NO177785C - Analogifremgangsmåter for fremstilling av terapeutisk aktive alkoksy-4(1H)-pyridonderivater - Google Patents

Analogifremgangsmåter for fremstilling av terapeutisk aktive alkoksy-4(1H)-pyridonderivater

Info

Publication number
NO177785C
NO177785C NO910444A NO910444A NO177785C NO 177785 C NO177785 C NO 177785C NO 910444 A NO910444 A NO 910444A NO 910444 A NO910444 A NO 910444A NO 177785 C NO177785 C NO 177785C
Authority
NO
Norway
Prior art keywords
therapeutically active
analogous methods
pyridone derivatives
preparing therapeutically
active alkoxy
Prior art date
Application number
NO910444A
Other languages
English (en)
Norwegian (no)
Other versions
NO177785B (no
NO910444D0 (no
NO910444L (no
Inventor
Julian Aranda
Johannes Hartenstein
Reinhard Reck
Christoph Schaechtele
Claus Rudolph
Hartmut Osswald
Guenter Weinheimer
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of NO910444D0 publication Critical patent/NO910444D0/no
Publication of NO910444L publication Critical patent/NO910444L/no
Publication of NO177785B publication Critical patent/NO177785B/no
Publication of NO177785C publication Critical patent/NO177785C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO910444A 1988-08-06 1991-02-05 Analogifremgangsmåter for fremstilling av terapeutisk aktive alkoksy-4(1H)-pyridonderivater NO177785C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3826846A DE3826846A1 (de) 1988-08-06 1988-08-06 Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
PCT/EP1989/000927 WO1990001477A1 (de) 1988-08-06 1989-08-04 Alkoxy-4(1h)-pyridon-derivative, verfahren zu deren herstellung und deren verwendung als arzneimittel

Publications (4)

Publication Number Publication Date
NO910444D0 NO910444D0 (no) 1991-02-05
NO910444L NO910444L (no) 1991-02-05
NO177785B NO177785B (no) 1995-08-14
NO177785C true NO177785C (no) 1995-11-22

Family

ID=6360419

Family Applications (1)

Application Number Title Priority Date Filing Date
NO910444A NO177785C (no) 1988-08-06 1991-02-05 Analogifremgangsmåter for fremstilling av terapeutisk aktive alkoksy-4(1H)-pyridonderivater

Country Status (18)

Country Link
US (2) US5185352A (ja)
EP (2) EP0427765B1 (ja)
JP (1) JP2878361B2 (ja)
KR (1) KR920006779B1 (ja)
CN (1) CN1040193A (ja)
AT (1) ATE188469T1 (ja)
AU (1) AU627766B2 (ja)
CA (1) CA1340608C (ja)
DD (1) DD284003A5 (ja)
DE (2) DE3826846A1 (ja)
DK (1) DK174097B1 (ja)
ES (1) ES2144391T3 (ja)
GR (1) GR3033072T3 (ja)
HU (1) HUT56545A (ja)
NO (1) NO177785C (ja)
PT (1) PT91351B (ja)
WO (1) WO1990001477A1 (ja)
ZA (1) ZA895969B (ja)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283404C (en) * 1986-07-01 1991-04-23 Shigeru Sanai Cephalosporin compounds, processes for their preparation and antibacterial agents
DE3826846A1 (de) * 1988-08-06 1990-02-08 Goedecke Ag Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
FR2687674B1 (fr) * 1992-02-07 1995-05-19 Roussel Uclaf Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5674883A (en) * 1992-02-07 1997-10-07 Roussel Uclaf Derivatives of pyridone, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them
DE4243321A1 (de) * 1992-12-21 1994-06-23 Goedecke Ag Aminosäurederivate von Heterocyclen als PKC-Inhibitoren
US6046219A (en) * 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5849587A (en) * 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
EP1137427A1 (en) * 1998-12-07 2001-10-04 Ecosmart Technologies Inc. Cancer treatment composition and method using natural plant essential oils with signal transduction modulators
US6750342B1 (en) 1999-05-19 2004-06-15 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
US6867217B1 (en) 1999-05-19 2005-03-15 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade
US6906068B1 (en) 1999-05-19 2005-06-14 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl 1,2,4 - triazinones useful as anticoagulants
US6653316B1 (en) 1999-05-19 2003-11-25 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
US7015230B1 (en) 1999-05-19 2006-03-21 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade
US6664255B1 (en) 1999-05-19 2003-12-16 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
US6716838B1 (en) 1999-05-19 2004-04-06 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents
US6660885B2 (en) 2000-03-13 2003-12-09 Pharmacia Corporation Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
WO2001077079A2 (en) * 2000-04-05 2001-10-18 Pharmacia Corporation Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the coagulation cascade
CA2405561A1 (en) 2000-04-05 2001-10-18 Pharmacia Corporation Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade
US7119094B1 (en) 2000-11-20 2006-10-10 Warner-Lambert Company Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade
US7015223B1 (en) 2000-11-20 2006-03-21 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade
JP2004517074A (ja) 2000-11-20 2004-06-10 ファルマシア・コーポレーション 凝血カスケードを選択的に阻害するのに有用な置換された多環アリールおよびヘテロアリールピリジン類
BR0213092A (pt) 2001-10-03 2004-10-19 Pharmacia Corp Compostos heterocìclicos de 6 elementos úteis para a inibição seletiva da cascata de coagulação
CA2462645A1 (en) 2001-10-03 2003-11-13 Pharmacia Corporation Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade
CA2681545C (en) 2007-03-28 2013-10-01 Apotex Technologies Inc. Fluorinated derivatives of deferiprone
PL2268282T3 (pl) 2008-04-25 2015-04-30 Apotex Tech Inc Płynny preparat deferypronu o przyjemnym smaku
JP5845172B2 (ja) * 2009-05-01 2016-01-20 アデア ファーマスーティカルズ，インコーポレイテッド 高および低用量薬物の組み合わせを含む口腔内崩壊錠組成物
ME01911B (me) 2009-07-03 2014-12-20 Apotex Tech Inc Fluorisani derivati 3-hidroksipiridin-4-ona
EP3287443B1 (en) * 2015-04-24 2021-10-27 Shionogi & Co., Ltd 6-membered heterocyclic derivative and pharmaceutical composition comprising same
JP6692113B2 (ja) * 2016-10-21 2020-05-13 塩野義製薬株式会社 ６員複素環誘導体を含有する医薬組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA554715A (en) * 1958-03-18 Boesch Roger Ethers and thioethers and processes for their preparation
US2965641A (en) * 1959-07-06 1960-12-20 Searle & Co Derivatives of 1-(2-aminoethyl)-5-alkoxy-4-pyridones
CA978958A (en) * 1971-10-04 1975-12-02 Haydn W.R. Williams Substituted pyranones and -pyridones and process of manufacture
JPS59110675A (ja) * 1982-12-16 1984-06-26 Ss Pharmaceut Co Ltd ピリジン誘導体及びその製造方法
JPS59110674A (ja) * 1982-12-16 1984-06-26 Ss Pharmaceut Co Ltd ピリジン誘導体及びその製造法
GB8308055D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
CA1283404C (en) * 1986-07-01 1991-04-23 Shigeru Sanai Cephalosporin compounds, processes for their preparation and antibacterial agents
DE3826846A1 (de) * 1988-08-06 1990-02-08 Goedecke Ag Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel

Also Published As

Publication number Publication date
ES2144391T3 (es) 2000-06-16
KR900701755A (ko) 1990-12-04
US5185352A (en) 1993-02-09
HUT56545A (en) 1991-09-30
EP0427765A1 (de) 1991-05-22
NO177785B (no) 1995-08-14
PT91351A (pt) 1990-03-08
AU4048989A (en) 1990-03-05
CN1040193A (zh) 1990-03-07
NO910444D0 (no) 1991-02-05
DE58909865D1 (de) 2000-02-10
NO910444L (no) 1991-02-05
ZA895969B (en) 1990-05-30
KR920006779B1 (ko) 1992-08-17
CA1340608C (en) 1999-06-22
DD284003A5 (de) 1990-10-31
ATE188469T1 (de) 2000-01-15
AU627766B2 (en) 1992-09-03
JPH04500958A (ja) 1992-02-20
DK11391A (da) 1991-01-23
JP2878361B2 (ja) 1999-04-05
EP0354495A1 (de) 1990-02-14
WO1990001477A1 (de) 1990-02-22
DK11391D0 (da) 1991-01-23
EP0427765B1 (de) 2000-01-05
DK174097B1 (da) 2002-06-10
PT91351B (pt) 1997-01-31
DE3826846A1 (de) 1990-02-08
HU894581D0 (en) 1991-07-29
GR3033072T3 (en) 2000-08-31
US5322844A (en) 1994-06-21

Similar Documents

Publication Publication Date Title
HU894581D0 (en) Alkoxy-4(1h)-pyridone derivatives, process for producing these compounds and pharmaceutical preparatives containing them as active substance
ATE224888T1 (de) Pyridylalken- und pyridylalkin-säureamide als cytostatika und immunosuppressive arzneimittel
HU902681D0 (en) Process for the preparation of maleinimide derivatives and pharmaceutical compositions containing them as active ingredient
RU95111308A (ru) Производные 2-амино-4-фенил-4-оксомасляной кислоты, способы получения, фармацевтическая композиция
DE3478810D1 (en) Benzazocinone and benzazoninone derivatives, process for their preparation, pharmaceutical preparations containing these compounds, and their therapeutical use
SE8000435L (sv) N-bensylimidazoler med selektivt inhiberande verkan pa tromboxansyntetasenzymet jemte farmaceutiska beredningar innehallande sadana n-bensylimidazoler och sett for deras framstellning
DK0539479T3 (da) Heterocykliske forbindelser
HUT51269A (en) Process for producing benzimidazole derivatives and pharmaceutical compositions comprising same
IL94278A0 (en) 2-saccharine derivatives,their preparation and pharmaceutical compositions containing them
EP0434057A3 (en) Indolocarbazole derivatives, processes for their preparation and their use
RU94046300A (ru) Химические соединения, способ их получения, фармкомпозиция, способ лечения, промежуточный продукт
ES462387A1 (es) Procedimiento para la obtencion de derivados de 1,4-dihidro-piridin-azucar.
MY103593A (en) Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
HU896587D0 (en) 2-amino-carbonic acid derivatives, and medical preparations containing them as active agents, and process for the production of the active agents and the preparation