ATE143659T1 - Neue isatineoxime derivate, ihre herstellung und verwendung - Google Patents

Neue isatineoxime derivate, ihre herstellung und verwendung

Info

Publication number: ATE143659T1
Authority: AT; Austria
Prior art keywords: isatineoxime; derivatives; preparation; new; cyclic
Prior art date: 1991-07-09

Application number

AT92111478T

Other languages

English (en)

Inventor

Frank Waetjen

Jorgen Drejer

Leif Helth Jensen

Original Assignee

Neurosearch As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-09

Filing date

1992-07-07

Publication date

1996-10-15

1992-07-07 Application filed by Neurosearch As filed Critical Neurosearch As

1996-10-15 Application granted granted Critical

1996-10-15 Publication of ATE143659T1 publication Critical patent/ATE143659T1/de

Links

NGXLTYPELAIUHE-UHFFFAOYSA-N 2-(hydroxyamino)indol-3-one Chemical class C1=CC=C2C(=O)C(NO)=NC2=C1 NGXLTYPELAIUHE-UHFFFAOYSA-N 0.000 title 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000004122 cyclic group Chemical group 0.000 abstract 2
OZDAOHVKBFBBMZ-UHFFFAOYSA-N 2-aminopentanedioic acid;hydrate Chemical compound O.OC(=O)C(N)CCC(O)=O OZDAOHVKBFBBMZ-UHFFFAOYSA-N 0.000 abstract 1
WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
108010011562 aspartic acid receptor Proteins 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
235000013922 glutamic acid Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
Lubricants (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT92111478T 1991-07-09 1992-07-07 Neue isatineoxime derivate, ihre herstellung und verwendung ATE143659T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US72747991A	1991-07-09	1991-07-09

Publications (1)

Publication Number	Publication Date
ATE143659T1 true ATE143659T1 (de)	1996-10-15

Family

ID=24922831

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92111478T ATE143659T1 (de)	1991-07-09	1992-07-07	Neue isatineoxime derivate, ihre herstellung und verwendung

Country Status (13)

Country	Link
EP (1)	EP0522494B1 (de)
JP (1)	JP3270524B2 (de)
AT (1)	ATE143659T1 (de)
AU (1)	AU655643B2 (de)
CA (1)	CA2073281A1 (de)
DE (1)	DE69214205T2 (de)
DK (1)	DK0522494T3 (de)
ES (1)	ES2094850T3 (de)
FI (1)	FI102276B (de)
GR (1)	GR3021814T3 (de)
IE (1)	IE921730A1 (de)
NO (1)	NO178620C (de)
ZA (1)	ZA924118B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK81593D0 (da) *	1993-07-07	1993-07-07	Neurosearch As	Nye isatinoximderivater, deres fremstilling og anvendelse
AR016384A1 (es) *	1997-07-30	2001-07-04	Smithkline Beecham Corp	Inhibidores de caspasas, composiciones farmaceuticas que comprenden dichos inhibidores de caspasas y uso de los inhibidores de caspasas para prepararun medicamento util para el tratamiento de apoptosis y desordenes asociados con excesiva actividad de la convertosa il-1 beta.
WO2000071102A2 (en)	1999-05-19	2000-11-30	Neurosearch A/S	Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE69677B1 (en) *	1989-12-11	1996-10-02	Neurosearch As	Isatine derivatives their preparation and use
US5164404A (en) *	1991-03-15	1992-11-17	Neurosearch A/S	Hydrazone derivatives and their use

1992
- 1992-05-29 AU AU17268/92A patent/AU655643B2/en not_active Ceased
- 1992-06-05 ZA ZA924118A patent/ZA924118B/xx unknown
- 1992-06-30 FI FI923032A patent/FI102276B/fi active
- 1992-07-01 IE IE173092A patent/IE921730A1/en not_active Application Discontinuation
- 1992-07-07 EP EP92111478A patent/EP0522494B1/de not_active Expired - Lifetime
- 1992-07-07 DK DK92111478.1T patent/DK0522494T3/da active
- 1992-07-07 AT AT92111478T patent/ATE143659T1/de not_active IP Right Cessation
- 1992-07-07 CA CA002073281A patent/CA2073281A1/en not_active Abandoned
- 1992-07-07 DE DE69214205T patent/DE69214205T2/de not_active Expired - Lifetime
- 1992-07-07 ES ES92111478T patent/ES2094850T3/es not_active Expired - Lifetime
- 1992-07-07 JP JP17991692A patent/JP3270524B2/ja not_active Expired - Fee Related
- 1992-07-08 NO NO922686A patent/NO178620C/no unknown
1996
- 1996-11-28 GR GR960403205T patent/GR3021814T3/el unknown

Also Published As

Publication number	Publication date
NO178620C (no)	1996-05-02
JP3270524B2 (ja)	2002-04-02
ZA924118B (en)	1993-08-03
FI923032A0 (fi)	1992-06-30
ES2094850T3 (es)	1997-02-01
FI102276B1 (fi)	1998-11-13
EP0522494A1 (de)	1993-01-13
DE69214205D1 (de)	1996-11-07
AU655643B2 (en)	1995-01-05
FI923032L (fi)	1993-01-10
NO178620B (no)	1996-01-22
FI102276B (fi)	1998-11-13
AU1726892A (en)	1993-01-14
CA2073281A1 (en)	1993-01-10
DK0522494T3 (de)	1997-03-03
NO922686D0 (no)	1992-07-08
DE69214205T2 (de)	1997-02-06
NO922686L (no)	1993-01-11
EP0522494B1 (de)	1996-10-02
JPH05201976A (ja)	1993-08-10
IE921730A1 (en)	1993-01-13
GR3021814T3 (en)	1997-02-28

Legal Events

Date	Code	Title	Description
1997-04-15	UEP	Publication of translation of european patent specification
2004-04-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
FI941378A0 (fi)	1994-03-24	Bentsimidatsoliyhdisteitä, niiden käyttö ja valmistus
NO941968L (no)	1994-05-26	Organiske salter av N,N'-diacetylcystin
DE69229461D1 (de)	1999-07-29	Isatinoximderivate, ihre Herstellung und Anwendung
RU94019425A (ru)	1995-09-27	Производные изатиноксима, способ их получения, фармацевтическая композиция и способ лечения
ATE79257T1 (de)	1992-08-15	Verwendung von tetrahydrobenz(c,d>indol-6carboxamiden zur herstellung von arzneimitteln zur behandlung von angstzustaenden.
ATE92489T1 (de)	1993-08-15	Imid-derivate, ihre herstellung und verwendung.
NO903148L (no)	1991-01-15	Hemoreguleringspeptider.
DE3673688D1 (de)	1990-10-04	Succinimide derivate, herstellung und anwendung.
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DE69214205D1 (de)	1996-11-07	Neue Isatineoxime Derivate, ihre Herstellung und Verwendung
ATE92315T1 (de)	1993-08-15	Aminosaeurederivate enthaltende antikonvulsive zusammensetzungen und verwendung dieser aminosaeurederivate.
ATE198750T1 (de)	2001-02-15	Isatinoxim-derivate, ihre herstellung und verwendung
ATE153340T1 (de)	1997-06-15	Cyathane derivate und diese enthaltende nervenwachstumsfaktor produktion stimulatoren und antimikrobielle mittel
DE69105865D1 (de)	1995-01-26	Biphenyl-5,5'-bis-Alkansäurederivate, deren Herstellung und Verwendung.
DE69414017D1 (de)	1998-11-26	Benzimidazolderivate, ihre Herstellung und Verwendung
EP0802179A4 (de)	2000-04-05	Derivate substituierter amidinonaphthylester
DE3884878D1 (de)	1993-11-18	Uricosuretische Zusammensetzung.
ATE108444T1 (de)	1994-07-15	3-isoxazolonderivate, ihre herstellung und ihre anwendung in der therapeutik.