NO20003766L - PAI-2 og t-PA som diagnostiske markører for periodontal sykdom - Google Patents

PAI-2 og t-PA som diagnostiske markører for periodontal sykdom

Info

Publication number
NO20003766L
NO20003766L NO20003766A NO20003766A NO20003766L NO 20003766 L NO20003766 L NO 20003766L NO 20003766 A NO20003766 A NO 20003766A NO 20003766 A NO20003766 A NO 20003766A NO 20003766 L NO20003766 L NO 20003766L
Authority
NO
Norway
Prior art keywords
pai
periodontal disease
diagnostic markers
gcf
levels
Prior art date
Application number
NO20003766A
Other languages
English (en)
Other versions
NO20003766D0 (no
Inventor
Yin Xiao
Clive L Bunn
Peter M Bartold
Original Assignee
Biotech Australia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotech Australia Pty Ltd filed Critical Biotech Australia Pty Ltd
Publication of NO20003766D0 publication Critical patent/NO20003766D0/no
Publication of NO20003766L publication Critical patent/NO20003766L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8132—Plasminogen activator inhibitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
    • G01N2333/9726—Tissue plasminogen activator

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)

Abstract

Tilstedeværelse og omfang av periodontal sykdom kan diagnostiseres ved å måle nivåene av plasminogen- aktivatorinhibitor-2 (PAI-2) og/eller vevsplasminogenaktivator (t-PA) i gingival creviculærvæske (GCF). Nivåene av PAI-2 og t-PA i GCF øker kraftig i sammenheng med periodontal sykdom, og de korrelerer også med alvorligheten av sykdom på ulike steder hos den samme pasienten.
NO20003766A 1998-01-26 2000-07-21 PAI-2 og t-PA som diagnostiske markører for periodontal sykdom NO20003766L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7260198P 1998-01-26 1998-01-26
PCT/IB1999/000278 WO1999038010A1 (en) 1998-01-26 1999-01-26 PAI-2 AND t-PA AS DIAGNOSTIC MARKERS OF PERIODONTAL DISEASE

Publications (2)

Publication Number Publication Date
NO20003766D0 NO20003766D0 (no) 2000-07-21
NO20003766L true NO20003766L (no) 2000-09-25

Family

ID=22108666

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003766A NO20003766L (no) 1998-01-26 2000-07-21 PAI-2 og t-PA som diagnostiske markører for periodontal sykdom

Country Status (11)

Country Link
US (1) US6406873B2 (no)
EP (1) EP1051622A4 (no)
JP (1) JP2002501200A (no)
KR (1) KR20010034357A (no)
CN (1) CN1289409A (no)
AU (1) AU752143B2 (no)
CA (1) CA2318740A1 (no)
IL (1) IL137454A0 (no)
NO (1) NO20003766L (no)
NZ (1) NZ505332A (no)
WO (1) WO1999038010A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ380699A0 (en) * 1999-11-02 1999-11-25 Biotech Australia Pty Limited Protease inhibitors as modulators of periodontal wound healing
CN100340858C (zh) 2001-05-18 2007-10-03 维罗加茨公司 评估感染呼吸道细菌的受试者身体状态的试剂盒
SE0400191D0 (sv) 2004-01-30 2004-01-30 Tendera Ab A test kit for detecting periodontal disease
US20070003947A1 (en) * 2005-01-18 2007-01-04 Decarlo Arthur A Detecting genetic risk for periodontal disease
JP5702944B2 (ja) * 2010-03-31 2015-04-15 独立行政法人国立がん研究センター バイオマーカー
EP2896384B1 (en) * 2013-07-31 2023-11-29 Yoshio Motegi Method for producing periodontal index, production device therefor, production program therefor, recording medium recording same, method for diagnosing periodontitis, diagnosis device thereof, diagnosis program therefor, and recording medium recording same
CN106918706B (zh) * 2015-12-25 2019-05-21 广州瑞博奥生物科技有限公司 一种检测牙周病相关蛋白的抗体芯片试剂盒
RU2648765C1 (ru) * 2017-02-17 2018-03-28 федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) Способ качественного определения стоматологического статуса пациента с воспалением слизистой оболочки альвеолярного отростка челюсти по содержанию биомаркеров в ротовой жидкости

Also Published As

Publication number Publication date
AU2436399A (en) 1999-08-09
AU752143B2 (en) 2002-09-05
CA2318740A1 (en) 1999-07-29
CN1289409A (zh) 2001-03-28
US6406873B2 (en) 2002-06-18
NZ505332A (en) 2002-02-01
KR20010034357A (ko) 2001-04-25
EP1051622A4 (en) 2001-12-19
US20020012944A1 (en) 2002-01-31
EP1051622A1 (en) 2000-11-15
WO1999038010A1 (en) 1999-07-29
NO20003766D0 (no) 2000-07-21
JP2002501200A (ja) 2002-01-15
IL137454A0 (en) 2001-07-24

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application