NO174215C - Fremgangsmåte for modulering av animalske cellulære responser in vitro med preparater inneholdende 8-substituerte guaninderivater - Google Patents

Fremgangsmåte for modulering av animalske cellulære responser in vitro med preparater inneholdende 8-substituerte guaninderivater

Info

Publication number: NO174215C
Authority: NO; Norway
Prior art keywords: vitro; preparations containing; cellular responses; substituted guanine; guanine derivatives
Prior art date: 1982-11-09

Application number

NO842765A

Other languages

English (en)

Norwegian (no)

Other versions

NO174215B (no

NO842765L (no

Inventor

Michael G Goodman

William O Weigle

Original Assignee

Scripps Clinic Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-11-09

Filing date

1984-07-06

Publication date

1994-03-30

1982-11-09 Priority claimed from US06/439,846 external-priority patent/US4539205A/en

1984-07-06 Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res

1984-07-06 Publication of NO842765L publication Critical patent/NO842765L/no

1993-12-20 Publication of NO174215B publication Critical patent/NO174215B/no

1994-03-30 Publication of NO174215C publication Critical patent/NO174215C/no

Links

230000036755 cellular response Effects 0.000 title 1
UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical class O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 title 1
238000000338 in vitro Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
238000002360 preparation method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

NO842765A 1982-11-09 1984-07-06 Fremgangsmåte for modulering av animalske cellulære responser in vitro med preparater inneholdende 8-substituerte guaninderivater NO174215C (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US06/439,846 US4539205A (en)	1982-11-09	1982-11-09	Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
US06/546,679 US4643992A (en)	1982-11-09	1983-11-01	Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
PCT/US1983/001722 WO1984001898A1 (fr)	1982-11-09	1983-11-07	Modulation des reponses cellulaires animales par des compositions contenant des derives de la guanine substitues en position 8

Publications (3)

Publication Number	Publication Date
NO842765L NO842765L (no)	1984-07-06
NO174215B NO174215B (no)	1993-12-20
NO174215C true NO174215C (no)	1994-03-30

Family

ID=27032191

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO842765A NO174215C (no)	1982-11-09	1984-07-06	Fremgangsmåte for modulering av animalske cellulære responser in vitro med preparater inneholdende 8-substituerte guaninderivater

Country Status (15)

Country	Link
US (1)	US4643992A (fr)
EP (1)	EP0112632B1 (fr)
AU (1)	AU568325B2 (fr)
CA (1)	CA1236401A (fr)
DE (1)	DE3382156D1 (fr)
DK (1)	DK167898B1 (fr)
ES (1)	ES527138A0 (fr)
FI (1)	FI87733C (fr)
GR (1)	GR78733B (fr)
IE (1)	IE56701B1 (fr)
IL (1)	IL70164A (fr)
NO (1)	NO174215C (fr)
NZ (1)	NZ206208A (fr)
PT (1)	PT77636B (fr)
WO (1)	WO1984001898A1 (fr)

Families Citing this family (47)

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US4849411A (en) *	1982-11-09	1989-07-18	Scripps Clinic And Research Foundation	Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
US5476659A (en) *	1982-11-09	1995-12-19	The Scripps Research Institute	Cancerous B cell treatment using substituted nucleoside derivatives
US5166141A (en) *	1983-11-01	1992-11-24	Scripps Clinic And Research Foundation	Immunostimulating 7-deaza-7-oxa- and 7-deaza-7-oxo-analogs of 8-substituted-guanine-9-(1'-beta-D-aldoglycosidyl) derivatives and methods of treating test animals
US5093318A (en) *	1983-11-01	1992-03-03	Scripps Clinic And Research Foundation	Immunostimulating guanosine derivatives and their pharmaceutical compositions
US4900675A (en) *	1983-11-01	1990-02-13	Scripps Clinic And Research Foundation	Modulation of animal cellular responses with compositions containing isoxanthopterin-8-(1'-β-aldoglycosidyl) derivatives
FR2560212B1 (fr) *	1984-02-24	1989-12-29	Unicet	Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps
US5011828A (en) *	1985-11-15	1991-04-30	Michael Goodman	Immunostimulating guanine derivatives, compositions and methods
ZA869297B (en) *	1985-12-13	1987-11-25	Scripps Clinic Res	Modulation of animal cellular responses with compositions containing isoxanthopterin-8-(1'-beta-aldoglycosidyl)derivatives
US7307166B1 (en)	1987-10-28	2007-12-11	Wellstat Therapeutics Corporation	Oxpurine nucleosides and their congeners, and acyl, derivatives thereof, for improvement of hematopoiesis
US4880784A (en) *	1987-12-21	1989-11-14	Brigham Young University	Antiviral methods utilizing ribofuranosylthiazolo[4,5-d]pyrimdine derivatives
US4902985A (en) *	1988-02-25	1990-02-20	Raytheon Company	Microwave reflectiion amplifiers having increased bandwidth
GB2216416B (en) *	1988-03-11	1992-06-24	Sandoz Ltd	Nucleobase source for the stimulation of the immune system
ZA893063B (en) *	1988-04-27	1990-01-31	Immunomedics Inc	Improved radiotherapy
WO1994011003A1 (fr) *	1992-11-13	1994-05-26	The Scripps Research Institute	Traitement de lymphocytes b cancereux utilisant des derives de nucleosides substitues
US5441942A (en) *	1994-05-27	1995-08-15	The Scripps Research Institute	2'3'-dideoxy-2',3'-didehydro-7,8-disubstituted guanosines and their immunostimulative effect
US5786359A (en) *	1994-05-27	1998-07-28	The Scripps Research Institute	N9 alkyl or aralkyl derivatives of 7, 8-disubstituted guanines
US6338963B1 (en)	1994-07-25	2002-01-15	Neotherapeutics, Inc.	Use of carbon monoxide dependent guanylyl cyclase modifiers to stimulate neuritogenesis
US20030100520A1 (en) *	1997-01-21	2003-05-29	Philip Needleman	Immunological process and constructs for increasing the hdl cholesterol concentration by dna vaccination
US6303617B1 (en)	1998-05-04	2001-10-16	Neotherapeutics, Inc.	Serotonin-like 9-substituted hypoxanthine and methods of use
WO2000062803A2 (fr) *	1999-04-15	2000-10-26	Board Of Regents, The University Of Texas System	Ppgpp et pppgpp en tant qu'agents immunomodulatoires
US6288069B1 (en)	1999-11-16	2001-09-11	Neotherapeutics, Inc.	Use of 9-substituted hypoxanthine derivatives to stimulate regeneration of nervous tissue
US6407237B1 (en)	2001-02-21	2002-06-18	Neotherapeutics, Inc.	Crystal forms of 9-substituted hypoxanthine derivatives
US6849735B1 (en)	2000-06-23	2005-02-01	Merck Eprova Ag	Methods of synthesis for 9-substituted hypoxanthine derivatives
EP1790344B1 (fr)	2000-07-07	2011-02-23	Spectrum Pharmaceuticals, Inc.	Traitement de neuropathie périphérique induit par une pathologie et des tats connexés
US20030138769A1 (en) *	2000-08-16	2003-07-24	Birkett Ashley J.	Immunogenic HBc chimer particles having enhanced stability
US6759427B2 (en)	2001-04-20	2004-07-06	Spectrum Pharmaceuticals, Inc.	Synthesis and methods of use of tetrahydroindolone analogues and derivatives
EP1395262A4 (fr) *	2001-06-15	2006-04-12	Ribapharm Corp	Adjuvants vaccinaux nucleosidiques
US20030055249A1 (en) *	2001-07-17	2003-03-20	Fick David B.	Synthesis and methods of use of pyrimidine analogues and derivatives
US7361352B2 (en)	2001-08-15	2008-04-22	Acambis, Inc.	Influenza immunogen and vaccine
US20030175863A1 (en) *	2001-08-15	2003-09-18	Birkett Ashley J.	Influenza immunogen and vaccine
US7321033B2 (en) *	2001-11-27	2008-01-22	Anadys Pharmaceuticals, Inc.	3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
US7351413B2 (en) *	2002-02-21	2008-04-01	Lorantis, Limited	Stabilized HBc chimer particles as immunogens for chronic hepatitis
EP1667694B1 (fr)	2003-09-05	2010-04-28	Anadys Pharmaceuticals, Inc.	Ligands tlr7 destines au traitement du virus de l'hepatite c
CN102504001B (zh)	2004-12-17	2015-02-25	安那迪斯药品股份有限公司	3,5-二取代的和3,5,7-三取代的-3H-噁唑并以及3H-噻唑并[4,5-d]嘧啶-2-酮化合物及其前药
SG152296A1 (en)	2005-11-21	2009-05-29	Anadys Pharmaceuticals Inc	Novel process for the preparation of 5-amino-3h-thiazolo[4,5-d]pyrimidin-2- one
MX2008016518A (es) *	2006-06-22	2009-01-19	Anadys Pharmaceuticals Inc	Profarmacos de 5-amino-3-(3'-desoxi-beta-d-ribofuranosil)-tiazolo[ 4,5-d]pirimidin-2,7-dion.
WO2008011406A2 (fr)	2006-07-18	2008-01-24	Anadys Pharmaceuticals, Inc.	Promédicaments à groupes fonctionnels carbonate et carbamate de thiazolo [4,5-d] pyrimidines
EP2173376B1 (fr) *	2007-08-02	2015-03-25	Biondvax Pharmaceuticals Ltd.	Vaccins contre la grippe à multiples épitopes multimères
WO2009073179A2 (fr)	2007-12-03	2009-06-11	President And Fellows Of Harvard College	Antigènes de chlamydia
US20110236470A1 (en)	2008-12-03	2011-09-29	Yaffa Mizrachi Nebenzahl	GLUTAMYL tRNA SYNTHETASE (GtS) FRAGMENTS
ES2467108T3 (es)	2008-12-09	2014-06-11	Gilead Sciences, Inc.	Moduladores de receptores tipo toll
WO2011067758A2 (fr)	2009-12-02	2011-06-09	Protea Vaccine Technologies Ltd.	Fragments immunogènes et multimères pour protéines de streptococcus pneumoniae
CA2828068C (fr)	2011-02-22	2019-03-19	Biondvax Pharmaceuticals Ltd.	Polypeptides multimeres multi-epitopes utilises dans des vaccins contre la grippe saisonniere et pandemique
EP2833900B1 (fr)	2012-04-01	2018-09-19	Technion Research & Development Foundation Limited	Peptides d'inducteur de métalloprotéinase de matrice extracellulaire (emmprin) et anticorps de liaison
US10426828B2 (en)	2014-04-03	2019-10-01	Biondvax Pharmaceuticals Ltd.	Compositions of multimeric-multiepitope influenza polypeptides and their production
PT3166607T (pt)	2014-07-11	2022-12-07	Gilead Sciences Inc	Moduladores de receptores de tipo toll para o tratamento do vih
CA2960436C (fr)	2014-09-16	2021-01-05	Gilead Sciences, Inc.	Formes solides d'un modulateur de recepteurs de type toll

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Publication number	Priority date	Publication date	Assignee	Title
GB1174077A (en) *	1967-02-18	1969-12-10	Ajinomoto Kk	Process for Preparing 8-Mercaptopurine Derivatives

1983
- 1983-11-01 US US06/546,679 patent/US4643992A/en not_active Expired - Lifetime
- 1983-11-07 WO PCT/US1983/001722 patent/WO1984001898A1/fr not_active Ceased
- 1983-11-07 AU AU23302/84A patent/AU568325B2/en not_active Expired
- 1983-11-08 IL IL70164A patent/IL70164A/xx not_active IP Right Cessation
- 1983-11-08 ES ES527138A patent/ES527138A0/es active Granted
- 1983-11-08 CA CA000440679A patent/CA1236401A/fr not_active Expired
- 1983-11-08 IE IE2605/83A patent/IE56701B1/en not_active IP Right Cessation
- 1983-11-08 EP EP83306791A patent/EP0112632B1/fr not_active Expired - Lifetime
- 1983-11-08 DE DE8383306791T patent/DE3382156D1/de not_active Expired - Lifetime
- 1983-11-09 PT PT77636A patent/PT77636B/pt unknown
- 1983-11-09 GR GR72936A patent/GR78733B/el unknown
- 1983-11-09 NZ NZ206208A patent/NZ206208A/en unknown
1984
- 1984-07-06 NO NO842765A patent/NO174215C/no not_active IP Right Cessation
- 1984-07-06 DK DK334884A patent/DK167898B1/da not_active IP Right Cessation
- 1984-07-09 FI FI842748A patent/FI87733C/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI842748A0 (fi)	1984-07-09
ES8601301A1 (es)	1985-11-01
NO174215B (no)	1993-12-20
DK334884A (da)	1984-07-06
NZ206208A (en)	1987-03-31
DK167898B1 (da)	1994-01-03
ES527138A0 (es)	1985-11-01
FI87733C (fi)	1993-02-25
IL70164A (en)	1988-06-30
DE3382156D1 (de)	1991-03-14
FI842748L (fi)	1984-07-09
IL70164A0 (en)	1984-02-29
AU568325B2 (en)	1987-12-24
IE56701B1 (en)	1991-11-06
PT77636B (en)	1986-03-19
AU2330284A (en)	1984-06-04
CA1236401A (fr)	1988-05-10
EP0112632A2 (fr)	1984-07-04
PT77636A (en)	1983-12-01
EP0112632B1 (fr)	1991-02-06
NO842765L (no)	1984-07-06
GR78733B (fr)	1984-10-02
US4643992A (en)	1987-02-17
IE832605L (en)	1984-05-09
EP0112632A3 (en)	1985-01-23
WO1984001898A1 (fr)	1984-05-24
FI87733B (fi)	1992-11-13
DK334884D0 (da)	1984-07-06

Legal Events

Date	Code	Title	Description
2003-12-29	MK1K	Patent expired	Free format text: EXPIRED IN NOVEMBER 2003
2003-12-29	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN NOVEMBER 2003

Publication	Publication Date	Title
NO174215C (no)	1994-03-30	Fremgangsmåte for modulering av animalske cellulære responser in vitro med preparater inneholdende 8-substituerte guaninderivater
AR226212A1 (es)	1982-06-15	Procedimiento para preparar nuevos derivados de imidazo rifamicina
KR850002743A (ko)	1985-05-15	아미노산 유도체의 제조방법
ES255336Y (es)	1982-05-01	Incubadora para recien nacidos
FR2490632B1 (fr)	1986-12-12	Derives de l-argininal et procede de preparation
ES536138A0 (es)	1985-11-01	Procedimiento para preparar derivados azolicos
ES505898A0 (es)	1983-01-01	Procedimiento para preparar derivados de pirimidona
ES502276A0 (es)	1982-04-01	Procedimiento para preparar derivados de piridoxina
ES524106A0 (es)	1985-04-01	Procedimiento para preparar derivados de n-fenilpirazol
ES524830A0 (es)	1985-01-16	Procedimiento para preparar derivados de xantina
KR870001175A (ko)	1987-03-11	5-치환된-6-아미노피리미딘 유도체의 제조방법
MX6752E (es)	1986-06-25	Procedimiento para preparar derivados de carboestirilos
AR231447A1 (es)	1984-11-30	Procedimiento para preparar derivados de 4,5-dihidro-imidazo 1,2-a-quinazolin-2 1h-ona
ES500796A0 (es)	1982-01-01	Procedimiento para preparar derivados de pirimidona
ES527164A0 (es)	1985-05-01	Procedimiento para preparar derivados de 2-piperacinil-quinazolina
MX157614A (es)	1988-12-06	Procedimiento para preparar derivados de isohexido
ES521847A0 (es)	1984-08-01	Procedimiento para preparar derivados de pleuromutilina
ES502356A0 (es)	1982-04-01	Procedimiento para preparar colorantes bisazoicos
AR229509A1 (es)	1983-09-15	Procedimiento para preparar derivados de 2-halogeno-acetanilidas
ES503432A0 (es)	1982-11-01	Procedimiento para preparar derivados de genantreno
ES499421A0 (es)	1982-12-16	Procedimiento para preparar derivados de indano
DE3369992D1 (de)	1987-04-09	Pyrimidone derivatives
ES532142A0 (es)	1985-06-01	Procedimiento para preparar derivados acilaminofenolicos
AR227341A1 (es)	1982-10-15	Procedimiento para preparar derivados de bis-aminometil-antraquinona
GB1523031A (en)	1978-08-31	4-hydroxy - 5 - oxo - 1 - cyclopentene alkanoic acid derivatives methods for their preparation and their use