NO20002944L - Process for Preparation of Isopropylmethyl- (2-) 3-n-Propolysphenoxy) Ethyl) Amine - Google Patents

Process for Preparation of Isopropylmethyl- (2-) 3-n-Propolysphenoxy) Ethyl) Amine

Info

Publication number
NO20002944L
NO20002944L NO20002944A NO20002944A NO20002944L NO 20002944 L NO20002944 L NO 20002944L NO 20002944 A NO20002944 A NO 20002944A NO 20002944 A NO20002944 A NO 20002944A NO 20002944 L NO20002944 L NO 20002944L
Authority
NO
Norway
Prior art keywords
isopropylmethyl
amine
ethyl
preparation
propolysphenoxy
Prior art date
Application number
NO20002944A
Other languages
Norwegian (no)
Other versions
NO20002944D0 (en
Inventor
Ulf Larsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20002944D0 publication Critical patent/NO20002944D0/en
Publication of NO20002944L publication Critical patent/NO20002944L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Ny fremgangsmåte for syntese av isopropylmetyl-[2-(3-n-propoksyfenoksy)etyl]amin. Oppfinnelsen angår også et nytt mellomprodukt og et eventuelt rensetrinn i den nye fremgangsmåten. Videre angår foreliggende oppfinnelse også fremstillingen av en farmasøytisk formulering inneholdende isopropylmetyl-[2-(3-n-propoksyfenoksy)- etyl]amin og anvendelse av det rensede isopropylmetyl-[2-(3-n-propoksyfenoksy)- etyljamin i medisin.New method of synthesis of isopropylmethyl- [2- (3-n-propoxyphenoxy) ethyl] amine. The invention also relates to a new intermediate product and a possible purification step in the new process. Furthermore, the present invention also relates to the preparation of a pharmaceutical formulation containing isopropylmethyl- [2- (3-n-propoxyphenoxy) -ethyl] amine and the use of the purified isopropylmethyl- [2- (3-n-propoxyphenoxy) -ethylamine in medicine.

NO20002944A 1997-12-22 2000-06-08 Process for Preparation of Isopropylmethyl- (2-) 3-n-Propolysphenoxy) Ethyl) Amine NO20002944L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704834A SE9704834D0 (en) 1997-12-22 1997-12-22 New process
PCT/SE1998/002315 WO1999032430A1 (en) 1997-12-22 1998-12-15 Process for the preparation of isopropyl-methyl-[2-(3-n-propoxyphenoxy)ethyl]amine

Publications (2)

Publication Number Publication Date
NO20002944D0 NO20002944D0 (en) 2000-06-08
NO20002944L true NO20002944L (en) 2000-06-08

Family

ID=20409537

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002944A NO20002944L (en) 1997-12-22 2000-06-08 Process for Preparation of Isopropylmethyl- (2-) 3-n-Propolysphenoxy) Ethyl) Amine

Country Status (21)

Country Link
EP (1) EP1045826A1 (en)
JP (1) JP2001526253A (en)
KR (1) KR20010024790A (en)
CN (1) CN1283177A (en)
AR (1) AR017198A1 (en)
AU (1) AU1989199A (en)
BR (1) BR9814377A (en)
CA (1) CA2314988A1 (en)
EE (1) EE200000369A (en)
HU (1) HUP0100616A2 (en)
ID (1) ID27591A (en)
IL (1) IL136825A0 (en)
IS (1) IS5523A (en)
NO (1) NO20002944L (en)
PL (1) PL341438A1 (en)
SE (1) SE9704834D0 (en)
SK (1) SK8052000A3 (en)
TR (1) TR200001976T2 (en)
TW (1) TW436474B (en)
WO (1) WO1999032430A1 (en)
ZA (1) ZA9811238B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103702964A (en) * 2011-05-26 2014-04-02 索尔维特殊聚合物意大利有限公司 Hydro-fluorocompounds
JP6247992B2 (en) * 2014-04-17 2017-12-13 株式会社ダイセル Method for producing halogen compound
JP6635999B2 (en) * 2017-10-13 2020-01-29 株式会社ダイセル Method for producing potassium salt, and potassium salt

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90704A (en) * 1989-06-21 1994-10-07 Makhteshim Chem Works Ltd Environmentally safe method of preparing n-n-propyl-n-2-(2, 4, 6-trichlorophenoxy)-ethyl amine
AR004691A1 (en) * 1995-10-27 1999-03-10 Astrazeneca Ab NEW DERIVATIVES OF [3-ALCOXI-PENOXI -) - ETIL] -DIALKYLAMINE, A PHARMACEUTICAL COMPOSITION THAT INCLUDES THEM, THEIR USE AS LOCAL ANESTHETICS AND A PROCEDURE FOR THEIR PREPARATION

Also Published As

Publication number Publication date
SE9704834D0 (en) 1997-12-22
CA2314988A1 (en) 1999-07-01
KR20010024790A (en) 2001-03-26
ID27591A (en) 2001-04-12
TR200001976T2 (en) 2000-11-21
ZA9811238B (en) 1999-06-22
EE200000369A (en) 2001-12-17
JP2001526253A (en) 2001-12-18
AR017198A1 (en) 2001-08-22
CN1283177A (en) 2001-02-07
NO20002944D0 (en) 2000-06-08
WO1999032430A1 (en) 1999-07-01
AU1989199A (en) 1999-07-12
HUP0100616A2 (en) 2002-05-29
IL136825A0 (en) 2001-06-14
IS5523A (en) 2000-06-07
BR9814377A (en) 2000-10-10
SK8052000A3 (en) 2001-02-12
PL341438A1 (en) 2001-04-09
TW436474B (en) 2001-05-28
EP1045826A1 (en) 2000-10-25

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application