NO20005841D0 - Pyrrolo[1,2-b]pyridazinderivater med sPLA2inhiberende effekt - Google Patents

Pyrrolo[1,2-b]pyridazinderivater med sPLA2inhiberende effekt

Info

Publication number
NO20005841D0
NO20005841D0 NO20005841A NO20005841A NO20005841D0 NO 20005841 D0 NO20005841 D0 NO 20005841D0 NO 20005841 A NO20005841 A NO 20005841A NO 20005841 A NO20005841 A NO 20005841A NO 20005841 D0 NO20005841 D0 NO 20005841D0
Authority
NO
Norway
Prior art keywords
pyrrolo
inhibitory effect
pyridazine derivatives
spla2
spla2 inhibitory
Prior art date
Application number
NO20005841A
Other languages
English (en)
Other versions
NO20005841L (no
Inventor
Mitsuaki Ohtani
Masahiro Fuji
Yoshikazu Fukui
Makoto Adachi
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of NO20005841D0 publication Critical patent/NO20005841D0/no
Publication of NO20005841L publication Critical patent/NO20005841L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20005841A 1998-05-21 2000-11-17 Pyrrolo[1,2-b]pyridazinderivater med sPLA2inhiberende effekt NO20005841L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13931998 1998-05-21
JP24473698 1998-08-31
PCT/JP1999/002630 WO1999059999A1 (en) 1998-05-21 1999-05-20 PYRROLO[1,2-b]PYRIDAZINE DERIVATIVES HAVING sPLA2 INHIBITORY EFFECT

Publications (2)

Publication Number Publication Date
NO20005841D0 true NO20005841D0 (no) 2000-11-17
NO20005841L NO20005841L (no) 2001-01-22

Family

ID=26472156

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005841A NO20005841L (no) 1998-05-21 2000-11-17 Pyrrolo[1,2-b]pyridazinderivater med sPLA2inhiberende effekt

Country Status (11)

Country Link
US (1) US6472389B1 (no)
EP (1) EP1085021A4 (no)
JP (1) JP4544446B2 (no)
KR (1) KR20010034881A (no)
CN (1) CN1302300A (no)
AU (1) AU748787B2 (no)
BR (1) BR9911048A (no)
CA (1) CA2332528A1 (no)
HU (1) HUP0103546A3 (no)
NO (1) NO20005841L (no)
WO (1) WO1999059999A1 (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2301586A1 (en) * 1997-08-28 1999-03-04 William Louis Macias Method for treatment of non-rheumatoid arthritis
ATE329619T1 (de) 1998-10-14 2006-07-15 Shionogi & Co Spla2-inhibitoren zur behandlung von ischämischen reperfusionsschäden
AU6015600A (en) 1999-07-19 2001-02-05 Shionogi & Co., Ltd. Tricyclic compounds having spla2-inhibitory activities
US6673781B1 (en) 1999-08-02 2004-01-06 Shionogi & Co., Ltd. Tricyclic compounds having sPLA2-inhibitory activities
US6787545B1 (en) 1999-08-23 2004-09-07 Shiongi & Co., Ltd. Pyrrolotriazine derivatives having spla2-inhibitory activities
WO2002000256A1 (fr) 2000-06-29 2002-01-03 Shionogi & Co., Ltd. Remedes contre la cirrhose
JPWO2002000621A1 (ja) * 2000-06-29 2004-04-22 塩野義製薬株式会社 Ｘ型ｓＰＬＡ２阻害作用を有する化合物
JP2004505982A (ja) * 2000-08-04 2004-02-26 イーライ・リリー・アンド・カンパニー 新規なｓＰＬＡ２インヒビター
TWI314457B (no) * 2001-03-19 2009-09-11 Shionogi & Co
US6730694B1 (en) 2001-07-20 2004-05-04 Eli Lilly And Company sPLA2 inhibitors
IL160810A0 (en) 2001-09-13 2004-08-31 Synta Pharmaceuticals Corp 1-glyoxlylamide indolizines for treating cancer
US6900208B2 (en) * 2002-03-28 2005-05-31 Bristol Myers Squibb Company Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
AR041470A1 (es) 2002-10-17 2005-05-18 Upjohn Co Compuestos de pirrolo (1,2 - b) piridazina y sus usos
NZ541232A (en) * 2003-01-09 2008-02-29 Astellas Pharma Inc Pyrrolopyridazine derivatives
CA2517034A1 (en) * 2003-03-13 2004-09-30 Synta Pharmaceuticals Corp. Fused pyrrole compounds
US7030112B2 (en) * 2003-03-25 2006-04-18 Bristol-Myers Squibb Company Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders
US7041671B2 (en) 2003-04-02 2006-05-09 Pfizer Inc Pyrrolo[1,2-b]pyridazine compounds and their uses
US7056920B2 (en) 2003-04-04 2006-06-06 Pfizer Inc Pyrrolo[1,2-B]pyridazine compounds and their uses
US7034023B2 (en) 2003-04-04 2006-04-25 Pfizer Inc Pyrrolo[1,2-B]pyridazine compounds and their uses
JP2006523675A (ja) * 2003-04-15 2006-10-19 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー ピロロ［１，２−ｂ］ピリダジン化合物及びそれらの使用
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
MXPA05011993A (es) * 2003-05-07 2006-02-02 Pharmacia & Upjohn Co Llc Compuestos de pirrolo[1,2-b]piridazina.
JP2007501801A (ja) * 2003-08-07 2007-02-01 日本たばこ産業株式会社 ピロロ［１，２−ｂ］ピリダジン誘導体
JP2007519605A (ja) * 2004-01-30 2007-07-19 日本たばこ産業株式会社 食欲抑制薬
WO2008133660A2 (en) * 2006-11-21 2008-11-06 Qd Vision, Inc. Nanocrystals including a group iiia element and a group va element, method, composition, device and other prodcucts
US8048880B2 (en) * 2007-05-03 2011-11-01 Anthera Pharmaceuticals, Inc. Treatment of cardiovascular disease and dyslipidemia using secretory phospholipase A2 (SPLA2) inhibitors and SPLA2 inhibitor combination therapies
CN102325449A (zh) * 2008-12-19 2012-01-18 安塞拉制药有限公司 用分泌磷脂酶A2(sPLA2)抑制剂或sPLA2抑制剂组合疗法处理主要不良心血管事件和急性冠状动脉综合症的方法
NZ720946A (en) 2009-04-29 2017-09-29 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
AR077428A1 (es) * 2009-07-29 2011-08-24 Sanofi Aventis (aza) indolizinacarboxamidas ciclicas su preparacion y su uso como agentes farmaceuticos
CN106986862A (zh) 2010-12-22 2017-07-28 Abbvie 公司 丙型肝炎抑制剂及其用途
WO2013028253A1 (en) 2011-08-19 2013-02-28 Qd Vision, Inc. Semiconductor nanocrystals and methods
CA3134613A1 (en) 2019-04-02 2020-10-08 Aligos Therapeutics, Inc. Compounds targeting prmt5

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018903A1 (en) * 1990-05-25 1991-12-12 Fujisawa Pharmaceutical Co., Ltd. Pyrrolopyridazine compounds
DE4224165A1 (de) * 1992-07-22 1994-01-27 Bayer Ag Imidazolinyl-pyrrolo-pyridazine
IL109309A (en) 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
IL109311A0 (en) 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
JP3109974B2 (ja) 1994-04-01 2000-11-20 イーライ・リリー・アンド・カンパニー １Ｈ−インドール−３−グリオキシルアミドｓＰＬＡ２阻害剤
BR9508298A (pt) * 1994-07-21 1998-11-03 Shionogi & Co Inibidores de indolizina de spla2
US6214876B1 (en) 1994-07-21 2001-04-10 Eli Lilly And Company Indene-1-acetamide sPLA2 inhibitors
US5641800A (en) 1994-07-21 1997-06-24 Eli Lilly And Company 1H-indole-1-functional sPLA2 inhibitors
US6160175A (en) 1995-12-13 2000-12-12 Eli Lilly And Company Naphthyl acetamides as sPLA2 inhibitors
WO1997021716A1 (en) 1995-12-13 1997-06-19 Eli Lilly And Company NAPHTHYL GLYOXAMIDES AS sPLA2 INHIBITORS
KR20000049210A (ko) 1996-10-30 2000-07-25 피터 지. 스트링거 치환된 트리시클릭류
US6353128B1 (en) 1996-12-03 2002-03-05 Eli Lilly And Company Phenyl acetamides as sPLA2 inhibitors
US5916922A (en) 1996-12-03 1999-06-29 Eli Lilly And Company Phenyl glyoxamides as SPLA2 inhibitors
ID18983A (id) 1996-12-04 1998-05-28 Lilly Co Eli Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia
US5919774A (en) 1996-12-10 1999-07-06 Eli Lilly And Company Pyrroles as sPLA2 inhibitors
TW455581B (en) 1997-06-26 2001-09-21 Lilly Co Eli Process for preparing 4-substituted-1H-indole-3-glyoxamides

Also Published As

Publication number Publication date
EP1085021A1 (en) 2001-03-21
EP1085021A4 (en) 2003-01-08
HUP0103546A3 (en) 2002-12-28
BR9911048A (pt) 2001-02-06
US6472389B1 (en) 2002-10-29
NO20005841L (no) 2001-01-22
AU3732799A (en) 1999-12-06
JP4544446B2 (ja) 2010-09-15
KR20010034881A (ko) 2001-04-25
CA2332528A1 (en) 1999-11-25
WO1999059999A1 (en) 1999-11-25
HUP0103546A2 (hu) 2002-02-28
CN1302300A (zh) 2001-07-04
AU748787B2 (en) 2002-06-13

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