NO20003166D0 - Benzoksazin-forbindelser for forandring av synaptisk respons - Google Patents
Benzoksazin-forbindelser for forandring av synaptisk responsInfo
- Publication number
- NO20003166D0 NO20003166D0 NO20003166A NO20003166A NO20003166D0 NO 20003166 D0 NO20003166 D0 NO 20003166D0 NO 20003166 A NO20003166 A NO 20003166A NO 20003166 A NO20003166 A NO 20003166A NO 20003166 D0 NO20003166 D0 NO 20003166D0
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- ampa receptors
- change
- disclosed
- methods
- Prior art date
Links
- 230000009782 synaptic response Effects 0.000 title abstract 2
- 150000005130 benzoxazines Chemical class 0.000 title 1
- 102000003678 AMPA Receptors Human genes 0.000 abstract 3
- 108090000078 AMPA Receptors Proteins 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000002708 enhancing effect Effects 0.000 abstract 2
- 230000001771 impaired effect Effects 0.000 abstract 2
- CMLFRMDBDNHMRA-UHFFFAOYSA-N 2h-1,2-benzoxazine Chemical group C1=CC=C2C=CNOC2=C1 CMLFRMDBDNHMRA-UHFFFAOYSA-N 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 230000036992 cognitive tasks Effects 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 230000002964 excitative effect Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 210000000225 synapse Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/998,300 US5985871A (en) | 1997-12-24 | 1997-12-24 | Benzoxazine compounds for enhancing synaptic response |
| PCT/US1998/027027 WO1999033469A1 (en) | 1997-12-24 | 1998-12-16 | Benzoxazine compounds for enhancing synaptic response |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20003166D0 true NO20003166D0 (no) | 2000-06-19 |
| NO20003166L NO20003166L (no) | 2000-08-07 |
| NO325764B1 NO325764B1 (no) | 2008-07-14 |
Family
ID=25545024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20003166A NO325764B1 (no) | 1997-12-24 | 2000-06-19 | Benzoksazin-forbindelser for forandring av synaptisk respons |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5985871A (no) |
| EP (1) | EP1054673B1 (no) |
| JP (1) | JP4620244B2 (no) |
| KR (1) | KR100561049B1 (no) |
| CN (1) | CN1160360C (no) |
| AT (1) | ATE261306T1 (no) |
| AU (1) | AU746971B2 (no) |
| BR (1) | BR9814478A (no) |
| CA (1) | CA2316356C (no) |
| DE (1) | DE69822344T2 (no) |
| DK (1) | DK1054673T3 (no) |
| ES (1) | ES2217615T3 (no) |
| HU (1) | HUP0102056A3 (no) |
| IL (1) | IL136783A (no) |
| MX (1) | MXPA00006155A (no) |
| NO (1) | NO325764B1 (no) |
| NZ (1) | NZ505212A (no) |
| PL (1) | PL194905B1 (no) |
| PT (1) | PT1054673E (no) |
| RU (1) | RU2246497C2 (no) |
| TR (1) | TR200001971T2 (no) |
| WO (1) | WO1999033469A1 (no) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6110935A (en) | 1997-02-13 | 2000-08-29 | The Regents Of The University Of California | Benzofurazan compounds for enhancing glutamatergic synaptic responses |
| US6124278A (en) * | 1998-04-03 | 2000-09-26 | The Regents Of The University Of California | Acylbenzoxazines for enhancing synaptic response |
| DE10004572A1 (de) * | 2000-02-02 | 2001-08-09 | Boehringer Ingelheim Pharma | Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| TWI232863B (en) | 2001-06-11 | 2005-05-21 | Akzo Nobel Nv | Benzoxazepine derivatives |
| KR100864267B1 (ko) | 2001-06-14 | 2008-10-20 | 엔.브이.오가논 | AMPA 수용체의 양성 조절제로서의(피리도/티에노)-[f]-옥사제핀-5-온 유도체 |
| KR20050094840A (ko) | 2003-01-13 | 2005-09-28 | 코텍스 파마슈티칼스, 인크. | 수면 부족 및 스트레스로 인한 인식 저하의 치료방법 |
| WO2006034196A1 (en) * | 2004-09-17 | 2006-03-30 | Lifelike Biomatic Inc. | Compositions for enhancing memory and methods therefor |
| GEP20125438B (en) * | 2007-01-03 | 2012-03-26 | Servier Lab | 3-substituted-[1,2,3]-benzotriazinone compound for enhancing glutamatergic synaptic responses |
| BRPI0720323A2 (pt) * | 2007-01-03 | 2016-08-09 | Cortex Pharma Inc | composto, método de tratamento, composição farmacêutica e uso do composto |
| WO2008143963A1 (en) | 2007-05-17 | 2008-11-27 | Cortex Pharmaceuticals, Inc. | Di-substituted amides for enhancing glutamatergic synaptic responses |
| US8119632B2 (en) | 2007-08-10 | 2012-02-21 | Cortex Pharmaceuticals, Inc. | Bicyclic amide derivatives for enhancing glutamatergic synaptic responses |
| CA2695742C (en) | 2007-08-10 | 2012-11-27 | Rudolf Mueller | Bicyclic amides for enhancing glutamatergic synaptic responses |
| WO2010054336A2 (en) * | 2008-11-10 | 2010-05-14 | The Regents Of The University Of California | Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction |
| US20130058915A1 (en) | 2010-03-02 | 2013-03-07 | Children's Medica Center Corporation | Methods and compositions for treatment of angelman syndrome and autism spectrum disorders |
| EP2801377B1 (en) | 2011-03-04 | 2019-08-07 | The Regents of The University of California | Hydrogel comprising cells for local release of growth factors to mediate motor recovery after stroke |
| KR101658274B1 (ko) * | 2011-04-06 | 2016-09-22 | 다이호야쿠힌고교 가부시키가이샤 | 신규 이미다조 옥사진 화합물 또는 그의 염 |
| EP3008167A4 (en) | 2013-06-13 | 2017-06-07 | VeroScience LLC | Compositions and methods for treating metabolic disorders |
| EP3436021A4 (en) | 2016-03-29 | 2019-11-06 | RespireRx Pharmaceuticals Inc. | COMPOSITIONS AND METHODS FOR TREATING ATTENTION DEFICIT DISORDER |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01207284A (ja) * | 1987-10-06 | 1989-08-21 | Takeda Chem Ind Ltd | アミド化合物 |
| EP0651746B1 (en) * | 1992-07-24 | 2002-03-27 | The Regents of the University of California | Drugs that enhance synaptic responses mediated by ampa receptors |
| JPH0943929A (ja) * | 1995-05-19 | 1997-02-14 | Matsushita Electric Ind Co Ltd | 電子写真複写装置 |
| US5650409A (en) * | 1995-06-02 | 1997-07-22 | Cortex Pharmaceuticals, Inc. | Benzoyl piperidines/pyrrolidines for enhancing synaptic response |
| US5736543A (en) * | 1996-04-03 | 1998-04-07 | The Regents Of The University Of California | Benzoxazines for enhancing synaptic response |
-
1997
- 1997-12-24 US US08/998,300 patent/US5985871A/en not_active Expired - Fee Related
-
1998
- 1998-12-16 KR KR1020007007128A patent/KR100561049B1/ko not_active Expired - Fee Related
- 1998-12-16 MX MXPA00006155A patent/MXPA00006155A/es not_active IP Right Cessation
- 1998-12-16 PT PT98964112T patent/PT1054673E/pt unknown
- 1998-12-16 DK DK98964112T patent/DK1054673T3/da active
- 1998-12-16 EP EP98964112A patent/EP1054673B1/en not_active Expired - Lifetime
- 1998-12-16 AU AU19305/99A patent/AU746971B2/en not_active Ceased
- 1998-12-16 CN CNB988125390A patent/CN1160360C/zh not_active Expired - Fee Related
- 1998-12-16 JP JP2000526226A patent/JP4620244B2/ja not_active Expired - Fee Related
- 1998-12-16 BR BR9814478-2A patent/BR9814478A/pt not_active Application Discontinuation
- 1998-12-16 TR TR2000/01971T patent/TR200001971T2/xx unknown
- 1998-12-16 RU RU2000119735/04A patent/RU2246497C2/ru not_active IP Right Cessation
- 1998-12-16 DE DE69822344T patent/DE69822344T2/de not_active Expired - Lifetime
- 1998-12-16 CA CA002316356A patent/CA2316356C/en not_active Expired - Fee Related
- 1998-12-16 AT AT98964112T patent/ATE261306T1/de active
- 1998-12-16 ES ES98964112T patent/ES2217615T3/es not_active Expired - Lifetime
- 1998-12-16 HU HU0102056A patent/HUP0102056A3/hu unknown
- 1998-12-16 WO PCT/US1998/027027 patent/WO1999033469A1/en not_active Ceased
- 1998-12-16 PL PL341427A patent/PL194905B1/pl not_active IP Right Cessation
- 1998-12-16 IL IL13678398A patent/IL136783A/xx not_active IP Right Cessation
-
2000
- 2000-06-16 NZ NZ505212A patent/NZ505212A/xx unknown
- 2000-06-19 NO NO20003166A patent/NO325764B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1054673B1 (en) | 2004-03-10 |
| AU746971B2 (en) | 2002-05-09 |
| WO1999033469A1 (en) | 1999-07-08 |
| PL341427A1 (en) | 2001-04-09 |
| CA2316356C (en) | 2009-11-03 |
| CN1160360C (zh) | 2004-08-04 |
| HUP0102056A3 (en) | 2003-03-28 |
| ATE261306T1 (de) | 2004-03-15 |
| NZ505212A (en) | 2003-02-28 |
| EP1054673A1 (en) | 2000-11-29 |
| ES2217615T3 (es) | 2004-11-01 |
| RU2246497C2 (ru) | 2005-02-20 |
| PL194905B1 (pl) | 2007-07-31 |
| CN1283114A (zh) | 2001-02-07 |
| US5985871A (en) | 1999-11-16 |
| JP4620244B2 (ja) | 2011-01-26 |
| JP2001527045A (ja) | 2001-12-25 |
| MXPA00006155A (es) | 2002-04-24 |
| PT1054673E (pt) | 2004-08-31 |
| EP1054673A4 (en) | 2001-07-18 |
| DE69822344T2 (de) | 2005-02-17 |
| CA2316356A1 (en) | 1999-07-08 |
| IL136783A0 (en) | 2001-06-14 |
| NO20003166L (no) | 2000-08-07 |
| KR100561049B1 (ko) | 2006-03-16 |
| IL136783A (en) | 2005-11-20 |
| KR20010033615A (ko) | 2001-04-25 |
| HUP0102056A2 (hu) | 2001-11-28 |
| TR200001971T2 (tr) | 2001-01-22 |
| DE69822344D1 (de) | 2004-04-15 |
| AU1930599A (en) | 1999-07-19 |
| DK1054673T3 (da) | 2004-07-05 |
| BR9814478A (pt) | 2000-10-10 |
| NO325764B1 (no) | 2008-07-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE226206T1 (de) | Benzoxazine zur erhöhung der synaptischen reaktionen | |
| NO20003166D0 (no) | Benzoksazin-forbindelser for forandring av synaptisk respons | |
| CA2138533A1 (en) | Drugs that enhance synaptic responses mediated by ampa receptors | |
| PT839134E (pt) | Benzoilpiperidinas/pirrolidinas para melhoramento da resposta sinaptica | |
| ID22342A (id) | Senyawa benzofurazan yang meningkatakan kegiatan penerima ampa | |
| NO20004383D0 (no) | Acylbenzoksaziner til forbedring av synaptisk respons | |
| EA200400584A1 (ru) | Соединения карбонилбензоксазина для усиления глутаматергических синаптических ответов |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |