NO178620C - Isatinoksimderivater, farmasöytiske preparater som omfatter forbindelsene, samt anvendelse av forbindelsene for fremstilling av medikamenter - Google Patents

Isatinoksimderivater, farmasöytiske preparater som omfatter forbindelsene, samt anvendelse av forbindelsene for fremstilling av medikamenter

Info

Publication number: NO178620C
Authority: NO; Norway
Prior art keywords: compounds; medicaments; manufacture; pharmaceutical compositions; oxime derivatives
Prior art date: 1991-07-09

Application number

NO922686A

Other languages

English (en)

Norwegian (no)

Other versions

NO178620B (no

NO922686D0 (no

NO922686L (no

Inventor

Frank Watjen

Joergen Drejer

Leif Helth Jensen

Original Assignee

Neurosearch As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-09

Filing date

1992-07-08

Publication date

1996-05-02

1992-07-08 Application filed by Neurosearch As filed Critical Neurosearch As

1992-07-08 Publication of NO922686D0 publication Critical patent/NO922686D0/no

1993-01-11 Publication of NO922686L publication Critical patent/NO922686L/no

1996-01-22 Publication of NO178620B publication Critical patent/NO178620B/no

1996-05-02 Publication of NO178620C publication Critical patent/NO178620C/no

Links

150000001875 compounds Chemical class 0.000 title abstract 3
NGXLTYPELAIUHE-UHFFFAOYSA-N 2-(hydroxyamino)indol-3-one Chemical class C1=CC=C2C(=O)C(NO)=NC2=C1 NGXLTYPELAIUHE-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000004122 cyclic group Chemical group 0.000 abstract 2
OZDAOHVKBFBBMZ-UHFFFAOYSA-N 2-aminopentanedioic acid;hydrate Chemical compound O.OC(=O)C(N)CCC(O)=O OZDAOHVKBFBBMZ-UHFFFAOYSA-N 0.000 abstract 1
WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
108010011562 aspartic acid receptor Proteins 0.000 abstract 1
235000013922 glutamic acid Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
Lubricants (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO922686A 1991-07-09 1992-07-08 Isatinoksimderivater, farmasöytiske preparater som omfatter forbindelsene, samt anvendelse av forbindelsene for fremstilling av medikamenter NO178620C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US72747991A	1991-07-09	1991-07-09

Publications (4)

Publication Number	Publication Date
NO922686D0 NO922686D0 (no)	1992-07-08
NO922686L NO922686L (no)	1993-01-11
NO178620B NO178620B (no)	1996-01-22
NO178620C true NO178620C (no)	1996-05-02

Family

ID=24922831

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO922686A NO178620C (no)	1991-07-09	1992-07-08	Isatinoksimderivater, farmasöytiske preparater som omfatter forbindelsene, samt anvendelse av forbindelsene for fremstilling av medikamenter

Country Status (13)

Country	Link
EP (1)	EP0522494B1 (ja)
JP (1)	JP3270524B2 (ja)
AT (1)	ATE143659T1 (ja)
AU (1)	AU655643B2 (ja)
CA (1)	CA2073281A1 (ja)
DE (1)	DE69214205T2 (ja)
DK (1)	DK0522494T3 (ja)
ES (1)	ES2094850T3 (ja)
FI (1)	FI102276B (ja)
GR (1)	GR3021814T3 (ja)
IE (1)	IE921730A1 (ja)
NO (1)	NO178620C (ja)
ZA (1)	ZA924118B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK81593D0 (da) *	1993-07-07	1993-07-07	Neurosearch As	Nye isatinoximderivater, deres fremstilling og anvendelse
AR016384A1 (es) *	1997-07-30	2001-07-04	Smithkline Beecham Corp	Inhibidores de caspasas, composiciones farmaceuticas que comprenden dichos inhibidores de caspasas y uso de los inhibidores de caspasas para prepararun medicamento util para el tratamiento de apoptosis y desordenes asociados con excesiva actividad de la convertosa il-1 beta.
WO2000071102A2 (en)	1999-05-19	2000-11-30	Neurosearch A/S	Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE69677B1 (en) *	1989-12-11	1996-10-02	Neurosearch As	Isatine derivatives their preparation and use
US5164404A (en) *	1991-03-15	1992-11-17	Neurosearch A/S	Hydrazone derivatives and their use

1992
- 1992-05-29 AU AU17268/92A patent/AU655643B2/en not_active Ceased
- 1992-06-05 ZA ZA924118A patent/ZA924118B/xx unknown
- 1992-06-30 FI FI923032A patent/FI102276B/fi active
- 1992-07-01 IE IE173092A patent/IE921730A1/en not_active Application Discontinuation
- 1992-07-07 EP EP92111478A patent/EP0522494B1/en not_active Expired - Lifetime
- 1992-07-07 DK DK92111478.1T patent/DK0522494T3/da active
- 1992-07-07 AT AT92111478T patent/ATE143659T1/de not_active IP Right Cessation
- 1992-07-07 CA CA002073281A patent/CA2073281A1/en not_active Abandoned
- 1992-07-07 DE DE69214205T patent/DE69214205T2/de not_active Expired - Lifetime
- 1992-07-07 ES ES92111478T patent/ES2094850T3/es not_active Expired - Lifetime
- 1992-07-07 JP JP17991692A patent/JP3270524B2/ja not_active Expired - Fee Related
- 1992-07-08 NO NO922686A patent/NO178620C/no unknown
1996
- 1996-11-28 GR GR960403205T patent/GR3021814T3/el unknown

Also Published As

Publication number	Publication date
JP3270524B2 (ja)	2002-04-02
ZA924118B (en)	1993-08-03
FI923032A0 (fi)	1992-06-30
ES2094850T3 (es)	1997-02-01
FI102276B1 (fi)	1998-11-13
EP0522494A1 (en)	1993-01-13
DE69214205D1 (de)	1996-11-07
AU655643B2 (en)	1995-01-05
FI923032L (fi)	1993-01-10
NO178620B (no)	1996-01-22
FI102276B (fi)	1998-11-13
AU1726892A (en)	1993-01-14
CA2073281A1 (en)	1993-01-10
DK0522494T3 (ja)	1997-03-03
NO922686D0 (no)	1992-07-08
DE69214205T2 (de)	1997-02-06
NO922686L (no)	1993-01-11
EP0522494B1 (en)	1996-10-02
JPH05201976A (ja)	1993-08-10
IE921730A1 (en)	1993-01-13
ATE143659T1 (de)	1996-10-15
GR3021814T3 (en)	1997-02-28

Publication	Publication Date	Title
NO306464B1 (no)	1999-11-08	Benzimidazolforbindelser, farmasöytiske preparater som omfatter slike forbindelser, samt anvendelse av forbindelsene for fremstilling av medikamenter
NO159017C (no)	1988-11-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1,2,3,4-tetrahydroisokinolin-3-karboksylsyre-derivater.
ATE143598T1 (de)	1996-10-15	Arzneimittellösung enhaltend derivate von fk506
NO913136L (no)	1992-02-14	Fremgangsmaate for fremstilling av et preparat for oeyedraaper
HUP0101112A2 (hu)	2002-05-29	Piperidinil-aminometil-trifluor-metil-ciklikus-éter típusú vegyületek substance P antagonistaként történő felhasználása és ezeket tartalmazó gyógyszerkészítmények
IL84917A0 (en)	1988-06-30	Quinolinone derivative,its preparation and pharmaceutical compositions containing it
NO932520D0 (no)	1993-07-09	Preparat for helbredelse av sykdommen sjoegren's syndrom
HU9400595D0 (en)	1994-05-30	Isatinoxime derivatives and pharmaceutical compositions containing them
DE69105786D1 (de)	1995-01-26	Harnstoffderivate, deren Herstellung sowie diese enthaltende pharmazeutische Zusammensetzungen.
DK526087D0 (da)	1987-10-07	Antikonvulsive aminosyrederivater
NO910904D0 (no)	1991-03-07	Fremgangsmaate for fremstilling av en substituert aminforbindelse.
NO173991C (no)	1994-03-02	Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2,5-ditiazocin-derivater
KR880007070A (ko)	1988-08-26	백내장 치료용 약학 조성물
NO922686D0 (no)	1992-07-08	Isatinoksimderivater, fremgangsmaate for fremstilling derav samt anvendelse derav
EP0802179A4 (en)	2000-04-05	DERIVATE SUBSTITUTED AMIDINONAPHTHYLESTER
DE68909025D1 (de)	1993-10-14	Mittel zur Verhinderung von Zahnbelagbildung.
NO20020475L (no)	2002-03-13	2-aminotetralinderivater for terapi av glaukom
ATE186912T1 (de)	1999-12-15	Carbamoylpyrrolidon-derivate zur behandlung von depressionen und cerebrovasculären störungen
ATE72433T1 (de)	1992-02-15	Aether und thioaether mit heilender wirkung, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
NO20013480L (no)	2001-07-13	Legemiddel for torr hud
DK165967C (da)	1993-07-26	Anvendelse af en 2-oxo-imidazolidinforbindelse til fremstilling af et farmaceutisk praeparat
ATE95697T1 (de)	1993-10-15	Uricosuretische zusammensetzung.
FI941850A0 (fi)	1994-04-21	Uusi yhdiste, joka on leustroduksiini H, sen valmistus ja terapeuttinen käyttö