NO167090C - Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridoncarboxylsyrederivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridoncarboxylsyrederivater.

Info

Publication number: NO167090C
Authority: NO; Norway
Prior art keywords: sup; acid derivatives; preparation; sub; therapeutic active
Prior art date: 1985-06-26

Application number

NO862559A

Other languages

English (en)

Norwegian (no)

Other versions

NO167090B (no

NO862559L (no

NO862559D0 (no

Inventor

Isao Hayakawa

Shohgo Atarashi

Original Assignee

Daiichi Seiyaku Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-06-26

Filing date

1986-06-25

Publication date

1991-10-02

1986-06-25 Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co

1986-06-25 Publication of NO862559D0 publication Critical patent/NO862559D0/no

1986-12-29 Publication of NO862559L publication Critical patent/NO862559L/no

1991-06-24 Publication of NO167090B publication Critical patent/NO167090B/no

1991-10-02 Publication of NO167090C publication Critical patent/NO167090C/no

Links

239000002253 acid Substances 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004777 2-fluoroethyl group Chemical group [H]C([H])(F)C([H])([H])* 0.000 abstract 1
125000006414 CCl Chemical group ClC* 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000000845 anti-microbial effect Effects 0.000 abstract 1
125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
125000000555 isopropenyl group Chemical group [H]\C([H])=C(\*)C([H])([H])[H] 0.000 abstract 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
229920002554 vinyl polymer Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Table Devices Or Equipment (AREA)
Stringed Musical Instruments (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO862559A 1985-06-26 1986-06-25 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridoncarboxylsyrederivater. NO167090C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP13983085		1985-06-26
JP27999185		1985-12-12

Publications (4)

Publication Number	Publication Date
NO862559D0 NO862559D0 (no)	1986-06-25
NO862559L NO862559L (no)	1986-12-29
NO167090B NO167090B (no)	1991-06-24
NO167090C true NO167090C (no)	1991-10-02

Family

ID=26472527

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO862559A NO167090C (no)	1985-06-26	1986-06-25	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridoncarboxylsyrederivater.

Country Status (18)

Country	Link
US (4)	US5098912A (de)
EP (1)	EP0207420B1 (de)
JP (2)	JPH0745491B2 (de)
KR (1)	KR930005001B1 (de)
AT (1)	ATE75740T1 (de)
AU (1)	AU589978B2 (de)
CA (1)	CA1301760C (de)
DE (1)	DE3685157D1 (de)
DK (1)	DK170641B1 (de)
ES (1)	ES8707520A1 (de)
FI (1)	FI87071C (de)
GR (1)	GR861649B (de)
IE (1)	IE59188B1 (de)
IL (1)	IL79189A (de)
NO (1)	NO167090C (de)
PH (1)	PH24886A (de)
PT (1)	PT82839B (de)
YU (1)	YU46526B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3508816A1 (de) *	1985-01-10	1986-07-10	Bayer Ag, 5090 Leverkusen	6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren
US4920120A (en) *	1988-01-25	1990-04-24	Warner-Lambert Company	Antibacterial agents
US5585491A (en) *	1988-01-25	1996-12-17	Otsuka Pharmaceutical Co., Ltd.	Antibacterial agents
CA1332605C (en) *	1988-10-03	1994-10-18	Yasuhiro Nishitani	Pyridonecarboxylic acids
US5364861A (en) *	1990-11-30	1994-11-15	Warner-Lambert Company	Optical isomers of 7-[3-(1,1-dialkylmethyl-1-amino-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents
DE69131428T2 (de) *	1990-11-30	2000-01-05	Warner-Lambert Co., Ann Arbor	Individuelle stereoisomere von 7-[3-(aminoalkyl)-1-pyrrolidinyl]-quinolone und naphthyridone als antibakterielle wirkstoffe
US5157128A (en) *	1990-11-30	1992-10-20	Warner-Lambert Company	Certain optically active substituted α,α-dialkyl-pyrrolidine-3-methamines useful as intermediates
US5258528A (en) *	1990-11-30	1993-11-02	Warner-Lambert Company	Individual stereoisomers of pyrrolidine methanamines substituted on the ring nitrogen by a 1-phenylethyl group
EP0550016A1 (de) *	1991-12-31	1993-07-07	Korea Research Institute Of Chemical Technology	Chinoloncarbonsäure-Derivate und Verfahren zu ihrer Herstellung
PT807630E (pt) *	1995-02-02	2003-08-29	Daiichi Seiyaku Co	Compostos heterociclicos
JP4040091B2 (ja) *	1995-11-22	2008-01-30	第一三共株式会社	置換アミノシクロアルキルピロリジン誘導体
US6121285A (en)	1995-11-22	2000-09-19	Daiichi Pharmaceutical Co., Ltd.	Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
AU3459797A (en)	1996-07-12	1998-02-09	Daiichi Pharmaceutical Co., Ltd.	Cis-substituted aminocyclopropane derivatives
CN1263527A (zh) *	1997-05-21	2000-08-16	第一制药株式会社	顺式取代－取代氨基环烷基吡咯烷衍生物
MY119816A (en) *	1997-05-30	2005-07-29	Daiichi Seiyaku Co	Substituted cyclobutylamine derivatives
US6387928B1 (en)	1997-09-15	2002-05-14	The Procter & Gamble Co.	Antimicrobial quinolones, their compositions and uses
CN1264837C (zh) *	1997-09-15	2006-07-19	普罗克特和甘保尔公司	喹诺酮抗微生物剂、其组合物和应用
EP1082300B1 (de) *	1998-05-29	2003-09-10	PHARMACIA & UPJOHN COMPANY	3-[(1'-n-methylamino)ethyl-n-benzyl]pyrrolidin-monomethanesulfonat
CN1258531C (zh)	1999-03-10	2006-06-07	第一制药株式会社	芳香族取代基取代的氨基甲基吡咯烷衍生物
US6569686B2 (en) *	2000-01-28	2003-05-27	Pion, Inc.	Measurement of solubility-pH profiles
PT1336611E (pt) *	2000-11-20	2007-12-06	Daiichi Sankyo Co Ltd	Compostos desalogenados
PL1666477T3 (pl)	2003-09-10	2013-11-29	Kyorin Seiyaku Kk	Pochodna kwasu 7-(4-podstawionego-3-cyklopropyloaminometylo-1- pirolidynylo)chinolonokarboksylowego
WO2005030752A1 (ja) *	2003-09-29	2005-04-07	Daiichi Pharmaceutical Co., Ltd.	８−シアノキノロンカルボン酸誘導体
ES2366150T3 (es) *	2006-03-28	2011-10-17	Warner Chilcott Company, Llc	Malatos de polimorfos de ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro-8-metoxi-4-oxo-3-quinolinocarboxílico.
CA2647454A1 (en) *	2006-03-28	2007-10-04	The Procter & Gamble Company	A coupling process for preparing quinolone intermediates
BRPI0709209A2 (pt) *	2006-03-28	2011-06-28	Procter & Gamble	processo de redução de hidreto para preparo de intermediários de quinolona
JP5322927B2 (ja) *	2007-05-24	2013-10-23	杏林製薬株式会社	１４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
CN116606280A (zh) *	2023-03-13	2023-08-18	广东工业大学	一种氟喹诺酮类化合物及其在制备抗菌药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4665079A (en) *	1984-02-17	1987-05-12	Warner-Lambert Company	Antibacterial agents
IE55898B1 (en) *	1982-09-09	1991-02-14	Warner Lambert Co	Antibacterial agents
DE3318145A1 (de) *	1983-05-18	1984-11-22	Bayer Ag, 5090 Leverkusen	7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS60228479A (ja) *	1984-04-26	1985-11-13	Toyama Chem Co Ltd	１，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩
IE58742B1 (en) *	1984-07-20	1993-11-05	Warner Lambert Co	Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
DE3509546A1 (de) *	1985-03-16	1986-09-25	Bayer Ag, 5090 Leverkusen	7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4657913A (en) *	1985-04-18	1987-04-14	Warner-Lambert Company	Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
EP0242789A3 (de) *	1986-04-25	1990-09-05	Dainippon Pharmaceutical Co., Ltd.	Chinolinderivate und Verfahren zu ihrer Herstellung
US4851418A (en) *	1987-08-21	1989-07-25	Warner-Lambert Company	Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
US4920120A (en) *	1988-01-25	1990-04-24	Warner-Lambert Company	Antibacterial agents

1986
- 1986-06-23 AT AT86108547T patent/ATE75740T1/de not_active IP Right Cessation
- 1986-06-23 EP EP86108547A patent/EP0207420B1/de not_active Expired - Lifetime
- 1986-06-23 DE DE8686108547T patent/DE3685157D1/de not_active Expired - Lifetime
- 1986-06-23 IL IL79189A patent/IL79189A/xx not_active IP Right Cessation
- 1986-06-24 FI FI862688A patent/FI87071C/fi not_active IP Right Cessation
- 1986-06-25 PT PT82839A patent/PT82839B/pt unknown
- 1986-06-25 AU AU59245/86A patent/AU589978B2/en not_active Expired
- 1986-06-25 GR GR861649A patent/GR861649B/el unknown
- 1986-06-25 IE IE169686A patent/IE59188B1/en not_active IP Right Cessation
- 1986-06-25 CA CA000512446A patent/CA1301760C/en not_active Expired - Lifetime
- 1986-06-25 ES ES556754A patent/ES8707520A1/es not_active Expired
- 1986-06-25 NO NO862559A patent/NO167090C/no not_active IP Right Cessation
- 1986-06-26 YU YU112086A patent/YU46526B/sh unknown
- 1986-06-26 KR KR1019860005150A patent/KR930005001B1/ko not_active Expired - Lifetime
- 1986-06-26 DK DK304686A patent/DK170641B1/da not_active IP Right Cessation
- 1986-06-26 PH PH33956A patent/PH24886A/en unknown
- 1986-06-26 JP JP61150581A patent/JPH0745491B2/ja not_active Expired - Lifetime
1989
- 1989-12-12 US US07/449,160 patent/US5098912A/en not_active Expired - Lifetime
1991
- 1991-12-24 US US07/812,830 patent/US5416222A/en not_active Expired - Lifetime
1993
- 1993-06-21 JP JP5148887A patent/JP2686705B2/ja not_active Expired - Lifetime
1994
- 1994-03-04 US US08/205,638 patent/US5380874A/en not_active Expired - Lifetime
1995
- 1995-03-20 US US08/406,594 patent/US5476950A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
FI87071B (fi)	1992-08-14
DK304686A (da)	1987-02-23
JPH09143157A (ja)	1997-06-03
JPS62234082A (ja)	1987-10-14
KR870000321A (ko)	1987-02-17
US5380874A (en)	1995-01-10
EP0207420A3 (en)	1988-04-20
PT82839B (pt)	1988-04-21
US5416222A (en)	1995-05-16
YU46526B (sh)	1993-11-16
EP0207420B1 (de)	1992-05-06
AU589978B2 (en)	1989-10-26
FI87071C (fi)	1992-11-25
IL79189A0 (en)	1986-09-30
AU5924586A (en)	1987-01-08
ATE75740T1 (de)	1992-05-15
PT82839A (en)	1986-07-01
ES556754A0 (es)	1987-08-01
NO167090B (no)	1991-06-24
YU112086A (en)	1991-04-30
IE861696L (en)	1986-12-26
EP0207420A2 (de)	1987-01-07
DE3685157D1 (de)	1992-06-11
NO862559L (no)	1986-12-29
IE59188B1 (en)	1994-01-26
IL79189A (en)	1990-07-12
DK304686D0 (da)	1986-06-26
PH24886A (en)	1990-12-26
GR861649B (en)	1986-10-30
FI862688L (fi)	1986-12-27
JPH0745491B2 (ja)	1995-05-17
JP2686705B2 (ja)	1997-12-08
NO862559D0 (no)	1986-06-25
FI862688A0 (fi)	1986-06-24
DK170641B1 (da)	1995-11-20
KR930005001B1 (ko)	1993-06-11
CA1301760C (en)	1992-05-26
ES8707520A1 (es)	1987-08-01
US5098912A (en)	1992-03-24
US5476950A (en)	1995-12-19

Legal Events

Date	Code	Title	Description
2006-08-21	MK1K	Patent expired

Publication	Publication Date	Title
AU589978B2 (en)	1989-10-26	Pyridonecarboxylic acid derivatives
EG17753A (en)	1991-12-30	Novel pharmacological compounds
IL81002A (en)	1991-07-18	3,4-diphenyl-pyrazoline-1-carboxamide derivatives,processes for the preparation thereof and insecticidal and acaricidal compositions containing the same
NO880731D0 (no)	1988-02-19	Fremgangsmaate for fremstilling av farmasoeytisk aktive naftalenderivater.
SE8404065D0 (sv)	1984-08-10	Novel biologically active compounds
ES8701193A1 (es)	1986-11-16	Un procedimiento para preparar derivados de acido griseolico
EP0321968A3 (en)	1990-10-31	Compounds active on the cardiovascular system
AU7415387A (en)	1987-12-24	Imidazolesulfonamide derivatives and herbicides
NO163957C (no)	1990-08-15	Analogifremgangsmaate til fremstilling av terapeutisk aktive karbapenemforbindelser.
IL49835A (en)	1979-03-12	Preparation of 2,4-dioxo-1,2,3,4tetrahydro-s-triazino-(1,2-a)benzimidazoles, certain such novel compounds and fungicidal compositions containing them
ES8707553A1 (es)	1987-08-01	Procedimiento para la obtencion de un peptido.
GB2162182B (en)	1989-04-12	Pharmaceutical compounds and their preparation
WO1988003922A3 (en)	1988-06-30	Thiophenesulfonamide herbicides
IT1215238B (it)	1990-01-31	Derivati di omocisteina tiolattone,loro procedimento di preparazione e formulazioni farmaceutiche
ES8801295A1 (es)	1987-12-16	Un procedimiento para preparar derivados de fosfina
IL80990A0 (en)	1987-03-31	Substituted cyclopropyl oxime ethers,their preparation and their use as fungicides
NO863005D0 (no)	1986-07-25	Fremgangsmaate for fremstilling av terapeutisk aktive 1,4,5,6,7,8-heksahydro-2-alkyl-4-aryl-5-okso-1,7-naftyridin-3-karboksylsyreesterderivater.
ES8400443A1 (es)	1983-10-16	Mejoras introducidas en un procedimiento para la preparacion de hidroximidatos y tiolhidroximidatos heterobiciclicos y derivados ester carbamato de lso mismos.
EP0321967A3 (en)	1990-10-24	Compounds active on the cardiovascular system
JPS52131580A (en)	1977-11-04	N-substituted pyridinium-2-sulfonylimines, containing same as active ingredient
SU1262916A1 (ru)	2006-12-20	Гидразинопроизводные 1,3-диметил-5-нитрозоурацила, обладающие противомикробной активностью