NO20012156L - Pyrazolopyridinderivater som selektive COX-2 inhibitorer - Google Patents

Pyrazolopyridinderivater som selektive COX-2 inhibitorer

Info

Publication number: NO20012156L
Authority: NO; Norway
Prior art keywords: inhibitors; selective cox; pyrazolopyridine derivatives; pyrazolopyridine; derivatives
Prior art date: 1998-11-03

Application number

NO20012156A

Other languages

English (en)

Other versions

NO318884B1 (no

NO20012156D0 (no

Inventor

Ian Baxter Campbell

Alan Naylor

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-03

Filing date

2001-05-02

Publication date

2001-07-02

1998-11-03 Priority claimed from GBGB9824062.5A external-priority patent/GB9824062D0/en

1999-09-03 Priority claimed from GBGB9920909.0A external-priority patent/GB9920909D0/en

2001-05-02 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2001-05-02 Publication of NO20012156D0 publication Critical patent/NO20012156D0/no

2001-07-02 Publication of NO20012156L publication Critical patent/NO20012156L/no

2005-05-18 Publication of NO318884B1 publication Critical patent/NO318884B1/no

Links

229940111134 coxibs Drugs 0.000 title 1
239000003255 cyclooxygenase 2 inhibitor Substances 0.000 title 1
150000005229 pyrazolopyridines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Virology (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Communicable Diseases (AREA)
Endocrinology (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Immunology (AREA)
Ophthalmology & Optometry (AREA)
Toxicology (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Cardiology (AREA)
AIDS & HIV (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO20012156A 1998-11-03 2001-05-02 Pyrazolopyridinderivater som selektive COX-2 inhibitorer, anvendelse og fremgangsmate for fremstillling derav, samt farmasoytisk preparat NO318884B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9824062.5A GB9824062D0 (en)	1998-11-03	1998-11-03	Chemical compounds
GBGB9920909.0A GB9920909D0 (en)	1999-09-03	1999-09-03	Chemical compounds
PCT/EP1999/008186 WO2000026216A1 (en)	1998-11-03	1999-11-01	Pyrazolopyridine derivatives as selective cox-2 inhibitors

Publications (3)

Publication Number	Publication Date
NO20012156D0 NO20012156D0 (no)	2001-05-02
NO20012156L true NO20012156L (no)	2001-07-02
NO318884B1 NO318884B1 (no)	2005-05-18

Family

ID=26314603

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20012156A NO318884B1 (no)	1998-11-03	2001-05-02	Pyrazolopyridinderivater som selektive COX-2 inhibitorer, anvendelse og fremgangsmate for fremstillling derav, samt farmasoytisk preparat

Country Status (24)

Country	Link
US (1)	US7223772B1 (no)
EP (1)	EP1127058B1 (no)
JP (1)	JP3420751B2 (no)
KR (1)	KR20010075673A (no)
CN (1)	CN1263755C (no)
AR (1)	AR021055A1 (no)
AT (1)	ATE275148T1 (no)
AU (1)	AU767464B2 (no)
BR (1)	BR9915011A (no)
CA (1)	CA2349567A1 (no)
CO (1)	CO5150164A1 (no)
CZ (1)	CZ20011556A3 (no)
DE (1)	DE69919887T2 (no)
ES (1)	ES2228127T3 (no)
GC (1)	GC0000112A (no)
HU (1)	HUP0104204A3 (no)
MY (1)	MY119689A (no)
NO (1)	NO318884B1 (no)
NZ (1)	NZ511349A (no)
PE (1)	PE20001305A1 (no)
PL (1)	PL348208A1 (no)
TR (1)	TR200101208T2 (no)
TW (1)	TW542836B (no)
WO (1)	WO2000026216A1 (no)

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EA008242B1 (ru)	1999-12-08	2007-04-27	Фармация Корпорейшн	Композиции на основе ингибитора циклооксигеназы-2 с быстро наступающим терапевтическим действием и способы лечения заболеваний
GB0002312D0 (en) *	2000-02-01	2000-03-22	Glaxo Group Ltd	Medicaments
PE20020506A1 (es) *	2000-08-22	2002-07-09	Glaxo Group Ltd	Derivados de pirazol fusionados como inhibidores de la proteina cinasa
WO2002048148A2 (en)	2000-12-15	2002-06-20	Glaxo Group Limited	Pyrazolopyridine derivatives
ATE301653T1 (de)	2000-12-15	2005-08-15	Glaxo Group Ltd	Pyrazolopyridine
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ATE364043T1 (de) *	2001-09-07	2007-06-15	Smithkline Beecham Corp	Pyrazolo-pyridine für die behandlung von herpes- ansteckungen
WO2003031446A1 (en)	2001-10-05	2003-04-17	Smithkline Beecham Corporation	Imidazo-pyridine derivatives for use in the treatment of herpes viral infection
GB0124933D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
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AU2002357740A1 (en)	2001-12-11	2003-06-23	Smithkline Beecham Corporation	Pyrazolo-pyridine derivatives as antiherpes agents
BRPI0307351B8 (pt)	2002-02-12	2021-05-25	Smithkline Beecham Corp	composto, composição farmacêutica, uso de um composto, e, processo para preparar um composto
AU2003258630A1 (en)	2002-08-19	2004-03-11	Glaxo Group Limited	Pyrimidine derivatives as selective cox-2 inhibitors
UY27939A1 (es)	2002-08-21	2004-03-31	Glaxo Group Ltd	Compuestos
UA80296C2 (en) *	2002-09-06	2007-09-10	Biogen Inc	Imidazolopyridines and methods of making and using the same
JP2006504728A (ja)	2002-10-03	2006-02-09	スミスクラインビーチャムコーポレーション	ピラソロピリジン誘導体系治療用化合物
NZ541836A (en)	2003-02-27	2008-12-24	Palau Pharma Sa	Pyrazolopyridine derivatives
GB0308186D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
GB0308185D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
GB0308201D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
ES2275218T3 (es)	2003-05-07	2007-06-01	Osteologix A/S	Sales de estroncio hidrosolubles para el tratamiento de afecciones de cartilagos y/o huesos.
GB0318814D0 (en)	2003-08-11	2003-09-10	Smithkline Beecham Corp	Novel compounds
CA2592442A1 (en)	2004-12-23	2006-06-29	Glaxo Group Limited	Pyridine compounds for the treatment of prostaglandin mediated diseases
DE102005024012A1 (de) *	2005-05-20	2006-11-23	Grünenthal GmbH	Verwendung von 2,5-disubstituierten Thiazol-4-on-Derivaten in Arzneimitteln
US7585875B2 (en)	2006-06-06	2009-09-08	Avigen, Inc.	Substituted pyrazolo[1,5-a]pyridine compounds and their methods of use
CA2676413A1 (en) *	2007-01-19	2008-07-31	Mallinckrodt Inc.	Diagnostic and therapeutic cyclooxygenase-2 binding ligands
GB0704407D0 (en)	2007-03-07	2007-04-18	Glaxo Group Ltd	Compounds
US7943658B2 (en)	2007-07-23	2011-05-17	Bristol-Myers Squibb Company	Indole indane amide compounds useful as CB2 agonists and method
UA103319C2 (en) *	2008-05-06	2013-10-10	Глаксосмитклайн Ллк	Thiazole- and oxazole-benzene sulfonamide compounds
GB0813144D0 (en)	2008-07-17	2008-08-27	Glaxo Group Ltd	Novel compounds
GB0813142D0 (en)	2008-07-17	2008-08-27	Glaxo Group Ltd	Novel compounds
WO2011012622A1 (en)	2009-07-30	2011-02-03	Glaxo Group Limited	Benzoxazinone derivatives for the treatment of glytl mediated disorders
WO2011023753A1 (en)	2009-08-27	2011-03-03	Glaxo Group Limited	Benzoxazine derivatives as glycine transport inhibitors
GB201000685D0 (en)	2010-01-15	2010-03-03	Glaxo Group Ltd	Novel compounds
GB201007789D0 (en)	2010-05-10	2010-06-23	Glaxo Group Ltd	Novel Compound
GB201007791D0 (en)	2010-05-10	2010-06-23	Glaxo Group Ltd	Novel compounds
JP5815029B2 (ja)	2010-07-09	2015-11-17	クオンベルゲンセプハルマセウトイカルスリミテッド	カルシウムチャネル遮断薬としてのテトラゾール化合物
JP6058556B2 (ja)	2011-01-19	2017-01-11	クオンベルゲンセプハルマセウトイカルスリミテッド	ＣａＶ２．２カルシウムチャンネルブロッカーとしてのピペラジン誘導体
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1999
- 1999-11-01 CN CNB99815234XA patent/CN1263755C/zh not_active Expired - Fee Related
- 1999-11-01 AT AT99955897T patent/ATE275148T1/de not_active IP Right Cessation
- 1999-11-01 PL PL99348208A patent/PL348208A1/xx not_active Application Discontinuation
- 1999-11-01 ES ES99955897T patent/ES2228127T3/es not_active Expired - Lifetime
- 1999-11-01 AR ARP990105525A patent/AR021055A1/es unknown
- 1999-11-01 DE DE69919887T patent/DE69919887T2/de not_active Expired - Fee Related
- 1999-11-01 KR KR1020017005495A patent/KR20010075673A/ko not_active Ceased
- 1999-11-01 TR TR2001/01208T patent/TR200101208T2/xx unknown
- 1999-11-01 BR BR9915011-5A patent/BR9915011A/pt not_active IP Right Cessation
- 1999-11-01 CZ CZ20011556A patent/CZ20011556A3/cs unknown
- 1999-11-01 US US09/830,836 patent/US7223772B1/en not_active Expired - Fee Related
- 1999-11-01 NZ NZ511349A patent/NZ511349A/en unknown
- 1999-11-01 WO PCT/EP1999/008186 patent/WO2000026216A1/en not_active Ceased
- 1999-11-01 AU AU12667/00A patent/AU767464B2/en not_active Ceased
- 1999-11-01 CA CA002349567A patent/CA2349567A1/en not_active Abandoned
- 1999-11-01 EP EP99955897A patent/EP1127058B1/en not_active Expired - Lifetime
- 1999-11-01 JP JP2000579604A patent/JP3420751B2/ja not_active Expired - Fee Related
- 1999-11-01 HU HU0104204A patent/HUP0104204A3/hu unknown
- 1999-11-02 GC GCP1999355 patent/GC0000112A/xx active
- 1999-11-02 CO CO99068974A patent/CO5150164A1/es unknown
- 1999-11-02 TW TW088119040A patent/TW542836B/zh not_active IP Right Cessation
- 1999-11-02 MY MYPI99004739A patent/MY119689A/en unknown
- 1999-11-03 PE PE1999001103A patent/PE20001305A1/es not_active Application Discontinuation
2001
- 2001-05-02 NO NO20012156A patent/NO318884B1/no unknown

Also Published As

Publication number	Publication date
JP2002528547A (ja)	2002-09-03
TR200101208T2 (tr)	2001-10-22
AU1266700A (en)	2000-05-22
JP3420751B2 (ja)	2003-06-30
MY119689A (en)	2005-06-30
EP1127058A1 (en)	2001-08-29
BR9915011A (pt)	2001-08-07
CZ20011556A3 (cs)	2001-11-14
CO5150164A1 (es)	2002-04-29
DE69919887T2 (de)	2005-09-15
KR20010075673A (ko)	2001-08-09
GC0000112A (en)	2005-06-29
CA2349567A1 (en)	2000-05-11
CN1332741A (zh)	2002-01-23
NO318884B1 (no)	2005-05-18
WO2000026216A1 (en)	2000-05-11
NO20012156D0 (no)	2001-05-02
NZ511349A (en)	2003-10-31
HUP0104204A3 (en)	2002-06-28
HUP0104204A2 (hu)	2002-04-29
TW542836B (en)	2003-07-21
ATE275148T1 (de)	2004-09-15
AR021055A1 (es)	2002-06-12
PL348208A1 (en)	2002-05-06
DE69919887D1 (de)	2004-10-07
US7223772B1 (en)	2007-05-29
EP1127058B1 (en)	2004-09-01
AU767464B2 (en)	2003-11-13
ES2228127T3 (es)	2005-04-01
CN1263755C (zh)	2006-07-12
PE20001305A1 (es)	2000-12-06

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