1 (de)	2001-12-15
FR09C0022I1 (2)	2009-09-25
NL300388I1 (nl)	2009-07-01
DE69708912D1 (de)	2002-01-17
LU91554I2 (fr)	2009-06-22
EP0941094B1 (en)	2001-12-05
DK0941094T3 (da)	2002-01-07
AU718079B2 (en)	2000-04-06
CA2274680C (en)	2003-11-18
DE69708912T2 (de)	2002-04-11
US6071904A (en)	2000-06-06
PT941094E (pt)	2002-05-31

Publication	Publication Date	Title
NL300388I1 (nl)	2009-07-01	Een werkwijze voor het maken van opthalmische suspensies die brinozolamide bevatten.
DE59607225D1 (de)	2001-08-09	Scherenförmiges, chirurgisches werkzeug und verfahren zu dessen herstellung
DE69431356D1 (de)	2002-10-17	Computermonitor mit integriertem stereolautsprecher-richtmikrofon, und verfahren zur herstellung
DE69112407D1 (de)	1995-09-28	Hörgerät und verfahren zu seiner herstellung.
PL351687A1 (en)	2003-06-02	Polyolefins and method for the production thereof
ATE379971T1 (de)	2007-12-15	Disinfektionsmittel und verfahren zu dessen herstellung
AU7580100A (en)	2001-04-17	Glare-free intraocular lens and method for using the same
DE69633610D1 (de)	2004-11-18	Flüssigkeitabsorbierendes material und verfahren zu dessen herstellung
ATE199915T1 (de)	2001-04-15	Syndiotaktische/isotaktische blockpolyolefinen, katalysatore und verfahren zu ihrer herstellung
AU2351001A (en)	2001-06-04	Stent and method for the production thereof
NL1003956A1 (nl)	1997-03-06	Werkwijze voor het vervaardigen van een drager voor registratie materiaal.
DE69508453D1 (de)	1999-04-29	Vorbehandelte Papierdeckel, Verfahren und Vorrichtung zu dessen Herstellung
DE69813008D1 (de)	2003-05-08	Luftreifen und verfahren zu dessen herstellung
NL1000668C1 (nl)	1996-08-16	Werkwijze voor het vervormen van een plaat en een hiertoe geschikte plaat.
ATA8299A (de)	2002-02-15	Plattenförmiges presswerkzeug und verfahren zu dessen herstellung
DE69807261D1 (de)	2002-09-19	Hydraulisch gebundene, geschäumte formkörper und verfahren zu dessen herstellung
NL192291B (nl)	1997-01-06	Werkwijze voor het maken van een fermentproduct, daarmee verkregen korrelvormig fermentproduct en toepassing van het fermentproduct.
AU2003248919A1 (en)	2004-02-23	Catalysts and process for making polyolefins
DE69803765D1 (de)	2002-03-21	Mehrschichtgleitteil und verfahren zu dessen herstellung
DE69829743D1 (de)	2005-05-19	Laser-geschweisstes lager und verfahren zu dessen herstellung
NL194568B (nl)	2002-03-01	Werkwijze voor het vervaardigen van een halfgeleiderlaser.
DE69625174D1 (de)	2003-01-16	Gleitteil und verfahren zu dessen herstellung
NL1006184A1 (nl)	1997-12-03	Werkwijze voor het prepareren van een hydrofobe plaat.
NL1004705A1 (nl)	1997-06-17	Werkwijze voor de productie van kleine alkenen.
AU8057998A (en)	1998-12-30	Knowledge representation system including integrated knowledge-base and database, and method and apparatus for utilizing the same