NL8320153A - Werkwijze voor het bereiden van 26,26,26,27,27,27,hexafluor-1alfa,25-dihydroxycholesterol. - Google Patents

Werkwijze voor het bereiden van 26,26,26,27,27,27,hexafluor-1alfa,25-dihydroxycholesterol. Download PDF

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Publication number
NL8320153A
NL8320153A NL8320153A NL8320153A NL8320153A NL 8320153 A NL8320153 A NL 8320153A NL 8320153 A NL8320153 A NL 8320153A NL 8320153 A NL8320153 A NL 8320153A NL 8320153 A NL8320153 A NL 8320153A
Authority
NL
Netherlands
Prior art keywords
diacetate
trinorcholest
triol
acyl
trinor
Prior art date
Application number
NL8320153A
Other languages
English (en)
Dutch (nl)
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of NL8320153A publication Critical patent/NL8320153A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nutrition Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8320153A 1982-05-26 1983-04-18 Werkwijze voor het bereiden van 26,26,26,27,27,27,hexafluor-1alfa,25-dihydroxycholesterol. NL8320153A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38205582 1982-05-26
US06/382,055 US4411833A (en) 1982-05-26 1982-05-26 Method for preparing 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxycholesterol

Publications (1)

Publication Number Publication Date
NL8320153A true NL8320153A (nl) 1984-04-02

Family

ID=23507359

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8320153A NL8320153A (nl) 1982-05-26 1983-04-18 Werkwijze voor het bereiden van 26,26,26,27,27,27,hexafluor-1alfa,25-dihydroxycholesterol.

Country Status (14)

Country Link
US (1) US4411833A (fr)
JP (2) JPH0742305B2 (fr)
AU (1) AU561182B2 (fr)
BE (1) BE896830A (fr)
CH (2) CH663212A5 (fr)
DE (1) DE3390016C2 (fr)
DK (1) DK168539B1 (fr)
FR (2) FR2527615B1 (fr)
GB (2) GB2121044B (fr)
IE (1) IE55022B1 (fr)
IL (1) IL68537A (fr)
IT (1) IT1203706B (fr)
NL (1) NL8320153A (fr)
WO (1) WO1983004256A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613594A (en) * 1984-11-16 1986-09-23 Hoffmann-La Roche Inc. Fluorinated vitamin D3 compounds
US4749710A (en) * 1985-05-01 1988-06-07 Hoffmann-La Roche Inc. Immunosuppressive agents
US4619920A (en) * 1985-09-16 1986-10-28 Wisconsin Alumni Research Foundation 26,26,26,27,27-pentafluoro-1α-hydroxy-27-methoxyvitamin D3
JPH0764804B2 (ja) * 1986-04-25 1995-07-12 住友製薬株式会社 活性型ビタミンｄ３のフッ素誘導体
WO1990009179A1 (fr) * 1989-02-16 1990-08-23 University Of Georgia Research Foundation, Inc. Traitement de la dyschondroplasie tibiale d'allien
US5366736A (en) * 1989-02-16 1994-11-22 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
US5316770A (en) * 1989-02-16 1994-05-31 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
AU6247194A (en) * 1993-02-19 1994-09-14 Wisconsin Alumni Research Foundation Use of 26,26,26,27,27,27-hexafluoro-1alpha,25-dihydroxycholecalcife rol for the treatment of calcium metabolism disorders
JP2009532458A (ja) * 2006-04-06 2009-09-10 ウイスコンシン アラムニ リサーチ ファンデーション ２−メチレン−１α−ヒドロキシ−１９，２１−ジノルビタミンＤ３類縁体およびその使用
NZ570712A (en) * 2006-04-06 2011-11-25 Wisconsin Alumni Res Found 2-methylene-1alpha-hydroxy-18,19,21-trinorvitamin D3 analogs and uses thereof
AU2007291005A1 (en) * 2006-04-06 2008-03-06 Wisconsin Alumni Research Foundation 19-nor-vitamin D analogs with 1,2,or 3,2 heterocyclic ring
CA2639585A1 (fr) * 2006-04-06 2007-10-06 Wisconsin Alumni Research Foundation 2-methylene-1.alpha.-25-dihydroxy-18,19,21-trinor-vitamine d3 et utilisations connexes
US8404666B2 (en) 2006-04-06 2013-03-26 Wisconsin Alumni Research Foundation 2-substituted-1α,25-dihydroxy-19,26,27-trinor vitamin D analogs and uses thereof
MX2008012912A (es) * 2006-04-06 2008-11-26 Wisconsin Alumni Res Found Analogos de 2-metilen-1a,25-dihidroxi-19,21-dinorvitamina d3 y sus usos.
NZ570816A (en) * 2006-04-10 2011-07-29 Wisconsin Alumni Res Found 1alpha-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin D compounds with a 1,1-dimethylpropyl side chain
AU2010208323B2 (en) 2009-01-27 2016-03-10 Berg Llc Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (fr) 2009-08-14 2019-05-22 Berg LLC Vitamine d3 et ses analogues pour le traitement de l'alopécie
SG10201709894RA (en) 2013-05-29 2018-01-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN113968888B (zh) * 2020-07-24 2023-06-27 上海医药工业研究院 一种胆甾衍生物的制备方法、其中间体及应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4183852A (en) * 1977-07-18 1980-01-15 Kaiser Emil T Process for preparing 25-hydroxycholesterol
LU80545A1 (de) * 1978-11-17 1980-06-05 Hoffmann La Roche Verfahren zur herstellung von 1a,3s-dihydroxy->5-steroiden
US4217279A (en) * 1978-12-18 1980-08-12 Kaiser Emil T Synthesis of steroids
JPS5598199A (en) * 1979-01-17 1980-07-25 Eisai Co Ltd Preparation of 25-hydroxy cholesta-1,4,6-trien-3-one
US4269777A (en) * 1979-05-21 1981-05-26 Wisconsin Alumni Research Foundation Isotopically labeled vitamin D derivatives and processes for preparing same
IL60270A0 (en) * 1979-06-14 1980-09-16 Diamond Shamrock Corp Preparation of 25-ydroxycholesterol
US4248791A (en) * 1980-02-04 1981-02-03 Wisconsin Alumni Research Foundation 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
US4360470A (en) * 1980-10-22 1982-11-23 Hoffmann-La Roche Inc. Process and intermediates for the synthesis of Vitamin D3 metabolites and chenodeoxycholic acid
US4358406A (en) * 1981-07-27 1982-11-09 Wisconsin Alumni Research Foundation 26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol and process for preparing same

Also Published As

Publication number Publication date
IL68537A0 (en) 1983-07-31
GB2121044B (en) 1986-01-02
DK32684D0 (da) 1984-01-25
BE896830A (fr) 1983-09-16
DK32684A (da) 1984-01-25
GB2121044A (en) 1983-12-14
US4411833A (en) 1983-10-25
WO1983004256A1 (fr) 1983-12-08
FR2533929B1 (fr) 1986-10-31
FR2527615B1 (fr) 1986-05-23
IL68537A (en) 1986-07-31
IT1203706B (it) 1989-02-15
IE55022B1 (en) 1990-04-25
AU1554283A (en) 1983-12-16
JPH0742305B2 (ja) 1995-05-10
DE3390016C2 (de) 1989-08-10
IT8321261A0 (it) 1983-05-24
DE3390016T1 (de) 1984-05-17
AU561182B2 (en) 1987-04-30
JPH0742306B2 (ja) 1995-05-10
CH663212A5 (de) 1987-11-30
GB8314612D0 (en) 1983-06-29
GB2140016A (en) 1984-11-21
IE831226L (en) 1983-11-26
JPH0578388A (ja) 1993-03-30
CH662572A5 (de) 1987-10-15
GB8415630D0 (en) 1984-07-25
DK168539B1 (da) 1994-04-18
JPH0578387A (ja) 1993-03-30
FR2533929A1 (fr) 1984-04-06
GB2140016B (en) 1986-01-02
FR2527615A1 (fr) 1983-12-02

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BI The patent application has been withdrawn