NO161741C - Analogifremgangsm te ved fremstilling av pyrrolo(1,2-a)imidazoler eller imidazo(1,2-a)pyridiner. - Google Patents

Analogifremgangsm te ved fremstilling av pyrrolo(1,2-a)imidazoler eller imidazo(1,2-a)pyridiner.

Info

Publication number: NO161741C
Authority: NO; Norway
Prior art keywords: imidazo; pyrrolo; pyridines; imidazoles; preparation
Prior art date: 1983-07-29

Application number

NO843053A

Other languages

English (en)

Norwegian (no)

Other versions

NO161741B (no

NO843053L (no

Inventor

Thomas A Davidson

Robert J Murray

Original Assignee

Pennwalt Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-07-29

Filing date

1984-07-27

Publication date

1989-09-20

1984-07-27 Application filed by Pennwalt Corp filed Critical Pennwalt Corp

1985-01-30 Publication of NO843053L publication Critical patent/NO843053L/no

1989-06-12 Publication of NO161741B publication Critical patent/NO161741B/no

1989-09-20 Publication of NO161741C publication Critical patent/NO161741C/no

Links

150000005234 imidazo[1,2-a]pyridines Chemical class 0.000 title 1
150000002460 imidazoles Chemical class 0.000 title 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
SDIVEYBYOHLVIP-UHFFFAOYSA-N 8,8-dimethoxy-2-phenyl-3,5,6,7-tetrahydro-2h-imidazo[1,2-a]pyridine;hydrochloride Chemical compound Cl.N1=C2C(OC)(OC)CCCN2CC1C1=CC=CC=C1 SDIVEYBYOHLVIP-UHFFFAOYSA-N 0.000 abstract 1
239000002955 immunomodulating agent Substances 0.000 abstract 1
229940121354 immunomodulator Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Detergent Compositions (AREA)

NO843053A 1983-07-29 1984-07-27 Analogifremgangsm te ved fremstilling av pyrrolo(1,2-a)imidazoler eller imidazo(1,2-a)pyridiner. NO161741C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/518,514 US4507481A (en)	1983-07-29	1983-07-29	Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines

Publications (3)

Publication Number	Publication Date
NO843053L NO843053L (no)	1985-01-30
NO161741B NO161741B (no)	1989-06-12
NO161741C true NO161741C (no)	1989-09-20

Family

ID=24064258

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO843053A NO161741C (no)	1983-07-29	1984-07-27	Analogifremgangsm te ved fremstilling av pyrrolo(1,2-a)imidazoler eller imidazo(1,2-a)pyridiner.

Country Status (15)

Country	Link
US (1)	US4507481A (de)
EP (1)	EP0150255B1 (de)
JP (1)	JPS6042384A (de)
KR (1)	KR910002837B1 (de)
AT (1)	ATE59042T1 (de)
AU (1)	AU562722B2 (de)
CA (1)	CA1250295A (de)
DE (1)	DE3483745D1 (de)
DK (1)	DK367084A (de)
FI (1)	FI78090C (de)
IL (1)	IL71943A (de)
NO (1)	NO161741C (de)
NZ (1)	NZ208266A (de)
PH (1)	PH19437A (de)
ZA (1)	ZA844299B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4728645A (en) *	1982-12-21	1988-03-01	Ciba-Geigy Corporation	Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
US4551535A (en) *	1983-07-29	1985-11-05	Pennwalt Corporation	Process for preparing novel 7-thioester derivatives of 3H pyrrolo [1,2-a]-imidazole and 8-thioester derivatives of imidazo [1,2-a] pyridine
US4670445A (en) *	1984-03-05	1987-06-02	Eli Lilly And Company	Inotropic agents
US4719218A (en) *	1985-12-12	1988-01-12	Smithkline Beckman Corporation	Pyrrolo[1,2-a]imidazole and pyrrolo[1,2-a]pyridine derivatives and their use as 5-lipoxygenase pathway inhibitor
US5002941A (en) *	1985-12-12	1991-03-26	Smithkline Beecham Corporation	Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
US4751310A (en) *	1985-12-12	1988-06-14	Smithkline Beckman Corporation	Inhibition of the 5-lipoxygenase pathway
US5134150A (en) *	1985-12-12	1992-07-28	Smithkline Beecham Corporation	Inhibition of the 5-lipoxygenase pathway
US5145858A (en) *	1985-12-12	1992-09-08	Smithkline Beecham Corp.	Pyrrolo [1,2-a] imidazole and imidazo [1,2a] pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
US4794114A (en) *	1986-08-19	1988-12-27	Smithkline Beckman Corporation	Inhibition of interleukin-1 production by monocytes and/or macrophages
AU622330B2 (en) *	1989-06-23	1992-04-02	Takeda Chemical Industries Ltd.	Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
JPH06504779A (ja) *	1990-12-13	1994-06-02	スミスクライン・ビーチャム・コーポレイション	新規ｃｓａｉｄｓ
US5574042A (en) *	1992-11-02	1996-11-12	Fujisawa Pharmaceutical Co., Ltd	Imidazo [1,2-a] pyridines and their pharmaceutical use
AU686115B2 (en) *	1992-11-02	1998-02-05	Fujisawa Pharmaceutical Co., Ltd.	Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation
CA2134009C (en)	1993-11-11	2005-03-08	Oleg Werbitzky	Bicyclic amidines, process for their preparation, and their use as catalyst
CA2191979A1 (en) *	1994-06-20	1995-12-28	Muneo Takatani	Condensed imidazole compounds, their production and use
US10738035B2 (en)	2015-05-13	2020-08-11	Enanta Pharmaceuticals, Inc.	Hepatitis B antiviral agents
WO2017011552A1 (en)	2015-07-13	2017-01-19	Enanta Pharmaceuticals, Inc.	Hepatitis b antiviral agents
US10301255B2 (en)	2015-07-22	2019-05-28	Enanta Pharmaceuticals, Inc.	Hepatitis B antiviral agents
WO2017136403A1 (en)	2016-02-02	2017-08-10	Enanta Pharmaceuticals, Inc.	Hepatitis b antiviral agents
KR102398439B1 (ko)	2016-03-07	2022-05-16	이난타 파마슈티칼스, 인코포레이티드	B형 간염 항바이러스제
EP3468561A4 (de)	2016-06-10	2019-12-04	Enanta Pharmaceuticals, Inc.	Hepatitis-b-viruzide
SG11202001685TA (en)	2017-08-28	2020-03-30	Enanta Pharm Inc	Hepatitis b antiviral agents
WO2019113173A1 (en)	2017-12-06	2019-06-13	Enanta Pharmaceuticals, Inc.	Hepatitis b antiviral agents
US10723733B2 (en)	2017-12-06	2020-07-28	Enanta Pharmaceuticals, Inc.	Hepatitis B antiviral agents
US11058678B2 (en)	2018-01-22	2021-07-13	Enanta Pharmaceuticals, Inc.	Substituted heterocycles as antiviral agents
US10729688B2 (en)	2018-03-29	2020-08-04	Enanta Pharmaceuticals, Inc.	Hepatitis B antiviral agents
TW202024093A (zh)	2018-09-21	2020-07-01	美商安塔製藥公司	作為抗病毒劑之官能化雜環
EP3883570A4 (de)	2018-11-21	2022-07-13	Enanta Pharmaceuticals, Inc.	Funktionalisierte heterocyclen als antivirale mittel
WO2020247444A1 (en)	2019-06-03	2020-12-10	Enanta Pharmaceuticals, Inc,	Hepatitis b antiviral agents
US11472808B2 (en)	2019-06-04	2022-10-18	Enanta Pharmaceuticals, Inc.	Substituted pyrrolo[1,2-c]pyrimidines as hepatitis B antiviral agents
WO2020247561A1 (en)	2019-06-04	2020-12-10	Enanta Pharmaceuticals, Inc,	Hepatitis b antiviral agents
WO2021007488A1 (en)	2019-07-11	2021-01-14	Enanta Pharmaceuticals, Inc.	Substituted heterocycles as antiviral agents
WO2021055425A2 (en)	2019-09-17	2021-03-25	Enanta Pharmaceuticals, Inc.	Functionalized heterocycles as antiviral agents
US11802125B2 (en)	2020-03-16	2023-10-31	Enanta Pharmaceuticals, Inc.	Functionalized heterocyclic compounds as antiviral agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2984665A (en) *	1958-05-14	1961-05-16	Rohm & Haas	Condensed heterocyclic compounds
US4126685A (en) *	1975-01-31	1978-11-21	Imperial Chemical Industries Limited	6-Aryl-pyrrolo[1,2,9]imidazole derivatives which possess anti-hypertensive activity
US4096264A (en) *	1975-12-09	1978-06-20	Merck & Co., Inc.	Certain substituted imidazo [1,2-a] pyridines
EP0068378B1 (de) *	1981-06-26	1986-03-05	Schering Corporation	Imidazo(1,2-a)pyridine und -pyrazine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

1983
- 1983-07-29 US US06/518,514 patent/US4507481A/en not_active Expired - Fee Related
1984
- 1984-05-23 NZ NZ208266A patent/NZ208266A/en unknown
- 1984-05-28 IL IL71943A patent/IL71943A/xx unknown
- 1984-05-30 CA CA000455455A patent/CA1250295A/en not_active Expired
- 1984-05-30 AU AU28852/84A patent/AU562722B2/en not_active Ceased
- 1984-06-07 ZA ZA844299A patent/ZA844299B/xx unknown
- 1984-06-20 EP EP84107006A patent/EP0150255B1/de not_active Expired - Lifetime
- 1984-06-20 DE DE8484107006T patent/DE3483745D1/de not_active Expired - Fee Related
- 1984-06-20 AT AT84107006T patent/ATE59042T1/de not_active IP Right Cessation
- 1984-07-10 PH PH30953A patent/PH19437A/en unknown
- 1984-07-23 JP JP59151489A patent/JPS6042384A/ja active Pending
- 1984-07-27 DK DK367084A patent/DK367084A/da not_active Application Discontinuation
- 1984-07-27 FI FI843001A patent/FI78090C/fi not_active IP Right Cessation
- 1984-07-27 NO NO843053A patent/NO161741C/no unknown
- 1984-07-28 KR KR1019840004509A patent/KR910002837B1/ko not_active Expired

Also Published As

Publication number	Publication date
KR850001210A (ko)	1985-03-16
KR910002837B1 (ko)	1991-05-06
EP0150255A2 (de)	1985-08-07
FI78090B (fi)	1989-02-28
AU2885284A (en)	1985-01-31
CA1250295A (en)	1989-02-21
NZ208266A (en)	1987-03-31
FI843001A7 (fi)	1985-01-30
AU562722B2 (en)	1987-06-18
JPS6042384A (ja)	1985-03-06
EP0150255B1 (de)	1990-12-12
DE3483745D1 (de)	1991-01-24
IL71943A (en)	1987-07-31
DK367084A (da)	1985-01-30
IL71943A0 (en)	1984-09-30
NO161741B (no)	1989-06-12
ATE59042T1 (de)	1990-12-15
EP0150255A3 (en)	1988-01-07
NO843053L (no)	1985-01-30
PH19437A (en)	1986-04-15
FI843001A0 (fi)	1984-07-27
ZA844299B (en)	1985-01-30
DK367084D0 (da)	1984-07-27
FI78090C (fi)	1989-06-12
US4507481A (en)	1985-03-26

Publication	Publication Date	Title
AU562722B2 (en)	1987-06-18	Pyrrolo (1,2-a) imidazole and imidazo (1,2-a) pyridine immunomodulators
AU4506489A (en)	1990-05-01	Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
NO810198L (no)	1981-07-24	Fremgangsmaate ved fremstilling av imidazo (1,2-a)pyridiner.
ZA877085B (en)	1989-04-26	2-or 3-aryl substituted imidazo(1,2-a)pyridines
IE861997L (en)	1987-01-29	Zwitterionic bicyclic compounds
AU7849387A (en)	1988-03-24	2- or-3- aryl substituted imidazo(1,2-a)pyridines
NO171914C (no)	1993-05-19	Analogifremgangsmaate ved fremstilling av tricykliske pyridinderivate
NO881333D0 (no)	1988-03-25	Fremgangsmaate for fremstilling av imidazo-pyridinderivater
NO930276D0 (no)	1993-01-27	Fremgangsmaate for fremstilling av imidazo(4,5-b)pyridin-derivater
MY103766A (en)	1993-09-30	Pyrrolo[1,2-a]imidazole and imidazo[1,2-a] pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
NO801376L (no)	1980-11-12	Fremgangsmaate ved fremstilling av 3-substituerte tetrahydro-pyrrolo(1,2-a)pyrimidinderivater
NO161563C (no)	1989-08-30	Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyrazolo(1,5-a)pyridinderivater.
OA07680A (fr)	1985-05-23	Nouveaux dérivés de cyano-2 imidazo (4,5-b) pyridine. leur préparation et leur utilisation comme fongicides.
SE8400118D0 (sv)	1984-01-11	Substituted carboxy-thiazolo(3,2-a)pyrimidine derivatives and process for their preparation
AU5771780A (en)	1980-11-06	3-substituted imidazo (1,2-a) pyridines
AU548784B2 (en)	1986-01-02	Imidazo(1,2-a)imidazole derivatives
AU621308C (en)	1992-09-03	Pyrrolo(1,2-a)imidazole and pyrrolo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
GR81235B (en)	1985-04-16	Method for the preparation of pyrrolo (3,2,1-hi) indole derivatives
FI882150A7 (fi)	1988-05-06	Menetelmä pyrrolo/1,2-a/imidatsoli- ja imidatso-/1,2-a/pyridiini- immuunimodulaattorien valmistamiseksi.
ZA886511B (en)	1989-07-26	Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors