NO20002164L - Kombinasjon av en aldose reduktase inhibitor og en glycogen fosforylase inhibitor - Google Patents
Kombinasjon av en aldose reduktase inhibitor og en glycogen fosforylase inhibitorInfo
- Publication number
- NO20002164L NO20002164L NO20002164A NO20002164A NO20002164L NO 20002164 L NO20002164 L NO 20002164L NO 20002164 A NO20002164 A NO 20002164A NO 20002164 A NO20002164 A NO 20002164A NO 20002164 L NO20002164 L NO 20002164L
- Authority
- NO
- Norway
- Prior art keywords
- inhibitor
- combination
- aldose reductase
- glycogen phosphorylase
- reductase inhibitor
- Prior art date
Links
- ROJNYKZWTOHRNU-UHFFFAOYSA-N 2-chloro-4,5-difluoro-n-[[2-methoxy-5-(methylcarbamoylamino)phenyl]carbamoyl]benzamide Chemical compound CNC(=O)NC1=CC=C(OC)C(NC(=O)NC(=O)C=2C(=CC(F)=C(F)C=2)Cl)=C1 ROJNYKZWTOHRNU-UHFFFAOYSA-N 0.000 title 1
- 229940118148 Aldose reductase inhibitor Drugs 0.000 title 1
- 239000003288 aldose reductase inhibitor Substances 0.000 title 1
- MNQZXJOMYWMBOU-UHFFFAOYSA-N glyceraldehyde Chemical compound OCC(O)C=O MNQZXJOMYWMBOU-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Superheterodyne Receivers (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Noise Elimination (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6636597P | 1997-11-21 | 1997-11-21 | |
| PCT/IB1998/001752 WO1999026659A1 (fr) | 1997-11-21 | 1998-11-02 | Combinaison d'un inhibiteur de reductase d'aldose et d'un inhibiteur de phosphorylase de glycogene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20002164D0 NO20002164D0 (no) | 2000-04-27 |
| NO20002164L true NO20002164L (no) | 2000-07-19 |
Family
ID=22069038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20002164A NO20002164L (no) | 1997-11-21 | 2000-04-27 | Kombinasjon av en aldose reduktase inhibitor og en glycogen fosforylase inhibitor |
Country Status (38)
| Country | Link |
|---|---|
| EP (1) | EP1032424B9 (fr) |
| JP (1) | JP2002504478A (fr) |
| KR (2) | KR20010032304A (fr) |
| CN (1) | CN1279617A (fr) |
| AP (1) | AP911A (fr) |
| AR (1) | AR016423A1 (fr) |
| AT (1) | ATE205403T1 (fr) |
| AU (1) | AU733304B2 (fr) |
| BG (1) | BG104435A (fr) |
| BR (1) | BR9814698A (fr) |
| CA (1) | CA2310069A1 (fr) |
| DE (1) | DE69801680T2 (fr) |
| DK (1) | DK1032424T3 (fr) |
| DZ (1) | DZ2656A1 (fr) |
| EA (1) | EA002365B1 (fr) |
| ES (1) | ES2161548T3 (fr) |
| GR (1) | GR3037071T3 (fr) |
| GT (1) | GT199800166A (fr) |
| HR (1) | HRP20000327A2 (fr) |
| HU (1) | HUP0100272A3 (fr) |
| ID (1) | ID24524A (fr) |
| IL (1) | IL135713A0 (fr) |
| IS (1) | IS5453A (fr) |
| MA (1) | MA26568A1 (fr) |
| NO (1) | NO20002164L (fr) |
| OA (1) | OA11379A (fr) |
| PA (1) | PA8462301A1 (fr) |
| PE (1) | PE135399A1 (fr) |
| PL (1) | PL340643A1 (fr) |
| PT (1) | PT1032424E (fr) |
| SK (1) | SK7222000A3 (fr) |
| TN (1) | TNSN98211A1 (fr) |
| TR (1) | TR200001451T2 (fr) |
| UA (1) | UA57811C2 (fr) |
| UY (1) | UY25258A1 (fr) |
| WO (1) | WO1999026659A1 (fr) |
| YU (1) | YU30700A (fr) |
| ZA (1) | ZA9810636B (fr) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002536410A (ja) * | 1999-02-12 | 2002-10-29 | ノボ ノルディスク アクティーゼルスカブ | 肥満の治療又は予防もしくは食欲の調節を目的とした薬学的組成物の製造におけるピロリジン誘導体の使用 |
| EP1741445B1 (fr) | 2000-01-21 | 2013-08-14 | Novartis AG | Combinaisons à base d'inhibiteurs de DPP-IV et d'antidiabetiques |
| CO5271699A1 (es) * | 2000-01-24 | 2003-04-30 | Pfizer Prod Inc | Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa |
| US6570013B2 (en) | 2000-02-16 | 2003-05-27 | Pfizer Inc | Salts of zopolrestat |
| US6395767B2 (en) | 2000-03-10 | 2002-05-28 | Bristol-Myers Squibb Company | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method |
| IL144507A0 (en) * | 2000-07-31 | 2002-05-23 | Pfizer Prod Inc | Use of glycogen phosphorylase inhibitors to inhibit tumor growth |
| WO2002098429A1 (fr) * | 2001-06-07 | 2002-12-12 | Pfizer Products Inc. | Formes salines du zopolrestat, a savoir ethanolamine, diethanolamine ou triethanolamine |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| US7057046B2 (en) | 2002-05-20 | 2006-06-06 | Bristol-Myers Squibb Company | Lactam glycogen phosphorylase inhibitors and method of use |
| CA2392486A1 (fr) | 2002-07-05 | 2002-12-08 | Duchesnay Inc. | Forme posologique pharmaceutique portant une inscription pour les femmes enceintes |
| US7098235B2 (en) | 2002-11-14 | 2006-08-29 | Bristol-Myers Squibb Co. | Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds |
| US7576121B2 (en) | 2003-11-12 | 2009-08-18 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US7767828B2 (en) | 2003-11-12 | 2010-08-03 | Phenomix Corporation | Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US7674913B2 (en) | 2003-11-12 | 2010-03-09 | Phenomix Corporation | Heterocyclic boronic acid compounds |
| US7317109B2 (en) | 2003-11-12 | 2008-01-08 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| WO2006017292A1 (fr) | 2004-07-12 | 2006-02-16 | Phenomix Corporation | Composes cyano contraints |
| WO2006055462A1 (fr) | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | Derives 2-amino-4- tetraline fonctionnalisee et inhibiteurs de la glycogene phosphorylase associes |
| US7365061B2 (en) | 2004-11-15 | 2008-04-29 | Bristol-Myers Squibb Company | 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
| WO2006055435A1 (fr) | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | Derives de 2-aminonaphtalene et inhibiteurs de la glycogene phosphorylase associes |
| WO2006053274A2 (fr) | 2004-11-15 | 2006-05-18 | Bristol-Myers Squibb Company | Derives de tetraline 2-amino-1-fonctionnalises et inhibiteurs correspondants de glycogene phosphorylase |
| EP2527337A1 (fr) | 2005-04-14 | 2012-11-28 | Bristol-Myers Squibb Company | Inhibiteurs de la 11-bêta hydroxystéroïde déshydrogénase de type I |
| US7825139B2 (en) | 2005-05-25 | 2010-11-02 | Forest Laboratories Holdings Limited (BM) | Compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| CA2622608C (fr) | 2005-09-14 | 2014-08-19 | Takeda Pharmaceutical Company Limited | Administration d'inhibiteurs de dipeptidyl peptidase |
| EP2046753A2 (fr) | 2006-07-06 | 2009-04-15 | Brystol-Myers Squibb Company | Inhibiteurs de type i de la 11-bêta hydroxystéroïde déshydrogénase pyridone/hydroxypyridine |
| US7727978B2 (en) | 2006-08-24 | 2010-06-01 | Bristol-Myers Squibb Company | Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| JP2010524953A (ja) | 2007-04-17 | 2010-07-22 | ブリストル−マイヤーズ スクイブ カンパニー | 縮合ヘテロ環１１−β−ヒドロキシステロイドデヒドロゲナーゼＩ型阻害剤 |
| PE20090213A1 (es) | 2007-05-04 | 2009-02-28 | Bristol Myers Squibb Co | Agonistas del receptor acoplado a la proteina g gpr119 [6,5]-biciclicos |
| WO2008137435A1 (fr) | 2007-05-04 | 2008-11-13 | Bristol-Myers Squibb Company | Agonistes [6,6] and [6,7]-bicycliques du récepteur gpr 119 couplé à la protéine g |
| EA018709B1 (ru) | 2007-07-17 | 2013-10-30 | Бристол-Маерс Сквибб Компани | Пиридоновые агонисты сопряженного с g-белком рецептора gpr119 |
| TW201006821A (en) | 2008-07-16 | 2010-02-16 | Bristol Myers Squibb Co | Pyridone and pyridazone analogues as GPR119 modulators |
| WO2011041293A1 (fr) | 2009-09-30 | 2011-04-07 | Takeda Pharmaceutical Company Limited | Dérivés pyrazolo [1, 5a] pyrimidines comme inhibiteurs de kinase 1 régulatrice de signal d'apoptose |
| SI2531501T1 (sl) | 2010-02-03 | 2014-04-30 | Takeda Pharmaceutical Company Limited | Inhibitorji kinaze-1, ki regulirajo signal apoptoze |
| MX2012011460A (es) | 2010-04-08 | 2012-11-23 | Squibb Bristol Myers Co | Analogos de pirimidinilpiperidiniloxipiridinona como moduladores de gpr119. |
| ES2559209T3 (es) | 2010-04-14 | 2016-02-11 | Bristol-Myers Squibb Company | Nuevos activadores de la glucocinasa y métodos de uso de los mismos |
| EA201270778A1 (ru) | 2010-05-06 | 2013-04-30 | Бристол-Майерс Сквибб Компани | Бициклические гетероарильные аналоги в качестве модуляторов рецептора gpr119 |
| WO2011140161A1 (fr) | 2010-05-06 | 2011-11-10 | Bristol-Myers Squibb Company | Analogues de benzofuranyle en tant que modulateurs de gpr119 |
| RU2013135224A (ru) | 2011-01-20 | 2015-03-10 | Бионевиа Фармасьютикалс Инк. | Композиции с модифицированным высвобождением эпалрестата или его производных и способы их использования |
| EP2850073B1 (fr) | 2012-05-16 | 2017-07-19 | Bristol-Myers Squibb Company | Analogues de pyrimidinylpipéridinyloxypyridone en tant que modulateurs de gpr119 |
| US9580422B2 (en) | 2013-10-22 | 2017-02-28 | Bristol-Myers Squibb Company | Isotopically labeled triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| WO2018017910A1 (fr) | 2016-07-22 | 2018-01-25 | Bristol-Myers Squibb Company | Activateurs de glucokinase et leurs procédés d'utilisation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4825448A (en) * | 1986-08-07 | 1989-04-25 | International Mobile Machines Corporation | Subscriber unit for wireless digital telephone system |
| DE3889326D1 (de) * | 1988-05-27 | 1994-06-01 | Itt Ind Gmbh Deutsche | Korrekturschaltung für ein digitales Quadratur-Signalpaar. |
| US5391551A (en) * | 1993-05-10 | 1995-02-21 | Pfizer Inc. | Method of lowering blood lipid levels |
| EP0832066B1 (fr) * | 1995-06-06 | 2001-09-12 | Pfizer Inc. | (indole-2-carbonyl-)-amides substitues en n et leurs derives, servant d'inhibiteurs de la glycogene phosphorylase |
| CA2342471C (fr) * | 1995-06-06 | 2002-10-29 | Judith L. Treadway | Intermediaires amines de carbonyle-methyle heterocycliques |
-
1998
- 1998-02-11 UA UA2000052869A patent/UA57811C2/uk unknown
- 1998-10-27 GT GT199800166A patent/GT199800166A/es unknown
- 1998-10-28 PA PA19988462301A patent/PA8462301A1/es unknown
- 1998-11-02 SK SK722-2000A patent/SK7222000A3/sk unknown
- 1998-11-02 BR BR9814698-0A patent/BR9814698A/pt not_active IP Right Cessation
- 1998-11-02 PT PT81300054T patent/PT1032424E/pt unknown
- 1998-11-02 AU AU95558/98A patent/AU733304B2/en not_active Ceased
- 1998-11-02 EP EP98949193A patent/EP1032424B9/fr not_active Expired - Lifetime
- 1998-11-02 CN CN98811329A patent/CN1279617A/zh active Pending
- 1998-11-02 ES ES98949193T patent/ES2161548T3/es not_active Expired - Lifetime
- 1998-11-02 DE DE69801680T patent/DE69801680T2/de not_active Expired - Fee Related
- 1998-11-02 JP JP2000521860A patent/JP2002504478A/ja active Pending
- 1998-11-02 EA EA200000433A patent/EA002365B1/ru not_active IP Right Cessation
- 1998-11-02 ID IDW20000958A patent/ID24524A/id unknown
- 1998-11-02 HU HU0100272A patent/HUP0100272A3/hu unknown
- 1998-11-02 AT AT98949193T patent/ATE205403T1/de not_active IP Right Cessation
- 1998-11-02 PL PL98340643A patent/PL340643A1/xx unknown
- 1998-11-02 KR KR1020007005514A patent/KR20010032304A/ko not_active Ceased
- 1998-11-02 TR TR2000/01451T patent/TR200001451T2/xx unknown
- 1998-11-02 YU YU30700A patent/YU30700A/sh unknown
- 1998-11-02 WO PCT/IB1998/001752 patent/WO1999026659A1/fr not_active Ceased
- 1998-11-02 HR HR20000327A patent/HRP20000327A2/hr not_active Application Discontinuation
- 1998-11-02 CA CA002310069A patent/CA2310069A1/fr not_active Abandoned
- 1998-11-02 IL IL13571398A patent/IL135713A0/xx unknown
- 1998-11-02 DK DK98949193T patent/DK1032424T3/da active
- 1998-11-16 PE PE1998001113A patent/PE135399A1/es not_active Application Discontinuation
- 1998-11-18 DZ DZ980266A patent/DZ2656A1/fr active
- 1998-11-18 TN TNTNSN98211A patent/TNSN98211A1/fr unknown
- 1998-11-19 AR ARP980105883A patent/AR016423A1/es not_active Application Discontinuation
- 1998-11-19 MA MA25356A patent/MA26568A1/fr unknown
- 1998-11-19 AP APAP/P/1998/001401A patent/AP911A/en active
- 1998-11-19 UY UY25258A patent/UY25258A1/es not_active Application Discontinuation
- 1998-11-20 ZA ZA9810636A patent/ZA9810636B/xx unknown
-
1999
- 1999-05-07 KR KR1020007013394A patent/KR100661214B1/ko not_active Expired - Fee Related
-
2000
- 2000-04-14 IS IS5453A patent/IS5453A/is unknown
- 2000-04-27 NO NO20002164A patent/NO20002164L/no not_active Application Discontinuation
- 2000-05-12 OA OA1200000137A patent/OA11379A/en unknown
- 2000-05-15 BG BG104435A patent/BG104435A/bg unknown
-
2001
- 2001-10-30 GR GR20010401943T patent/GR3037071T3/el not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |