NO167385C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive benzazecinderivater. - Google Patents
Analogifremgangsmaate ved fremstilling av terapeutisk aktive benzazecinderivater.Info
- Publication number
- NO167385C NO167385C NO870280A NO870280A NO167385C NO 167385 C NO167385 C NO 167385C NO 870280 A NO870280 A NO 870280A NO 870280 A NO870280 A NO 870280A NO 167385 C NO167385 C NO 167385C
- Authority
- NO
- Norway
- Prior art keywords
- chloro
- preparation
- benzazecine
- therapeutic active
- cpds
- Prior art date
Links
- LOLJNNQHTPVJJR-UHFFFAOYSA-N 1-benzazecine Chemical class N1=CC=CC=CC=CC2=CC=CC=C21 LOLJNNQHTPVJJR-UHFFFAOYSA-N 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- -1 chloro benzoyl Chemical group 0.000 abstract 3
- WZJYKHNJTSNBHV-UHFFFAOYSA-N benzo[h]quinoline Chemical compound C1=CN=C2C3=CC=CC=C3C=CC2=C1 WZJYKHNJTSNBHV-UHFFFAOYSA-N 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- NWJFECNBGMVGDV-UHFFFAOYSA-N 4-acetyl-9-chloro-2,5,6,7-tetrahydro-1h-4-benzazecine-3,8-dione Chemical compound C1CC(=O)N(C(=O)C)CCCC(=O)C2=C(Cl)C=CC=C21 NWJFECNBGMVGDV-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D227/00—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
- C07D227/02—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D227/06—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D227/08—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH26686 | 1986-01-23 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO870280D0 NO870280D0 (no) | 1987-01-22 |
| NO870280L NO870280L (no) | 1987-07-24 |
| NO167385B NO167385B (no) | 1991-07-22 |
| NO167385C true NO167385C (no) | 1991-10-30 |
Family
ID=4183090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO870280A NO167385C (no) | 1986-01-23 | 1987-01-22 | Analogifremgangsmaate ved fremstilling av terapeutisk aktive benzazecinderivater. |
Country Status (30)
| Country | Link |
|---|---|
| US (4) | US4732979A (da) |
| EP (1) | EP0230967B1 (da) |
| JP (1) | JPS62169770A (da) |
| KR (1) | KR910000659B1 (da) |
| CN (1) | CN1013111B (da) |
| AT (1) | ATE68790T1 (da) |
| AU (1) | AU590042B2 (da) |
| CS (1) | CS258147B2 (da) |
| DD (1) | DD264431A5 (da) |
| DE (1) | DE3773950D1 (da) |
| DK (1) | DK35887A (da) |
| FI (1) | FI82931C (da) |
| GB (1) | GB2185744B (da) |
| HU (1) | HU197883B (da) |
| IE (1) | IE870167L (da) |
| IL (1) | IL81317A (da) |
| IS (1) | IS3190A7 (da) |
| MC (1) | MC1795A1 (da) |
| MT (1) | MTP996B (da) |
| MW (1) | MW187A1 (da) |
| NO (1) | NO167385C (da) |
| NZ (1) | NZ218987A (da) |
| OA (1) | OA08469A (da) |
| PH (1) | PH22879A (da) |
| PL (1) | PL263796A1 (da) |
| PT (1) | PT84181B (da) |
| TN (1) | TNSN87006A1 (da) |
| YU (1) | YU7087A (da) |
| ZA (1) | ZA87407B (da) |
| ZW (1) | ZW1087A1 (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL81317A (en) * | 1986-01-23 | 1991-06-30 | Hoffmann La Roche | 1,2,4,5,6,7-hexahydro-4-benzazecine-3,8-dione derivatives,their preparation and pharmaceutical compositions containing them |
| IN167395B (da) * | 1987-07-21 | 1990-10-20 | Hoffmann La Roche | |
| US5239075A (en) * | 1991-08-21 | 1993-08-24 | Eli Lilly And Company | Process for the preparation of benzo (f) quinolinones |
| ES2169026T3 (es) * | 1991-08-21 | 2002-07-01 | Lilly Co Eli | Benzo(f)quinolinonas como inhibidores de 5-alfa-reductasa. |
| US5250539A (en) * | 1991-08-21 | 1993-10-05 | Eli Lilly And Company | Hexahydrobenzo[f]quinolinones |
| ES2125884T3 (es) * | 1991-08-21 | 1999-03-16 | Lilly Co Eli | Hexahidrobenzo(f)quinolinonas como inhibidores de la 5-alfa-reductasa. |
| WO1994022444A1 (en) * | 1993-03-29 | 1994-10-13 | Smithkline Beecham Corporation | Tricyclic compounds for inhibiting platelet aggregation |
| GB9317314D0 (en) * | 1993-08-20 | 1993-10-06 | Smithkline Beecham Corp | Compounds |
| DE69515321T2 (de) * | 1994-09-20 | 2000-08-24 | The Regents Of The University Of California, Oakland | Brefeldin a und analoge zur verbesserung synaptischer übertragungen |
| US20050067341A1 (en) * | 2003-09-25 | 2005-03-31 | Green Dennis H. | Continuous production membrane water treatment plant and method for operating same |
| US7094331B2 (en) * | 2003-11-05 | 2006-08-22 | Marathon Ashland Petroleum Llc | Viscosity modification of heavy hydrocarbons using dihydric alcohols |
| US20090263439A1 (en) * | 2008-04-18 | 2009-10-22 | The Procter & Gamble Company | Antimicrobial Preservative Free Wipe |
| CN106117028B (zh) * | 2016-06-14 | 2019-01-01 | 浙江永太药业有限公司 | 一种制备卤代-3,4-二氢-1h-2-萘酮的工艺方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE442586A (da) * | 1940-07-31 | |||
| JPS5129710B2 (da) * | 1972-09-09 | 1976-08-27 | ||
| US4341786A (en) * | 1981-03-02 | 1982-07-27 | Smithkline Corporation | Pharmaceutical compositions and method of producing central alpha1 agonist activity utilizing octahydrobenzo[f]quinoline compounds |
| US4521423A (en) * | 1983-10-31 | 1985-06-04 | Ayerst, Mckenna & Harrison, Ltd. | 7,8,9,10-Tetrahydrobenzo[h]quinolin-9-amine derivatives and compositions and methods for treating depression employing them |
| IL81317A (en) * | 1986-01-23 | 1991-06-30 | Hoffmann La Roche | 1,2,4,5,6,7-hexahydro-4-benzazecine-3,8-dione derivatives,their preparation and pharmaceutical compositions containing them |
-
1987
- 1987-01-20 IL IL81317A patent/IL81317A/xx unknown
- 1987-01-20 AT AT87100733T patent/ATE68790T1/de not_active IP Right Cessation
- 1987-01-20 CS CS87418A patent/CS258147B2/cs unknown
- 1987-01-20 DE DE8787100733T patent/DE3773950D1/de not_active Expired - Lifetime
- 1987-01-20 FI FI870220A patent/FI82931C/fi not_active IP Right Cessation
- 1987-01-20 PH PH34744A patent/PH22879A/en unknown
- 1987-01-20 EP EP87100733A patent/EP0230967B1/de not_active Expired - Lifetime
- 1987-01-20 ZA ZA87407A patent/ZA87407B/xx unknown
- 1987-01-20 YU YU00070/87A patent/YU7087A/xx unknown
- 1987-01-20 MW MW1/87A patent/MW187A1/xx unknown
- 1987-01-20 NZ NZ218987A patent/NZ218987A/en unknown
- 1987-01-21 ZW ZW10/87A patent/ZW1087A1/xx unknown
- 1987-01-21 DD DD87299380A patent/DD264431A5/de unknown
- 1987-01-21 US US07/005,712 patent/US4732979A/en not_active Expired - Fee Related
- 1987-01-21 HU HU87163A patent/HU197883B/hu not_active IP Right Cessation
- 1987-01-22 IE IE870167A patent/IE870167L/xx unknown
- 1987-01-22 AU AU67911/87A patent/AU590042B2/en not_active Ceased
- 1987-01-22 PT PT84181A patent/PT84181B/pt not_active IP Right Cessation
- 1987-01-22 DK DK035887A patent/DK35887A/da not_active Application Discontinuation
- 1987-01-22 IS IS3190A patent/IS3190A7/is unknown
- 1987-01-22 CN CN87100312A patent/CN1013111B/zh not_active Expired
- 1987-01-22 TN TNTNSN87006A patent/TNSN87006A1/fr unknown
- 1987-01-22 MC MC871868A patent/MC1795A1/fr unknown
- 1987-01-22 MT MT996A patent/MTP996B/xx unknown
- 1987-01-22 NO NO870280A patent/NO167385C/no unknown
- 1987-01-22 JP JP62011477A patent/JPS62169770A/ja active Pending
- 1987-01-22 GB GB8701416A patent/GB2185744B/en not_active Expired
- 1987-01-23 KR KR1019870000533A patent/KR910000659B1/ko not_active Expired
- 1987-01-23 PL PL1987263796A patent/PL263796A1/xx unknown
- 1987-01-23 OA OA59052A patent/OA08469A/xx unknown
- 1987-11-18 US US07/121,987 patent/US4749791A/en not_active Expired - Fee Related
-
1988
- 1988-02-11 US US07/154,760 patent/US4876340A/en not_active Expired - Fee Related
-
1989
- 1989-08-17 US US07/395,380 patent/US4957911A/en not_active Expired - Fee Related
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