NL7908922A - Carboximidamide derivaten. - Google Patents

Carboximidamide derivaten. Download PDF

Info

Publication number
NL7908922A
NL7908922A NL7908922A NL7908922A NL7908922A NL 7908922 A NL7908922 A NL 7908922A NL 7908922 A NL7908922 A NL 7908922A NL 7908922 A NL7908922 A NL 7908922A NL 7908922 A NL7908922 A NL 7908922A
Authority
NL
Netherlands
Prior art keywords
hydroxy
indene
methanol
alkyl
dimethoxy
Prior art date
Application number
NL7908922A
Other languages
English (en)
Dutch (nl)
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Priority to NL7908922A priority Critical patent/NL7908922A/nl
Priority to ZA00807330A priority patent/ZA807330B/xx
Priority to EP80201118A priority patent/EP0030749B1/en
Priority to AT80201118T priority patent/ATE4454T1/de
Priority to IE2458/80A priority patent/IE50573B1/en
Priority to DE8080201118T priority patent/DE3064602D1/de
Priority to AU65023/80A priority patent/AU538801B2/en
Priority to PT72158A priority patent/PT72158B/pt
Priority to DK523080A priority patent/DK523080A/da
Priority to CA000366350A priority patent/CA1157478A/en
Priority to JP17445280A priority patent/JPS5692257A/ja
Priority to GR63610A priority patent/GR72506B/el
Priority to ES497642A priority patent/ES497642A0/es
Priority to FI803855A priority patent/FI803855A7/fi
Priority to HU802978A priority patent/HU185395B/hu
Publication of NL7908922A publication Critical patent/NL7908922A/nl
Priority to US06/452,194 priority patent/US4499105A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/16—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/22—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having nitrogen atoms of amidino groups further bound to nitrogen atoms, e.g. hydrazidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/16—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Medicines Containing Plant Substances (AREA)
NL7908922A 1979-12-12 1979-12-12 Carboximidamide derivaten. NL7908922A (nl)

Priority Applications (16)

Application Number Priority Date Filing Date Title
NL7908922A NL7908922A (nl) 1979-12-12 1979-12-12 Carboximidamide derivaten.
ZA00807330A ZA807330B (en) 1979-12-12 1980-11-24 Carboximidamide derivatives
EP80201118A EP0030749B1 (en) 1979-12-12 1980-11-26 Carboximidamide derivatives, a process for preparing them and pharmaceutical preparations containing same
AT80201118T ATE4454T1 (de) 1979-12-12 1980-11-26 Carboximidamid-derivate und diese enthaltende pharmazeutische praeparate, sowie ein verfahren zu ihrer herstellung.
IE2458/80A IE50573B1 (en) 1979-12-12 1980-11-26 Carboximidamide derivatives,a process for preparing them and pharmaceutical preparations containing same
DE8080201118T DE3064602D1 (en) 1979-12-12 1980-11-26 Carboximidamide derivatives, a process for preparing them and pharmaceutical preparations containing same
AU65023/80A AU538801B2 (en) 1979-12-12 1980-12-03 Carboximidamides
PT72158A PT72158B (en) 1979-12-12 1980-12-04 Carboximidamide derivatives
DK523080A DK523080A (da) 1979-12-12 1980-12-08 Carboximidamid-derivater
CA000366350A CA1157478A (en) 1979-12-12 1980-12-08 Carboximidamide derivatives
JP17445280A JPS5692257A (en) 1979-12-12 1980-12-10 Carboxyimidamide derivative
GR63610A GR72506B (da) 1979-12-12 1980-12-10
ES497642A ES497642A0 (es) 1979-12-12 1980-12-11 Un procedimiento para la preparacion de derivados de carboximidamida.
FI803855A FI803855A7 (fi) 1979-12-12 1980-12-11 Karboksimidiamidijohdannaisia.
HU802978A HU185395B (en) 1979-12-12 1980-12-12 Process for producing new carboximide-amide derivatives
US06/452,194 US4499105A (en) 1979-12-12 1982-12-28 Carboxyimidamide derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7908922 1979-12-12
NL7908922A NL7908922A (nl) 1979-12-12 1979-12-12 Carboximidamide derivaten.

Publications (1)

Publication Number Publication Date
NL7908922A true NL7908922A (nl) 1981-07-16

Family

ID=19834302

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7908922A NL7908922A (nl) 1979-12-12 1979-12-12 Carboximidamide derivaten.

Country Status (16)

Country Link
US (1) US4499105A (da)
EP (1) EP0030749B1 (da)
JP (1) JPS5692257A (da)
AT (1) ATE4454T1 (da)
AU (1) AU538801B2 (da)
CA (1) CA1157478A (da)
DE (1) DE3064602D1 (da)
DK (1) DK523080A (da)
ES (1) ES497642A0 (da)
FI (1) FI803855A7 (da)
GR (1) GR72506B (da)
HU (1) HU185395B (da)
IE (1) IE50573B1 (da)
NL (1) NL7908922A (da)
PT (1) PT72158B (da)
ZA (1) ZA807330B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661522A (en) * 1984-05-24 1987-04-28 Akzo N.V. Cycloalkane-indene-carboximidamide derivatives
US4634705A (en) * 1984-06-06 1987-01-06 Abbott Laboratories Adrenergic amidines
GB8508588D0 (en) * 1985-04-02 1985-05-09 Akzo Nv Indene & napthalene derivatives
FI81092C (fi) * 1986-05-15 1990-09-10 Farmos Oy Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat.
SE8605515D0 (sv) * 1986-12-22 1986-12-22 Astra Laekemedel Ab A liquid dosage form for oral administration of a pharmaceutically active substance
US5455274A (en) * 1992-12-09 1995-10-03 Ciba-Geigy Corporation Hydroxyamidine derivatives
PL180081B1 (pl) * 1993-08-12 2000-12-29 Astra Ab Nowe pochodne amidyny i sposób ich wytwarzania PL PL PL PL PL PL PL

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL33612A (en) * 1969-01-08 1973-06-29 Du Pont Amidoxime o-carbamates,their preparation and their use as antihypertensive agents
NL7310741A (nl) * 1973-08-03 1975-02-05 Akzo Nv Nieuwe n-hydroxy-amidine verbindingen.
DE2604196C3 (de) * 1976-02-04 1980-01-31 Merz & Co, 6000 Frankfurt Neue Amidine und diese enthaltende Arzneimittel

Also Published As

Publication number Publication date
ES8204415A1 (es) 1982-05-01
AU6502380A (en) 1981-06-18
ZA807330B (en) 1981-11-25
JPS5692257A (en) 1981-07-25
ES497642A0 (es) 1982-05-01
EP0030749A1 (en) 1981-06-24
ATE4454T1 (de) 1983-09-15
PT72158B (en) 1981-10-28
EP0030749B1 (en) 1983-08-17
IE802458L (en) 1981-06-12
FI803855L (fi) 1981-06-13
AU538801B2 (en) 1984-08-30
IE50573B1 (en) 1986-05-14
GR72506B (da) 1983-11-15
US4499105A (en) 1985-02-12
CA1157478A (en) 1983-11-22
DE3064602D1 (en) 1983-09-22
PT72158A (en) 1981-01-01
HU185395B (en) 1985-01-28
DK523080A (da) 1981-06-13
FI803855A7 (fi) 1981-06-13

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BV The patent application has lapsed