NO151463C - Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater

Info

Publication number: NO151463C
Authority: NO; Norway
Prior art keywords: preparation; therapeutic active; analogy procedure; chinazoline derivatives; chinazoline
Prior art date: 1978-02-06

Application number

NO790358A

Other languages

English (en)

Norwegian (no)

Other versions

NO151463B (no

NO790358L (no

Inventor

Philippe Michel Jacque Manoury

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-02-06

Filing date

1979-02-05

Publication date

1985-04-17

1979-02-05 Application filed by Synthelabo filed Critical Synthelabo

1979-08-07 Publication of NO790358L publication Critical patent/NO790358L/no

1985-01-02 Publication of NO151463B publication Critical patent/NO151463B/no

1985-04-17 Publication of NO151463C publication Critical patent/NO151463C/no

Links

230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO790358A 1978-02-06 1979-02-05 Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater NO151463C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR7803175A FR2421888A1 (fr)	1978-02-06	1978-02-06	Amides d'alkylene-diamines et leur application en therapeutique
FR7836819A FR2445323A2 (fr)	1978-02-06	1978-12-29	Amides d'alkylenediamines et leur application en therapeutique

Publications (3)

Publication Number	Publication Date
NO790358L NO790358L (no)	1979-08-07
NO151463B NO151463B (no)	1985-01-02
NO151463C true NO151463C (no)	1985-04-17

Family

ID=26220430

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO790358A NO151463C (no)	1978-02-06	1979-02-05	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater

Country Status (23)

Country	Link
US (1)	US4315007A (fr)
JP (1)	JPS6023114B2 (fr)
AT (1)	AT365176B (fr)
AU (1)	AU521524B2 (fr)
BE (1)	BE873909A (fr)
CA (1)	CA1102330A (fr)
CH (1)	CH637122A5 (fr)
DE (1)	DE2904445C2 (fr)
DK (1)	DK159316C (fr)
ES (1)	ES477457A1 (fr)
FI (1)	FI66861C (fr)
FR (2)	FR2421888A1 (fr)
GB (1)	GB2013679B (fr)
GR (1)	GR66846B (fr)
IE (1)	IE47812B1 (fr)
IL (1)	IL56578A (fr)
IT (1)	IT1192347B (fr)
LU (1)	LU80880A1 (fr)
NL (2)	NL181482C (fr)
NO (1)	NO151463C (fr)
NZ (1)	NZ189553A (fr)
PT (1)	PT69178A (fr)
SE (1)	SE449360B (fr)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2466462A2 (fr) *	1978-02-06	1981-04-10	Synthelabo	Derives d'alkylenediamines, leur preparation et leur application en therapeutique
EP0105838B1 (fr) *	1982-09-30	1989-06-21	William John Louis	Dérivés amino-3-propoxy-phényliques, leur préparation et compositions pharmaceutiques les contenant
FR2577803B1 (fr) *	1985-02-26	1987-04-03	Synthelabo	Compositions pharmaceutiques a base de nifedipine et d'alfuzosine
FR2570275B1 (fr) *	1984-09-14	1986-11-21	Synthelabo	Compositions pharmaceutiques a base de diltiazem et d'alfusozine
FR2577804B1 (fr) *	1985-02-26	1987-03-27	Synthelabo	Compositions pharmaceutiques a base de verapamil et d'alfuzosine
EP0189336A1 (fr) *	1985-01-18	1986-07-30	Synthelabo	Compositions pharmaceutiques contenant un alpha-bloquant et un antagoniste du calcium
FR2582513B1 (fr) *	1985-05-28	1988-08-05	Synthelabo	Compositions pharmaceutiques contenant de l'alfuzosine
LU86672A1 (fr) *	1986-11-19	1988-06-13	Oreal	Composition pour induire et stimuler la croissance des cheveux et diminuer la chute a base de derives d'alkylene diamino quinazoline
YU70890A (en) *	1989-04-21	1992-05-28	Egyt Gyogyszervegyeszeti Gyar	Process for obtaining quinazoline derivatives
IL101243A (en) *	1991-03-20	1999-12-22	Merck & Co Inc	Pharmaceutical preparations for the treatment of benign prostatic hyperplasia containing steroid history
FR2694495B1 (fr) *	1992-08-05	1994-09-23	Synthelabo	Préparation pharmaceutique transdermique contenant de l'alfuzosine.
JPH07206857A (ja) *	1993-12-28	1995-08-08	Synthelabo Sa	アルフゾシン塩酸塩の二水和物
FR2717388B1 (fr) *	1994-03-21	1996-11-22	Synthelabo	Formes galéniques à libération prolongée du chlorhydrate d'alfuzosine.
US6313294B1 (en)	1998-02-04	2001-11-06	Development Center For Biotechnology	Process for preparing amides
KR100648869B1 (ko)	1998-09-30	2007-02-28	다케다 야쿠힌 고교 가부시키가이샤	방광 배출력 개선제
WO2001068615A1 (fr) *	2000-03-13	2001-09-20	Chemrx Advanced Technologies, Inc.	Synthese de la quinazoline
US20020065286A1 (en) *	2000-08-21	2002-05-30	Davies Michael John	Treatment of wounds
US20020091129A1 (en) *	2000-11-20	2002-07-11	Mitradev Boolell	Treatment of premature ejaculation
GB0130219D0 (en) *	2001-12-18	2002-02-06	Pfizer Ltd	Compounds for the treatment of sexual dysfunction
US20030229001A1 (en) *	2002-01-31	2003-12-11	Pfizer Inc.	Treatment of male sexual dysfunction
GB0219961D0 (en)	2002-08-28	2002-10-02	Pfizer Ltd	Oxytocin inhibitors
US7323462B2 (en) *	2002-12-10	2008-01-29	Pfizer Inc.	Morpholine dopamine agonists
CA2451267A1 (fr) *	2002-12-13	2004-06-13	Warner-Lambert Company Llc	Utilisations pharmaceutiques de ligands alpha2delta
WO2004054560A1 (fr)	2002-12-13	2004-07-01	Warner-Lambert Company Llc	Ligand alpha-2-delta pour traiter des symptomes des voies urinaires inferieures
PA8597401A1 (es) *	2003-03-14	2005-05-24	Pfizer	Derivados del acido 3-(1-[3-(1,3-benzotiazol-6-il) propilcarbamoil] cicloalquil) propanoico como inhibidores de nep
US20040220186A1 (en) *	2003-04-30	2004-11-04	Pfizer Inc.	PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease
US20050065158A1 (en) *	2003-07-16	2005-03-24	Pfizer Inc.	Treatment of sexual dysfunction
US7291640B2 (en) *	2003-09-22	2007-11-06	Pfizer Inc.	Substituted triazole derivatives as oxytocin antagonists
US20050267096A1 (en) *	2004-05-26	2005-12-01	Pfizer Inc	New indazole and indolone derivatives and their use pharmaceuticals
US20050288270A1 (en) *	2004-05-27	2005-12-29	Pfizer Inc	New aminopyridine derivatives and their use as pharmaceuticals
PL1789412T3 (pl) *	2004-09-16	2008-10-31	Hetero Drugs Ltd	Krystaliczna zasada alfuzosyny
JP2008533193A (ja) *	2005-03-21	2008-08-21	ファイザー・リミテッド	オキシトシン拮抗薬としての置換トリアゾール誘導体
WO2006100557A1 (fr) *	2005-03-21	2006-09-28	Pfizer Limited	Derives de triazole substitues en tant qu'antagonistes d'oxytocine
EP1917257A1 (fr) *	2005-08-10	2008-05-07	Pfizer Limited	Derives de triazole substitues en tant qu'antagonistes d'oxytocine
US20070066824A1 (en) *	2005-09-22	2007-03-22	Anumula Raghupathi R	Preparation of alfuzosin
US20070105880A1 (en) *	2005-11-08	2007-05-10	Torrent Pharmaceuticals Limited	Process for the preparation of alfuzosin
WO2007074364A1 (fr) *	2005-12-26	2007-07-05	Aurobindo Pharma Limited	Procede ameliore pour la preparation d’un medicament contre la dysurie
CN100564376C (zh) *	2006-09-19	2009-12-02	浙江华纳药业有限公司	阿夫唑嗪的制备方法
CN101190890B (zh) *	2006-11-30	2011-04-27	江苏豪森药业股份有限公司	5-[(2r)-[2-[2-[2-(2,2,2-三氟乙氧基)苯氧基]乙基]氨基]丙基]-2-甲氧基苯磺酰胺
US20100092556A1 (en) *	2006-12-11	2010-04-15	Kristin Arnold	Alfuzosin formulations, methods of making, and methods of use
WO2008073388A2 (fr) *	2006-12-11	2008-06-19	Mutual Pharmaceutical Company, Inc.	Formulations d'alfuzosine, procédés de fabrication et procédés d'utilisation de celles-ci
WO2008152514A2 (fr)	2007-05-04	2008-12-18	Actavis Group Ptc Ehf	Procédé de préparation de l'alfuzosine et de ses sels
WO2009001369A1 (fr) *	2007-06-22	2008-12-31	Alembic Limited	Procédé perfectionné pour la préparation de chlorhydrate d'alfuzosine
WO2009007987A1 (fr) *	2007-07-11	2009-01-15	Alembic Limited	Procédé amélioré pour la préparation d'alfuzosine et de son nouveau polymorphe
US8716476B2 (en) *	2007-08-02	2014-05-06	Cipla Limited	Process for the preparation of alfuzosin hydrochloride
US20090076043A1 (en) *	2007-09-19	2009-03-19	Protia, Llc	Deuterium-enriched alfuzosin
US20100183717A1 (en) *	2009-01-16	2010-07-22	Kristin Arnold	Controlled-release formulations
CN107998090A (zh) *	2017-12-30	2018-05-08	威海贯标信息科技有限公司	一种阿夫唑嗪片组合物
CN113801069B (zh) *	2020-06-15	2024-03-15	鲁南制药集团股份有限公司	一种盐酸阿夫唑嗪中间体化合物
CN114573569B (zh) *	2022-03-30	2023-07-04	邦恩泰(山东)生物医药科技集团股份有限公司	一种异喹啉类化合物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3635979A (en) *	1969-09-29	1972-01-18	Pfizer	Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
US4026894A (en) *	1975-10-14	1977-05-31	Abbott Laboratories	Antihypertensive agents
US4060615A (en) *	1976-02-18	1977-11-29	Mead Johnson & Company	2-Piperazinyl-6,7-dimethoxyquinazolines
FR2350101A1 (fr) *	1976-05-07	1977-12-02	Synthelabo	Nouvelles guanidines cyclisees
DK140695C (da) *	1976-05-07	1980-05-12	Synthelabo	Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf
FR2362630A1 (fr) *	1976-08-24	1978-03-24	Synthelabo	Derives d'alkylenediamines
FR2389613A2 (en) *	1977-05-05	1978-12-01	Synthelabo	Antihypertensive 4-amino-6,7-di:methoxy-quinazolyl alkylene di:amine - prepd. from a 2-halo-quinazoline and an alkylene di:amine

1978
- 1978-02-06 FR FR7803175A patent/FR2421888A1/fr active Granted
- 1978-12-29 FR FR7836819A patent/FR2445323A2/fr active Granted
1979
- 1979-02-02 DK DK046079A patent/DK159316C/da not_active IP Right Cessation
- 1979-02-02 IL IL56578A patent/IL56578A/xx unknown
- 1979-02-02 NZ NZ189553A patent/NZ189553A/xx unknown
- 1979-02-02 AU AU43895/79A patent/AU521524B2/en not_active Expired
- 1979-02-02 GR GR50581A patent/GR66846B/el unknown
- 1979-02-02 BE BE0/193248A patent/BE873909A/fr not_active IP Right Cessation
- 1979-02-05 JP JP54012737A patent/JPS6023114B2/ja not_active Expired
- 1979-02-05 FI FI790369A patent/FI66861C/fi not_active IP Right Cessation
- 1979-02-05 AT AT0084279A patent/AT365176B/de not_active IP Right Cessation
- 1979-02-05 NO NO790358A patent/NO151463C/no unknown
- 1979-02-05 CA CA320,864A patent/CA1102330A/fr not_active Expired
- 1979-02-05 SE SE7900987A patent/SE449360B/sv not_active IP Right Cessation
- 1979-02-05 CH CH112079A patent/CH637122A5/fr not_active IP Right Cessation
- 1979-02-05 PT PT7969178A patent/PT69178A/fr active IP Right Revival
- 1979-02-05 IT IT19908/79A patent/IT1192347B/it active Protection Beyond IP Right Term
- 1979-02-05 ES ES477457A patent/ES477457A1/es not_active Expired
- 1979-02-05 LU LU80880A patent/LU80880A1/fr unknown
- 1979-02-05 IE IE210/79A patent/IE47812B1/en not_active IP Right Cessation
- 1979-02-06 DE DE2904445A patent/DE2904445C2/de not_active Expired
- 1979-02-06 NL NLAANVRAGE7900917,A patent/NL181482C/xx not_active IP Right Cessation
- 1979-02-06 GB GB79403279A patent/GB2013679B/en not_active Expired
- 1979-12-10 US US06/099,622 patent/US4315007A/en not_active Expired - Lifetime
1993
- 1993-05-28 NL NL930043C patent/NL930043I2/nl unknown

Also Published As

Publication number	Publication date
IL56578A (en)	1983-02-23
IE47812B1 (en)	1984-06-27
CA1102330A (fr)	1981-06-02
IT1192347B (it)	1988-03-31
DK159316B (da)	1990-10-01
FI66861C (fi)	1984-12-10
ATA84279A (de)	1981-05-15
AU521524B2 (en)	1982-04-08
FR2421888B1 (fr)	1980-09-26
BE873909A (fr)	1979-08-02
SE7900987L (sv)	1979-08-07
CH637122A5 (fr)	1983-07-15
US4315007A (en)	1982-02-09
GB2013679B (en)	1982-09-02
DK159316C (da)	1991-03-04
DE2904445C2 (de)	1986-10-30
FI66861B (fi)	1984-08-31
SE449360B (sv)	1987-04-27
NO151463B (no)	1985-01-02
NZ189553A (en)	1981-05-01
NO790358L (no)	1979-08-07
JPS54117487A (en)	1979-09-12
NL181482B (nl)	1987-04-01
FR2445323B2 (fr)	1981-11-27
NL7900917A (nl)	1979-08-08
LU80880A1 (fr)	1980-09-24
FR2421888A1 (fr)	1979-11-02
GR66846B (fr)	1981-05-05
PT69178A (fr)	1979-03-01
FR2445323A2 (fr)	1980-07-25
NL930043I1 (nl)	1993-08-02
JPS6023114B2 (ja)	1985-06-05
AT365176B (de)	1981-12-28
IL56578A0 (en)	1979-05-31
FI790369A7 (fi)	1979-08-07
ES477457A1 (es)	1979-10-16
GB2013679A (en)	1979-08-15
DE2904445A1 (de)	1979-08-16
IT7919908A0 (it)	1979-02-05
NL181482C (nl)	1987-09-01
NL930043I2 (nl)	1993-11-16
IE790210L (en)	1979-08-06
DK46079A (da)	1979-08-07
AU4389579A (en)	1979-08-16

Publication	Publication Date	Title
NO151321C (no)	1985-03-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater
NO151463C (no)	1985-04-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater
NO147243C (no)	1983-03-02	Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalanderivater
NO152215C (no)	1985-08-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive 4,5-diaryl-2-nitroimidazoler
NO149102C (no)	1984-02-15	Analogifremgangsmaate for fremstilling av terapeutisk aktive trans-4-fenyl-1,2,3,4-tetrahydro-1-naftalenamin-derivater
NO151411C (no)	1985-04-10	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-aryloksy-2-hydroksy-3-alkylenaminopropan-derivater
NO151546C (no)	1985-05-02	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoner
NO153569C (no)	1986-05-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive merkaptoacetyl-prolin-derivater.
NO800881L (no)	1980-09-29	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolonderivater
NO150360C (no)	1984-10-03	Analogifremgangsmaate for fremstilling av terapeutisk aktive merkaptoacyldipeptider
NO814136L (no)	1982-06-07	Analogifremgangsmaate for fremstilling av terapeutisk aktive 8-arylalkyl-3-fenyl-3-notropanol-derivater
NO148777C (no)	1984-01-25	Analogifremgangsmaate for fremstilling av terapeutisk aktive antrakinon-derivater
NO151239C (no)	1985-03-06	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-fenyliminoimidazolidiner
NO149313C (no)	1984-03-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridobenzodiazepiner
NO149037C (no)	1984-02-01	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridobenzodiazepiner
NO151285C (no)	1985-03-13	Analogifremgangsmaate for fremstilling av terapeutisk aktive di-o-n-alkyl-glycerolderivater
NO148488C (no)	1983-10-19	Analogifremgangsmaate til fremstilling av terapeutisk aktive acyl-benzimidazol-2-derivater
NO146863C (no)	1982-12-22	Analogifremgangsmaate til fremstilling av terapeutisk aktive alkyltiofenoksyalkylaminer
NO813821L (no)	1982-05-13	Analogifremgangsmaate for fremstilling av terapeutisk aktive indolinon-derivater
NO151660C (no)	1985-05-15	Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazolderivater.
NO151008C (no)	1985-01-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive nitroforbindelser
NO152172C (no)	1985-08-14	Analogifremgangsmaate for fremstilling av terapeutisk aktive spiro-kinolyl-hydantoin-derivater
NO147273C (no)	1983-03-09	Analogifremgangsmaate til fremstilling av terapeutisk aktive cykloheksadien-derivater
NO152839C (no)	1985-11-27	Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater.
NO152556C (no)	1985-10-16	Analogifremgangsmaate for fremstilling av terapeutisk aktive antracen-biskarbonylhydrazoner