NL7700396A - Verbeteringen in en met betrekking tot de berei- ding van halfsynthetische penicilline antibioti- ca. - Google Patents

Verbeteringen in en met betrekking tot de berei- ding van halfsynthetische penicilline antibioti- ca.

Info

Publication number
NL7700396A
NL7700396A NL7700396A NL7700396A NL7700396A NL 7700396 A NL7700396 A NL 7700396A NL 7700396 A NL7700396 A NL 7700396A NL 7700396 A NL7700396 A NL 7700396A NL 7700396 A NL7700396 A NL 7700396A
Authority
NL
Netherlands
Prior art keywords
relating
semi
preparation
penicillin antibiotic
synthetic penicillin
Prior art date
Application number
NL7700396A
Other languages
English (en)
Dutch (nl)
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of NL7700396A publication Critical patent/NL7700396A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/10—Modification of an amino radical directly attached in position 6
    • C07D499/12—Acylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
NL7700396A 1976-01-15 1977-01-14 Verbeteringen in en met betrekking tot de berei- ding van halfsynthetische penicilline antibioti- ca. NL7700396A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47643/76A IT1053313B (it) 1976-01-15 1976-01-15 Procedimento per produrre antibiotici semisintetici

Publications (1)

Publication Number Publication Date
NL7700396A true NL7700396A (nl) 1977-07-19

Family

ID=11261624

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7700396A NL7700396A (nl) 1976-01-15 1977-01-14 Verbeteringen in en met betrekking tot de berei- ding van halfsynthetische penicilline antibioti- ca.

Country Status (14)

Country Link
JP (1) JPS5287191A (fr)
AU (1) AU512150B2 (fr)
BE (1) BE850382A (fr)
CH (1) CH627182A5 (fr)
DE (1) DE2701406A1 (fr)
DK (1) DK13977A (fr)
ES (1) ES455026A1 (fr)
FR (1) FR2338279A1 (fr)
GB (1) GB1569427A (fr)
IT (1) IT1053313B (fr)
NL (1) NL7700396A (fr)
SE (1) SE437989B (fr)
YU (1) YU9277A (fr)
ZA (1) ZA77195B (fr)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB958478A (en) * 1962-03-13 1964-05-21 Beecham Res Lab Production of penicillins
BE638819A (fr) * 1962-10-17
US3351597A (en) * 1966-11-23 1967-11-07 Lilly Co Eli Process for acylating 7-amino cephalosporanic acid
ZA695612B (en) * 1968-08-23 1971-03-31 Lilly Co Eli Preparation of cephalosporin compounds
US3595855A (en) * 1968-12-05 1971-07-27 American Home Prod Process for producing aminopenicillins
IT1043957B (it) * 1970-12-31 1980-02-29 Lorenzini Sas Inst Biochim Processo per la preparazione della forma anidra dell acido 6, d, meno alfa aminofenilacetamido penicillanico
GB1494902A (en) * 1974-05-09 1977-12-14 Glaxo Lab Ltd Penicillins
IT1039495B (it) * 1975-06-26 1979-12-10 Dobfar Spa Procedimento per la preparazione di sostanze antibiotiche

Also Published As

Publication number Publication date
JPS5287191A (en) 1977-07-20
IT1053313B (it) 1981-08-31
GB1569427A (en) 1980-06-18
AU512150B2 (en) 1980-09-25
FR2338279B1 (fr) 1980-09-05
ES455026A1 (es) 1977-12-16
SE7700393L (sv) 1977-07-16
YU9277A (en) 1982-06-30
BE850382A (fr) 1977-07-14
AU2134077A (en) 1978-07-20
FR2338279A1 (fr) 1977-08-12
SE437989B (sv) 1985-03-25
DK13977A (da) 1977-07-16
ZA77195B (en) 1977-11-30
CH627182A5 (en) 1981-12-31
DE2701406A1 (de) 1977-07-21

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed