PT92279A - Processo de preparacao de imidazoquinoxalinas - Google Patents

Processo de preparacao de imidazoquinoxalinas

Info

Publication number: PT92279A
Authority: PT; Portugal
Prior art keywords: imidazoquinoxalinas; preparation process; novel; vaulable; imidazoquinoxalines
Prior art date: 1988-11-10

Application number

PT92279A

Other languages

English (en)

Other versions

PT92279B (pt

Inventor

Holger Claus Hansen

Frank Waetjen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-11-10

Filing date

1989-11-10

Publication date

1990-05-31

1989-11-10 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1990-05-31 Publication of PT92279A publication Critical patent/PT92279A/pt

1995-08-09 Publication of PT92279B publication Critical patent/PT92279B/pt

Links

238000002360 preparation method Methods 0.000 title 1
-1 -tert-butyl compound Chemical class 0.000 abstract 1
YELMWJNXDALKFE-UHFFFAOYSA-N 3h-imidazo[4,5-f]quinoxaline Chemical group N1=CC=NC2=C(NC=N3)C3=CC=C21 YELMWJNXDALKFE-UHFFFAOYSA-N 0.000 abstract 1
238000001311 chemical methods and process Methods 0.000 abstract 1
230000020335 dealkylation Effects 0.000 abstract 1
238000006900 dealkylation reaction Methods 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

PT92279A 1988-11-10 1989-11-10 Processo de preparacao de imidazoquinoxalinas PT92279B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK626288A DK626288D0 (da)	1988-11-10	1988-11-10	Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen

Publications (2)

Publication Number	Publication Date
PT92279A true PT92279A (pt)	1990-05-31
PT92279B PT92279B (pt)	1995-08-09

Family

ID=8148369

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT92279A PT92279B (pt)	1988-11-10	1989-11-10	Processo de preparacao de imidazoquinoxalinas

Country Status (17)

Country	Link
US (1)	US4999353A (pt)
EP (1)	EP0368652B1 (pt)
JP (1)	JPH02178285A (pt)
AT (1)	ATE119162T1 (pt)
AU (1)	AU622941B2 (pt)
CA (1)	CA2002624A1 (pt)
DE (1)	DE68921418T2 (pt)
DK (1)	DK626288D0 (pt)
ES (1)	ES2068903T3 (pt)
FI (1)	FI92931C (pt)
GR (1)	GR3015718T3 (pt)
IE (1)	IE68939B1 (pt)
IL (1)	IL92055A (pt)
NO (1)	NO173827C (pt)
NZ (1)	NZ231321A (pt)
PT (1)	PT92279B (pt)
ZA (1)	ZA898051B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK588489D0 (da) *	1989-11-22	1989-11-22	Ferrosan As	Heterocykliske forbindelser, deres fremstilling og anvendelse
AU657986B2 (en) *	1991-06-14	1995-03-30	Pharmacia & Upjohn Company	Imidazo(1,5-a)quinoxalines
AU4035893A (en) *	1991-12-17	1993-07-19	Upjohn Company, The	3-substituted imidazo (1,5-a) and imidazo (1,5-a)-triazolo (1,5-c) quinoxalines and quinazolines with cns activity
DE4228095A1 (de) *	1992-08-24	1994-03-03	Asta Medica Ag	Neue 4,5-Dihydro-4-oxo-pyrrolo[1,2-a]chinoxaline und entsprechende Aza-analoga und Verfahren zu deren Herstellung
FR2696466B1 (fr) *	1992-10-02	1994-11-25	Rhone Poulenc Rorer Sa	Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant.
US5792766A (en)	1996-03-13	1998-08-11	Neurogen Corporation	Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
JP4042925B2 (ja) *	1996-11-20	2008-02-06	シスメックス株式会社	幼若白血球の分類計数法
US20040180898A1 (en) *	2003-03-03	2004-09-16	Bang-Chi Chen	Processes for preparing imidazoquinoxalinones, heterocyclic-substituted imidazopyrazinones, imidazoquinoxalines and heterocyclic-substituted imidazopyrazines
US10189841B2 (en)	2015-11-20	2019-01-29	Forma Therapeutics, Inc.	Purinones as ubiquitin-specific protease 1 inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4440929A (en) *	1981-07-16	1984-04-03	Usv Pharmaceutical Corporation	Imidazoquinoxaline compounds
DK476885D0 (da) *	1985-10-17	1985-10-17	Ferrosan As	Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
CA1297099C (en) *	1985-10-17	1992-03-10	Frank Watjen	Quinazoline compounds and their preparation and use
DK155524C (da) *	1987-03-18	1989-09-11	Ferrosan As	Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
DK160876C (da) *	1987-12-08	1991-10-14	Novo Nordisk As	Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
IL90315A0 (en) *	1988-06-01	1989-12-15	Ferrosan As	Imidazoquinoxaline compounds,their preparation and pharmaceutical compositions containing them

1988
- 1988-11-10 DK DK626288A patent/DK626288D0/da not_active Application Discontinuation
1989
- 1989-10-19 IL IL9205589A patent/IL92055A/en not_active IP Right Cessation
- 1989-10-20 IE IE337489A patent/IE68939B1/en not_active IP Right Cessation
- 1989-10-24 ZA ZA898051A patent/ZA898051B/xx unknown
- 1989-11-03 AU AU44393/89A patent/AU622941B2/en not_active Ceased
- 1989-11-06 FI FI895257A patent/FI92931C/fi not_active IP Right Cessation
- 1989-11-07 JP JP1288081A patent/JPH02178285A/ja active Pending
- 1989-11-08 US US07/433,668 patent/US4999353A/en not_active Expired - Fee Related
- 1989-11-08 NZ NZ231321A patent/NZ231321A/xx unknown
- 1989-11-09 AT AT89311587T patent/ATE119162T1/de not_active IP Right Cessation
- 1989-11-09 NO NO894474A patent/NO173827C/no unknown
- 1989-11-09 EP EP89311587A patent/EP0368652B1/en not_active Expired - Lifetime
- 1989-11-09 CA CA002002624A patent/CA2002624A1/en not_active Abandoned
- 1989-11-09 DE DE68921418T patent/DE68921418T2/de not_active Expired - Fee Related
- 1989-11-09 ES ES89311587T patent/ES2068903T3/es not_active Expired - Lifetime
- 1989-11-10 PT PT92279A patent/PT92279B/pt not_active IP Right Cessation
1995
- 1995-04-10 GR GR950400849T patent/GR3015718T3/el unknown

Also Published As

Publication number	Publication date
ZA898051B (en)	1990-08-29
NO173827C (no)	1994-02-09
IE893374L (en)	1990-05-10
IL92055A (en)	1994-01-25
AU4439389A (en)	1990-05-17
ATE119162T1 (de)	1995-03-15
DE68921418T2 (de)	1995-07-13
PT92279B (pt)	1995-08-09
EP0368652A1 (en)	1990-05-16
EP0368652B1 (en)	1995-03-01
JPH02178285A (ja)	1990-07-11
FI92931C (fi)	1995-01-25
NO894474D0 (no)	1989-11-09
DE68921418D1 (de)	1995-04-06
IL92055A0 (en)	1990-07-12
FI92931B (fi)	1994-10-14
AU622941B2 (en)	1992-04-30
IE68939B1 (en)	1996-07-24
ES2068903T3 (es)	1995-05-01
NO894474L (no)	1990-05-11
FI895257A0 (fi)	1989-11-06
NO173827B (no)	1993-11-01
GR3015718T3 (en)	1995-07-31
US4999353A (en)	1991-03-12
NZ231321A (en)	1991-10-25
DK626288D0 (da)	1988-11-10
CA2002624A1 (en)	1990-05-10

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Legal Events

Date

Code

Title

Description

1995-08-09

FG3A

Patent granted, date of granting

Effective date: 19950403

2000-02-29

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991031