NO20005820L - Pyrazolo[1,5-a]pyrimidin-derivater - Google Patents
Pyrazolo[1,5-a]pyrimidin-derivaterInfo
- Publication number
- NO20005820L NO20005820L NO20005820A NO20005820A NO20005820L NO 20005820 L NO20005820 L NO 20005820L NO 20005820 A NO20005820 A NO 20005820A NO 20005820 A NO20005820 A NO 20005820A NO 20005820 L NO20005820 L NO 20005820L
- Authority
- NO
- Norway
- Prior art keywords
- derivatives
- pyrazolo
- pyrimidine derivatives
- useful
- lower alkoxy
- Prior art date
Links
- LDIJKUBTLZTFRG-UHFFFAOYSA-N pyrazolo[1,5-a]pyrimidine Chemical class N1=CC=CN2N=CC=C21 LDIJKUBTLZTFRG-UHFFFAOYSA-N 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 102000003960 Ligases Human genes 0.000 abstract 1
- 108090000364 Ligases Proteins 0.000 abstract 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 206010040070 Septic Shock Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- MWUXSHHQAYIFBG-UHFFFAOYSA-N nitrogen oxide Inorganic materials O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 abstract 1
- 208000013223 septicemia Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13696098 | 1998-05-19 | ||
| PCT/JP1999/002572 WO1999059998A1 (en) | 1998-05-19 | 1999-05-17 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20005820D0 NO20005820D0 (no) | 2000-11-17 |
| NO20005820L true NO20005820L (no) | 2000-11-17 |
| NO317303B1 NO317303B1 (no) | 2004-10-04 |
Family
ID=15187527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005820A NO317303B1 (no) | 1998-05-19 | 2000-11-17 | Pyrazolo[1,5-a]pyrimidin-derivater |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6372749B1 (no) |
| EP (1) | EP1081149B1 (no) |
| JP (1) | JP4058587B2 (no) |
| KR (1) | KR100391398B1 (no) |
| CN (1) | CN1117093C (no) |
| AT (1) | ATE236166T1 (no) |
| AU (1) | AU751337B2 (no) |
| CA (1) | CA2331468C (no) |
| DE (1) | DE69906511T2 (no) |
| NO (1) | NO317303B1 (no) |
| WO (1) | WO1999059998A1 (no) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002226225B2 (en) * | 2001-01-18 | 2008-03-20 | Dermavant Sciences GmbH | Novel 1,2-diphenylethene derivatives for treatment of immune diseases |
| HUP0400891A2 (en) * | 2004-04-29 | 2006-04-28 | Janos Szolcsanyi | 7h-pyrrolo[2,3-d]pyrimidine derivatives, their pharmaceutically acceptable salts, pharmaceutical compositions containing them and process for the production of the compounds |
| US20150018566A1 (en) * | 2011-08-25 | 2015-01-15 | The Provost, Fellows, Foundation Scholars, & the Other Members of Board, of The College of the Holy | Tubulin binding agents |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2585462B2 (ja) | 1989-10-25 | 1997-02-26 | 株式会社大塚製薬工場 | ピラゾロ[1,5―a]ピリミジン誘導体 |
| JPH07309872A (ja) * | 1994-03-24 | 1995-11-28 | Otsuka Pharmaceut Factory Inc | 縮環ピリミジン誘導体及び鎮痛剤 |
| JP3252189B2 (ja) * | 1994-06-21 | 2002-01-28 | 株式会社大塚製薬工場 | ピラゾロ〔1,5−a〕ピリミジン誘導体 |
| JP3163412B2 (ja) * | 1994-06-21 | 2001-05-08 | 株式会社大塚製薬工場 | ピラゾロ〔1,5−a〕ピリミジン誘導体 |
| JP3163413B2 (ja) * | 1994-06-21 | 2001-05-08 | 株式会社大塚製薬工場 | 鎮痛剤 |
| KR100271998B1 (ko) * | 1995-04-10 | 2001-02-01 | 오쓰카 요시미쓰 | 피라졸로(1,5-a)피리미딘유도체 |
| JP3204877B2 (ja) | 1995-06-08 | 2001-09-04 | 株式会社エルモ社 | 資料提示装置 |
| US5843951A (en) * | 1995-09-28 | 1998-12-01 | Otsuka Pharmaceutical Factory Inc. | Analgesic composition of pyrazolo(1,5-A) pyrimidines |
| JPH10101671A (ja) | 1996-08-08 | 1998-04-21 | Otsuka Pharmaceut Factory Inc | 一酸化窒素合成酵素阻害剤 |
| JPH10114774A (ja) * | 1996-08-20 | 1998-05-06 | Otsuka Pharmaceut Factory Inc | 一酸化窒素合成酵素阻害剤 |
-
1999
- 1999-05-17 KR KR10-2000-7012981A patent/KR100391398B1/ko not_active Expired - Fee Related
- 1999-05-17 JP JP2000549616A patent/JP4058587B2/ja not_active Expired - Fee Related
- 1999-05-17 CA CA002331468A patent/CA2331468C/en not_active Expired - Fee Related
- 1999-05-17 EP EP99919634A patent/EP1081149B1/en not_active Expired - Lifetime
- 1999-05-17 AU AU37320/99A patent/AU751337B2/en not_active Ceased
- 1999-05-17 CN CN99805673A patent/CN1117093C/zh not_active Expired - Fee Related
- 1999-05-17 US US09/700,764 patent/US6372749B1/en not_active Expired - Fee Related
- 1999-05-17 WO PCT/JP1999/002572 patent/WO1999059998A1/ja not_active Ceased
- 1999-05-17 DE DE69906511T patent/DE69906511T2/de not_active Expired - Fee Related
- 1999-05-17 AT AT99919634T patent/ATE236166T1/de not_active IP Right Cessation
-
2000
- 2000-11-17 NO NO20005820A patent/NO317303B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20005820D0 (no) | 2000-11-17 |
| KR20010034871A (ko) | 2001-04-25 |
| KR100391398B1 (ko) | 2003-07-12 |
| DE69906511T2 (de) | 2004-01-29 |
| EP1081149A1 (en) | 2001-03-07 |
| DE69906511D1 (de) | 2003-05-08 |
| EP1081149A4 (en) | 2001-12-19 |
| US6372749B1 (en) | 2002-04-16 |
| JP4058587B2 (ja) | 2008-03-12 |
| AU3732099A (en) | 1999-12-06 |
| NO317303B1 (no) | 2004-10-04 |
| WO1999059998A1 (en) | 1999-11-25 |
| AU751337B2 (en) | 2002-08-15 |
| CA2331468A1 (en) | 1999-11-25 |
| EP1081149B1 (en) | 2003-04-02 |
| CA2331468C (en) | 2005-06-28 |
| CN1299362A (zh) | 2001-06-13 |
| ATE236166T1 (de) | 2003-04-15 |
| CN1117093C (zh) | 2003-08-06 |
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