TR200001976T2 - Method for the preparation of isopropyl-methyl [2- (3-n-propoxyphenoxy) ethyl] amine - Google Patents

Method for the preparation of isopropyl-methyl [2- (3-n-propoxyphenoxy) ethyl] amine

Info

Publication number
TR200001976T2
TR200001976T2 TR2000/01976T TR200001976T TR200001976T2 TR 200001976 T2 TR200001976 T2 TR 200001976T2 TR 2000/01976 T TR2000/01976 T TR 2000/01976T TR 200001976 T TR200001976 T TR 200001976T TR 200001976 T2 TR200001976 T2 TR 200001976T2
Authority
TR
Turkey
Prior art keywords
propoxyphenoxy
amine
ethyl
methyl
isopropyl
Prior art date
Application number
TR2000/01976T
Other languages
Turkish (tr)
Inventor
Larsson Ulf
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TR200001976T2 publication Critical patent/TR200001976T2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Bu bulus izopropil-metil[2-(3-n-propoksifenoksi)etil]amin'in sentezine yönelik yeni bir usul ile ilgilidir.Öte yandan bu bulus ayni zamanda yeni usuldeki yeni bir ara ve duruma göre arindirmaya yönelik bir asama ile de ilgilidir. Buna ek olarak bu bulus izopropilmetil[2-(3-n-propoksifenoksi)etil]amin içeren ispençiyari bir formülün imalati ve arindirilmis izopropil-metil[2-(3-n-propoksifenoksi)etil]amin''in tipta kullanimi ile ilgilidir.This invention relates to a new method for the synthesis of isopropyl-methyl [2- (3-n-propoxyphenoxy) ethyl] amine. On the other hand, this invention also relates to a new intermediate in the new method and a step-by-step purification. In addition, this invention relates to the manufacture of a pharmaceutical formula containing isopropylmethyl [2- (3-n-propoxyphenoxy) ethyl] amine and the use of purified isopropyl-methyl [2- (3-n-propoxyphenoxy) ethyl] amine.

TR2000/01976T 1997-12-22 1998-12-15 Method for the preparation of isopropyl-methyl [2- (3-n-propoxyphenoxy) ethyl] amine TR200001976T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704834A SE9704834D0 (en) 1997-12-22 1997-12-22 New process

Publications (1)

Publication Number Publication Date
TR200001976T2 true TR200001976T2 (en) 2000-11-21

Family

ID=20409537

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01976T TR200001976T2 (en) 1997-12-22 1998-12-15 Method for the preparation of isopropyl-methyl [2- (3-n-propoxyphenoxy) ethyl] amine

Country Status (21)

Country Link
EP (1) EP1045826A1 (en)
JP (1) JP2001526253A (en)
KR (1) KR20010024790A (en)
CN (1) CN1283177A (en)
AR (1) AR017198A1 (en)
AU (1) AU1989199A (en)
BR (1) BR9814377A (en)
CA (1) CA2314988A1 (en)
EE (1) EE200000369A (en)
HU (1) HUP0100616A2 (en)
ID (1) ID27591A (en)
IL (1) IL136825A0 (en)
IS (1) IS5523A (en)
NO (1) NO20002944L (en)
PL (1) PL341438A1 (en)
SE (1) SE9704834D0 (en)
SK (1) SK8052000A3 (en)
TR (1) TR200001976T2 (en)
TW (1) TW436474B (en)
WO (1) WO1999032430A1 (en)
ZA (1) ZA9811238B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2714639A1 (en) * 2011-05-26 2014-04-09 Solvay Specialty Polymers Italy S.p.A. Hydro-fluorocompounds
JP6247992B2 (en) * 2014-04-17 2017-12-13 株式会社ダイセル Method for producing halogen compound
JP6635999B2 (en) * 2017-10-13 2020-01-29 株式会社ダイセル Method for producing potassium salt, and potassium salt

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90704A (en) * 1989-06-21 1994-10-07 Makhteshim Chem Works Ltd Environmentally safe method of preparing n-n-propyl-n-2-(2, 4, 6-trichlorophenoxy)-ethyl amine
AR004691A1 (en) * 1995-10-27 1999-03-10 Astrazeneca Ab NEW DERIVATIVES OF [3-ALCOXI-PENOXI -) - ETIL] -DIALKYLAMINE, A PHARMACEUTICAL COMPOSITION THAT INCLUDES THEM, THEIR USE AS LOCAL ANESTHETICS AND A PROCEDURE FOR THEIR PREPARATION

Also Published As

Publication number Publication date
HUP0100616A2 (en) 2002-05-29
AR017198A1 (en) 2001-08-22
SK8052000A3 (en) 2001-02-12
IS5523A (en) 2000-06-07
TW436474B (en) 2001-05-28
ID27591A (en) 2001-04-12
BR9814377A (en) 2000-10-10
JP2001526253A (en) 2001-12-18
CA2314988A1 (en) 1999-07-01
ZA9811238B (en) 1999-06-22
KR20010024790A (en) 2001-03-26
AU1989199A (en) 1999-07-12
SE9704834D0 (en) 1997-12-22
IL136825A0 (en) 2001-06-14
PL341438A1 (en) 2001-04-09
NO20002944D0 (en) 2000-06-08
NO20002944L (en) 2000-06-08
WO1999032430A1 (en) 1999-07-01
EP1045826A1 (en) 2000-10-25
CN1283177A (en) 2001-02-07
EE200000369A (en) 2001-12-17

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