NO173827C - Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinoxaliner - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinoxaliner

Info

Publication number: NO173827C
Authority: NO; Norway
Prior art keywords: imidazoquinoxalins; preparation; therapeutically active; analogous procedures; novel
Prior art date: 1988-11-10

Application number

NO894474A

Other languages

English (en)

Norwegian (no)

Other versions

NO173827B (no

NO894474D0 (no

NO894474L (no

Inventor

Frank Waetjen

Holger Claus Hansen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-11-10

Filing date

1989-11-09

Publication date

1994-02-09

1989-11-09 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1989-11-09 Publication of NO894474D0 publication Critical patent/NO894474D0/no

1990-05-11 Publication of NO894474L publication Critical patent/NO894474L/no

1993-11-01 Publication of NO173827B publication Critical patent/NO173827B/no

1994-02-09 Publication of NO173827C publication Critical patent/NO173827C/no

Links

YELMWJNXDALKFE-UHFFFAOYSA-N 3h-imidazo[4,5-f]quinoxaline Chemical class N1=CC=NC2=C(NC=N3)C3=CC=C21 YELMWJNXDALKFE-UHFFFAOYSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title 1
-1 -tert-butyl compound Chemical class 0.000 abstract 1
238000001311 chemical methods and process Methods 0.000 abstract 1
230000020335 dealkylation Effects 0.000 abstract 1
238000006900 dealkylation reaction Methods 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO894474A 1988-11-10 1989-11-09 Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinoxaliner NO173827C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK626288A DK626288D0 (da)	1988-11-10	1988-11-10	Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen

Publications (4)

Publication Number	Publication Date
NO894474D0 NO894474D0 (no)	1989-11-09
NO894474L NO894474L (no)	1990-05-11
NO173827B NO173827B (no)	1993-11-01
NO173827C true NO173827C (no)	1994-02-09

Family

ID=8148369

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO894474A NO173827C (no)	1988-11-10	1989-11-09	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinoxaliner

Country Status (17)

Country	Link
US (1)	US4999353A (de)
EP (1)	EP0368652B1 (de)
JP (1)	JPH02178285A (de)
AT (1)	ATE119162T1 (de)
AU (1)	AU622941B2 (de)
CA (1)	CA2002624A1 (de)
DE (1)	DE68921418T2 (de)
DK (1)	DK626288D0 (de)
ES (1)	ES2068903T3 (de)
FI (1)	FI92931C (de)
GR (1)	GR3015718T3 (de)
IE (1)	IE68939B1 (de)
IL (1)	IL92055A (de)
NO (1)	NO173827C (de)
NZ (1)	NZ231321A (de)
PT (1)	PT92279B (de)
ZA (1)	ZA898051B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK588489D0 (da) *	1989-11-22	1989-11-22	Ferrosan As	Heterocykliske forbindelser, deres fremstilling og anvendelse
KR100207360B1 (ko) *	1991-06-14	1999-07-15	돈 더블유. 슈미츠	이미다조[1,5,-a]퀸옥살린
AU4035893A (en) *	1991-12-17	1993-07-19	Upjohn Company, The	3-substituted imidazo (1,5-a) and imidazo (1,5-a)-triazolo (1,5-c) quinoxalines and quinazolines with cns activity
DE4228095A1 (de) *	1992-08-24	1994-03-03	Asta Medica Ag	Neue 4,5-Dihydro-4-oxo-pyrrolo[1,2-a]chinoxaline und entsprechende Aza-analoga und Verfahren zu deren Herstellung
FR2696466B1 (fr) *	1992-10-02	1994-11-25	Rhone Poulenc Rorer Sa	Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant.
US5792766A (en)	1996-03-13	1998-08-11	Neurogen Corporation	Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
JP4042925B2 (ja) *	1996-11-20	2008-02-06	シスメックス株式会社	幼若白血球の分類計数法
US20040180898A1 (en) *	2003-03-03	2004-09-16	Bang-Chi Chen	Processes for preparing imidazoquinoxalinones, heterocyclic-substituted imidazopyrazinones, imidazoquinoxalines and heterocyclic-substituted imidazopyrazines
CN108473495B (zh)	2015-11-20	2022-04-12	福马治疗有限公司	作为泛素-特异性蛋白酶1抑制剂的嘌呤酮

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4440929A (en) *	1981-07-16	1984-04-03	Usv Pharmaceutical Corporation	Imidazoquinoxaline compounds
DK476885D0 (da) *	1985-10-17	1985-10-17	Ferrosan As	Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
ATE44381T1 (de) *	1985-10-17	1989-07-15	Ferrosan As	Heterocyclische verbindungen und ihre herstellung und verwendung.
DK155524C (da) *	1987-03-18	1989-09-11	Ferrosan As	Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
DK160876C (da) *	1987-12-08	1991-10-14	Novo Nordisk As	Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
IL90315A0 (en) *	1988-06-01	1989-12-15	Ferrosan As	Imidazoquinoxaline compounds,their preparation and pharmaceutical compositions containing them

1988
- 1988-11-10 DK DK626288A patent/DK626288D0/da not_active Application Discontinuation
1989
- 1989-10-19 IL IL9205589A patent/IL92055A/en not_active IP Right Cessation
- 1989-10-20 IE IE337489A patent/IE68939B1/en not_active IP Right Cessation
- 1989-10-24 ZA ZA898051A patent/ZA898051B/xx unknown
- 1989-11-03 AU AU44393/89A patent/AU622941B2/en not_active Ceased
- 1989-11-06 FI FI895257A patent/FI92931C/fi not_active IP Right Cessation
- 1989-11-07 JP JP1288081A patent/JPH02178285A/ja active Pending
- 1989-11-08 NZ NZ231321A patent/NZ231321A/xx unknown
- 1989-11-08 US US07/433,668 patent/US4999353A/en not_active Expired - Fee Related
- 1989-11-09 CA CA002002624A patent/CA2002624A1/en not_active Abandoned
- 1989-11-09 ES ES89311587T patent/ES2068903T3/es not_active Expired - Lifetime
- 1989-11-09 EP EP89311587A patent/EP0368652B1/de not_active Expired - Lifetime
- 1989-11-09 NO NO894474A patent/NO173827C/no unknown
- 1989-11-09 AT AT89311587T patent/ATE119162T1/de not_active IP Right Cessation
- 1989-11-09 DE DE68921418T patent/DE68921418T2/de not_active Expired - Fee Related
- 1989-11-10 PT PT92279A patent/PT92279B/pt not_active IP Right Cessation
1995
- 1995-04-10 GR GR950400849T patent/GR3015718T3/el unknown

Also Published As

Publication number	Publication date
US4999353A (en)	1991-03-12
CA2002624A1 (en)	1990-05-10
PT92279B (pt)	1995-08-09
NO173827B (no)	1993-11-01
DE68921418T2 (de)	1995-07-13
JPH02178285A (ja)	1990-07-11
FI895257A0 (fi)	1989-11-06
EP0368652B1 (de)	1995-03-01
IL92055A0 (en)	1990-07-12
PT92279A (pt)	1990-05-31
AU622941B2 (en)	1992-04-30
DK626288D0 (da)	1988-11-10
ATE119162T1 (de)	1995-03-15
DE68921418D1 (de)	1995-04-06
EP0368652A1 (de)	1990-05-16
ES2068903T3 (es)	1995-05-01
IE893374L (en)	1990-05-10
IE68939B1 (en)	1996-07-24
ZA898051B (en)	1990-08-29
NO894474D0 (no)	1989-11-09
AU4439389A (en)	1990-05-17
NZ231321A (en)	1991-10-25
FI92931B (fi)	1994-10-14
NO894474L (no)	1990-05-11
FI92931C (fi)	1995-01-25
IL92055A (en)	1994-01-25
GR3015718T3 (en)	1995-07-31

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