NO20006317L - Antitrombotiske forbindelser - Google Patents

Antitrombotiske forbindelser

Info

Publication number
NO20006317L
NO20006317L NO20006317A NO20006317A NO20006317L NO 20006317 L NO20006317 L NO 20006317L NO 20006317 A NO20006317 A NO 20006317A NO 20006317 A NO20006317 A NO 20006317A NO 20006317 L NO20006317 L NO 20006317L
Authority
NO
Norway
Prior art keywords
antithrombotic compounds
antithrombotic
compounds
Prior art date
Application number
NO20006317A
Other languages
English (en)
Other versions
NO326057B1 (no
NO20006317D0 (no
Inventor
Johannes Egbertus Maria Basten
Constant Adriaan Anton Boeckel
Rogier Christian Buijsman
Cornelia Maria Dreef-Tromp
Original Assignee
Akzo Nobel Nv
Univ Leiden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv, Univ Leiden filed Critical Akzo Nobel Nv
Publication of NO20006317D0 publication Critical patent/NO20006317D0/no
Publication of NO20006317L publication Critical patent/NO20006317L/no
Publication of NO326057B1 publication Critical patent/NO326057B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20006317A 1998-06-17 2000-12-12 Antitrombotiske forbindelser samt anvendelse derav og farmasoytisk sammensetning. NO326057B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98202037 1998-06-17
PCT/EP1999/004100 WO1999065934A1 (en) 1998-06-17 1999-06-11 Antithrombotic compounds

Publications (3)

Publication Number Publication Date
NO20006317D0 NO20006317D0 (no) 2000-12-12
NO20006317L true NO20006317L (no) 2001-02-14
NO326057B1 NO326057B1 (no) 2008-09-08

Family

ID=8233825

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006317A NO326057B1 (no) 1998-06-17 2000-12-12 Antitrombotiske forbindelser samt anvendelse derav og farmasoytisk sammensetning.

Country Status (30)

Country Link
US (1) US6486129B1 (no)
EP (1) EP1087992B1 (no)
JP (1) JP4369052B2 (no)
KR (1) KR100790910B1 (no)
CN (1) CN1261450C (no)
AR (1) AR019674A1 (no)
AT (1) ATE405580T1 (no)
AU (1) AU756493B2 (no)
BR (1) BR9911300A (no)
CA (1) CA2334863C (no)
CO (1) CO5080750A1 (no)
CY (1) CY1108567T1 (no)
CZ (1) CZ299382B6 (no)
DE (1) DE69939378D1 (no)
DK (1) DK1087992T3 (no)
ES (1) ES2312210T3 (no)
HU (1) HU229088B1 (no)
ID (1) ID26614A (no)
IL (2) IL139955A0 (no)
NO (1) NO326057B1 (no)
NZ (1) NZ508623A (no)
PE (1) PE20000700A1 (no)
PL (1) PL199433B1 (no)
PT (1) PT1087992E (no)
RU (1) RU2225869C2 (no)
SK (1) SK286755B6 (no)
TR (1) TR200003710T2 (no)
TW (1) TWI221156B (no)
WO (1) WO1999065934A1 (no)
ZA (1) ZA200007075B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ508623A (en) * 1998-06-17 2002-11-26 Akzo Nobel Nv Antithrombotic peptide compounds with saccharide radicals
TWI289566B (en) 1999-12-07 2007-11-11 N.V.Organon Antithrombotic compound
DE10049937A1 (de) * 2000-10-06 2002-04-11 Knoll Ag Niedermolekulare Inhibitoren von Serinproteasen mit Polyhydroxyalkyl- und Polyhydroxycycloalkylresten
DE10300049A1 (de) * 2003-01-03 2004-07-15 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen, die Faktor VIIa inhibieren
BR0307266A (pt) * 2002-01-31 2004-12-07 Morphochem Ag Komb Chemie Compostos que inibem a atividade do fator xa
DE10330900B4 (de) * 2003-07-01 2006-09-14 Leibniz-Institut Für Polymerforschung Dresden E.V. Biomaterial mit einem modularen Beschichtungssystem zur Anwendung in Medizinprodukten mit direktem Blutkontakt
EP1574516A1 (en) * 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
TW200621794A (en) * 2004-10-06 2006-07-01 Akzo Nobel Nv Pulmonary administration of an antithrombotic compound
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
US20090111769A1 (en) * 2005-10-10 2009-04-30 De Kort Martin Antithrombotic Compound
HRP20110331T1 (hr) * 2005-10-10 2011-06-30 N.V. Organon Antikoagulantno-antitrombotski dvojni inhibitori, koji sadrže biotinski biljeg
UA94593C2 (ru) * 2005-10-10 2011-05-25 Н.В. Органон Антитромбозные двойные ингибиторы с биотиновой меткой
WO2010037180A1 (en) * 2008-10-03 2010-04-08 Glycan Biosciences Pty Ltd Anionic oligosaccharide conjugates
DK3993876T3 (en) 2019-07-01 2024-12-02 Tonix Pharma Ltd Anti-cd154 antibodies and uses thereof
AU2022205313A1 (en) 2021-01-06 2023-07-20 Tonix Pharma Limited Methods of inducing immune tolerance with modified anti-cd154 antibodies
WO2025248134A1 (en) 2024-05-31 2025-12-04 Tonix Pharma Limited Treatment methods comprising administration of modified cd154 antibodies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT84170B (pt) * 1986-01-24 1989-03-30 Sanofi Sa Processo para a preparacao de derivados n alfa-substituidos das n alfa-aril-sulfonilaminoacil d-amidinofenil-alaninamidas
DE4115468A1 (de) 1991-05-11 1992-11-12 Behringwerke Ag Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien
DE4206858A1 (de) * 1992-03-05 1993-09-09 Behringwerke Ag Glycopeptid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
ES2147216T3 (es) * 1993-09-01 2000-09-01 Akzo Nobel Nv Bisconjugados que comprenden dos sacaridos y un grupo de union.
IL120722A (en) 1996-05-08 1999-07-14 Akzo Nobel Nv Polysulfated tetrasaccharide derivatives and pharmaceutical compositions containing them
NZ508623A (en) * 1998-06-17 2002-11-26 Akzo Nobel Nv Antithrombotic peptide compounds with saccharide radicals

Also Published As

Publication number Publication date
NO326057B1 (no) 2008-09-08
AR019674A1 (es) 2002-03-13
JP2002518407A (ja) 2002-06-25
US6486129B1 (en) 2002-11-26
BR9911300A (pt) 2001-04-03
WO1999065934A1 (en) 1999-12-23
HK1034266A1 (en) 2001-10-19
CN1261450C (zh) 2006-06-28
HUP0102764A2 (hu) 2001-12-28
NO20006317D0 (no) 2000-12-12
PL345238A1 (en) 2001-12-03
ATE405580T1 (de) 2008-09-15
SK19222000A3 (sk) 2001-07-10
TR200003710T2 (tr) 2001-04-20
EP1087992A1 (en) 2001-04-04
PT1087992E (pt) 2008-10-17
CY1108567T1 (el) 2014-04-09
IL139955A (en) 2006-08-20
NZ508623A (en) 2002-11-26
RU2225869C2 (ru) 2004-03-20
ZA200007075B (en) 2002-02-28
DK1087992T3 (da) 2008-11-24
CA2334863A1 (en) 1999-12-23
CN1305494A (zh) 2001-07-25
SK286755B6 (sk) 2009-05-07
CZ299382B6 (cs) 2008-07-09
JP4369052B2 (ja) 2009-11-18
AU756493B2 (en) 2003-01-16
KR100790910B1 (ko) 2008-01-03
HUP0102764A3 (en) 2003-11-28
CZ20004735A3 (cs) 2001-08-15
AU4512999A (en) 2000-01-05
CA2334863C (en) 2011-02-15
EP1087992B1 (en) 2008-08-20
KR20010052943A (ko) 2001-06-25
PL199433B1 (pl) 2008-09-30
DE69939378D1 (de) 2008-10-02
IL139955A0 (en) 2002-02-10
ID26614A (id) 2001-01-25
TWI221156B (en) 2004-09-21
ES2312210T3 (es) 2009-02-16
CO5080750A1 (es) 2001-09-25
HU229088B1 (en) 2013-07-29
PE20000700A1 (es) 2000-08-14

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Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: UNIVERSITEIT LEIDEN, NL

MM1K Lapsed by not paying the annual fees