NO176052C - Analogifremgangsmåte for fremstilling av terapeutisk aktive nukleosidderivater - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive nukleosidderivater

Info

Publication number: NO176052C
Authority: NO; Norway
Prior art keywords: therapeutically active; nucleoside derivatives; analogous process; active nucleoside; preparing therapeutically
Prior art date: 1988-10-05

Application number

NO911322A

Other languages

English (en)

Norwegian (no)

Other versions

NO176052B (no

NO911322L (no

NO911322D0 (no

Inventor

Jo Klaveness

Kjell Undheim

Frode Rise

Jostein Hatlelid

Original Assignee

Nycomed As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-05

Filing date

1991-04-04

Publication date

1995-01-25

1991-04-04 Application filed by Nycomed As filed Critical Nycomed As

1991-04-04 Publication of NO911322D0 publication Critical patent/NO911322D0/no

1991-06-04 Publication of NO911322L publication Critical patent/NO911322L/no

1994-10-17 Publication of NO176052B publication Critical patent/NO176052B/no

1995-01-25 Publication of NO176052C publication Critical patent/NO176052C/no

Links

238000004519 manufacturing process Methods 0.000 title 1
150000003833 nucleoside derivatives Chemical class 0.000 title 1
125000005041 acyloxyalkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
KDCGOANMDULRCW-UHFFFAOYSA-N Purine Natural products N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 abstract 1
CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical group C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
150000001408 amides Chemical group 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
150000002148 esters Chemical group 0.000 abstract 1
125000000561 purinyl group Chemical group N1=C(N=C2N=CNC2=C1)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

NO911322A 1988-10-05 1991-04-04 Analogifremgangsmåte for fremstilling av terapeutisk aktive nukleosidderivater NO176052C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB888823320A GB8823320D0 (en)	1988-10-05	1988-10-05	Chemical compounds
PCT/EP1989/001181 WO1990004602A1 (en)	1988-10-05	1989-10-05	Nucleoside derivatives

Publications (4)

Publication Number	Publication Date
NO911322D0 NO911322D0 (no)	1991-04-04
NO911322L NO911322L (no)	1991-06-04
NO176052B NO176052B (no)	1994-10-17
NO176052C true NO176052C (no)	1995-01-25

Family

ID=10644727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO911322A NO176052C (no)	1988-10-05	1991-04-04	Analogifremgangsmåte for fremstilling av terapeutisk aktive nukleosidderivater

Country Status (14)

Country	Link
EP (2)	EP0437469A1 (de)
JP (1)	JPH04500968A (de)
AT (1)	ATE111104T1 (de)
AU (1)	AU617543B2 (de)
DE (1)	DE68918036T2 (de)
DK (1)	DK58791D0 (de)
ES (1)	ES2058481T3 (de)
FI (1)	FI92491C (de)
GB (1)	GB8823320D0 (de)
NO (1)	NO176052C (de)
NZ (1)	NZ230919A (de)
OA (1)	OA09642A (de)
WO (1)	WO1990004602A1 (de)
ZA (1)	ZA897594B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2841074A (en) *	1954-09-23	1958-07-01	Thorell & Persson Ab	Sausage grilling and vending machine
DK156450C (da) *	1986-08-29	1990-01-15	Autochef Aps	Apparat til successiv tilberedning og udlevering af foedevareportioner, navnlig moentbetjent burgerautomat med mikroboelgeovn
ATE108183T1 (de) *	1987-03-24	1994-07-15	Nycomed Imaging As	2',3'-dideoxyribofuranoxid-derivate.
GB8815241D0 (en) *	1988-06-27	1988-08-03	Wellcome Found	Antiviral combinations & compounds therefor
GB8823319D0 (en) *	1988-10-05	1988-11-09	Nycomed As	Chemical compounds
GB8904855D0 (en) *	1989-03-03	1989-04-12	Beecham Group Plc	Pharmaceutical treatment
KR910007655A (ko) *	1989-10-03	1991-05-30	엠. 피. 잭슨	치료용 뉴클레오시드
JPH05501404A (ja) *	1989-11-06	1993-03-18	ニユコメド・アクシエセルカペト	ヌクレオシド誘導体
JPH05505815A (ja) *	1990-04-04	1993-08-26	ニユコメド・イメージング・アクシエセルカペト	ヌクレオシド誘導体
DE4110977A1 (de) *	1991-04-05	1992-10-08	Bayer Ag	Substituierte 2',3'-didesoxy-5-trifluormethyluridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK167377B1 (da) *	1985-09-17	1993-10-25	Wellcome Found	3'-azidopyrimidinnucleosider eller farmaceutisk acceptable salte eller estere deraf til anvendelse ved behandling af eller profylakse for en human retrovirusinfektion
DE3705794A1 (de) *	1987-02-24	1988-09-01	Bayer Ag	Verfahren zur herstellung von 1-(3-azido-2,3-didesoxy-ss-d- erythropentofuranosyl)pyrimidinen sowie neue zwischenprodukte
ATE108183T1 (de) *	1987-03-24	1994-07-15	Nycomed Imaging As	2',3'-dideoxyribofuranoxid-derivate.
GB8712691D0 (en) *	1987-05-29	1987-07-01	Wellcome Found	Therapeutic nucleosides
ZA886890B (en) *	1987-10-09	1989-05-30	Hoffmann La Roche	Novel dideoxycytidine derivatives

1988
- 1988-10-05 GB GB888823320A patent/GB8823320D0/en active Pending
1989
- 1989-10-05 EP EP89911035A patent/EP0437469A1/de active Pending
- 1989-10-05 AU AU43338/89A patent/AU617543B2/en not_active Ceased
- 1989-10-05 ZA ZA897594A patent/ZA897594B/xx unknown
- 1989-10-05 DE DE68918036T patent/DE68918036T2/de not_active Expired - Fee Related
- 1989-10-05 WO PCT/EP1989/001181 patent/WO1990004602A1/en not_active Ceased
- 1989-10-05 NZ NZ230919A patent/NZ230919A/xx unknown
- 1989-10-05 ES ES89202508T patent/ES2058481T3/es not_active Expired - Lifetime
- 1989-10-05 AT AT89202508T patent/ATE111104T1/de not_active IP Right Cessation
- 1989-10-05 EP EP89202508A patent/EP0362967B1/de not_active Expired - Lifetime
- 1989-10-05 JP JP1510305A patent/JPH04500968A/ja active Pending
1991
- 1991-03-22 OA OA59978A patent/OA09642A/en unknown
- 1991-04-03 DK DK91587A patent/DK58791D0/da not_active Application Discontinuation
- 1991-04-04 FI FI911621A patent/FI92491C/fi not_active IP Right Cessation
- 1991-04-04 NO NO911322A patent/NO176052C/no unknown

Also Published As

Publication number	Publication date
DE68918036T2 (de)	1995-01-26
EP0362967A1 (de)	1990-04-11
DE68918036D1 (de)	1994-10-13
ZA897594B (en)	1990-07-25
EP0437469A1 (de)	1991-07-24
ES2058481T3 (es)	1994-11-01
OA09642A (en)	1993-04-30
FI92491C (fi)	1994-11-25
ATE111104T1 (de)	1994-09-15
FI92491B (fi)	1994-08-15
AU4333889A (en)	1990-05-14
DK58791A (da)	1991-04-03
AU617543B2 (en)	1991-11-28
NO176052B (no)	1994-10-17
NO911322L (no)	1991-06-04
JPH04500968A (ja)	1992-02-20
NZ230919A (en)	1991-10-25
FI911621A0 (fi)	1991-04-04
WO1990004602A1 (en)	1990-05-03
GB8823320D0 (en)	1988-11-09
NO911322D0 (no)	1991-04-04
EP0362967B1 (de)	1994-09-07
DK58791D0 (da)	1991-04-03

Publication	Publication Date	Title
WO1991015498A3 (en)	1992-06-11	Nucleoside derivatives
AU7810791A (en)	1991-08-22	Derivatives of (hydroxymethyl)cyclobutane
FI894397A0 (fi)	1989-09-18	Menetelmä terapeuttisesti aktiivisten nukleosidijohdannaisten estereiden ja amidien valmistamiseksi
NO179906C (no)	1997-01-08	Fremgangsmåte for fremstilling av hydroksymetyl(metylencyklopentyl) puriner og -pyrimidiner
AU3154993A (en)	1994-07-19	Process for preparing substituted 1,3-oxathiolanes with antiviral properties
FI911621A0 (fi)	1991-04-04	Menetelmä farmakologisesti aktiivisten nukleosidijohdannaisten valmistamiseksi
AU627631B2 (en)	1992-08-27	Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders
ES2037401T3 (es)	1993-06-16	Procedimiento para preparar derivados de nucleosidos.
HUT54153A (en)	1991-01-28	Process for producing purinyl- and pyrimidinyltetrahydrofuran derivatives and pharmaceutical compositions comprising same
FI904066A0 (fi)	1990-08-16	Nya foereningar.
CA2188306A1 (en)	1995-11-02	Process for the diastereoselective synthesis of nucleoside analogues
MX9604880A (es)	1998-01-31	Procedimiento para la sintesis diasteroselectiva de analogos de nucleosido.