NO115214B - - Google Patents

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Info

Publication number: NO115214B
Authority: NO; Norway
Prior art keywords: oil; emulsion; thickened; oils; resin
Prior art date: 1963-06-28

Application number

NO153667A

Other languages

English (en)

Norwegian (no)

Inventor

R Boissonnas

S Guttmann

J Pless

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1963-06-28

Filing date

1964-06-16

Publication date

1968-09-02

1964-06-16 Application filed by Sandoz Ag filed Critical Sandoz Ag

1968-09-02 Publication of NO115214B publication Critical patent/NO115214B/no

Links

239000003921 oil Substances 0.000 claims description 34
235000019198 oils Nutrition 0.000 claims description 34
239000000839 emulsion Substances 0.000 claims description 31
PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims description 20
239000011347 resin Substances 0.000 claims description 20
229920005989 resin Polymers 0.000 claims description 20
229920001577 copolymer Polymers 0.000 claims description 17
239000000944 linseed oil Substances 0.000 claims description 7
235000021388 linseed oil Nutrition 0.000 claims description 7
238000004519 manufacturing process Methods 0.000 claims description 7
238000000034 method Methods 0.000 claims description 7
238000001035 drying Methods 0.000 claims description 6
235000014113 dietary fatty acids Nutrition 0.000 claims description 5
239000000194 fatty acid Substances 0.000 claims description 5
229930195729 fatty acid Natural products 0.000 claims description 5
150000004665 fatty acids Chemical class 0.000 claims description 5
125000005456 glyceride group Chemical group 0.000 claims description 4
239000000203 mixture Substances 0.000 claims description 4
-1 vinyl compound Chemical class 0.000 claims description 4
229920002554 vinyl polymer Polymers 0.000 claims description 4
239000004359 castor oil Substances 0.000 claims description 3
235000019438 castor oil Nutrition 0.000 claims description 3
ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 3
125000004432 carbon atom Chemical group C* 0.000 claims description 2
238000007720 emulsion polymerization reaction Methods 0.000 claims description 2
239000003549 soybean oil Substances 0.000 claims description 2
235000012424 soybean oil Nutrition 0.000 claims description 2
239000008240 homogeneous mixture Substances 0.000 claims 3
150000001735 carboxylic acids Chemical class 0.000 claims 1
239000000178 monomer Substances 0.000 description 11
239000000463 material Substances 0.000 description 8
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
239000003054 catalyst Substances 0.000 description 6
238000010438 heat treatment Methods 0.000 description 6
230000008719 thickening Effects 0.000 description 6
LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 5
NJWGQARXZDRHCD-UHFFFAOYSA-N 2-methylanthraquinone Chemical compound C1=CC=C2C(=O)C3=CC(C)=CC=C3C(=O)C2=C1 NJWGQARXZDRHCD-UHFFFAOYSA-N 0.000 description 4
239000011248 coating agent Substances 0.000 description 4
229940058020 2-amino-2-methyl-1-propanol Drugs 0.000 description 3
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 description 3
MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
239000003995 emulsifying agent Substances 0.000 description 3
239000002685 polymerization catalyst Substances 0.000 description 3
239000011148 porous material Substances 0.000 description 3
230000008569 process Effects 0.000 description 3
238000003756 stirring Methods 0.000 description 3
MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 2
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
UAHWPYUMFXYFJY-UHFFFAOYSA-N beta-myrcene Chemical compound CC(C)=CCCC(=C)C=C UAHWPYUMFXYFJY-UHFFFAOYSA-N 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
238000000576 coating method Methods 0.000 description 2
238000007334 copolymerization reaction Methods 0.000 description 2
239000000155 melt Substances 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
239000000126 substance Substances 0.000 description 2
UICXTANXZJJIBC-UHFFFAOYSA-N 1-(1-hydroperoxycyclohexyl)peroxycyclohexan-1-ol Chemical compound C1CCCCC1(O)OOC1(OO)CCCCC1 UICXTANXZJJIBC-UHFFFAOYSA-N 0.000 description 1
HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 1
KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical compound C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 description 1
241000270730 Alligator mississippiensis Species 0.000 description 1
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
239000004342 Benzoyl peroxide Substances 0.000 description 1
OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 description 1
235000013162 Cocos nucifera Nutrition 0.000 description 1
244000060011 Cocos nucifera Species 0.000 description 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 1
239000004908 Emulsion polymer Substances 0.000 description 1
235000019485 Safflower oil Nutrition 0.000 description 1
GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
239000002253 acid Substances 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
230000003679 aging effect Effects 0.000 description 1
VYBREYKSZAROCT-UHFFFAOYSA-N alpha-myrcene Natural products CC(=C)CCCC(=C)C=C VYBREYKSZAROCT-UHFFFAOYSA-N 0.000 description 1
150000001412 amines Chemical class 0.000 description 1
229910021529 ammonia Inorganic materials 0.000 description 1
125000000129 anionic group Chemical group 0.000 description 1
235000019400 benzoyl peroxide Nutrition 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
230000003197 catalytic effect Effects 0.000 description 1
230000008859 change Effects 0.000 description 1
238000004132 cross linking Methods 0.000 description 1
238000004945 emulsification Methods 0.000 description 1
229940013317 fish oils Drugs 0.000 description 1
239000011521 glass Substances 0.000 description 1
238000010348 incorporation Methods 0.000 description 1
229910052742 iron Inorganic materials 0.000 description 1
239000007788 liquid Substances 0.000 description 1
230000014759 maintenance of location Effects 0.000 description 1
238000002156 mixing Methods 0.000 description 1
REOJLIXKJWXUGB-UHFFFAOYSA-N mofebutazone Chemical group O=C1C(CCCC)C(=O)NN1C1=CC=CC=C1 REOJLIXKJWXUGB-UHFFFAOYSA-N 0.000 description 1
235000021313 oleic acid Nutrition 0.000 description 1
ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid group Chemical group C(CCCCCCC\C=C/CCCCCCCC)(=O)O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
150000002889 oleic acids Chemical class 0.000 description 1
239000002245 particle Substances 0.000 description 1
230000000149 penetrating effect Effects 0.000 description 1
239000004014 plasticizer Substances 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
238000006116 polymerization reaction Methods 0.000 description 1
HJWLCRVIBGQPNF-UHFFFAOYSA-N prop-2-enylbenzene Chemical compound C=CCC1=CC=CC=C1 HJWLCRVIBGQPNF-UHFFFAOYSA-N 0.000 description 1
239000002994 raw material Substances 0.000 description 1
230000009257 reactivity Effects 0.000 description 1
230000001105 regulatory effect Effects 0.000 description 1
239000003813 safflower oil Substances 0.000 description 1
235000005713 safflower oil Nutrition 0.000 description 1
239000000344 soap Substances 0.000 description 1
239000007787 solid Substances 0.000 description 1
229910001220 stainless steel Inorganic materials 0.000 description 1
239000010935 stainless steel Substances 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000006467 substitution reaction Methods 0.000 description 1
239000003784 tall oil Substances 0.000 description 1
239000002383 tung oil Substances 0.000 description 1
239000002966 varnish Substances 0.000 description 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
239000002023 wood Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/695—Corticotropin [ACTH]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

NO153667A 1963-06-28 1964-06-16 NO115214B (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH802163A CH439316A (de)	1963-06-28	1963-06-28	Verfahren zur Herstellung eines neuen Polypeptids

Publications (1)

Publication Number	Publication Date
NO115214B true NO115214B (fr)	1968-09-02

Family

ID=4333925

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO153667A NO115214B (fr)	1963-06-28	1964-06-16

Country Status (9)

Country	Link
AT (1)	AT266332B (fr)
BE (1)	BE649794A (fr)
CH (1)	CH439316A (fr)
ES (1)	ES301459A1 (fr)
FR (1)	FR3966M (fr)
GB (1)	GB1064263A (fr)
NL (1)	NL6407156A (fr)
NO (1)	NO115214B (fr)
OA (1)	OA01252A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN115137809A (zh) *	2021-03-31	2022-10-04	张菁	含有促肾上腺皮质激素及其衍生物的药物及其用途

1963
- 1963-06-28 CH CH802163A patent/CH439316A/de unknown
1964
- 1964-06-16 GB GB24840/64A patent/GB1064263A/en not_active Expired
- 1964-06-16 NO NO153667A patent/NO115214B/no unknown
- 1964-06-23 NL NL6407156A patent/NL6407156A/xx unknown
- 1964-06-26 BE BE649794A patent/BE649794A/xx unknown
- 1964-06-26 AT AT550864A patent/AT266332B/de active
- 1964-06-26 ES ES0301459A patent/ES301459A1/es not_active Expired
- 1964-09-25 FR FR989292A patent/FR3966M/fr not_active Expired
- 1964-12-31 OA OA51499A patent/OA01252A/fr unknown

Also Published As

Publication number	Publication date
ES301459A1 (es)	1965-01-16
FR3966M (fr)	1966-02-28
OA01252A (fr)	1969-01-25
BE649794A (fr)	1964-12-28
NL6407156A (fr)	1964-12-29
GB1064263A (en)	1967-04-05
CH439316A (de)	1967-07-15
AT266332B (de)	1968-11-11

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