NO20005357D0 - Sulfonamidholdige indolforbindelser - Google Patents

Sulfonamidholdige indolforbindelser

Info

Publication number: NO20005357D0
Authority: NO; Norway
Prior art keywords: hydrogen; ring; represents hydrogen; indole compounds; cyanophenyl
Prior art date: 1999-02-26

Application number

NO20005357A

Other languages

English (en)

Other versions

NO317299B1 (no

NO20005357L (no

Inventor

Toru Haneda

Akihiko Tsuruoka

Jun-Ichi Kamata

Tadashi Okabe

Keiko Takahashi

Kazumasa Nara

Shinichi Hamaoka

Norihiro Ueda

Takashi Owa

Toshiaki Wakabayashi

Yasuhiro Funahashi

Taro Semba

Naoko Hata

Yuji Yamamoto

Yoichi Ozawa

Naoko Tsukahara

Original Assignee

Eisai Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-26

Filing date

2000-10-24

Publication date

2000-10-24

2000-10-24 Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd

2000-10-24 Publication of NO20005357D0 publication Critical patent/NO20005357D0/no

2000-12-22 Publication of NO20005357L publication Critical patent/NO20005357L/no

2004-10-04 Publication of NO317299B1 publication Critical patent/NO317299B1/no

Links

150000002475 indoles Chemical class 0.000 title abstract 2
229940124530 sulfonamide Drugs 0.000 title 1
150000003456 sulfonamides Chemical class 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
-1 aminosulfonylphenyl group Chemical group 0.000 abstract 2
239000002246 antineoplastic agent Substances 0.000 abstract 2
125000004802 cyanophenyl group Chemical group 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
239000004037 angiogenesis inhibitor Substances 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
230000002035 prolonged effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20005357A 1999-02-26 2000-10-24 Sulfonamidholdige indolforbindelser, deres anvendelse samt farmasoytiske preparater inneholdende disse NO317299B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP11049870A JP2000247949A (ja)	1999-02-26	1999-02-26	スルホンアミド含有インドール化合物
PCT/JP2000/001071 WO2000050395A1 (en)	1999-02-26	2000-02-24	Sulfonamide-containing indole compounds

Publications (3)

Publication Number	Publication Date
NO20005357D0 true NO20005357D0 (no)	2000-10-24
NO20005357L NO20005357L (no)	2000-12-22
NO317299B1 NO317299B1 (no)	2004-10-04

Family

ID=12843091

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20005357A NO317299B1 (no)	1999-02-26	2000-10-24	Sulfonamidholdige indolforbindelser, deres anvendelse samt farmasoytiske preparater inneholdende disse

Country Status (17)

Country	Link
US (3)	US6469043B1 (no)
EP (1)	EP1074542B1 (no)
JP (3)	JP2000247949A (no)
KR (1)	KR100627611B1 (no)
CN (1)	CN1132814C (no)
AT (1)	ATE325094T1 (no)
AU (1)	AU766936B2 (no)
CA (1)	CA2327253C (no)
DE (1)	DE60027648T2 (no)
DK (1)	DK1074542T3 (no)
ES (1)	ES2259997T3 (no)
HU (1)	HU228787B1 (no)
NO (1)	NO317299B1 (no)
NZ (1)	NZ507464A (no)
PT (1)	PT1074542E (no)
RU (1)	RU2208607C2 (no)
WO (1)	WO2000050395A1 (no)

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DE60141889D1 (de) *	2000-02-03	2010-06-02	Eisai R&D Man Co Ltd	Inhibitoren der integrinexpression
CA2421254C (en) *	2000-08-30	2008-11-25	Primecyte, Inc.	Methods for treating tumors using sulfonyl compounds
TWI283575B (en) *	2000-10-31	2007-07-11	Eisai Co Ltd	Medicinal compositions for concomitant use as anticancer agent
KR20030080013A (ko) *	2001-02-21	2003-10-10	에자이 가부시키가이샤	인테그린 발현 억제를 통한 혈관 신생 억제제의 효과를검정하는 방법
CN1551766A (zh) *	2001-09-05	2004-12-01	��ʽ��	淋巴细胞活化抑制剂和自身免疫性疾病治疗剂
TWI325317B (en) *	2001-09-05	2010-06-01	Eisai R&D Man Co Ltd	Appetite-stimulating agents and remedies for anorexia
WO2003074045A1 (en) *	2002-03-05	2003-09-12	Eisai Co., Ltd.	Antitumor agent comprising combination of sulfonamide-containing heterocyclic compound with angiogenesis inhibitor
JP4390698B2 (ja) *	2002-06-05	2009-12-24	エフ．ホフマン−ラロシュアーゲー	Ｃｎｓ障害の処置のための５−ｈｔ６レセプターモジュレーターとしての１−スルホニル−４−アミノアルコキシインドール誘導体
JP4719671B2 (ja)	2003-03-28	2011-07-06	コーネル・リサーチ・ファンデーション・インコーポレイテッド	ミグラスタチンアナログ組成物およびその使用
WO2004091664A1 (ja) *	2003-04-18	2004-10-28	Eisai Co., Ltd.	細胞質リンゴ酸脱水素酵素阻害剤
JP4418430B2 (ja) *	2003-09-10	2010-02-17	エーザイ・アール・アンド・ディー・マネジメント株式会社	スルホンアミド含有インドール化合物の製造方法
MXPA06002732A (es) *	2003-09-10	2006-06-05	Eisai Co Ltd	Compuesto de indol que contiene sulfonamida cristalina y proceso para su preparacion.
WO2005048938A2 (en) *	2003-11-13	2005-06-02	California Pacific Medical Center	Anti-pecam therapy for metastasis suppression
US8957056B2 (en) *	2004-05-25	2015-02-17	Sloan-Kettering Instiute For Cancer Research	Migrastatin analogs in the treatment of cancer
WO2006030941A1 (ja)	2004-09-13	2006-03-23	Eisai R & D Management Co., Ltd.	スルホンアミド含有化合物の血管新生阻害物質との併用
US8772269B2 (en)	2004-09-13	2014-07-08	Eisai R&D Management Co., Ltd.	Use of sulfonamide-including compounds in combination with angiogenesis inhibitors
US8188141B2 (en) *	2004-09-23	2012-05-29	Sloan-Kettering Institute For Cancer Research	Isomigrastatin analogs in the treatment of cancer
PL1859793T3 (pl)	2005-02-28	2011-09-30	Eisai R&D Man Co Ltd	Nowe połączone zastosowanie związku sulfonamidowego w leczeniu choroby nowotworowej
US8957070B2 (en)	2005-04-20	2015-02-17	Takeda Pharmaceutical Company Limited	Glucokinase activator compounds, methods of activating glucokinase and methods of treating diabetes and obesity
AU2006285915B2 (en) *	2005-08-30	2011-02-24	Asahi Kasei Pharma Corporation	Sulfonamide compound
EP1956910B1 (en) *	2005-11-23	2014-09-17	The Board of Regents of The University of Texas System	Oncogenic ras-specific cytotoxic compound and methods of use thereof
US7625896B2 (en) *	2005-11-25	2009-12-01	Hoffman-La Roche Inc.	Pyridylsulfonamide derivatives
WO2007086605A1 (ja) *	2006-01-27	2007-08-02	Eisai R & D Management Co., Ltd.	スルホンアミド化合物の効果を予測する方法
EP2015070A4 (en)	2006-04-20	2010-04-21	Eisai R&D Man Co Ltd	Novel marker for sensitivity against sulfonamide compound
DE102007012284A1 (de) *	2007-03-16	2008-09-18	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
DE102007035334A1 (de)	2007-07-27	2009-01-29	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
DE102007035333A1 (de)	2007-07-27	2009-01-29	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
DE102007042154A1 (de)	2007-09-05	2009-03-12	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Arylsulfonylaminomethyphosphonsäure-Derivate, deren Herstellung und deren Verwendung als Arzneimittel
US20090142832A1 (en) *	2007-11-29	2009-06-04	James Dalton	Indoles, Derivatives, and Analogs Thereof and Uses Therefor
JP2012136435A (ja) *	2009-03-30	2012-07-19	Eisai R & D Management Co Ltd	腫瘍組織の感受性を検査する方法
AU2013222345B2 (en)	2012-02-22	2017-09-07	Sanford-Burnham Medical Research Institute	Sulfonamide compounds and uses as TNAP inhibitors
CN104098498A (zh) *	2014-07-30	2014-10-15	天津市斯芬克司药物研发有限公司	一种吲唑类化合物及其制备方法
WO2019102488A1 (en) *	2017-11-27	2019-05-31	Council Of Scientific & Industrial Research	Indole (sulfomyl) n-hydroxy benzamide derivatives as selective hdac inhibitors
AU2019211383A1 (en)	2018-01-25	2020-06-11	Dana-Farber Cancer Institute, Inc.	Sulfonamide derivatives for protein degradation
US20220162193A1 (en) *	2019-04-10	2022-05-26	Peloton Therapeutics, Inc.	Pyrazolesulfonamides as antitumor agents
US20240092770A1 (en) *	2022-08-15	2024-03-21	Recursion Pharmaceuticals, Inc.	Heterocycle RMB39 Modulators

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GB9115160D0 (en) *	1991-07-12	1991-08-28	Erba Carlo Spa	Methylen-oxindole derivatives and process for their preparation
US5169860A (en) *	1992-03-13	1992-12-08	Eli Lilly And Company	Antitumor compositions and methods of treatment
ZA941500B (en) *	1993-03-10	1995-09-04	Lilly Co Eli	Antitumor compositions and methods of treatment
JP3545461B2 (ja) *	1993-09-10	2004-07-21	エーザイ株式会社	二環式ヘテロ環含有スルホンアミド誘導体
RU2121997C1 (ru) *	1993-09-10	1998-11-20	Эйсай Ко., ЛТД	Производные 7-амино-1н-индола
JP3690831B2 (ja)	1995-02-27	2005-08-31	エーザイ株式会社	インドール含有スルホンアミド誘導体
JP4130700B2 (ja) *	1996-02-26	2008-08-06	エーザイ・アール・アンド・ディー・マネジメント株式会社	抗腫瘍剤含有組成物
JP3868534B2 (ja)	1996-05-24	2007-01-17	エーザイ・アール・アンド・ディー・マネジメント株式会社	スルホンアミド誘導体の製造法および中間体
DE60141889D1 (de) *	2000-02-03	2010-06-02	Eisai R&D Man Co Ltd	Inhibitoren der integrinexpression

1999
- 1999-02-26 JP JP11049870A patent/JP2000247949A/ja active Pending
2000
- 2000-02-24 US US09/647,215 patent/US6469043B1/en not_active Expired - Lifetime
- 2000-02-24 EP EP00905321A patent/EP1074542B1/en not_active Expired - Lifetime
- 2000-02-24 WO PCT/JP2000/001071 patent/WO2000050395A1/ja not_active Ceased
- 2000-02-24 KR KR1020007011026A patent/KR100627611B1/ko not_active Expired - Fee Related
- 2000-02-24 NZ NZ507464A patent/NZ507464A/en not_active IP Right Cessation
- 2000-02-24 DK DK00905321T patent/DK1074542T3/da active
- 2000-02-24 DE DE60027648T patent/DE60027648T2/de not_active Expired - Lifetime
- 2000-02-24 PT PT00905321T patent/PT1074542E/pt unknown
- 2000-02-24 JP JP2000600978A patent/JP3866041B2/ja not_active Expired - Fee Related
- 2000-02-24 CA CA002327253A patent/CA2327253C/en not_active Expired - Fee Related
- 2000-02-24 RU RU2000129508/04A patent/RU2208607C2/ru not_active IP Right Cessation
- 2000-02-24 AU AU26916/00A patent/AU766936B2/en not_active Ceased
- 2000-02-24 HU HU0101434A patent/HU228787B1/hu not_active IP Right Cessation
- 2000-02-24 AT AT00905321T patent/ATE325094T1/de active
- 2000-02-24 ES ES00905321T patent/ES2259997T3/es not_active Expired - Lifetime
- 2000-02-24 CN CN008002290A patent/CN1132814C/zh not_active Expired - Fee Related
- 2000-10-24 NO NO20005357A patent/NO317299B1/no not_active IP Right Cessation
2002
- 2002-03-18 US US10/098,421 patent/US6638964B2/en not_active Expired - Lifetime
- 2002-03-18 US US10/098,420 patent/US6673787B2/en not_active Expired - Lifetime
2010
- 2010-04-02 JP JP2010085696A patent/JP2010180229A/ja active Pending

Also Published As

Publication number	Publication date
CA2327253C (en)	2007-10-16
HU228787B1 (en)	2013-05-28
WO2000050395A1 (en)	2000-08-31
US6638964B2 (en)	2003-10-28
KR100627611B1 (ko)	2006-09-25
JP3866041B2 (ja)	2007-01-10
EP1074542A4 (en)	2002-02-06
ES2259997T3 (es)	2006-11-01
NZ507464A (en)	2003-10-31
US6469043B1 (en)	2002-10-22
NO317299B1 (no)	2004-10-04
EP1074542A1 (en)	2001-02-07
PT1074542E (pt)	2006-07-31
DK1074542T3 (da)	2006-08-14
NO20005357L (no)	2000-12-22
US20020128483A1 (en)	2002-09-12
RU2208607C2 (ru)	2003-07-20
CN1294579A (zh)	2001-05-09
US20020128480A1 (en)	2002-09-12
KR20010042434A (ko)	2001-05-25
JP2010180229A (ja)	2010-08-19
EP1074542B1 (en)	2006-05-03
ATE325094T1 (de)	2006-06-15
DE60027648D1 (de)	2006-06-08
DE60027648T2 (de)	2007-04-05
HUP0101434A3 (en)	2001-10-29
CN1132814C (zh)	2003-12-31
US6673787B2 (en)	2004-01-06
AU2691600A (en)	2000-09-14
AU766936B2 (en)	2003-10-23
HUP0101434A2 (hu)	2001-09-28
CA2327253A1 (en)	2000-08-31
JP2000247949A (ja)	2000-09-12

Legal Events

Date	Code	Title	Description
2004-11-22	ERR	Erratum	Free format text: SULFONAMIDHOLDIGE INDOLFORBINDELSER, DERES ANVENDELSE SAMT FARMASOYTISKE PREPARATER INNEHOLDENDE DISSE
2017-09-25	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
DK1074542T3 (da)	2006-08-14	Sulfonamidholdige indolforbindelser
NZ514873A (en)	2004-05-28	4,5,6,7-tetrahydroindazole derivatives as antitumor agents
ATE129714T1 (de)	1995-11-15	Heterocyclische biphosphonsäurederivate.
NZ336302A (en)	2000-08-25	Quinoline and quinazoline compounds useful in therapy, particularly in the treatment of benign prostatic hyperplasia
DK0749424T3 (da)	2001-11-26	Naphthalenderivater som prostaglandin-I2-agonister
EA200401056A1 (ru)	2005-04-28	Комбинация, содержащая производные тропана, полезные в терапии
DK0928788T3 (da)	2003-03-24	Imidazolidin-4-on-derivater, der er nyttige som anticancer-midler
DE60140456D1 (de)	2009-12-24	Aza heterocyclische derivate und ihre therapeutische verwendung
DE69609325D1 (de)	2000-08-17	Derivate des radicicols
DE69312243D1 (de)	1997-08-21	Phenoxy- oder Phenoxyalkyl-Piperidine als antivirale Mittel
CA2134077A1 (en)	1993-11-11	4-imidomethyl-1-[2'phenyl-2'oxoethyl-]piperidines as serotonin 5ht2-antagonists, their preparation and use in therapy
ATE233242T1 (de)	2003-03-15	Chinoline und chinazoline verbindungen und ihre therapeutische anwendung
NZ221699A (en)	1990-03-27	Pyridazinone derivatives; pharmaceutical compositions and intermediates
NO961797L (no)	1996-11-06	Anvendelse av benzopyranderivater for fremstilling av farmasöytiske sammensetninger beregnet for behandling av patologier forbundet med den Na+-uavhengige C1-HCO3-utbytter
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