LU88790I2 - Moxidectin et ses dérivés pharmaceutiquement acceptables - Google Patents

Moxidectin et ses dérivés pharmaceutiquement acceptables

Info

Publication number: LU88790I2
Authority: LU; Luxembourg
Prior art keywords: moxidectin; pharmaceutically acceptable; acceptable derivatives; derivatives; pharmaceutically
Prior art date: 1986-06-06

Application number

LU88790C

Other languages

English (en)

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-06-06

Filing date

1996-07-17

Publication date

1997-03-18

1986-06-06 Priority claimed from GB868613790A external-priority patent/GB8613790D0/en

1986-10-29 Priority claimed from GB868625854A external-priority patent/GB8625854D0/en

1987-04-08 Priority claimed from GB878708423A external-priority patent/GB8708423D0/en

1996-07-17 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1997-03-18 Publication of LU88790I2 publication Critical patent/LU88790I2/fr

Links

YZBLFMPOMVTDJY-CBYMMZEQSA-N moxidectin Chemical compound O1[C@H](C(\C)=C\C(C)C)[C@@H](C)C(=N/OC)\C[C@@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 YZBLFMPOMVTDJY-CBYMMZEQSA-N 0.000 title 1
229960004816 moxidectin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Plant Pathology (AREA)
Pest Control & Pesticides (AREA)
Dentistry (AREA)
Agronomy & Crop Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Insects & Arthropods (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

LU88790C 1986-06-06 1996-07-17 Moxidectin et ses dérivés pharmaceutiquement acceptables LU88790I2 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB868613790A GB8613790D0 (en)	1986-06-06	1986-06-06	Chemical compounds
GB868625854A GB8625854D0 (en)	1986-10-29	1986-10-29	Chemical process
GB878708423A GB8708423D0 (en)	1987-04-08	1987-04-08	Chemical compounds

Publications (1)

Publication Number	Publication Date
LU88790I2 true LU88790I2 (fr)	1997-03-18

Family

ID=27263057

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
LU86908A LU86908A1 (fr)	1986-06-06	1987-06-05	Composes antibiotiques,leur preparation et les compositions pharmaceutiques qui les contiennent
LU88790C LU88790I2 (fr)	1986-06-06	1996-07-17	Moxidectin et ses dérivés pharmaceutiquement acceptables

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
LU86908A LU86908A1 (fr)	1986-06-06	1987-06-05	Composes antibiotiques,leur preparation et les compositions pharmaceutiques qui les contiennent

Country Status (35)

Country	Link
US (1)	US4900753A (fr)
JP (1)	JP2648147B2 (fr)
KR (1)	KR950010077B1 (fr)
CN (1)	CN1023858C (fr)
AR (1)	AR244691A1 (fr)
AT (1)	AT398571B (fr)
AU (1)	AU609399B2 (fr)
BE (1)	BE1000201A4 (fr)
BR (1)	BR8702866A (fr)
CA (1)	CA1296329C (fr)
CH (1)	CH677670A5 (fr)
DE (3)	DE3718926C2 (fr)
DK (1)	DK166498B1 (fr)
EG (1)	EG18752A (fr)
ES (1)	ES2006479A6 (fr)
FI (2)	FI90663C (fr)
FR (1)	FR2599742B1 (fr)
GB (1)	GB2192630B (fr)
GE (1)	GEP19981388B (fr)
GR (1)	GR870891B (fr)
HU (1)	HU199847B (fr)
IE (1)	IE60411B1 (fr)
IL (1)	IL82776A (fr)
IT (1)	IT1206015B (fr)
LU (2)	LU86908A1 (fr)
LV (2)	LV10280A (fr)
NL (2)	NL193376C (fr)
NZ (1)	NZ220587A (fr)
OA (1)	OA08606A (fr)
PH (1)	PH23948A (fr)
PL (3)	PL153036B1 (fr)
PT (1)	PT85018B (fr)
SE (1)	SE503399C2 (fr)
TR (1)	TR28970A (fr)
UA (1)	UA45300C2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0260537A1 (fr) *	1986-09-12	1988-03-23	American Cyanamid Company	Dérivés 13-déoxy-23-oxo(céto) et 23-imino des composés de 13-déoxy-C-076-aglycone
ATE109783T1 (de) *	1986-09-12	1994-08-15	American Cyanamid Co	23-oxo(keto) und 23-imino-derivate von ll-f28249- verbindungen.
US4886828A (en) *	1986-09-12	1989-12-12	American Cyanamid Company	Δ22 -derivatives of LL-F28249 compounds
GB8721377D0 (en) *	1987-09-11	1987-10-21	Glaxo Group Ltd	Chemical compounds
GB8811036D0 (en) *	1988-05-10	1988-06-15	Glaxo Group Ltd	Chemical compounds
GB8813150D0 (en) *	1988-06-03	1988-07-06	American Cyanamid Co	Chemical compounds
GB8905605D0 (en) *	1989-03-11	1989-04-26	Beecham Group Plc	Novel compounds
NZ233680A (en) *	1989-05-17	1995-02-24	Beecham Group Plc	Avermectins and milbemycins and compositions thereof
US4988824A (en) *	1989-09-11	1991-01-29	Maulding Donald R	Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds
EP0561990B1 (fr) *	1990-12-07	1998-10-07	Temple University	Compositions insecticides stabilisees contenant des nematodes
JP2855181B2 (ja)	1993-12-10	1999-02-10	敏雄鈴木	松類の枯損防止用組成物及び防止方法
PT1197215E (pt)	2000-10-10	2006-07-31	Wyeth Corp	Composicoes antelminticas
US7348417B2 (en) *	2003-08-07	2008-03-25	Wyeth	Method of purifying moxidectin through crystallization
WO2006119174A1 (fr)	2005-04-30	2006-11-09	Ocular Surface Center, P.A.	Methode de traitement oculaire de demodex
JP4939025B2 (ja) *	2005-09-30	2012-05-23	三菱電線工業株式会社	電熱ヒータ付きハンドル用グリップ部材
EP1849363A1 (fr) *	2006-03-09	2007-10-31	Cheminova A/S	Combinations synergiques d'un plaguicide agoniste des canaux à chlorure actives par le glutamate ou le GABA et au moins un d'entre la vitamine E et la niacin
US8128968B2 (en) *	2007-08-29	2012-03-06	Tissuetech, Inc.	Compositions and methods for treating Demodex infestations
WO2013082373A1 (fr)	2011-12-02	2013-06-06	Merial Limited	Formulations de moxidectine injectable à action prolongée et nouveau cristal de moxidectine
FR2995605B1 (fr) *	2012-09-18	2014-09-19	Sanofi Sa	Derives de macrolides, leur preparation et leur application therapeutique.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH15982A (en) *	1977-10-03	1983-05-18	Merck & Co Inc	Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4289760A (en) *	1980-05-02	1981-09-15	Merck & Co., Inc.	23-Keto derivatives of C-076 compounds
US4423209A (en) *	1982-02-26	1983-12-27	Merck & Co., Inc.	Processes for the interconversion of avermectin compounds
JPS59108785A (ja) *	1982-11-25	1984-06-23	Sankyo Co Ltd	ミルベマイシン類の５−オキシム誘導体
JPS60126289A (ja) *	1983-11-14	1985-07-05	Sankyo Co Ltd	ミルベマイシン類の５−カ−ボネ−ト誘導体
DE3519834C2 (de) *	1984-06-05	1993-12-16	American Cyanamid Co	Neue antibiotische Wirkstoffe, Verfahren zu ihrer Gewinnung und ihre Anwendung zur Bekämpfung von Infektionen bei Tieren und Pflanzen
US4579864A (en) *	1984-06-11	1986-04-01	Merck & Co., Inc.	Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
CH666690A5 (de) *	1984-09-14	1988-08-15	Glaxo Group Ltd	Antibiotisch wirkende verbindungen der makrolidgruppe aus streptomyces-mikroorganismen, ihre herstellung und verwendung.
IL78621A (en) *	1985-04-30	1991-06-30	American Cyanamid Co	Mylbemycin analogs,their preparation and pesticidal compositions containing them
ATE109783T1 (de) *	1986-09-12	1994-08-15	American Cyanamid Co	23-oxo(keto) und 23-imino-derivate von ll-f28249- verbindungen.

1987
- 1987-05-26 CA CA000537979A patent/CA1296329C/fr not_active Expired - Lifetime
- 1987-06-02 OA OA59131A patent/OA08606A/xx unknown
- 1987-06-04 DK DK290287A patent/DK166498B1/da not_active IP Right Cessation
- 1987-06-04 ES ES8701645A patent/ES2006479A6/es not_active Expired
- 1987-06-04 FI FI872517A patent/FI90663C/fi not_active IP Right Cessation
- 1987-06-04 EG EG32487A patent/EG18752A/xx active
- 1987-06-05 BE BE8700626A patent/BE1000201A4/fr not_active IP Right Cessation
- 1987-06-05 BR BR8702866A patent/BR8702866A/pt not_active IP Right Cessation
- 1987-06-05 KR KR1019870005694A patent/KR950010077B1/ko not_active Expired - Lifetime
- 1987-06-05 PL PL1987283187A patent/PL153036B1/pl unknown
- 1987-06-05 PH PH35347A patent/PH23948A/en unknown
- 1987-06-05 PT PT85018A patent/PT85018B/pt unknown
- 1987-06-05 JP JP62140139A patent/JP2648147B2/ja not_active Expired - Lifetime
- 1987-06-05 TR TR00392/87A patent/TR28970A/xx unknown
- 1987-06-05 AU AU73873/87A patent/AU609399B2/en not_active Expired
- 1987-06-05 DE DE3718926A patent/DE3718926C2/de not_active Expired - Lifetime
- 1987-06-05 DE DE1998175029 patent/DE19875029I2/de active Active
- 1987-06-05 IT IT8748023A patent/IT1206015B/it active
- 1987-06-05 GR GR870891A patent/GR870891B/el unknown
- 1987-06-05 GB GB8713239A patent/GB2192630B/en not_active Expired - Lifetime
- 1987-06-05 PL PL1987282198A patent/PL155723B1/pl unknown
- 1987-06-05 CH CH2150/87A patent/CH677670A5/de not_active IP Right Cessation
- 1987-06-05 AT AT0143887A patent/AT398571B/de not_active IP Right Cessation
- 1987-06-05 FR FR878707915A patent/FR2599742B1/fr not_active Expired
- 1987-06-05 US US07/058,856 patent/US4900753A/en not_active Expired - Lifetime
- 1987-06-05 IL IL82776A patent/IL82776A/xx not_active IP Right Cessation
- 1987-06-05 DE DE3745133A patent/DE3745133C2/de not_active Expired - Lifetime
- 1987-06-05 IE IE149687A patent/IE60411B1/en not_active IP Right Cessation
- 1987-06-05 HU HU872583A patent/HU199847B/hu unknown
- 1987-06-05 SE SE8702361A patent/SE503399C2/sv not_active IP Right Cessation
- 1987-06-05 PL PL1987266100A patent/PL153226B1/pl unknown
- 1987-06-05 AR AR87307796A patent/AR244691A1/es active
- 1987-06-05 NZ NZ220587A patent/NZ220587A/xx unknown
- 1987-06-05 CN CN87104431A patent/CN1023858C/zh not_active Expired - Lifetime
- 1987-06-05 LU LU86908A patent/LU86908A1/fr active Protection Beyond IP Right Term
- 1987-06-05 NL NL8701322A patent/NL193376C/nl not_active IP Right Cessation
1992
- 1992-07-30 FI FI923445A patent/FI90549C/fi not_active IP Right Cessation
- 1992-12-30 LV LV920561A patent/LV10280A/xx unknown
1993
- 1993-08-25 GE GEAP19931498A patent/GEP19981388B/en unknown
- 1993-09-15 UA UA93003885A patent/UA45300C2/uk unknown
- 1993-11-15 LV LVP-93-1233A patent/LV10781B/lv unknown
1996
- 1996-07-17 LU LU88790C patent/LU88790I2/fr unknown
1999
- 1999-08-18 NL NL990026C patent/NL990026I2/nl unknown

Also Published As

Publication number	Publication date
FR2599742B1 (fr)	1989-05-19
FI923445A0 (fi)	1992-07-30
PL266100A1 (en)	1988-07-21
DE3745133C2 (de)	1998-01-02
SE8702361D0 (sv)	1987-06-05
NZ220587A (en)	1990-05-28
LV10280A (lv)	1994-10-20
NL990026I2 (nl)	1999-12-01
TR28970A (tr)	1997-07-21
DE3718926C2 (de)	1998-01-15
KR950010077B1 (ko)	1995-09-06
GB2192630B (en)	1990-05-23
PT85018A (en)	1987-07-01
HUT44254A (en)	1988-02-29
PL153226B1 (en)	1991-03-29
DK290287A (da)	1987-12-07
SE503399C2 (sv)	1996-06-10
CH677670A5 (fr)	1991-06-14
GEP19981388B (en)	1998-11-10
DK166498B1 (da)	1993-06-01
IL82776A (en)	1992-02-16
FI90663C (fi)	1994-03-10
GB2192630A (en)	1988-01-20
FR2599742A1 (fr)	1987-12-11
US4900753A (en)	1990-02-13
CA1296329C (fr)	1992-02-25
EG18752A (en)	1993-12-30
NL193376C (nl)	1999-08-03
JPS6354375A (ja)	1988-03-08
PL153036B1 (en)	1991-02-28
CN1023858C (zh)	1994-02-23
FI923445L (fi)	1992-07-30
BE1000201A4 (fr)	1988-08-23
PL155723B1 (en)	1991-12-31
LU86908A1 (fr)	1988-01-20
GB8713239D0 (en)	1987-07-08
FI90663B (fi)	1993-11-30
DE19875029I2 (de)	2001-11-22
AR244691A1 (es)	1993-11-30
ES2006479A6 (es)	1989-05-01
NL990026I1 (nl)	1999-11-01
BR8702866A (pt)	1988-03-01
FI90549C (fi)	1994-02-25
KR880000441A (ko)	1988-03-25
ATA143887A (de)	1994-05-15
FI90549B (fi)	1993-11-15
IE871496L (en)	1987-12-06
PH23948A (en)	1990-01-23
SE8702361L (sv)	1987-12-07
AT398571B (de)	1994-12-27
HU199847B (en)	1990-03-28
NL8701322A (nl)	1988-01-04
UA45300C2 (uk)	2002-04-15
LV10781B (en)	1996-10-20
PT85018B (pt)	1990-03-08
FI872517A7 (fi)	1987-12-07
IE60411B1 (en)	1994-07-13
OA08606A (en)	1988-11-30
IT8748023A0 (it)	1987-06-05
FI872517A0 (fi)	1987-06-04
DE3718926A1 (de)	1987-12-10
IT1206015B (it)	1989-04-05
GR870891B (en)	1987-10-02
NL193376B (nl)	1999-04-01
JP2648147B2 (ja)	1997-08-27
IL82776A0 (en)	1987-12-20
AU7387387A (en)	1987-12-10
LV10781A (lv)	1995-08-20
CN87104431A (zh)	1987-12-30
AU609399B2 (en)	1991-05-02
DK290287D0 (da)	1987-06-04

Publication	Publication Date	Title
LU90829I2 (fr)	2001-11-12	Tepoxalin-zubrin et ses d-riv-s pharmaceutiquement acceptables
LU91039I2 (fr)	2003-11-05	Proteq flu et ses dérivés pharmaceutiquement acceptables
LU90219I2 (fr)	1998-05-28	Tolcapone et ses dérivés pharmaceutiquement acceptables (TASMAR)
LU91205I2 (fr)	2006-05-30	Ciclesonide et ses dérivés pharmaceutiquement acceptables (alvesco)
LU88736I2 (fr)	1996-08-23	Cefquinome et ses dérivés pharmaceutiquement acceptables (COBACTAN)
LU90769I2 (fr)	2001-07-02	Capecitabine et ses d-riv-es pharmaceutiquement acceptables (xeloda)
LU90069I2 (fr)	1997-07-23	Lercanidipine et ses sels et dérivés pharmaceutiquement acceptables (Zanidip)
LU88750I2 (fr)	1996-08-23	VENLAFAXINE et ses dérivés pharmaceutiquement acceptables
LU88790I2 (fr)	1997-03-18	Moxidectin et ses dérivés pharmaceutiquement acceptables
LU90736I2 (fr)	2001-05-07	Agenerase-amprenavir et ses d-riv-s pharmaceutiquement acceptables
NL194821B (nl)	2002-12-02	Farmacologisch actieve catecholderivaten en samenstellingen ervan.
LU90037I2 (fr)	1997-06-13	Konakion et ses dérivés pharmaceutiquement acceptables
LU91197I2 (fr)	2005-10-31	Azoxystrobin et folpel et leurs dérivés pharmaceutiquement acceptables (QUADRIS MAX).
DK152287D0 (da)	1987-03-25	Farmaceutisk vaginalmiddel
FI873465A0 (fi)	1987-08-10	Kompositioner foer parenteral administrering och anvaendning av dessa.
LU88843I2 (fr)	1997-03-14	Ropivacaine et ses dérivés pharmaceutiquement acceptables (Naropine R)
TR24895A (tr)	1992-07-01	PIRIMIDIN TüREVLERI,BUNLARIN ISTIHSAL EDILMESI VE KULLANILMASI
DK254488D0 (da)	1988-05-09	Azaindol- og indolizinderivater
DK641587D0 (da)	1987-12-07	Benzofuran- og benzopyranderivater
LU90110I2 (fr)	1997-09-25	Penciclovir et ses dérivés pharmaceutiquement acceptables
LU88789I2 (fr)	1996-11-05	Mésylate de tirilazad et ses dérivés pharmaceutiquement acceptables (Freedox (R))
NO892470D0 (no)	1989-06-14	Fremstilling av laktolderivater.
FI904673A0 (fi)	1990-09-21	2,6-dioksopiperidiinijohdannaisten valmistus
DK46288A (da)	1988-08-01	Pilocarpinderivater
DE3787471D1 (de)	1993-10-21	4"-Desoxy-3"-demethoxy-3"-methylen-desmycosin-Derivate.