NO169388C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-amino-1,2-ditiol-3-onderivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-amino-1,2-ditiol-3-onderivater

Info

Publication number: NO169388C
Authority: NO; Norway
Prior art keywords: amino; substituted; alkyl; dialkylcarbamoyl; alkylcarbamoyl
Prior art date: 1983-02-24

Application number

NO840698A

Other languages

English (en)

Norwegian (no)

Other versions

NO169388B (no

NO840698L (no

Inventor

Jean-Dominique Bourzat

Claude Cotrel

Daniel Farge

Jean-Marc Paris

Gerard Taurand

Original Assignee

Rhone Poulenc Sante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-02-24

Filing date

1984-02-23

Publication date

1992-06-17

1984-02-23 Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante

1984-08-27 Publication of NO840698L publication Critical patent/NO840698L/no

1992-03-09 Publication of NO169388B publication Critical patent/NO169388B/no

1992-06-17 Publication of NO169388C publication Critical patent/NO169388C/no

Links

230000001225 therapeutic effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 5
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
125000005115 alkyl carbamoyl group Chemical group 0.000 abstract 3
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 3
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
125000005117 dialkylcarbamoyl group Chemical group 0.000 abstract 3
UWYZHKAOTLEWKK-UHFFFAOYSA-N 1,2,3,4-tetrahydroisoquinoline Chemical compound C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 abstract 2
LBUJPTNKIBCYBY-UHFFFAOYSA-N 1,2,3,4-tetrahydroquinoline Chemical compound C1=CC=C2CCCNC2=C1 LBUJPTNKIBCYBY-UHFFFAOYSA-N 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000003282 alkyl amino group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
125000004093 cyano group Chemical group *C#N 0.000 abstract 2
125000004663 dialkyl amino group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
HORKYAIEVBUXGM-UHFFFAOYSA-N 1,2,3,4-tetrahydroquinoxaline Chemical compound C1=CC=C2NCCNC2=C1 HORKYAIEVBUXGM-UHFFFAOYSA-N 0.000 abstract 1
MZBVNYACSSGXID-UHFFFAOYSA-N 2,3,4,5-tetrahydro-1h-1-benzazepine Chemical compound N1CCCCC2=CC=CC=C21 MZBVNYACSSGXID-UHFFFAOYSA-N 0.000 abstract 1
BGDOLELXXPTPFX-UHFFFAOYSA-N 3,4-dihydro-2h-1,2-benzoxazine Chemical compound C1=CC=C2ONCCC2=C1 BGDOLELXXPTPFX-UHFFFAOYSA-N 0.000 abstract 1
229940123907 Disease modifying antirheumatic drug Drugs 0.000 abstract 1
230000003356 anti-rheumatic effect Effects 0.000 abstract 1
239000003435 antirheumatic agent Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
-1 hydroxy, amino Chemical group 0.000 abstract 1
GWVMLCQWXVFZCN-UHFFFAOYSA-N isoindoline Chemical group C1=CC=C2CNCC2=C1 GWVMLCQWXVFZCN-UHFFFAOYSA-N 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

NO840698A 1983-02-24 1984-02-23 Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-amino-1,2-ditiol-3-onderivater NO169388C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8303005A FR2541680B1 (fr)	1983-02-24	1983-02-24	Nouveaux derives de l'amino-5 dithiole-1,2 one-3, leur preparation et les compositions medicinales qui les contiennent

Publications (3)

Publication Number	Publication Date
NO840698L NO840698L (no)	1984-08-27
NO169388B NO169388B (no)	1992-03-09
NO169388C true NO169388C (no)	1992-06-17

Family

ID=9286218

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO840698A NO169388C (no)	1983-02-24	1984-02-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-amino-1,2-ditiol-3-onderivater

Country Status (18)

Country	Link
US (1)	US4576954A (da)
EP (1)	EP0119896B1 (da)
JP (1)	JPS59163383A (da)
KR (1)	KR900006745B1 (da)
AT (1)	ATE22690T1 (da)
AU (1)	AU567718B2 (da)
CA (1)	CA1227197A (da)
DE (1)	DE3460896D1 (da)
DK (1)	DK159111C (da)
ES (1)	ES529986A0 (da)
FR (1)	FR2541680B1 (da)
GR (1)	GR81662B (da)
HU (1)	HU194863B (da)
IE (1)	IE56920B1 (da)
NO (1)	NO169388C (da)
NZ (1)	NZ207244A (da)
SU (1)	SU1318164A3 (da)
ZA (1)	ZA841274B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU728488B2 (en) *	1997-04-02	2001-01-11	Sankyo Company Limited	Dithiolan derivatives, their preparation and their therapeutic effect
BRPI0618643A2 (pt)	2005-11-09	2011-09-06	Combinatorx Inc	composição compreendendo um par de fármacos, composição compreendendo um corticosteróide e um imunossupressor dependente de imunofilina não-esteróide, kits e uso
WO2015074081A1 (en)	2013-11-18	2015-05-21	Bair Kenneth W	Benzopiperazine compositions as bet bromodomain inhibitors
KR102007796B1 (ko)	2013-11-18	2019-08-07	포르마 세라퓨틱스 인크.	Bet 브로모도메인 저해제로서 테트라하이드로퀴놀린 조성물
TW202009235A (zh)	2018-08-17	2020-03-01	印度商皮埃企業有限公司	1,2-二硫醇酮化合物及其用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3527867A (en) *	1965-06-11	1970-09-08	Geigy Chem Corp	Agents inhibiting fungus growth and method of controlling fungi therewith
FR1498374A (fr) *	1965-06-11	1967-10-20	Agripat Sa	Produits fongicides et bactéricides, utilisables en agriculture
US3772273A (en) *	1969-01-17	1973-11-13	Allied Chem	Derivatives of quinoxaline
US3984405A (en) *	1971-06-28	1976-10-05	E. R. Squibb & Sons, Inc.	Anti-inflammatory agents
BE795970A (fr) *	1972-02-29	1973-08-27	Pfizer	Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant
JPS5819644B2 (ja) *	1975-03-13	1983-04-19	ウェルファイド株式会社	スイチユウボウオザイ
FR2347928A1 (fr) *	1976-04-15	1977-11-10	Rhone Poulenc Ind	Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent
SE444319B (sv) *	1977-11-18	1986-04-07	Roussel Uclaf	Nya imidazobensoxazinderivat, forfarande for framstellning derav och farmaceutiska kompositioner innehallande dessa foreningar
US4254118A (en) *	1979-08-13	1981-03-03	Ayerst, Mckenna & Harrison Inc.	1-Oxo-5H-pyrimido[2,1-c][1,4]benzthiazine-2-carboxylic acid esters
US4273773A (en) *	1979-09-24	1981-06-16	American Home Products Corporation	Antihypertensive tricyclic isoindole derivatives
US4477378A (en) *	1980-02-05	1984-10-16	Schering Corp.	Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
CA1211437A (en) *	1981-08-12	1986-09-16	Rene Borer	Benzazepines

1983
- 1983-02-24 FR FR8303005A patent/FR2541680B1/fr not_active Expired
1984
- 1984-02-21 ZA ZA841274A patent/ZA841274B/xx unknown
- 1984-02-21 US US06/582,043 patent/US4576954A/en not_active Expired - Fee Related
- 1984-02-22 GR GR73885A patent/GR81662B/el unknown
- 1984-02-22 NZ NZ207244A patent/NZ207244A/en unknown
- 1984-02-22 IE IE418/84A patent/IE56920B1/en not_active IP Right Cessation
- 1984-02-23 HU HU84724A patent/HU194863B/hu not_active IP Right Cessation
- 1984-02-23 NO NO840698A patent/NO169388C/no unknown
- 1984-02-23 CA CA000448088A patent/CA1227197A/fr not_active Expired
- 1984-02-23 AU AU24855/84A patent/AU567718B2/en not_active Ceased
- 1984-02-23 AT AT84400368T patent/ATE22690T1/de active
- 1984-02-23 DK DK093984A patent/DK159111C/da not_active IP Right Cessation
- 1984-02-23 ES ES529986A patent/ES529986A0/es active Granted
- 1984-02-23 JP JP59031542A patent/JPS59163383A/ja active Pending
- 1984-02-23 SU SU843703553A patent/SU1318164A3/ru active
- 1984-02-23 KR KR1019840000890A patent/KR900006745B1/ko not_active Expired
- 1984-02-23 EP EP84400368A patent/EP0119896B1/fr not_active Expired
- 1984-02-23 DE DE8484400368T patent/DE3460896D1/de not_active Expired

Also Published As

Publication number	Publication date
EP0119896B1 (fr)	1986-10-08
IE840418L (en)	1984-08-24
JPS59163383A (ja)	1984-09-14
DE3460896D1 (en)	1986-11-13
HUT35663A (en)	1985-07-29
GR81662B (da)	1984-12-12
AU2485584A (en)	1984-08-30
NO169388B (no)	1992-03-09
FR2541680B1 (fr)	1985-06-14
ATE22690T1 (de)	1986-10-15
DK159111C (da)	1991-02-11
NZ207244A (en)	1986-12-05
DK93984A (da)	1984-08-25
FR2541680A1 (fr)	1984-08-31
ES8500939A1 (es)	1984-11-01
ES529986A0 (es)	1984-11-01
IE56920B1 (en)	1992-01-29
DK159111B (da)	1990-09-03
KR840008025A (ko)	1984-12-12
DK93984D0 (da)	1984-02-23
EP0119896A1 (fr)	1984-09-26
CA1227197A (fr)	1987-09-22
HU194863B (en)	1988-03-28
SU1318164A3 (ru)	1987-06-15
US4576954A (en)	1986-03-18
NO840698L (no)	1984-08-27
AU567718B2 (en)	1987-12-03
ZA841274B (en)	1984-09-26
KR900006745B1 (ko)	1990-09-20

Publication	Publication Date	Title
MX9504349A (es)	1997-03-29	Derivados de aroilpiperidina.
DK245888A (da)	1988-05-05	4-aminoquinolinderivater
DE69835430D1 (de)	2006-09-14	Sulfonamidderivate, ihre herstellung und verwendung
AU556150B2 (en)	1986-10-23	Dihydropyridine derivatives
EA199700098A1 (ru)	1997-12-30	Производные индола, пригодные для лечения остеопороза
RU97117350A (ru)	1999-07-20	Ингибитор гипертрофии интимы, применение оксиндолового производного для получения ингибитора гипертрофии интимы, композиция для ингибирования гипертрофии интимы, способ предупреждения и лечения гипертрофии интимы
TR199900138T2 (xx)	1999-04-21	Osteoporozun tedavisi i�in indolin t�revleri.
ES8500247A1 (es)	1984-10-01	Un procedimiento para la preparacion de un isomero optico en su forma (-) de un derivado de triazina.
ES2010284A6 (es)	1989-11-01	Procedimiento para preparar derivados de tiourea.
NO169388C (no)	1992-06-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-amino-1,2-ditiol-3-onderivater
DK13484A (da)	1984-07-13	Forbindelser med antihypertensiv virkning
HUP9901247A2 (hu)	1999-08-30	Naftimidazol-, naftoxazol- és naftotiazol-dion-származékok alkalmazása érrendszeri elváltozások okozta betegségek kezelésére szolgáló gyógyszerkészítmények előállítására, valamint új származékok
SE8105689L (sv)	1982-03-27	Terapeutiska medel
RU95104934A (ru)	1997-04-10	Производные альфа-(третичного аминометил)бензолметанола, способ их получения, их применение, способ лечения, фармкомпозиция
NO932382D0 (no)	1993-06-29	Heterocykliske forbindelser
NO870251L (no)	1987-07-23	Fremgangsmaate for fremstilling av terapeutisk aktive imidazopyridiner.
DK159650C (da)	1991-04-08	1,1-diphenylpropan-1-ol-derivater, fremgangsmaade til fremstilling heraf, farmaceutiske praeparater indeholdende disse, samt fremgangsmaade til fremstilling af disse farmaceutiske praeparater
JPS5495734A (en)	1979-07-28	Antiphlogistic analgesic agent