NO20003344L - Topiske øyepreparater inneholdende immunosuppressive midler - Google Patents
Topiske øyepreparater inneholdende immunosuppressive midlerInfo
- Publication number
- NO20003344L NO20003344L NO20003344A NO20003344A NO20003344L NO 20003344 L NO20003344 L NO 20003344L NO 20003344 A NO20003344 A NO 20003344A NO 20003344 A NO20003344 A NO 20003344A NO 20003344 L NO20003344 L NO 20003344L
- Authority
- NO
- Norway
- Prior art keywords
- weight
- hydroxy
- ethanediyl
- oxy
- poly
- Prior art date
Links
- 230000000699 topical effect Effects 0.000 title abstract 3
- 229960003444 immunosuppressant agent Drugs 0.000 title abstract 2
- 239000003018 immunosuppressive agent Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- -1 poly (oxy-1,2-ethanediyl) Polymers 0.000 abstract 4
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 abstract 2
- 239000012948 isocyanate Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 229960001334 corticosteroids Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 229920001515 polyalkylene glycol Polymers 0.000 abstract 1
- 229920002635 polyurethane Polymers 0.000 abstract 1
- 239000004814 polyurethane Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Det beskrives terapeutiske preparater for topisk oftalmisk påføring, inne- holdende fra 0,02 til 5,0 vekt% immunsuppressive midler tilhørende gruppen av monocykliske undekapeptider, makrolid-laktoner eller kortikosteroider, i en bærer omfattende opp til 10 vekt% polyalkylenglykol-polyuretan-kopolymerer. Nevnte kopolymerer består fortrinnsvis av poly(oksy-1,2-etandiyl)-a-hydro-o>- hydroksypolymerer med 1,1'-metylen-bis-(4-isocyanatcykloheksan) som har en gjennomsnittlig molekylvekt på fra 1000 til 3000 i en hydrofil bærer og fortrinnsvis av poly[oksy-(metyl-1,2-etandiyl)]-a-hydro-co-hydroksypolymerer med 1,1 '-metylen-bis- (4-isocyanatcykloheksan) som har en gjennomsnittlig molekylvekt på'fra 1600 til ¿ 18000 i en lipofil bærer. Nevnte terapeutiske midler kan dessuten inneholde hjelpestoffer som er vanlige i topiske administrasjonsformer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ19974237A CZ287497B6 (cs) | 1997-12-30 | 1997-12-30 | Topické oční přípravky s imunosupresivními látkami |
| PCT/CZ1998/000054 WO1999034830A1 (en) | 1997-12-30 | 1998-12-17 | Topical ophthalmic preparations containing immunosuppressive agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20003344D0 NO20003344D0 (no) | 2000-06-27 |
| NO20003344L true NO20003344L (no) | 2000-06-27 |
Family
ID=5467853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20003344A NO20003344L (no) | 1997-12-30 | 2000-06-27 | Topiske øyepreparater inneholdende immunosuppressive midler |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1058560A1 (no) |
| JP (1) | JP2002500200A (no) |
| AU (1) | AU1481399A (no) |
| BG (1) | BG104558A (no) |
| CA (1) | CA2317010A1 (no) |
| CZ (1) | CZ287497B6 (no) |
| HR (1) | HRP20000258A2 (no) |
| HU (1) | HUP0004173A2 (no) |
| NO (1) | NO20003344L (no) |
| PL (1) | PL341604A1 (no) |
| SK (1) | SK284246B6 (no) |
| WO (1) | WO1999034830A1 (no) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000038703A1 (en) * | 1998-12-24 | 2000-07-06 | R-Tech Ueno, Ltd. | Agent for treating visual cell function disorder |
| US6864232B1 (en) | 1998-12-24 | 2005-03-08 | Sucampo Ag | Agent for treating visual cell function disorder |
| TWI324925B (en) * | 2001-08-23 | 2010-05-21 | Novartis Ag | Ophthalmic composition |
| SI1539157T1 (sl) * | 2002-09-18 | 2013-11-29 | Trustees Of The University Of Pennsylvania | Rapamicin za uporabo pri inhibiciji ali preprečevanju horoidalne neovaskularizacije |
| US7354574B2 (en) | 2002-11-07 | 2008-04-08 | Advanced Ocular Systems Limited | Treatment of ocular disease |
| US7083802B2 (en) * | 2003-07-31 | 2006-08-01 | Advanced Ocular Systems Limited | Treatment of ocular disease |
| JP2007505932A (ja) | 2003-09-18 | 2007-03-15 | マクサイト, インコーポレイテッド | 経強膜送達 |
| US7083803B2 (en) | 2003-09-19 | 2006-08-01 | Advanced Ocular Systems Limited | Ocular solutions |
| US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
| CA2597590A1 (en) | 2005-02-09 | 2006-08-17 | Macusight, Inc. | Formulations for ocular treatment |
| WO2007011880A2 (en) | 2005-07-18 | 2007-01-25 | Minu, L.L.C. | Enhanced ocular neuroprotection/neurostimulation |
| KR101478164B1 (ko) | 2006-02-09 | 2014-12-31 | 산텐 세이야꾸 가부시키가이샤 | 안정한 제제와 그 제조 및 사용 방법 |
| AU2007230964B2 (en) | 2006-03-23 | 2012-07-19 | Santen Pharmaceutical Co., Ltd. | Formulations and methods for vascular permeability-related diseases or conditions |
| US10172789B2 (en) | 2013-01-24 | 2019-01-08 | Palvella Therapeutics Llc | Compositions for transdermal delivery of mTOR inhibitors |
| HK1216146A1 (zh) * | 2013-03-27 | 2016-10-21 | Comprehensive Drug Enterprises, Ltd. | 眼药组合物、其制备方法及用途 |
| US11622929B2 (en) | 2016-03-08 | 2023-04-11 | Living Proof, Inc. | Long lasting cosmetic compositions |
| WO2018129364A1 (en) | 2017-01-06 | 2018-07-12 | Palvella Therapeutics Llc | Anhydrous compositions of mtor inhibitors and methods of use |
| US10987300B2 (en) | 2017-09-13 | 2021-04-27 | Living Proof, Inc. | Long lasting cosmetic compositions |
| US10842729B2 (en) | 2017-09-13 | 2020-11-24 | Living Proof, Inc. | Color protectant compositions |
| AU2018370210B2 (en) | 2017-11-20 | 2024-09-26 | Living Proof, Inc. | Properties for achieving long-lasting cosmetic performance |
| BR112020021902B1 (pt) | 2018-04-27 | 2024-02-20 | Living Proof, Inc | Composições cosméticas de poliuretano-ureia para tratamento capilar, método de preservação da ondulação no cabelo humano e os usos de poliuretano-ureia |
| EP3817743A4 (en) | 2018-07-02 | 2022-07-06 | Palvella Therapeutics, Inc. | ANHYDROUS COMPOSITIONS OF MTOR INHIBITORS AND METHODS OF USE |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5045317A (en) * | 1987-07-16 | 1991-09-03 | The Regents Of The University Of California | Enhancing the cutaneous penetration of pharmacologically active agents |
| US4971800A (en) * | 1988-07-08 | 1990-11-20 | The Regents Of The University Of California | Method and compositions for enhancing the cutaneous penetration of pharmacologically active agents |
| US5051260A (en) * | 1987-07-16 | 1991-09-24 | The Regents Of The University Of California | Method and composition for enhancing the cutaneous penetration of pharmacologically active agents |
-
1997
- 1997-12-30 CZ CZ19974237A patent/CZ287497B6/cs not_active IP Right Cessation
-
1998
- 1998-12-14 SK SK1717-98A patent/SK284246B6/sk not_active IP Right Cessation
- 1998-12-17 PL PL98341604A patent/PL341604A1/xx unknown
- 1998-12-17 JP JP2000527277A patent/JP2002500200A/ja not_active Withdrawn
- 1998-12-17 HU HU0004173A patent/HUP0004173A2/hu unknown
- 1998-12-17 WO PCT/CZ1998/000054 patent/WO1999034830A1/en not_active Ceased
- 1998-12-17 HR HR20000258A patent/HRP20000258A2/hr not_active Application Discontinuation
- 1998-12-17 AU AU14813/99A patent/AU1481399A/en not_active Abandoned
- 1998-12-17 CA CA002317010A patent/CA2317010A1/en not_active Abandoned
- 1998-12-17 EP EP98958793A patent/EP1058560A1/en not_active Withdrawn
-
2000
- 2000-06-27 NO NO20003344A patent/NO20003344L/no not_active Application Discontinuation
- 2000-06-27 BG BG104558A patent/BG104558A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20003344D0 (no) | 2000-06-27 |
| HRP20000258A2 (en) | 2001-04-30 |
| BG104558A (en) | 2001-02-28 |
| JP2002500200A (ja) | 2002-01-08 |
| WO1999034830A1 (en) | 1999-07-15 |
| AU1481399A (en) | 1999-07-26 |
| EP1058560A1 (en) | 2000-12-13 |
| SK284246B6 (sk) | 2004-12-01 |
| SK171798A3 (en) | 1999-10-08 |
| CZ423797A3 (cs) | 1999-07-14 |
| PL341604A1 (en) | 2001-04-23 |
| CZ287497B6 (cs) | 2000-12-13 |
| CA2317010A1 (en) | 1999-07-15 |
| HUP0004173A2 (hu) | 2001-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |