NO172063C - Fremgangsmaate ved stabilisering av ekstra-kromosomale elementer i bakterier under dyrking og fremgangsmaate for fremstilling av et oensket produkt i transformerte bakterier - Google Patents

Fremgangsmaate ved stabilisering av ekstra-kromosomale elementer i bakterier under dyrking og fremgangsmaate for fremstilling av et oensket produkt i transformerte bakterier

Info

Publication number
NO172063C
NO172063C NO854966A NO854966A NO172063C NO 172063 C NO172063 C NO 172063C NO 854966 A NO854966 A NO 854966A NO 854966 A NO854966 A NO 854966A NO 172063 C NO172063 C NO 172063C
Authority
NO
Norway
Prior art keywords
extra
chromosomal
gene
bacteries
procedure
Prior art date
Application number
NO854966A
Other languages
English (en)
Norwegian (no)
Other versions
NO172063B (no
NO854966L (no
Inventor
Boerge Krag Diderichsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO854966L publication Critical patent/NO854966L/no
Publication of NO172063B publication Critical patent/NO172063B/no
Publication of NO172063C publication Critical patent/NO172063C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Saccharide Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Mushroom Cultivation (AREA)
  • Discharge Heating (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
NO854966A 1984-12-12 1985-12-11 Fremgangsmaate ved stabilisering av ekstra-kromosomale elementer i bakterier under dyrking og fremgangsmaate for fremstilling av et oensket produkt i transformerte bakterier NO172063C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK594084A DK594084A (da) 1984-12-12 1984-12-12 Fremgangsmaade til stabilisering af extra-chromosomale elementer i bakterier under dyrkning

Publications (3)

Publication Number Publication Date
NO854966L NO854966L (no) 1986-06-13
NO172063B NO172063B (no) 1993-02-22
NO172063C true NO172063C (no) 1993-06-02

Family

ID=8146313

Family Applications (1)

Application Number Title Priority Date Filing Date
NO854966A NO172063C (no) 1984-12-12 1985-12-11 Fremgangsmaate ved stabilisering av ekstra-kromosomale elementer i bakterier under dyrking og fremgangsmaate for fremstilling av et oensket produkt i transformerte bakterier

Country Status (10)

Country Link
US (1) US4920048A (de)
EP (1) EP0185512B1 (de)
JP (2) JP2576970B2 (de)
AT (1) ATE55413T1 (de)
AU (1) AU592542B2 (de)
CA (1) CA1292197C (de)
DE (1) DE3579133D1 (de)
DK (1) DK594084A (de)
FI (1) FI85876C (de)
NO (1) NO172063C (de)

Families Citing this family (36)

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US5198343A (en) * 1986-08-05 1993-03-30 Transgene, S.A. Method for expressing a heterologous protein in a dapD- mutant of E. coli and the strain obtained
CA1340903C (fr) * 1986-08-05 2000-02-22 Transgene S.A. Procede de stabilisation d'un plasmide contenu dans une soche bacterienne et souche obtenue
FR2602792B1 (fr) * 1986-08-05 1989-10-20 Transgene Sa Procede de stabilisation d'un plasmide contenu dans une souche bacterienne et souche obtenue
FR2618159B2 (fr) * 1987-07-15 1990-02-02 Transgene Sa Procede de stabilisation d'un plasmide contenu dans une souche bacterienne et souche obtenue
DE3853683T2 (de) * 1987-10-07 1995-08-31 Univ Washington Verfahren zur erhaltung eines erwünschten rekombinanten gens in einer genetischen zellpopulation.
HU200796B (en) * 1988-07-14 1990-08-28 Richter Gedeon Vegyeszet Process for producing expression vectors ensuring insertion of nucleotide sequences into e. coli chromosome
RU2099418C1 (ru) * 1991-11-21 1997-12-20 Лонца Аг Фрагмент днк, обеспечивающий использование бетаина, рекомбинантная плазмидная днк с фрагментом днк, обеспечивающим использование бетаина, штамм бактерий rhizobium/agrobacterium, предназначенный для стабильного хранения плазмиды с фрагментом днк, способ получения штамма бактерий
JPH08500734A (ja) * 1992-08-18 1996-01-30 デュファル インターナショナル リサーチ ベスローテン フェンノートシャップ 気管支敗血症菌（Ｂｏｒｄｅｔｅｌｌａ ｂｒｏｎｃｈｉｓｅｐｔｉｃａ）ワクチン
US5885823A (en) * 1995-06-05 1999-03-23 Nobl Laboratories, Inc. Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents
US5714375A (en) * 1995-06-05 1998-02-03 Nobl Laboratories, Inc. Ileal symbiont intracellularis propagation in suspended host cells
GB9518395D0 (en) * 1995-09-08 1995-11-08 Therexsys Ltd Plasmid stabilization
US6743780B1 (en) 1995-09-08 2004-06-01 Cobra Biologics Limited Plasmid stabilization
US5922583A (en) * 1995-10-17 1999-07-13 Biostar Inc. Methods for production of recombinant plasmids
US6291245B1 (en) 1998-07-15 2001-09-18 Roche Diagnostics Gmbh Host-vector system
EP0972838B1 (de) * 1998-07-15 2004-09-15 Roche Diagnostics GmbH Escherichia coli Wirt/Vektorsystem basierend auf einer antibiotikafreien Selektion durch Komplementation einer Auxotrophie
JP3958884B2 (ja) 1998-09-11 2007-08-15 株式会社林原生物化学研究所 非還元性糖質生成酵素及びトレハロース遊離酵素ならびに該酵素を用いる糖質の製造方法
AU2001265835A1 (en) 2000-06-23 2002-01-08 Novozymes A/S Method for stable chromosomal multi-copy integration of genes
CN1322138C (zh) * 2000-06-23 2007-06-20 诺维信公司 用于基因的稳定的染色体多拷贝整合的方法
WO2005052151A1 (en) * 2003-11-19 2005-06-09 Dow Global Technologies Inc. Improved protein expression systems
JP2006067884A (ja) * 2004-09-01 2006-03-16 Kao Corp 組換えバチルス属細菌
JP2006067883A (ja) * 2004-09-01 2006-03-16 Kao Corp 組換えバチルス属細菌
US7923231B2 (en) * 2004-12-17 2011-04-12 Cargill, Incorporated Production of glucuronic acid using myo-inositol oxygenase from cryptococcus neoformans
US8834891B2 (en) * 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
US8398994B2 (en) * 2005-07-15 2013-03-19 Boehringer Ingelheim Vetmedica, Inc. Lawsonia vaccine and methods of use thereof
CA2624923C (en) * 2005-10-06 2016-06-07 Franck Martin Novel transformation selection system comprising pyrc gene complementation
US8470336B2 (en) * 2006-05-25 2013-06-25 Boehringer Ingelheim Vetmedica, Inc. Vaccination of young animals against Lawsonia intracellularis infections
DE102007021001A1 (de) 2007-05-04 2008-11-06 Ab Enzymes Gmbh Expressionssystem zur antibiotikafreien Produktion von Polypeptiden
WO2009037262A2 (en) 2007-09-17 2009-03-26 Boehringer Ingelheim Vetmedica, Inc. Method of preventing early lawsonia intracellularis infections
AU2010247938B2 (en) 2009-05-11 2016-02-18 Pelican Technology Holdings, Inc. Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein
CN108463546B (zh) 2015-12-11 2022-03-11 瓦克化学股份公司 用于无抗生素发酵制备低分子量物质和蛋白质的微生物菌株和方法
DE18305781T1 (de) 2018-06-20 2020-09-17 Eligo Bioscience Bakterielles freisetzungsvehikel, verfahren zur herstellung und verwendungen davon
US12098372B2 (en) 2019-12-30 2024-09-24 Eligo Bioscience Microbiome modulation of a host by delivery of DNA payloads with minimized spread
US11746352B2 (en) 2019-12-30 2023-09-05 Eligo Bioscience Microbiome modulation of a host by delivery of DNA payloads with minimized spread
WO2022144381A1 (en) 2020-12-30 2022-07-07 Eligo Bioscience Microbiome modulation of a host by delivery of dna payloads with minimized spread
US11739304B2 (en) 2021-05-12 2023-08-29 Eligo Bioscience Production of lytic phages
GB202304540D0 (en) 2023-03-28 2023-05-10 Univ Tartu Method of biosynthesis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE48385B1 (en) * 1978-08-11 1984-12-26 Univ California Synthesis of a eucaryotic protein by a microorganism
US4506013A (en) * 1980-10-03 1985-03-19 Eli Lilly And Company Stabilizing and selecting recombinant DNA host cells
US4436815A (en) * 1981-11-27 1984-03-13 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cells
DK410783D0 (da) * 1982-09-16 1983-09-09 Benzon A Salfred Fremgangsmade til stabilisering af plasmider
US4595660A (en) * 1983-03-02 1986-06-17 University Of Delaware Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis, mutants and substantially stably transformed mutants of Bacillus subtilis, and methods for utilizing the transformed mutants
JPS59205983A (ja) * 1983-04-28 1984-11-21 ジエネツクス・コ−ポレイシヨン 異種遺伝子を原核微生物で発現させる方法
AU600885B2 (en) * 1984-05-25 1990-08-30 Zymogenetics Inc. Stable DNA constructs

Also Published As

Publication number Publication date
JPS61139392A (ja) 1986-06-26
NO172063B (no) 1993-02-22
DK594084D0 (da) 1984-12-12
FI854893A7 (fi) 1986-06-13
EP0185512A1 (de) 1986-06-25
FI85876B (fi) 1992-02-28
DK594084A (da) 1986-06-13
AU592542B2 (en) 1990-01-18
JPH0686669A (ja) 1994-03-29
ATE55413T1 (de) 1990-08-15
DE3579133D1 (de) 1990-09-13
CA1292197C (en) 1991-11-19
NO854966L (no) 1986-06-13
FI854893A0 (fi) 1985-12-11
JP2576970B2 (ja) 1997-01-29
EP0185512B1 (de) 1990-08-08
FI85876C (fi) 1992-06-10
JP2571338B2 (ja) 1997-01-16
US4920048A (en) 1990-04-24
AU5108185A (en) 1986-06-19

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Free format text: LAPSED IN JUNE 2002