NO171274C - Tetrahydrocannabinolderivater samt anvendelse derav ved immunoassay for paavisning av cannabinol-metabolitter - Google Patents

Tetrahydrocannabinolderivater samt anvendelse derav ved immunoassay for paavisning av cannabinol-metabolitter

Info

Publication number: NO171274C
Authority: NO; Norway
Prior art keywords: derivative; cannabinol; group; immunoassay; derivatives
Prior art date: 1987-01-27

Application number

NO880330A

Other languages

English (en)

Norwegian (no)

Other versions

NO880330D0 (no

NO880330L (no

NO171274B (no

Inventor

Alan Joseph Mcnally

Alan Schwartz

Magdalena Usategui

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-01-27

Filing date

1988-01-26

Publication date

1993-02-17

1988-01-26 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1988-01-26 Publication of NO880330D0 publication Critical patent/NO880330D0/no

1988-07-28 Publication of NO880330L publication Critical patent/NO880330L/no

1992-11-09 Publication of NO171274B publication Critical patent/NO171274B/no

1993-02-17 Publication of NO171274C publication Critical patent/NO171274C/no

Links

VBGLYOIFKLUMQG-UHFFFAOYSA-N Cannabinol Chemical class C1=C(C)C=C2C3=C(O)C=C(CCCCC)C=C3OC(C)(C)C2=C1 VBGLYOIFKLUMQG-UHFFFAOYSA-N 0.000 title abstract 4
238000003018 immunoassay Methods 0.000 title abstract 2
CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical class C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 title 1
PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical group NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 abstract 3
125000004103 aminoalkyl group Chemical group 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
239000012948 isocyanate Substances 0.000 abstract 1
150000002513 isocyanates Chemical class 0.000 abstract 1
150000002540 isothiocyanates Chemical class 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
210000002700 urine Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Anesthesiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO880330A 1987-01-27 1988-01-26 Tetrahydrocannabinolderivater samt anvendelse derav ved immunoassay for paavisning av cannabinol-metabolitter NO171274C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/007,838 US4833073A (en)	1987-01-27	1987-01-27	Immunoassay for tetrahydrocannabinol metabolites

Publications (4)

Publication Number	Publication Date
NO880330D0 NO880330D0 (no)	1988-01-26
NO880330L NO880330L (no)	1988-07-28
NO171274B NO171274B (no)	1992-11-09
NO171274C true NO171274C (no)	1993-02-17

Family

ID=21728380

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO880330A NO171274C (no)	1987-01-27	1988-01-26	Tetrahydrocannabinolderivater samt anvendelse derav ved immunoassay for paavisning av cannabinol-metabolitter

Country Status (12)

Country	Link
US (1)	US4833073A (fr)
EP (1)	EP0276732B1 (fr)
JP (1)	JPH0819117B2 (fr)
AT (1)	ATE97895T1 (fr)
AU (1)	AU614733B2 (fr)
DE (1)	DE3885911T2 (fr)
DK (1)	DK37888A (fr)
ES (1)	ES2060610T3 (fr)
FI (1)	FI96685C (fr)
HK (1)	HK63595A (fr)
NO (1)	NO171274C (fr)
NZ (1)	NZ223289A (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5264373A (en) *	1987-02-17	1993-11-23	Abbott Laboratories	Fluorescence polarization immunoassay for tetrahydrocannabinoids
EP0392332A3 (fr) *	1989-04-12	1992-01-08	F. Hoffmann-La Roche Ag	Essai immunologique à polarisation de fluorescence et réactifs pour cet essai
US5001743A (en) *	1990-01-10	1991-03-19	Northern Telecom Limited	Method and apparatus for controlling a telephone answering device
IL99468A (en) *	1991-09-12	1997-09-30	Yissum Res Dev Co	(3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them
US5460944A (en) *	1991-10-28	1995-10-24	Boehringer Mannheim Gmbh	Storable protein solution
US5292899A (en) *	1991-11-27	1994-03-08	Synthetic Technology Corporation	Synthesis of 11-nor-Δ-9-tetrahydrocannabinol-9-carboxylic acid glucuronide
US5237057A (en) *	1992-04-06	1993-08-17	Biosite Diagnostics, Inc.	Tetrahydrocannabinol derivatives and protein and polypeptide tetrahydrocannabinol derivative conjugates and labels
US5315015A (en) *	1992-11-10	1994-05-24	Hoffmann-La Roche Inc.	Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same
US5817766A (en) *	1995-04-05	1998-10-06	Roche Diagnostic Systems, Inc.	Reagents for a cannabinoid immunoassay
US6162829A (en) *	1997-10-17	2000-12-19	Atlantic Pharmaceuticals, Inc.	(3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics
CA2340444A1 (fr) *	1998-05-04	1999-11-11	The University Of Connecticut	Cannabinoides specifiques au recepteur cb2
US7589220B2 (en)	1998-06-09	2009-09-15	University Of Connecticut	Inhibitors of the anandamide transporter
US7897598B2 (en)	1998-06-09	2011-03-01	Alexandros Makriyannis	Inhibitors of the anandamide transporter
US6248598B1 (en)	1998-09-17	2001-06-19	Stuart C. Bogema	Immunoassay that provides for both collection of saliva and assay of saliva for one or more analytes with visual readout
US7276613B1 (en)	1998-11-24	2007-10-02	University Of Connecticut	Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en)	1998-11-24	2007-01-09	University Of Connecticut	Cannabimimetic lipid amides as useful medications
US6566560B2 (en)	1999-03-22	2003-05-20	Immugen Pharmaceuticals, Inc.	Resorcinolic compounds
CN1377261A (zh)	1999-03-22	2002-10-30	免疫力药品有限公司	治疗免疫疾病
US6943266B1 (en)	1999-10-18	2005-09-13	University Of Connecticut	Bicyclic cannabinoid agonists for the cannabinoid receptor
US6900236B1 (en)	1999-10-18	2005-05-31	University Of Connecticut	Cannabimimetic indole derivatives
US7741365B2 (en)	1999-10-18	2010-06-22	University Of Connecticut	Peripheral cannabinoid receptor (CB2) selective ligands
US7393842B2 (en)	2001-08-31	2008-07-01	University Of Connecticut	Pyrazole analogs acting on cannabinoid receptors
WO2001028329A1 (fr)	1999-10-18	2001-04-26	University Of Connecticut	Ligands selectifs de recepteurs (cb2) de cannabinoides peripheriques
US8084467B2 (en)	1999-10-18	2011-12-27	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
US7119108B1 (en)	1999-10-18	2006-10-10	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
US6541510B2 (en) *	2000-09-28	2003-04-01	Immugen Pharmaceuticals, Inc.	Antiviral methods and compounds
AU2001296402A1 (en) *	2000-09-28	2002-04-08	Immugen Pharmaceuticals, Inc.	Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
US7329651B2 (en)	2001-01-26	2008-02-12	University Of Connecticut	Cannabimimetic ligands
WO2002060447A1 (fr)	2001-01-29	2002-08-08	University Of Connecticut	Aminoalkylindoles cannabimimetiques selectifs d'un recepteur
WO2003005960A2 (fr)	2001-07-13	2003-01-23	University Of Connecticut	Nouveaux cannabinoides bicycliques et tricycliques
WO2003035005A2 (fr)	2001-10-26	2003-05-01	University Of Connecticut	Heteroindanes: nouvelle classe de ligands cannabimimetiques efficaces
WO2003080043A1 (fr) *	2002-03-18	2003-10-02	Immugen Pharmaceuticals, Inc.	Preparations topiques de resorcinols et de cannabinoides et leurs procedes d'utilisation
AU2003265663A1 (en) *	2002-08-23	2004-03-11	University Of Connecticut	Keto cannabinoids with therapeutic indications
US7195882B2 (en) *	2003-06-03	2007-03-27	Roche Diagnostics Operations, Inc.	Monoclonal antibodies specific for buprenorphine and metabolites thereof
WO2005026178A2 (fr)	2003-07-01	2005-03-24	Roche Diagnostics Gmbh	Systeme de biocapteurs a affinite electrochimiques et procedes associes
US20060051824A1 (en) *	2004-09-03	2006-03-09	Haoyun An	Tetrahydrocannabinoid antigens and method of use
GB0725234D0 (en) *	2007-12-24	2008-02-06	Oxtex Ltd	Electrochemical assays
US10408786B2 (en)	2012-06-14	2019-09-10	ChemiSensor, LLP	Distributable chemical sampling and sensing system
US10254298B1 (en) *	2015-03-25	2019-04-09	National Technology & Engineering Solutions Of Sandia, Llc	Detection of metabolites for controlled substances
US10458963B2 (en)	2016-06-08	2019-10-29	Kathleen Stitzlein	Quantitative HPTLC cannabinoid field testing device and method
US10981174B1 (en)	2016-08-04	2021-04-20	National Technology & Engineering Solutions Of Sandia, Llc	Protein and nucleic acid detection for microfluidic devices
US12545694B2 (en)	2020-01-08	2026-02-10	Chengdu Baiyu Pharmaceutical Co., Ltd.	Cannabidiol derivatives, preparation method thereof and use thereof
CN113087743B (zh) *	2020-01-08	2023-04-28	成都百裕制药股份有限公司	四氢大麻酚衍生物及其制备方法和在医药上的应用
CN119534358A (zh) *	2023-08-28	2025-02-28	广州达安基因股份有限公司	Δ9-四氢大麻酚的检测试剂及其制备方法和检测方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3649650A (en) *	1970-02-13	1972-03-14	Little Inc A	Novel derivatives of tetrahydro-cannabinol
IL39323A (en) *	1971-05-14	1975-08-31	Syva Co	Highly sensitive assay method employing an enzyme for amplification
US4438207A (en) *	1979-09-26	1984-03-20	Hoffmann-La Roche Inc.	Radioimmunoassay for cannabinoids
US4378428A (en) *	1981-03-30	1983-03-29	Baker Instruments Corporation	Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays
US4652681A (en) *	1982-04-15	1987-03-24	Drug Science Foundation	Aminoalkoxy derivatives of propranolol for immunoassay applications
US4650771A (en) *	1983-11-04	1987-03-17	Miles Laboratories, Inc.	Immunogens, antibodies, labeled conjugates, and related derivatives for lidocaine and analogs thereof

1987
- 1987-01-27 US US07/007,838 patent/US4833073A/en not_active Expired - Lifetime
1988
- 1988-01-20 DE DE88100732T patent/DE3885911T2/de not_active Expired - Lifetime
- 1988-01-20 ES ES88100732T patent/ES2060610T3/es not_active Expired - Lifetime
- 1988-01-20 AT AT88100732T patent/ATE97895T1/de not_active IP Right Cessation
- 1988-01-20 EP EP88100732A patent/EP0276732B1/fr not_active Expired - Lifetime
- 1988-01-25 JP JP63012742A patent/JPH0819117B2/ja not_active Expired - Fee Related
- 1988-01-26 NO NO880330A patent/NO171274C/no unknown
- 1988-01-26 DK DK037888A patent/DK37888A/da not_active Application Discontinuation
- 1988-01-26 FI FI880332A patent/FI96685C/fi not_active IP Right Cessation
- 1988-01-26 NZ NZ223289A patent/NZ223289A/xx unknown
- 1988-01-27 AU AU11115/88A patent/AU614733B2/en not_active Ceased
1995
- 1995-04-27 HK HK63595A patent/HK63595A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU1111588A (en)	1988-07-28
JPS63192770A (ja)	1988-08-10
FI880332A7 (fi)	1988-07-28
FI96685B (fi)	1996-04-30
HK63595A (en)	1995-05-05
DE3885911T2 (de)	1994-03-24
NZ223289A (en)	1989-06-28
NO880330D0 (no)	1988-01-26
FI880332A0 (fi)	1988-01-26
FI96685C (fi)	1996-08-12
DK37888A (da)	1988-07-28
US4833073A (en)	1989-05-23
JPH0819117B2 (ja)	1996-02-28
EP0276732A2 (fr)	1988-08-03
EP0276732A3 (en)	1989-02-22
AU614733B2 (en)	1991-09-12
DE3885911D1 (de)	1994-01-13
ES2060610T3 (es)	1994-12-01
NO880330L (no)	1988-07-28
NO171274B (no)	1992-11-09
DK37888D0 (da)	1988-01-26
ATE97895T1 (de)	1993-12-15
EP0276732B1 (fr)	1993-12-01

Publication	Publication Date	Title
NZ223289A (en)	1989-06-28	Tetrahydrocannabinol derivatives and use in immunoassay
ATE88338T1 (de)	1993-05-15	Vernetzungsmittel zur haarbehandlung.
DE69609108D1 (de)	2000-08-10	Verbesserte Immunoessayreagenzien zum Nachweis von Kannabinoiden
KR910007935A (ko)	1991-05-30	세고리형 카르바페넴 화합물
ES2182054T3 (es)	2003-03-01	Derivados de oxazol, su produccion y uso.
PT89759A (pt)	1989-10-04	Processo para a preparacao de derivados especiais quimiluminescentes de acridina e de meios de ensaio imunoluminescentes que os contem
ATE72831T1 (de)	1992-03-15	Konjugate von glucose-6-phosphat-dehydrogenase, ihre herstellung und verwendung.
KR890009962A (ko)	1989-08-05	매뉴마이신 유도체, 이의 제조방법 및 용도
DK37691A (da)	1991-03-01	Substituerede beta-diketoner, farmaceutiske midler indeholdende disse forbindelser samt anvendelse deraf
ES2157292T3 (es)	2001-08-16	Inhibidores 6-azaindol de la tromboxano sintasa.
ES2136346T3 (es)	1999-11-16	Procedimiento para la determinacion cuantitativa de peroxidos, una substancia que reacciona con peroxido, o un derivado de pirazolopiridopiridazina.
KR900003142A (ko)	1990-03-23	환형 황을 함유하는 화합물
ATE38675T1 (de)	1988-12-15	Phosphatesterderivate und ihre verwendung als anti-krebsmittel.
DK21287A (da)	1987-07-18	Penemderivater
EP0349274A3 (en)	1990-03-21	Photographic dot enhancing compositions and methods for their use
KR890008151A (ko)	1989-07-10	키놀린 카르복산의 유도체
DK0381628T3 (da)	1995-05-01	Glycocyamidinderivater
FR2566720B3 (fr)	1986-12-26	Support d'articles tels que bouteilles, cassettes, adaptable aux portes de vehicules
FI901046A0 (fi)	1990-03-01	Stabilisering av polyprenylfoereningen.
IE830819L (en)	1983-10-12	Dithiolan derivatives
KR890002190A (ko)	1989-04-08	퀴놀린 카르본산 유도체
KR890016032A (ko)	1989-11-28	푸란 유도체의 제조방법
KR870002148A (ko)	1987-03-30	세팔로스포린 유도체의 제조방법
KR900000348A (ko)	1990-01-30	N-술파모일-3-[(2-구아니디노티아졸-4-일)메틸티오]프로피온아미딘의 제조방법