NO20006023D0 - Celleadhesjonsinhibitor samt farmasöytiske sammensetninger inneholdende denne - Google Patents

Celleadhesjonsinhibitor samt farmasöytiske sammensetninger inneholdende denne

Info

Publication number: NO20006023D0
Authority: NO; Norway
Prior art keywords: pharmaceutical compositions; cell adhesion; well; compositions containing; adhesion inhibitor
Prior art date: 1998-05-28

Application number

NO20006023A

Other languages

English (en)

Other versions

NO20006023L (no

NO317990B1 (no

Inventor

Wen-Cherng Lee

Alan Gill

Original Assignee

Biogen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-28

Filing date

2000-11-28

Publication date

2000-11-28

2000-11-28 Application filed by Biogen Inc filed Critical Biogen Inc

2000-11-28 Publication of NO20006023D0 publication Critical patent/NO20006023D0/no

2001-01-17 Publication of NO20006023L publication Critical patent/NO20006023L/no

2005-01-17 Publication of NO317990B1 publication Critical patent/NO317990B1/no

Links

230000021164 cell adhesion Effects 0.000 title abstract 3
239000003112 inhibitor Substances 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
-1 2-methylphenylamino Chemical group 0.000 abstract 1
125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
229940000635 beta-alanine Drugs 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
230000007170 pathology Effects 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Diabetes (AREA)
Oncology (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20006023A 1998-05-28 2000-11-28 Celleadhesjonsinhibitor samt farmasoytiske sammensetninger inneholdende denne NO317990B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8706498P	1998-05-28	1998-05-28
PCT/US1999/011924 WO1999061421A1 (en)	1998-05-28	1999-05-28	A NOVEL VLA-4 INHIBITOR: oMePUPA-V

Publications (3)

Publication Number	Publication Date
NO20006023D0 true NO20006023D0 (no)	2000-11-28
NO20006023L NO20006023L (no)	2001-01-17
NO317990B1 NO317990B1 (no)	2005-01-17

Family

ID=22202907

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20006023A NO317990B1 (no)	1998-05-28	2000-11-28	Celleadhesjonsinhibitor samt farmasoytiske sammensetninger inneholdende denne

Country Status (30)

Country	Link
US (1)	US6495525B1 (no)
EP (1)	EP1082302B1 (no)
JP (1)	JP2002516309A (no)
KR (1)	KR100636713B1 (no)
CN (1)	CN1148350C (no)
AT (1)	ATE256659T1 (no)
AU (1)	AU764108B2 (no)
BG (1)	BG65021B1 (no)
CA (1)	CA2333656C (no)
CZ (1)	CZ298413B6 (no)
DE (1)	DE69913687T2 (no)
DK (1)	DK1082302T3 (no)
EA (1)	EA002988B1 (no)
EE (1)	EE04639B1 (no)
ES (1)	ES2211096T3 (no)
HU (1)	HUP0102255A3 (no)
IL (1)	IL139967A (no)
IS (1)	IS5737A (no)
MX (1)	MXPA00011774A (no)
NO (1)	NO317990B1 (no)
NZ (1)	NZ509199A (no)
PL (1)	PL198189B1 (no)
PT (1)	PT1082302E (no)
SI (1)	SI1082302T1 (no)
SK (1)	SK285280B6 (no)
TR (1)	TR200100190T2 (no)
UA (1)	UA65623C2 (no)
WO (1)	WO1999061421A1 (no)
YU (1)	YU75500A (no)
ZA (1)	ZA200007300B (no)

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AU751950B2 (en) *	1997-11-24	2002-09-05	Merck & Co., Inc.	Substituted beta-alanine derivatives as cell adhesion inhibitors
JP2002524529A (ja) *	1998-09-14	2002-08-06	ボードオブリージェンツ，ザユニバーシティオブテキサスシステム	インテグリンアンタゴニストを用いて多発性骨髄腫および骨髄腫誘導骨吸収を治療する方法
US7618630B2 (en)	1998-09-14	2009-11-17	Board Of Regents, The University Of Texas System	Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists
US6525069B1 (en)	1998-12-18	2003-02-25	Bristol-Myers Squibb Pharma Co.	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
CZ2002518A3 (cs)	1999-08-13	2002-05-15	Biogen, Inc.	Inhibitory buněčné adheze a farmaceutické prostředky, které je obsahují
YU41202A (sh)	1999-12-28	2005-03-15	Pfizer Products Inc.	Ne-peptidni inhibitori vezivanja za ćeliju zavisnog od vla-4 korisni pri tretiranju inflamatornih, autoimunih i respiratornih bolesti
JP4212358B2 (ja)	2000-12-28	2009-01-21	第一三共株式会社	Ｖｌａ−４阻害薬
CA2528586A1 (en)	2003-07-24	2005-02-03	Daiichi Pharmaceutical Co., Ltd.	Cyclohexanecarboxylic acid compound
US7419666B1 (en)	2004-02-23	2008-09-02	Massachusetts Eye And Ear Infirmary	Treatment of ocular disorders
US7196112B2 (en)	2004-07-16	2007-03-27	Biogen Idec Ma Inc.	Cell adhesion inhibitors
GT200500321A (es)	2004-11-09	2006-09-04		Compuestos y composiciones como inhibidores de proteina kinase.
US7685367B2 (en) *	2006-03-08	2010-03-23	Microsoft Corporation	Multi-cache cooperation for response output caching
US20100003224A1 (en) *	2006-08-02	2010-01-07	Genzyme Corporation	Combination Therapy
WO2008103378A2 (en)	2007-02-20	2008-08-28	Merrimack Pharmaceuticals, Inc.	Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist
MX2010011145A (es)	2008-04-11	2011-04-11	Merrimack Pharmaceuticals Inc	Enlazadores de la albumina de suero humana y conjugados de la misma.
WO2010059315A1 (en)	2008-11-18	2010-05-27	Merrimack Pharmaceuticals, Inc.	Human serum albumin linkers and conjugates thereof
HRP20171045T1 (hr)	2010-04-16	2017-10-06	Biogen Ma Inc.	Protutijela anti-vla-4
WO2014036520A1 (en)	2012-08-30	2014-03-06	Merrimack Pharmaceuticals, Inc.	Combination therapies comprising anti-erbb3 agents
CN119080931A (zh)	2018-06-04	2024-12-06	马萨诸塞州渤健公司	具有降低的效应功能的抗vla-4抗体
FI3873884T3 (fi)	2018-10-30	2025-02-24	Gilead Sciences Inc	3-(kinolin-8-yyli)-1,4-dihydropyrido[3,4-d]pyrimidiini-2,4-dionijohdannaisia alfa-4-beta-7-integriinin estäjinä tulehdussairauksien hoidossa
JP7189368B2 (ja)	2018-10-30	2022-12-13	ギリアードサイエンシーズ，インコーポレイテッド	アルファ４ベータ７インテグリンの阻害のための化合物
EP3873605B1 (en)	2018-10-30	2024-10-23	Gilead Sciences, Inc.	Compounds for inhibition of alpha4beta7 integrin
ES3013256T3 (en)	2018-10-30	2025-04-11	Gilead Sciences Inc	Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases
WO2021030438A1 (en)	2019-08-14	2021-02-18	Gilead Sciences, Inc.	Compounds for inhibition of alpha 4 beta 7 integrin

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DE4212304A1 (de)	1992-04-13	1993-10-14	Cassella Ag	Asparaginsäurederivate, ihre Herstellung und Verwendung
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1999
- 1999-05-28 NZ NZ509199A patent/NZ509199A/en unknown
- 1999-05-28 TR TR2001/00190T patent/TR200100190T2/xx unknown
- 1999-05-28 YU YU75500A patent/YU75500A/sh unknown
- 1999-05-28 PT PT99926019T patent/PT1082302E/pt unknown
- 1999-05-28 MX MXPA00011774A patent/MXPA00011774A/es not_active IP Right Cessation
- 1999-05-28 CN CNB998080020A patent/CN1148350C/zh not_active Expired - Fee Related
- 1999-05-28 SI SI9930526T patent/SI1082302T1/xx unknown
- 1999-05-28 EE EEP200000698A patent/EE04639B1/xx not_active IP Right Cessation
- 1999-05-28 AU AU42192/99A patent/AU764108B2/en not_active Ceased
- 1999-05-28 EA EA200001236A patent/EA002988B1/ru not_active IP Right Cessation
- 1999-05-28 CZ CZ20004425A patent/CZ298413B6/cs not_active IP Right Cessation
- 1999-05-28 UA UA2000127603A patent/UA65623C2/uk unknown
- 1999-05-28 AT AT99926019T patent/ATE256659T1/de not_active IP Right Cessation
- 1999-05-28 WO PCT/US1999/011924 patent/WO1999061421A1/en not_active Ceased
- 1999-05-28 DE DE69913687T patent/DE69913687T2/de not_active Expired - Fee Related
- 1999-05-28 ES ES99926019T patent/ES2211096T3/es not_active Expired - Lifetime
- 1999-05-28 JP JP2000550827A patent/JP2002516309A/ja active Pending
- 1999-05-28 DK DK99926019T patent/DK1082302T3/da active
- 1999-05-28 HU HU0102255A patent/HUP0102255A3/hu unknown
- 1999-05-28 KR KR1020007013421A patent/KR100636713B1/ko not_active Expired - Fee Related
- 1999-05-28 PL PL344440A patent/PL198189B1/pl not_active IP Right Cessation
- 1999-05-28 IL IL13996799A patent/IL139967A/xx not_active IP Right Cessation
- 1999-05-28 EP EP99926019A patent/EP1082302B1/en not_active Expired - Lifetime
- 1999-05-28 CA CA002333656A patent/CA2333656C/en not_active Expired - Fee Related
- 1999-05-28 SK SK1810-2000A patent/SK285280B6/sk not_active IP Right Cessation
2000
- 2000-11-28 IS IS5737A patent/IS5737A/is unknown
- 2000-11-28 NO NO20006023A patent/NO317990B1/no unknown
- 2000-11-28 US US09/724,107 patent/US6495525B1/en not_active Expired - Fee Related
- 2000-12-08 ZA ZA200007300A patent/ZA200007300B/en unknown
- 2000-12-18 BG BG105060A patent/BG65021B1/bg unknown

Also Published As

Publication number	Publication date
DK1082302T3 (da)	2004-04-26
MXPA00011774A (es)	2002-10-17
CZ298413B6 (cs)	2007-09-26
BG65021B1 (bg)	2006-12-29
PL198189B1 (pl)	2008-06-30
BG105060A (en)	2001-08-31
DE69913687D1 (de)	2004-01-29
HUP0102255A3 (en)	2001-12-28
PL344440A1 (en)	2001-11-05
SI1082302T1 (en)	2004-06-30
CN1148350C (zh)	2004-05-05
KR20010043906A (ko)	2001-05-25
US6495525B1 (en)	2002-12-17
KR100636713B1 (ko)	2006-10-20
UA65623C2 (en)	2004-04-15
CZ20004425A3 (en)	2001-05-16
ATE256659T1 (de)	2004-01-15
EP1082302B1 (en)	2003-12-17
NO20006023L (no)	2001-01-17
WO1999061421A1 (en)	1999-12-02
EE04639B1 (et)	2006-06-15
EA002988B1 (ru)	2002-12-26
TR200100190T2 (tr)	2001-05-21
HUP0102255A2 (hu)	2001-11-28
EA200001236A1 (ru)	2001-06-25
DE69913687T2 (de)	2004-10-07
NZ509199A (en)	2003-10-31
JP2002516309A (ja)	2002-06-04
CA2333656A1 (en)	1999-12-02
EP1082302A1 (en)	2001-03-14
SK18102000A3 (sk)	2001-07-10
ES2211096T3 (es)	2004-07-01
IL139967A0 (en)	2002-02-10
CA2333656C (en)	2008-07-29
IS5737A (is)	2000-11-28
SK285280B6 (sk)	2006-10-05
IL139967A (en)	2005-11-20
YU75500A (sh)	2002-12-10
HK1035726A1 (en)	2001-12-07
NO317990B1 (no)	2005-01-17
AU764108B2 (en)	2003-08-07
ZA200007300B (en)	2002-02-27
EE200000698A (et)	2002-06-17
AU4219299A (en)	1999-12-13
PT1082302E (pt)	2004-04-30
CN1307561A (zh)	2001-08-08

Publication	Publication Date	Title
NO20006023D0 (no)	2000-11-28	Celleadhesjonsinhibitor samt farmasöytiske sammensetninger inneholdende denne
BR9908280A (pt)	2000-10-31	Inibidores de enzimas de fosfolipase
DK0966465T3 (da)	2003-10-20	Inhibitorer af IMPDH-enzymer
HUP0201214A3 (en)	2002-11-28	Inhibitors of impdh enzyme, pharmaceutical compositions containing them and their use
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