NO151367C - Analogifremgangsmaate for fremstilling av terapeutisk aktive syreaddisjonsslater av 16beta-monokvaternaere ammoniumderivater av 2beta,16beta-bis-piperidino-5alfa-androstaner - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive syreaddisjonsslater av 16beta-monokvaternaere ammoniumderivater av 2beta,16beta-bis-piperidino-5alfa-androstaner

Info

Publication number
NO151367C
NO151367C NO792810A NO792810A NO151367C NO 151367 C NO151367 C NO 151367C NO 792810 A NO792810 A NO 792810A NO 792810 A NO792810 A NO 792810A NO 151367 C NO151367 C NO 151367C
Authority
NO
Norway
Prior art keywords
16beta
monoquaterary
5alfa
2beta
androstanes
Prior art date
Application number
NO792810A
Other languages
English (en)
Norwegian (no)
Other versions
NO151367B (no
NO792810L (no
Inventor
Ian Craig Carlyle
Thomas Sleigh
David Samuel Savage
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of NO792810L publication Critical patent/NO792810L/no
Publication of NO151367B publication Critical patent/NO151367B/no
Publication of NO151367C publication Critical patent/NO151367C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
NO792810A 1978-09-05 1979-08-29 Analogifremgangsmaate for fremstilling av terapeutisk aktive syreaddisjonsslater av 16beta-monokvaternaere ammoniumderivater av 2beta,16beta-bis-piperidino-5alfa-androstaner NO151367C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7835667 1978-09-05

Publications (3)

Publication Number Publication Date
NO792810L NO792810L (no) 1980-03-06
NO151367B NO151367B (no) 1984-12-17
NO151367C true NO151367C (no) 1985-03-27

Family

ID=10499453

Family Applications (1)

Application Number Title Priority Date Filing Date
NO792810A NO151367C (no) 1978-09-05 1979-08-29 Analogifremgangsmaate for fremstilling av terapeutisk aktive syreaddisjonsslater av 16beta-monokvaternaere ammoniumderivater av 2beta,16beta-bis-piperidino-5alfa-androstaner

Country Status (20)

Country Link
US (2) US4237126A (fr)
EP (1) EP0008824B1 (fr)
JP (1) JPS5535098A (fr)
AR (1) AR228728A1 (fr)
AT (1) ATE921T1 (fr)
AU (1) AU526270B2 (fr)
CA (1) CA1134813A (fr)
DE (1) DE2962627D1 (fr)
DK (1) DK159119C (fr)
ES (1) ES483894A1 (fr)
FI (1) FI66881C (fr)
GR (1) GR72520B (fr)
HU (1) HU181847B (fr)
IE (1) IE50376B1 (fr)
IL (1) IL58080A (fr)
NO (1) NO151367C (fr)
NZ (1) NZ191462A (fr)
PH (1) PH16041A (fr)
PT (1) PT70126A (fr)
ZA (1) ZA794371B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE50675B1 (en) * 1979-12-12 1986-06-11 Akzo Nv Bis-and mono-quaternary ammonium derivatives of 2beta,16beta-dipiperidino-5alpha-androstanes,processes for their preparation and pharmaceutical preparations
IE53463B1 (en) * 1981-06-15 1988-11-23 Akzo Nv Mono-and bisquaternary ammonium derivatives of 2 beta,16 beta-d-amino-5 alpha-androstane derivatives and pharmaceutical preparations containing same
GB8709565D0 (en) * 1987-04-23 1987-05-28 Akzo Nv 2beta,16beta-diaminoandrostanes
US5238957A (en) * 1988-07-07 1993-08-24 Presidenza Del Consiglio Dei Ministri-Uffico Del Ministro Per Il Coordinamento Delle Iniziative Per La Ricerca Scientifica E Tecnologica Esters of 2,2-dimethyl-cyclopropane-carboxylic acid
US5418226A (en) * 1992-04-22 1995-05-23 Akzo N.V. Monoquaternary 2,16-bispiperidinylandrostane derivatives
HU210076B (en) * 1992-11-02 1995-01-30 Tuba Process for producing androstane derivatives substituted with quaternisaeted amino group in 16-position and for producing pharmaceutical compositions containing them
GB9302455D0 (en) * 1993-02-08 1993-03-24 Lab Inpharm N V Process for preparing a pharmaceutical preparation having neuromuscular blocking activity
US5767112A (en) * 1994-10-21 1998-06-16 Poli Industria Chimica, S.P.A. Muscle relaxant pharmaceutical compositions
US5553456A (en) * 1995-05-17 1996-09-10 Ramco, Inc. Clathrate freeze desalination apparatus and method
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
HU0402017D0 (en) * 2004-10-07 2004-12-28 Richter Gedeon Vegyeszet Environment-friend process for the synthesis of quaternary ammonio-steroids
WO2006038047A1 (fr) * 2004-10-07 2006-04-13 Richter Gedeon Vegyészeti Gyár Rt. Procede non polluant de synthese d'ammonio-steroides quaternaires
CA2605138A1 (fr) * 2005-04-15 2006-10-26 Lyotropic Therapeutics, Inc. Preparation d'agents bloquants neuromusculaires a base d'ammonium quaternaire
DE102005030423A1 (de) * 2005-06-30 2007-01-04 Inresa Arzneimittel Gmbh Neue Formulierung für Vecuroniumbromid
JP5213137B2 (ja) 2006-12-06 2013-06-19 コーネル リサーチ ファウンデーション， インコーポレイテッド 中程度の持続時間の神経筋遮断剤およびそのアンタゴニスト
WO2010107488A1 (fr) 2009-03-17 2010-09-23 Cornell University Agents de blocage neuromusculaires non dépolarisants réversibles et leur méthode
CN102573794B (zh) 2009-08-19 2017-03-15 康奈尔大学 供生理注射用的半胱氨酸
WO2022078483A1 (fr) * 2020-10-15 2022-04-21 江苏恩华络康药物研发有限公司 Composé stéroïde d'ammonium quaternaire, son procédé de préparation, sa préparation et son utilisation
CN116925171B (zh) * 2023-07-10 2025-06-27 时森海(杭州)医药科技有限公司 含环丙甲基甾体类季铵盐化合物、中间体及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
GB1454749A (en) * 1972-11-29 1976-11-03 Akzo Nv 2beta, 16beta-diamino-androstanes and their preparation
HU171166B (hu) * 1975-07-15 1977-11-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh ehpoksi-androstanov
US4177190A (en) * 1975-08-01 1979-12-04 Richter Gedeon Vegyeszeti Gyar Rt. Diamino-androstanes and a process for the preparation of the said compounds
HU172522B (hu) * 1975-08-01 1978-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 2beta, 16beta-diamino-androstana i ikh chetvertichnykh solej

Also Published As

Publication number Publication date
EP0008824A1 (fr) 1980-03-19
ZA794371B (en) 1980-08-27
IL58080A0 (en) 1979-12-30
DE2962627D1 (en) 1982-06-09
HU181847B (en) 1983-11-28
GR72520B (fr) 1983-11-16
PH16041A (en) 1983-06-02
JPS5535098A (en) 1980-03-11
AR228728A1 (es) 1983-04-15
EP0008824B1 (fr) 1982-04-28
IL58080A (en) 1982-12-31
FI792745A7 (fi) 1980-03-06
FI66881B (fi) 1984-08-31
NO151367B (no) 1984-12-17
AU526270B2 (en) 1982-12-23
JPS6245879B2 (fr) 1987-09-29
US4297351A (en) 1981-10-27
DK159119C (da) 1991-03-11
IE50376B1 (en) 1986-04-16
NO792810L (no) 1980-03-06
ES483894A1 (es) 1980-09-01
IE791593L (en) 1980-03-05
CA1134813A (fr) 1982-11-02
FI66881C (fi) 1984-12-10
DK159119B (da) 1990-09-03
DK361779A (da) 1980-03-06
PT70126A (en) 1979-09-01
NZ191462A (en) 1982-03-16
ATE921T1 (de) 1982-05-15
US4237126A (en) 1980-12-02
AU5034879A (en) 1980-03-13

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