NO144071C - Analogifremgangsmaate ved fremstilling av antihypertensivt aktive thienyl- og thietyl-ureaer - Google Patents

Analogifremgangsmaate ved fremstilling av antihypertensivt aktive thienyl- og thietyl-ureaer

Info

Publication number: NO144071C
Authority: NO; Norway
Prior art keywords: thietyl; urea; preparation; analogy procedure; antihypertensive active
Prior art date: 1974-04-17

Application number

NO751351A

Other languages

English (en)

Norwegian (no)

Other versions

NO144071B (no

NO751351L (fr

Inventor

Paul Edward Aldrich

Gilbert Harvey Berezin

Bruce Ivor Dittmar

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-04-17

Filing date

1975-04-16

Publication date

1981-06-17

1975-04-16 Application filed by Du Pont filed Critical Du Pont

1975-10-20 Publication of NO751351L publication Critical patent/NO751351L/no

1981-03-09 Publication of NO144071B publication Critical patent/NO144071B/no

1981-06-17 Publication of NO144071C publication Critical patent/NO144071C/no

Links

XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
230000003276 anti-hypertensive effect Effects 0.000 title 1
239000004202 carbamide Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
- C07D331/04—Four-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
- C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO751351A 1974-04-17 1975-04-16 Analogifremgangsmaate ved fremstilling av antihypertensivt aktive thienyl- og thietyl-ureaer NO144071C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46169974A	1974-04-17	1974-04-17
US05/555,307 US4009847A (en)	1974-04-17	1975-03-11	1-Tertiary-alkyl-3-(substituted thienyl)ureas and 1-tertiary-alkyl-3-(substituted thietyl)ureas as antihypertensive agents

Publications (3)

Publication Number	Publication Date
NO751351L NO751351L (fr)	1975-10-20
NO144071B NO144071B (no)	1981-03-09
NO144071C true NO144071C (no)	1981-06-17

Family

ID=27040095

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO751351A NO144071C (no)	1974-04-17	1975-04-16	Analogifremgangsmaate ved fremstilling av antihypertensivt aktive thienyl- og thietyl-ureaer

Country Status (21)

Country	Link
US (1)	US4009847A (fr)
JP (1)	JPS50148349A (fr)
AR (1)	AR208545A1 (fr)
CA (1)	CA1047042A (fr)
CH (1)	CH611292A5 (fr)
DD (1)	DD117223A5 (fr)
DE (1)	DE2516554A1 (fr)
DK (1)	DK164175A (fr)
ES (1)	ES436648A1 (fr)
FI (1)	FI751128A7 (fr)
FR (1)	FR2267773B1 (fr)
GB (1)	GB1461209A (fr)
HU (1)	HU173052B (fr)
IE (1)	IE41143B1 (fr)
IL (1)	IL47095A (fr)
LU (1)	LU72306A1 (fr)
NL (1)	NL7504570A (fr)
NO (1)	NO144071C (fr)
PH (1)	PH11722A (fr)
SE (1)	SE417965B (fr)
YU (1)	YU96075A (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4156738A (en) *	1977-10-07	1979-05-29	E. I. Du Pont De Nemours And Company	Ureidonitriles useful as antihypertensives
US6187799B1 (en) *	1997-05-23	2001-02-13	Onyx Pharmaceuticals	Inhibition of raf kinase activity using aryl ureas
US6344476B1 (en) *	1997-05-23	2002-02-05	Bayer Corporation	Inhibition of p38 kinase activity by aryl ureas
US7517880B2 (en)	1997-12-22	2009-04-14	Bayer Pharmaceuticals Corporation	Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
US7329670B1 (en)	1997-12-22	2008-02-12	Bayer Pharmaceuticals Corporation	Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
US20080300281A1 (en) *	1997-12-22	2008-12-04	Jacques Dumas	Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
US20080269265A1 (en) *	1998-12-22	2008-10-30	Scott Miller	Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
CA2359244C (fr) *	1999-01-13	2013-10-08	Bayer Healthcare Llc	Diphenyle urees a substitution .omega.-carboxy aryle en tant qu'inhibiteurs de la kinase p38
US7351834B1 (en) *	1999-01-13	2008-04-01	Bayer Pharmaceuticals Corporation	ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US8124630B2 (en)	1999-01-13	2012-02-28	Bayer Healthcare Llc	ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
EP1140840B1 (fr)	1999-01-13	2006-03-22	Bayer Pharmaceuticals Corp.	Diphenylurees a substituants -g(v)-carboxyaryles, inhibitrices de kinase raf
US7928239B2 (en)	1999-01-13	2011-04-19	Bayer Healthcare Llc	Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
US7235576B1 (en)	2001-01-12	2007-06-26	Bayer Pharmaceuticals Corporation	Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US7371763B2 (en) *	2001-04-20	2008-05-13	Bayer Pharmaceuticals Corporation	Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
AU2002351196A1 (en) *	2001-12-03	2003-06-17	Bayer Pharmaceuticals Corporation	Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers
US20080108672A1 (en) *	2002-01-11	2008-05-08	Bernd Riedl	Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
US20030216396A1 (en) *	2002-02-11	2003-11-20	Bayer Corporation	Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors
WO2003068223A1 (fr) *	2002-02-11	2003-08-21	Bayer Corporation	Urees aryliques a kinase de raf et activite inhibitrice d'angiogenese
SI1580188T1 (sl) *	2002-02-11	2012-02-29	Bayer Healthcare Llc	Aril sečnine kot kinazni inhibitorji
EP2324825A1 (fr) *	2002-02-11	2011-05-25	Bayer Healthcare LLC	Arylurées dotées d'une activité d'inhibition de l'angiogenèse
UY28213A1 (es) *	2003-02-28	2004-09-30	Bayer Pharmaceuticals Corp	Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos.
DE602004007382T2 (de) *	2003-05-20	2008-04-17	Bayer Pharmaceuticals Corp., West Haven	Diaryl-harnstoffe für durch pdgfr vermittelte krankheiten
DK1663978T3 (da) *	2003-07-23	2008-04-07	Bayer Pharmaceuticals Corp	Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser
JP2007535565A (ja) *	2004-04-30	2007-12-06	バイエルファーマシューティカルスコーポレーション	癌の治療に有用な置換ピラゾリル尿素誘導体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH452475A (de) *	1965-05-20	1968-05-31	Bayer Ag	Verfahren zum Färben und Bedrucken von synthetischem Textilmaterial mit Anthrachinonfarbstoffen

1975
- 1975-03-11 US US05/555,307 patent/US4009847A/en not_active Expired - Lifetime
- 1975-03-26 SE SE7503523A patent/SE417965B/xx unknown
- 1975-04-15 IL IL47095A patent/IL47095A/xx unknown
- 1975-04-15 CA CA224,634A patent/CA1047042A/fr not_active Expired
- 1975-04-16 PH PH17061A patent/PH11722A/en unknown
- 1975-04-16 HU HU75DU237A patent/HU173052B/hu unknown
- 1975-04-16 DK DK164175A patent/DK164175A/da not_active IP Right Cessation
- 1975-04-16 ES ES436648A patent/ES436648A1/es not_active Expired
- 1975-04-16 GB GB1567175A patent/GB1461209A/en not_active Expired
- 1975-04-16 DD DD185482A patent/DD117223A5/xx unknown
- 1975-04-16 DE DE19752516554 patent/DE2516554A1/de not_active Withdrawn
- 1975-04-16 NO NO751351A patent/NO144071C/no unknown
- 1975-04-16 FI FI751128A patent/FI751128A7/fi not_active Application Discontinuation
- 1975-04-16 YU YU00960/75A patent/YU96075A/xx unknown
- 1975-04-16 FR FR7511796A patent/FR2267773B1/fr not_active Expired
- 1975-04-16 AR AR258396A patent/AR208545A1/es active
- 1975-04-17 CH CH494875A patent/CH611292A5/xx not_active IP Right Cessation
- 1975-04-17 LU LU72306A patent/LU72306A1/xx unknown
- 1975-04-17 NL NL7504570A patent/NL7504570A/xx not_active Application Discontinuation
- 1975-04-17 IE IE865/75A patent/IE41143B1/xx unknown
- 1975-04-17 JP JP50045924A patent/JPS50148349A/ja active Pending

Also Published As

Publication number	Publication date
CA1047042A (fr)	1979-01-23
IL47095A0 (en)	1975-06-25
FI751128A7 (fr)	1975-10-18
HU173052B (hu)	1979-02-28
LU72306A1 (fr)	1976-03-17
YU96075A (en)	1983-04-27
SE417965B (sv)	1981-04-27
JPS50148349A (fr)	1975-11-27
IL47095A (en)	1978-03-10
AR208545A1 (es)	1977-02-15
IE41143L (en)	1975-10-17
PH11722A (en)	1978-05-30
NO144071B (no)	1981-03-09
DK164175A (da)	1975-10-18
NO751351L (fr)	1975-10-20
ES436648A1 (es)	1977-08-01
SE7503523L (sv)	1975-10-20
NL7504570A (nl)	1975-10-21
DE2516554A1 (de)	1975-10-30
FR2267773B1 (fr)	1978-08-18
US4009847A (en)	1977-03-01
CH611292A5 (fr)	1979-05-31
AU8013575A (en)	1976-10-21
FR2267773A1 (fr)	1975-11-14
GB1461209A (en)	1977-01-13
DD117223A5 (fr)	1976-01-05
IE41143B1 (en)	1979-10-24

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