NO175873C - Mikrobiell fremgangsmåte for fremstilling av immunhemmende antibiotika - Google Patents

Mikrobiell fremgangsmåte for fremstilling av immunhemmende antibiotika

Info

Publication number
NO175873C
NO175873C NO895160A NO895160A NO175873C NO 175873 C NO175873 C NO 175873C NO 895160 A NO895160 A NO 895160A NO 895160 A NO895160 A NO 895160A NO 175873 C NO175873 C NO 175873C
Authority
NO
Norway
Prior art keywords
preparation
microbial process
immunosuppressive
antibiotics
immunosuppressive antibiotics
Prior art date
Application number
NO895160A
Other languages
English (en)
Norwegian (no)
Other versions
NO895160D0 (no
NO175873B (fr
NO895160L (no
Inventor
Antonia Jekkel Nee Bokany
Gabor Ambrus
Eva Toth Sarudy
Istvan Mihaly Szabo
Agota Huelber Nee Dobos
Attila Andor
Karoly Albrecht
Kalman Koenczoel
Valeria Szell
Eva Tomori Nee Joszt
Imre Moravcsik
Kalman Polya
Janos Erdei
Lajos Kiss
Karoly Nagy
Bela Palotas
Etelka Deli Nee Konszky
Karoly Buzasi
Aniko Molnar Nee Antal
Gyoergy Santha
Vilma Szaszhegyesi
Bela Makadi
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Publication of NO895160D0 publication Critical patent/NO895160D0/no
Publication of NO895160L publication Critical patent/NO895160L/no
Publication of NO175873B publication Critical patent/NO175873B/no
Publication of NO175873C publication Critical patent/NO175873C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO895160A 1988-12-20 1989-12-20 Mikrobiell fremgangsmåte for fremstilling av immunhemmende antibiotika NO175873C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU886497A HU201577B (en) 1988-12-20 1988-12-20 Process for producing cyclosporin antibiotics

Publications (4)

Publication Number Publication Date
NO895160D0 NO895160D0 (no) 1989-12-20
NO895160L NO895160L (no) 1990-06-21
NO175873B NO175873B (fr) 1994-09-12
NO175873C true NO175873C (no) 1994-12-21

Family

ID=10971727

Family Applications (1)

Application Number Title Priority Date Filing Date
NO895160A NO175873C (no) 1988-12-20 1989-12-20 Mikrobiell fremgangsmåte for fremstilling av immunhemmende antibiotika

Country Status (23)

Country Link
US (1) US5156960A (fr)
EP (1) EP0379708B1 (fr)
JP (1) JPH0763356B2 (fr)
AT (1) AT393135B (fr)
BG (1) BG60274B2 (fr)
CA (1) CA2006144C (fr)
CZ (1) CZ283557B6 (fr)
DD (1) DD290356A5 (fr)
DE (1) DE58908740D1 (fr)
DK (1) DK174719B1 (fr)
FI (1) FI92603C (fr)
FR (1) FR2640641B1 (fr)
GB (1) GB2227489B (fr)
HU (1) HU201577B (fr)
IT (1) IT1237799B (fr)
LV (2) LV10102B (fr)
NO (1) NO175873C (fr)
PL (1) PL162959B1 (fr)
RU (1) RU1836425C (fr)
SE (1) SE505442C2 (fr)
SK (1) SK722589A3 (fr)
UA (1) UA13320A (fr)
YU (1) YU47100B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE158022T1 (de) * 1991-01-25 1997-09-15 Fujisawa Pharmaceutical Co Prozess zur produktion von cyclosporin-a und/oder c
ES2078374T3 (es) * 1991-04-06 1995-12-16 Dresden Arzneimittel Procedimiento para la produccion por fermentacion y aislamiento de ciclosporina a, y nuevas cepas formadoras de ciclosporina.
FI92334C (fi) * 1992-12-30 1994-10-25 Leiras Oy Menetelmä syklosporiinien tuottamiseksi ja menetelmässä käytettävä uusi Tolypocladium-kanta
SI9300303A (en) * 1993-06-08 1994-12-31 Krka Tovarna Zdravil Process for isolation of hypolipemic effective substance
KR100304324B1 (ko) * 1994-10-13 2001-11-22 김용규 사이클로스포린a의제조방법
KR100341355B1 (ko) * 1994-10-14 2002-10-25 주식회사종근당 사이클로스포린a의제조방법
KR0126610B1 (ko) * 1994-10-18 1997-12-29 김충환 고생산 세포융합변이균주에 의한 사이클로스포린 a의 제조방법
EP0725076B1 (fr) * 1995-02-01 2001-06-06 National Research Development Corporation of India Procédé de préparation de la cyclosporine A de l'espèce tolypocladium
US5854276A (en) * 1995-06-29 1998-12-29 Fujisawa Pharmaceutical Co., Ltd. Substance WF16616, process for production thereof, and use thereof
DE19611094C2 (de) 1996-03-21 1999-06-17 Dresden Arzneimittel Verfahren zur Reinigung von Cyclosporin A und/oder verwandten Cyclosporinen aus einem Cyclosporin-haltigen Rohextrakt unter Anwendung chromatographischer Verfahren mit Kieselgel als Adsorbens
US5709797A (en) * 1996-06-05 1998-01-20 Poli Industria Chimica S.P.A. Method of isolating cyclosporins
US5747330A (en) * 1996-06-05 1998-05-05 Poli Industria Chimica Antibiotic producing microbe
HU223054B1 (hu) * 1997-03-25 2004-03-01 BIOGAL Gyógyszergyár Rt. Tisztítási eljárás nagytisztaságú ciklosporin A előállítására
DK1154759T3 (da) 1998-12-30 2008-12-08 Dexcel Ltd Dispergerbart koncentrat til indgift af cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
DE60023189D1 (de) 2000-02-29 2006-02-23 Biocon Ltd Herstellung und reinigung von cyclosporin-a
DE60208180T2 (de) * 2001-04-20 2006-08-17 Debiopharm S.A. Modifiziertes, als medikamentvorstufe anwendbares cyclosporin und dessen verwendung
JP2006524232A (ja) 2003-03-17 2006-10-26 アルバニー モレキュラー リサーチ インコーポレーティッド 新規サイクロスポリン
EP1804823A4 (fr) 2004-09-29 2010-06-09 Amr Technology Inc Nouveaux analogues de la cyclosporine et leurs utilisations pharmaceutiques
JP2008514701A (ja) 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
US7361636B2 (en) 2004-10-06 2008-04-22 Amr Technology, Inc. Cyclosporin alkynes and their utility as pharmaceutical agents
US7696166B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
EP2151450A1 (fr) * 2008-07-29 2010-02-10 Sandoz AG Procédé de préparation d'oligopeptides cycliques microbiologiques
ES2661583T3 (es) * 2011-04-28 2018-04-02 Celgene Corporation Métodos y composiciones usando inhibidores de PDE4 para el tratamiento y gestión de enfermedades autoinmunes e inflamatorias
GB201319791D0 (en) * 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
CN117025407B (zh) * 2023-06-28 2024-06-18 中国人民解放军海军特色医学中心 一株弯颈霉属真菌及其在制备抗辐损伤药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
US4215199A (en) * 1978-06-05 1980-07-29 Sandoz Ltd. Antibiotic production
SE448386B (sv) * 1978-10-18 1987-02-16 Sandoz Ag Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem
US4764503A (en) * 1986-11-19 1988-08-16 Sandoz Ltd. Novel cyclosporins

Also Published As

Publication number Publication date
LV10102B (en) 1995-02-20
HU201577B (en) 1990-11-28
IT8922765A0 (it) 1989-12-20
GB2227489B (en) 1992-09-16
DD290356A5 (de) 1991-05-29
IT1237799B (it) 1993-08-31
SK279768B6 (sk) 1999-03-12
LV10500B (en) 1995-08-20
FR2640641B1 (fr) 1991-05-10
HUT52164A (en) 1990-06-28
YU241589A (en) 1991-02-28
CZ283557B6 (cs) 1998-05-13
YU47100B (sh) 1994-12-28
LV10500A (lv) 1995-02-20
BG60274B1 (bg) 1994-03-31
EP0379708B1 (fr) 1994-12-07
NO895160D0 (no) 1989-12-20
FI92603B (fi) 1994-08-31
LV10102A (lv) 1994-05-10
JPH02231071A (ja) 1990-09-13
NO175873B (fr) 1994-09-12
DE58908740D1 (de) 1995-01-19
SE505442C2 (sv) 1997-08-25
DK174719B1 (da) 2003-10-06
DK640989A (da) 1990-06-21
BG60274B2 (en) 1994-03-31
JPH0763356B2 (ja) 1995-07-12
SE8904262D0 (sv) 1989-12-19
CZ722589A3 (cs) 1998-01-14
AT393135B (de) 1991-08-26
DK640989D0 (da) 1989-12-18
CA2006144C (fr) 1995-02-21
SK722589A3 (en) 1999-03-12
ATA289189A (de) 1991-01-15
UA13320A (uk) 1997-02-28
EP0379708A1 (fr) 1990-08-01
FR2640641A1 (fr) 1990-06-22
CA2006144A1 (fr) 1990-06-20
GB2227489A (en) 1990-08-01
FI896157A0 (fi) 1989-12-20
US5156960A (en) 1992-10-20
NO895160L (no) 1990-06-21
RU1836425C (ru) 1993-08-23
SE8904262L (sv) 1990-06-21
GB8928715D0 (en) 1990-02-28
FI92603C (fi) 1994-12-12
IT8922765A1 (it) 1991-06-20
PL162959B1 (en) 1994-01-31

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Legal Events

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MK1K Patent expired