NO20000934L - Adipocyttspesifikke proteinhomologer - Google Patents
Adipocyttspesifikke proteinhomologerInfo
- Publication number
- NO20000934L NO20000934L NO20000934A NO20000934A NO20000934L NO 20000934 L NO20000934 L NO 20000934L NO 20000934 A NO20000934 A NO 20000934A NO 20000934 A NO20000934 A NO 20000934A NO 20000934 L NO20000934 L NO 20000934L
- Authority
- NO
- Norway
- Prior art keywords
- adipocyte
- specific protein
- protein homologs
- zsig39
- polypeptides
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 210000001789 adipocyte Anatomy 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 238000006471 dimerization reaction Methods 0.000 abstract 1
- 238000006384 oligomerization reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Foreliggende oppfinnelse vedrører polynukleotid- og polypeptidmolekyler for zsig39, et nytt medlem av familien av proteiner som bærer et kollagenlign- ende domene og et kuleformet domene. Polypeptidene og polynukleotidene som koder for dem, er involvert i dimeris- ering eller oligomerisering, og kan anvendes ved undersøkelse derav. Fore- liggende oppfinnelse omfatter også antistoffer mot zsig39-polypeptidene.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5698397P | 1997-08-26 | 1997-08-26 | |
| PCT/US1998/017724 WO1999010492A1 (en) | 1997-08-26 | 1998-08-26 | Adipocyte-specific protein homologs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20000934D0 NO20000934D0 (no) | 2000-02-25 |
| NO20000934L true NO20000934L (no) | 2000-04-26 |
Family
ID=22007782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20000934A NO20000934L (no) | 1997-08-26 | 2000-02-25 | Adipocyttspesifikke proteinhomologer |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6197930B1 (no) |
| EP (1) | EP1009829B1 (no) |
| JP (1) | JP3492999B2 (no) |
| KR (1) | KR20010023325A (no) |
| CN (1) | CN1272884A (no) |
| AT (1) | ATE324443T1 (no) |
| AU (1) | AU744254B2 (no) |
| CA (1) | CA2301660A1 (no) |
| DE (1) | DE69834334T2 (no) |
| NO (1) | NO20000934L (no) |
| WO (1) | WO1999010492A1 (no) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6469158B1 (en) * | 1992-05-14 | 2002-10-22 | Ribozyme Pharmaceuticals, Incorporated | Synthesis, deprotection, analysis and purification of RNA and ribozymes |
| US6642360B2 (en) * | 1997-12-03 | 2003-11-04 | Genentech, Inc. | Secreted polypeptides that stimulate release of proteoglycans from cartilage |
| FR2767135B1 (fr) | 1997-08-06 | 2002-07-12 | Genset Sa | Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes |
| US20020165143A1 (en) * | 1997-12-03 | 2002-11-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| EP1056846A1 (en) * | 1998-02-23 | 2000-12-06 | Smithkline Beecham Plc | Cerebellin-2 related polypeptides and dna coding therefor |
| US6406884B1 (en) * | 1999-06-18 | 2002-06-18 | Millennium Pharmaceuticals, Inc. | Secreted proteins and uses thereof |
| ATE397064T1 (de) | 1998-11-04 | 2008-06-15 | Serono Genetics Inst Sa | Genomische und vollständige cdna sequenzen von menschlichem adipozyten spezifischem apm1 und biallelische marker davon |
| DE60041912D1 (de) | 1999-02-10 | 2009-05-14 | Serono Genetics Inst Sa | Polymorphe marker des lsr-gens |
| US6544946B1 (en) | 1999-02-19 | 2003-04-08 | Zymogenetics, Inc. | Inhibitors for use in hemostasis and immune function |
| AU772103B2 (en) | 1999-02-19 | 2004-04-08 | Zymogenetics Inc. | Inhibitors for use in hemostasis and immune function |
| US20050042719A1 (en) * | 1999-05-27 | 2005-02-24 | Zymogenetics, Inc. | Adipocyte complement related protein homolog zacrp5 |
| AU5159500A (en) * | 1999-05-27 | 2000-12-18 | Zymogenetics Inc. | Adipocyte complement related protein homolog zacrp7 |
| WO2001032868A1 (en) * | 1999-11-04 | 2001-05-10 | Genset | Apm1 biallelic markers and uses thereof |
| US6989367B2 (en) * | 2000-01-14 | 2006-01-24 | Genset S.A. | OBG3 globular head and uses thereof |
| US20020058617A1 (en) * | 2000-01-14 | 2002-05-16 | Joachim Fruebis | OBG3 globular head and uses thereof for decreasing body mass |
| US6579852B2 (en) * | 2000-01-14 | 2003-06-17 | Genset S.A. | OBG3 globular head and uses thereof for decreasing body mass |
| US7338787B2 (en) | 2000-01-14 | 2008-03-04 | Serono Genetics Institute S.A. | Nucleic acids encoding OBG3 globular head and uses thereof |
| US6566332B2 (en) * | 2000-01-14 | 2003-05-20 | Genset S.A. | OBG3 globular head and uses thereof for decreasing body mass |
| IL156864A0 (en) * | 2001-01-16 | 2004-02-08 | Genset Sa | Polynucleotides and polypeptides and their use in metabolic disorders |
| EP1422241A1 (en) | 2002-11-19 | 2004-05-26 | Alexander Steinkasserer | Use of soluble forms of CD83 and nucleic acids encoding them for the treatment or prevention of diseases |
| US9102726B2 (en) * | 2002-12-04 | 2015-08-11 | Argos Therapeutics, Inc. | Nucleic acid of recombination expression vector encoding soluble forms of CD83, host cells transformed/transfected therewith and pharmaceutical compositions containing same |
| US7169898B2 (en) | 2002-12-04 | 2007-01-30 | Alexander Steinkasserer | Soluble CD83 proteins and use thereof for the treatment or prevention of a disease or medical condition caused by dysfunction or undesired function of a cellular immune response involving T cells |
| WO2009142759A1 (en) * | 2008-05-23 | 2009-11-26 | Argos Therapeutics, Inc. | Novel soluble cd83 polypeptides, formulations and methods of use |
| CN102940875B (zh) * | 2012-10-31 | 2015-09-30 | 中国人民解放军军事医学科学院微生物流行病研究所 | Paa蛋白及由其制备的抗体与应用 |
| SG11201510316UA (en) | 2013-07-09 | 2016-01-28 | Annexon Inc | Anti-complement factor c1q antibodies and uses thereof |
| PL3215527T3 (pl) | 2014-11-05 | 2025-04-28 | Annexon, Inc. | Humanizowane przeciwciała przeciwko czynnikowi dopełniacza C1Q i ich zastosowanie |
| FI3380518T3 (fi) | 2015-11-24 | 2026-05-29 | Annexon Inc | Antikomplementtitekijä-C1Q:n Fab-fragmentteja ja niiden käyttöjä |
| CN110195070B (zh) * | 2019-05-31 | 2022-11-04 | 天津大学 | 大肠杆菌全局调控因子的突变基因crp及应用 |
| US12486322B2 (en) | 2021-12-13 | 2025-12-02 | Annexon, Inc. | Anti-complement factor C1q antibodies with single binding arms and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000037640A2 (en) | 1998-12-22 | 2000-06-29 | Genentech, Inc. | Compositions and methods for the treatment of tumor |
| US5869330A (en) * | 1995-06-05 | 1999-02-09 | Whitehead Institute For Biomedical Research | DNA encoding a novel serum protein produced exclusively in adipocytes |
| WO1999035170A2 (en) | 1998-01-05 | 1999-07-15 | Genentech, Inc. | Compositions and methods for the treatment of tumor |
| NZ522634A (en) | 1997-12-03 | 2004-02-27 | Genentech Inc | PRO243 encoding a polypeptide with homology to chordin and antibodies and vectors |
| US6406884B1 (en) | 1999-06-18 | 2002-06-18 | Millennium Pharmaceuticals, Inc. | Secreted proteins and uses thereof |
| CA2348157A1 (en) | 1998-12-01 | 2000-06-08 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| KR20010103046A (ko) | 1999-03-08 | 2001-11-17 | 제넨테크, 인크. | 면역 관련 질환 치료용 조성물 및 치료 방법 |
-
1998
- 1998-08-26 CA CA002301660A patent/CA2301660A1/en not_active Abandoned
- 1998-08-26 JP JP2000507800A patent/JP3492999B2/ja not_active Expired - Fee Related
- 1998-08-26 CN CN98809769A patent/CN1272884A/zh active Pending
- 1998-08-26 EP EP98942266A patent/EP1009829B1/en not_active Expired - Lifetime
- 1998-08-26 DE DE69834334T patent/DE69834334T2/de not_active Expired - Fee Related
- 1998-08-26 KR KR1020007001961A patent/KR20010023325A/ko not_active Ceased
- 1998-08-26 WO PCT/US1998/017724 patent/WO1999010492A1/en not_active Ceased
- 1998-08-26 AT AT98942266T patent/ATE324443T1/de not_active IP Right Cessation
- 1998-08-26 AU AU90362/98A patent/AU744254B2/en not_active Ceased
- 1998-08-26 US US09/140,804 patent/US6197930B1/en not_active Expired - Lifetime
-
2000
- 2000-02-25 NO NO20000934A patent/NO20000934L/no not_active Application Discontinuation
- 2000-10-10 US US09/686,838 patent/US6482612B1/en not_active Expired - Fee Related
-
2002
- 2002-07-16 US US10/197,293 patent/US20030171547A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6197930B1 (en) | 2001-03-06 |
| WO1999010492A1 (en) | 1999-03-04 |
| US20030171547A1 (en) | 2003-09-11 |
| EP1009829A1 (en) | 2000-06-21 |
| AU9036298A (en) | 1999-03-16 |
| US6482612B1 (en) | 2002-11-19 |
| CN1272884A (zh) | 2000-11-08 |
| KR20010023325A (ko) | 2001-03-26 |
| JP2001513998A (ja) | 2001-09-11 |
| CA2301660A1 (en) | 1999-03-04 |
| JP3492999B2 (ja) | 2004-02-03 |
| DE69834334T2 (de) | 2007-04-26 |
| NO20000934D0 (no) | 2000-02-25 |
| AU744254B2 (en) | 2002-02-21 |
| EP1009829B1 (en) | 2006-04-26 |
| DE69834334D1 (de) | 2006-06-01 |
| ATE324443T1 (de) | 2006-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |